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The map label for this gene is luxS

Identifier: 49478761

GI number: 49478761

Start: 4574101

End: 4574574

Strand: Reverse

Name: luxS

Synonym: BT9727_4525

Alternate gene names: 49478761

Gene position: 4574574-4574101 (Counterclockwise)

Preceding gene: 49481366

Following gene: 49480728

Centisome position: 87.34

GC content: 35.23

Gene sequence:

>474_bases
ATGCCATCAGTAGAAAGCTTTGAATTAGATCATACGATTGTAAAGGCACCTTATGTAAGACATTGCGGAGTTCACAATGT
AGGTAGTGACGGTATTGTAAATAAATTTGATATTCGTTTTTGCCAACCGAATAAACAAGCGATGAAACCAGATGTTATTC
ATACGTTAGAACATTTATTAGCATTTAATTTACGTAAATATATTGATCGTTATCCGCATTTCGATATTATCGATATTTCA
CCAATGGGCTGCCAAACAGGATACTACCTTGTAGTAAGCGGAACACCGACAGTTCGAGAAATCATTGATTTATTAGAATT
AACATTAAAAGATGCGGTTCAAATTACAGAAATTCCAGCTGCAAATGAAACGCAATGTGGTCAAGCGAAGCTTCACGATT
TAGAAGGAGCAAAACGCTTAATGAACTTCTGGTTAAGCCAAGATAAAGATGAACTTGAGAAAGTATTTGGATAG

Upstream 100 bases:

>100_bases
AGTATTATAGCACGACTGTACATAATACTTTACTAATGTGCATTTCCGTTATATCATATTGGATATAACGGAATTAAATT
AAAAGCGGGAGAGATGTTGT

Downstream 100 bases:

>100_bases
GAAGAAAAACTGCCTGTGAAAGGGCAGTTTTTTTTTGTCATGATAATAAATAAAATTATATCGACGATTTTTCGAATATA
TCGACCGTAACTTGAAATAT

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MPSVESFELDHTIVKAPYVRHCGVHNVGSDGIVNKFDIRFCQPNKQAMKPDVIHTLEHLLAFNLRKYIDRYPHFDIIDIS
PMGCQTGYYLVVSGTPTVREIIDLLELTLKDAVQITEIPAANETQCGQAKLHDLEGAKRLMNFWLSQDKDELEKVFG

Sequences:

>Translated_157_residues
MPSVESFELDHTIVKAPYVRHCGVHNVGSDGIVNKFDIRFCQPNKQAMKPDVIHTLEHLLAFNLRKYIDRYPHFDIIDIS
PMGCQTGYYLVVSGTPTVREIIDLLELTLKDAVQITEIPAANETQCGQAKLHDLEGAKRLMNFWLSQDKDELEKVFG
>Mature_156_residues
PSVESFELDHTIVKAPYVRHCGVHNVGSDGIVNKFDIRFCQPNKQAMKPDVIHTLEHLLAFNLRKYIDRYPHFDIIDISP
MGCQTGYYLVVSGTPTVREIIDLLELTLKDAVQITEIPAANETQCGQAKLHDLEGAKRLMNFWLSQDKDELEKVFG

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=151, Percent_Identity=38.4105960264901, Blast_Score=114, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_BACAA (C3PCE7)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002869066.1
- ProteinModelPortal:   C3PCE7
- SMR:   C3PCE7
- EnsemblBacteria:   EBBACT00000126981
- GeneID:   7850859
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_5058
- GeneTree:   EBGT00050000002559
- ProtClustDB:   PRK02260
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 17856; Mature: 17725

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSVESFELDHTIVKAPYVRHCGVHNVGSDGIVNKFDIRFCQPNKQAMKPDVIHTLEHLL
CCCCCCCCCCHHHHCCCHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHH
AFNLRKYIDRYPHFDIIDISPMGCQTGYYLVVSGTPTVREIIDLLELTLKDAVQITEIPA
HHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
ANETQCGQAKLHDLEGAKRLMNFWLSQDKDELEKVFG
CCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure 
PSVESFELDHTIVKAPYVRHCGVHNVGSDGIVNKFDIRFCQPNKQAMKPDVIHTLEHLL
CCCCCCCCCHHHHCCCHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHH
AFNLRKYIDRYPHFDIIDISPMGCQTGYYLVVSGTPTVREIIDLLELTLKDAVQITEIPA
HHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
ANETQCGQAKLHDLEGAKRLMNFWLSQDKDELEKVFG
CCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA