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The map label for this gene is gntP

Identifier: 49478784

GI number: 49478784

Start: 4620178

End: 4620930

Strand: Reverse

Name: gntP

Synonym: BT9727_4574

Alternate gene names: 49478784

Gene position: 4620930-4620178 (Counterclockwise)

Preceding gene: 49478785

Following gene: 49478783

Centisome position: 88.22

GC content: 35.06

Gene sequence:

>753_bases
TTGAATTGTATAGATTTAGTTAAGTTTATCGTATCGGTTATACCTGAAAATGAACCAGAGCTTATTCGAGTTACGACAGT
ATCAACTGATTTACCAAGCCGTAAAGTTTCGTTTTTTATCATTTTAATGCCGGTCGTTTTAATGATTTTATCAGTAGTTG
CGCCATATATTTCATTACCGAAAAAGATGACTGAATTTTTTGTATTTATTGGAAATCCAGTAATTGCTTTACTTATTTCA
TGTTTCGCAGCATTTTATTTACTTGGAATAAGACAAGGAATTAATAAAAAGATGATTAAAAAATTAACAGACGAAAGTTT
ATTACCGGTCGGTTCCATTATTTTAATTATCGGTGCAGGCGGTGGATTTAAACAAATATTAATTGAAAGCGGTGTTGGAA
CGGCGATTGCGCAAATGGCAGAACATATATCGTTATCACCAATCGTATTAGCTTTCATGGTAGCCGGTTTAATTCGAATA
GCGACCGGATCAGCTACTGTAGCATTAACGACAGCAGCAGGAATTGTTTCGCCGGTTATTCAGCACATGTCTGGTGTGAA
TTTAGAATTGCTCGTTATAGCAACCGGTGCAGGCTCATTAATGTTTTCTCACGTAAATGATGCAGGGTTCTGGCTTGTAA
AAGAATATTTAGGTTTGACAGTAAAAGAAACGTTTAAAACGTGGACAGTGCTAGAGACATTGTTATCATTTATTGCATTC
GGTTTTGCCCTTGTATTGAATATGTTTCTTTAA

Upstream 100 bases:

>100_bases
GATAATAGGAGGTAACGATACTGCCTCGTGTGGAGTGTTATACCCCTCGTCCCTTTGGGGCTGCGAGAACACGATGAAGC
GCTAACTTGTGTAAATTTGA

Downstream 100 bases:

>100_bases
AAGATACCTGAATAGGTATCTTTTTTTGATGAAGCCCAATTGCCAAAACAAGCCCGTTTTTAAGTAAGCCAAGCTTCCTA
TTCGCCCTGAAAACATACTA

Product: gluconate permease

Products: gluconate [Cytoplasm]; L-idonate [Cytoplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNCIDLVKFIVSVIPENEPELIRVTTVSTDLPSRKVSFFIILMPVVLMILSVVAPYISLPKKMTEFFVFIGNPVIALLIS
CFAAFYLLGIRQGINKKMIKKLTDESLLPVGSIILIIGAGGGFKQILIESGVGTAIAQMAEHISLSPIVLAFMVAGLIRI
ATGSATVALTTAAGIVSPVIQHMSGVNLELLVIATGAGSLMFSHVNDAGFWLVKEYLGLTVKETFKTWTVLETLLSFIAF
GFALVLNMFL

Sequences:

>Translated_250_residues
MNCIDLVKFIVSVIPENEPELIRVTTVSTDLPSRKVSFFIILMPVVLMILSVVAPYISLPKKMTEFFVFIGNPVIALLIS
CFAAFYLLGIRQGINKKMIKKLTDESLLPVGSIILIIGAGGGFKQILIESGVGTAIAQMAEHISLSPIVLAFMVAGLIRI
ATGSATVALTTAAGIVSPVIQHMSGVNLELLVIATGAGSLMFSHVNDAGFWLVKEYLGLTVKETFKTWTVLETLLSFIAF
GFALVLNMFL
>Mature_250_residues
MNCIDLVKFIVSVIPENEPELIRVTTVSTDLPSRKVSFFIILMPVVLMILSVVAPYISLPKKMTEFFVFIGNPVIALLIS
CFAAFYLLGIRQGINKKMIKKLTDESLLPVGSIILIIGAGGGFKQILIESGVGTAIAQMAEHISLSPIVLAFMVAGLIRI
ATGSATVALTTAAGIVSPVIQHMSGVNLELLVIATGAGSLMFSHVNDAGFWLVKEYLGLTVKETFKTWTVLETLLSFIAF
GFALVLNMFL

Specific function: Transport Of Gluconate And L-Idonate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI1790716, Length=223, Percent_Identity=44.8430493273543, Blast_Score=174, Evalue=3e-45,
Organism=Escherichia coli, GI48994935, Length=246, Percent_Identity=43.9024390243902, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI48994939, Length=188, Percent_Identity=43.0851063829787, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1790776, Length=227, Percent_Identity=39.2070484581498, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1788707, Length=219, Percent_Identity=36.0730593607306, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI2367370, Length=260, Percent_Identity=36.5384615384615, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1789097, Length=202, Percent_Identity=36.6336633663366, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 26922; Mature: 26922

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCIDLVKFIVSVIPENEPELIRVTTVSTDLPSRKVSFFIILMPVVLMILSVVAPYISLP
CCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
KKMTEFFVFIGNPVIALLISCFAAFYLLGIRQGINKKMIKKLTDESLLPVGSIILIIGAG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEEEEECC
GGFKQILIESGVGTAIAQMAEHISLSPIVLAFMVAGLIRIATGSATVALTTAAGIVSPVI
CCHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
QHMSGVNLELLVIATGAGSLMFSHVNDAGFWLVKEYLGLTVKETFKTWTVLETLLSFIAF
HHHCCCCEEEEEEEECCCHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
GFALVLNMFL
HHHHHHHHHC
>Mature Secondary Structure
MNCIDLVKFIVSVIPENEPELIRVTTVSTDLPSRKVSFFIILMPVVLMILSVVAPYISLP
CCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
KKMTEFFVFIGNPVIALLISCFAAFYLLGIRQGINKKMIKKLTDESLLPVGSIILIIGAG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEEEEECC
GGFKQILIESGVGTAIAQMAEHISLSPIVLAFMVAGLIRIATGSATVALTTAAGIVSPVI
CCHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
QHMSGVNLELLVIATGAGSLMFSHVNDAGFWLVKEYLGLTVKETFKTWTVLETLLSFIAF
HHHCCCCEEEEEEEECCCHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
GFALVLNMFL
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: gluconate [Periplasm]; Proton [Periplasm]; L-idonate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] Proton [Periplasm] + L-idonate [Periplasm] = L-idonate [Cytoplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]