Click here to switch to the map view.

The map label for this gene is ezrA

Identifier: 49478807

GI number: 49478807

Start: 4446255

End: 4447967

Strand: Reverse

Name: ezrA

Synonym: BT9727_4383

Alternate gene names: 49478807

Gene position: 4447967-4446255 (Counterclockwise)

Preceding gene: 49478717

Following gene: 49481400

Centisome position: 84.92

GC content: 36.02

Gene sequence:

>1713_bases
ATGGATTCTATCCTGACGATCGTTATCATTGTAGTAAGCTCTATTCTAGTGCTGCTCATGATAGAGCTTGTGATAAGAAA
TCGTTCATATAAAGATATTGAAGCACTTGAGCAGTGGAAACAAGAGATAAAAGATAAACCTGTGGCAGATGAACTAAAAC
GGGTGAAAGATTTAAATATGACGGGTCAAACAGAAGAACTGTTTGGTAAATGGCGTGAAGAATGGGATGAAATTGTATCA
ACAACCATTCCGAAAGCTGAAAAAGATTTAGCGCAAGCGCGAAAATTCGCCTCGCAATTCTCCTTCCGAAAAGCAAAGCA
TGCGATGAATGAATCCATAAGTGGTTTAGATGACGCTGATAATCGTATTACAGACATTTTAAATGAATTACAGCAATTGT
TAGAAAGCCATGAAAAAAATAGCTCGGAAATCGAAGGGTTACGTGATACATATCGTAGTATGAAGAAGAGTGTTCTTGCT
CATAGACATATGTATGGAGCAGCAGAGCAGAAAATCGAAGAGATGCTAGACGCTGAATCTGAGAAATTTAAAACCTTTGA
AGAAGCAACAAACAATGGCGACTATTTAAAAGCGAGAGAAATTGTTATTAGTTTGGAAGAAGGTTTAGCAGATTTAGAAA
TCATTATTCACCAAATTCCAGATTTATTGGTAGAGTGTCAAGCGACGTTACCGGTTCAGTTGGAAGATTTATTACACGGA
CATAATGATATGGTAAGACAAGGTTATGTATTAGAGTATTTGGAAATTCCTAAAGAAGTTCGCGATATGAAGAAACAACT
ACAAATATGTTTAATGGATATACAGGAGCTTCACATAACAGAAGCGGCTGAAAAAGTAGAGAACTTAAAAACAAGTTTAG
ATGGCTTCTATGATCAACTGGAACAAGAAGTACATGCGAGACATTATGTGGAGCAAAAAACACTTTCTGTTTATGAAGAC
TTAGAAGAAATTCGCATTGAAACGATTGAAACAAAAGCAGAAACACAGCTCGTGAAACAAAGCTATCAGTTACAAGATAA
GGACATTGAGTCTCAAAAAGTAATTGAAAAGCAAATGCACATTTTAATGAAACGTTTTGAAATGTTGCAATTACGGGTTG
CGGAACAAGATATTGCCTTCTCTATTATTCGTGAGGAACTAGAAGAGATTTATGAGCAATGTGAAACATTAAAAGTACTT
CATGCAGAATATAAAGAAATGCTGCAAACGATGCGCAAAGAAGAATTTGAAGCACGTGAGAAGTTACAAGAAATGCGAAA
TACTATTTTCGAAACGAAACGCTTTATGCAAAAGTCGAATTTGCCAGGTCTTCCAGAGAGTATTATGGAAGATTTAAAAA
GAGGACAAATGGCAATGCAAGCTGTATATGAGCAATTAGAAGTGAAGCCGTTAAATATGAATGCTGTAAATAGCAGTTTA
GAAGAAGCTTACACAACTGTTAATGGTGTAGCTGAAATGACAGAAGAGTTAATTGGACAAGCGTATTTAGTTGAAAAATT
AATTCAATACGGTAATCGTTACCGCAGTCATGATGAGAACCTTGCAGAGAGCTTAAATTATGCGGAGAAATTATTCCGTG
AATATCAATACGATGCAGCTTTAGAACAAGCGGCTTCTGTACTAGAGCAACTTGAGCCTGGCGTTGTTCAAAAAATAGCT
GAATATGTAGACAATGAACAAACCCTTTCATAA

Upstream 100 bases:

>100_bases
TAGTTGTTAAATATAGGGGAATTCCCTTTTTATACATAATGCCTTCCATTTCATAAACGGAACGGACAAAAAAAGAGATA
TAACTAGGAGGCTTTTTTGC

Downstream 100 bases:

>100_bases
GGGTTTGTTTTTTTGTGTAATTTTGCAGACGATGTTGCTATAATGAATAGCGGAATACAGTAAGGTTATTCGTTTTAAAA
TATAACGGAACCTTTGAGTA

Product: septation ring formation regulator EzrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MDSILTIVIIVVSSILVLLMIELVIRNRSYKDIEALEQWKQEIKDKPVADELKRVKDLNMTGQTEELFGKWREEWDEIVS
TTIPKAEKDLAQARKFASQFSFRKAKHAMNESISGLDDADNRITDILNELQQLLESHEKNSSEIEGLRDTYRSMKKSVLA
HRHMYGAAEQKIEEMLDAESEKFKTFEEATNNGDYLKAREIVISLEEGLADLEIIIHQIPDLLVECQATLPVQLEDLLHG
HNDMVRQGYVLEYLEIPKEVRDMKKQLQICLMDIQELHITEAAEKVENLKTSLDGFYDQLEQEVHARHYVEQKTLSVYED
LEEIRIETIETKAETQLVKQSYQLQDKDIESQKVIEKQMHILMKRFEMLQLRVAEQDIAFSIIREELEEIYEQCETLKVL
HAEYKEMLQTMRKEEFEAREKLQEMRNTIFETKRFMQKSNLPGLPESIMEDLKRGQMAMQAVYEQLEVKPLNMNAVNSSL
EEAYTTVNGVAEMTEELIGQAYLVEKLIQYGNRYRSHDENLAESLNYAEKLFREYQYDAALEQAASVLEQLEPGVVQKIA
EYVDNEQTLS

Sequences:

>Translated_570_residues
MDSILTIVIIVVSSILVLLMIELVIRNRSYKDIEALEQWKQEIKDKPVADELKRVKDLNMTGQTEELFGKWREEWDEIVS
TTIPKAEKDLAQARKFASQFSFRKAKHAMNESISGLDDADNRITDILNELQQLLESHEKNSSEIEGLRDTYRSMKKSVLA
HRHMYGAAEQKIEEMLDAESEKFKTFEEATNNGDYLKAREIVISLEEGLADLEIIIHQIPDLLVECQATLPVQLEDLLHG
HNDMVRQGYVLEYLEIPKEVRDMKKQLQICLMDIQELHITEAAEKVENLKTSLDGFYDQLEQEVHARHYVEQKTLSVYED
LEEIRIETIETKAETQLVKQSYQLQDKDIESQKVIEKQMHILMKRFEMLQLRVAEQDIAFSIIREELEEIYEQCETLKVL
HAEYKEMLQTMRKEEFEAREKLQEMRNTIFETKRFMQKSNLPGLPESIMEDLKRGQMAMQAVYEQLEVKPLNMNAVNSSL
EEAYTTVNGVAEMTEELIGQAYLVEKLIQYGNRYRSHDENLAESLNYAEKLFREYQYDAALEQAASVLEQLEPGVVQKIA
EYVDNEQTLS
>Mature_570_residues
MDSILTIVIIVVSSILVLLMIELVIRNRSYKDIEALEQWKQEIKDKPVADELKRVKDLNMTGQTEELFGKWREEWDEIVS
TTIPKAEKDLAQARKFASQFSFRKAKHAMNESISGLDDADNRITDILNELQQLLESHEKNSSEIEGLRDTYRSMKKSVLA
HRHMYGAAEQKIEEMLDAESEKFKTFEEATNNGDYLKAREIVISLEEGLADLEIIIHQIPDLLVECQATLPVQLEDLLHG
HNDMVRQGYVLEYLEIPKEVRDMKKQLQICLMDIQELHITEAAEKVENLKTSLDGFYDQLEQEVHARHYVEQKTLSVYED
LEEIRIETIETKAETQLVKQSYQLQDKDIESQKVIEKQMHILMKRFEMLQLRVAEQDIAFSIIREELEEIYEQCETLKVL
HAEYKEMLQTMRKEEFEAREKLQEMRNTIFETKRFMQKSNLPGLPESIMEDLKRGQMAMQAVYEQLEVKPLNMNAVNSSL
EEAYTTVNGVAEMTEELIGQAYLVEKLIQYGNRYRSHDENLAESLNYAEKLFREYQYDAALEQAASVLEQLEPGVVQKIA
EYVDNEQTLS

Specific function: Negative regulator of ftsZ ring formation; modulates the frequency and position of ftsZ ring formation. Inhibits ftsZ ring formation at polar sites. Interacts either with ftsZ or with one of its binding partners to promote depolymerization [H]

COG id: COG4477

COG function: function code D; Negative regulator of septation ring formation

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein. Note=Colocalized with ftsZ to the nascent septal site (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ezrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010379 [H]

Pfam domain/function: PF06160 EzrA [H]

EC number: NA

Molecular weight: Translated: 66510; Mature: 66510

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSILTIVIIVVSSILVLLMIELVIRNRSYKDIEALEQWKQEIKDKPVADELKRVKDLNM
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
TGQTEELFGKWREEWDEIVSTTIPKAEKDLAQARKFASQFSFRKAKHAMNESISGLDDAD
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
NRITDILNELQQLLESHEKNSSEIEGLRDTYRSMKKSVLAHRHMYGAAEQKIEEMLDAES
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EKFKTFEEATNNGDYLKAREIVISLEEGLADLEIIIHQIPDLLVECQATLPVQLEDLLHG
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCC
HNDMVRQGYVLEYLEIPKEVRDMKKQLQICLMDIQELHITEAAEKVENLKTSLDGFYDQL
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQEVHARHYVEQKTLSVYEDLEEIRIETIETKAETQLVKQSYQLQDKDIESQKVIEKQMH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ILMKRFEMLQLRVAEQDIAFSIIREELEEIYEQCETLKVLHAEYKEMLQTMRKEEFEARE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLQEMRNTIFETKRFMQKSNLPGLPESIMEDLKRGQMAMQAVYEQLEVKPLNMNAVNSSL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
EEAYTTVNGVAEMTEELIGQAYLVEKLIQYGNRYRSHDENLAESLNYAEKLFREYQYDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LEQAASVLEQLEPGVVQKIAEYVDNEQTLS
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDSILTIVIIVVSSILVLLMIELVIRNRSYKDIEALEQWKQEIKDKPVADELKRVKDLNM
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
TGQTEELFGKWREEWDEIVSTTIPKAEKDLAQARKFASQFSFRKAKHAMNESISGLDDAD
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
NRITDILNELQQLLESHEKNSSEIEGLRDTYRSMKKSVLAHRHMYGAAEQKIEEMLDAES
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EKFKTFEEATNNGDYLKAREIVISLEEGLADLEIIIHQIPDLLVECQATLPVQLEDLLHG
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCC
HNDMVRQGYVLEYLEIPKEVRDMKKQLQICLMDIQELHITEAAEKVENLKTSLDGFYDQL
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQEVHARHYVEQKTLSVYEDLEEIRIETIETKAETQLVKQSYQLQDKDIESQKVIEKQMH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ILMKRFEMLQLRVAEQDIAFSIIREELEEIYEQCETLKVLHAEYKEMLQTMRKEEFEARE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLQEMRNTIFETKRFMQKSNLPGLPESIMEDLKRGQMAMQAVYEQLEVKPLNMNAVNSSL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
EEAYTTVNGVAEMTEELIGQAYLVEKLIQYGNRYRSHDENLAESLNYAEKLFREYQYDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LEQAASVLEQLEPGVVQKIAEYVDNEQTLS
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA