Click here to switch to the map view.

The map label for this gene is aroK

Identifier: 49478589

GI number: 49478589

Start: 4044975

End: 4045472

Strand: Reverse

Name: aroK

Synonym: BT9727_3977

Alternate gene names: 49478589

Gene position: 4045472-4044975 (Counterclockwise)

Preceding gene: 49480949

Following gene: 49480643

Centisome position: 77.24

GC content: 35.54

Gene sequence:

>498_bases
ATGAAATCTATATACATAACCGGTTATATGGGAGCTGGGAAAACAACAATTGGAAAAGCGTTAAGTAAAGAACTTCATAT
GGATGTTGTAGATACAGATCAAAAAATTGAAGAGAAGCAAGAGAAGGCAATTCTTGATATTTTTGCCGAAGAAGGTGAAA
TGGCTTTTCGAGAATATGAAAGTGAGATGTTACGTTCATTACCCGTTCGTAATGCAATTATTACAACTGGCGGCGGAATC
ATTGAGCGAGAGGAAAACCGAAAGTGGATGAAGGAAAATGGAATTGTCGTGTATTTATATTGCGATCCACATGTAATTGC
AGAGAGGCTTCGTGAAGATACGACACGTCCACTATTTCAGAAGAAAGATATAGATGCATTTGTAACGAAATTTGAATCGC
GCCGAGCTTATTATGAAGAGGCTCATATTCATATTGATACGACGAATAAGTCTGTAAAGCAAATTATGAATGAATTAAAA
GAAAAGATTAATGAATAA

Upstream 100 bases:

>100_bases
GTTCTTCAATGCATAAGGAGAACAAAACGTTTTTTTATTAAATAAAGGAGCATCTTTCGTTATAATAACAAGTAATACAT
GACGATTGAGAGGAAAGAAC

Downstream 100 bases:

>100_bases
AAAAGTGGACATACTAATCAAGTAGAGGTGATGATAATATGTCTACTAATGATTATGTTCGCTTTGTGACACAACAGTTT
GTGTCGTATATGGATGCTCC

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MKSIYITGYMGAGKTTIGKALSKELHMDVVDTDQKIEEKQEKAILDIFAEEGEMAFREYESEMLRSLPVRNAIITTGGGI
IEREENRKWMKENGIVVYLYCDPHVIAERLREDTTRPLFQKKDIDAFVTKFESRRAYYEEAHIHIDTTNKSVKQIMNELK
EKINE

Sequences:

>Translated_165_residues
MKSIYITGYMGAGKTTIGKALSKELHMDVVDTDQKIEEKQEKAILDIFAEEGEMAFREYESEMLRSLPVRNAIITTGGGI
IEREENRKWMKENGIVVYLYCDPHVIAERLREDTTRPLFQKKDIDAFVTKFESRRAYYEEAHIHIDTTNKSVKQIMNELK
EKINE
>Mature_165_residues
MKSIYITGYMGAGKTTIGKALSKELHMDVVDTDQKIEEKQEKAILDIFAEEGEMAFREYESEMLRSLPVRNAIITTGGGI
IEREENRKWMKENGIVVYLYCDPHVIAERLREDTTRPLFQKKDIDAFVTKFESRRAYYEEAHIHIDTTNKSVKQIMNELK
EKINE

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786587, Length=169, Percent_Identity=36.094674556213, Blast_Score=101, Evalue=2e-23,
Organism=Escherichia coli, GI87082255, Length=165, Percent_Identity=32.7272727272727, Blast_Score=89, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320332, Length=149, Percent_Identity=29.5302013422819, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 19224; Mature: 19224

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIYITGYMGAGKTTIGKALSKELHMDVVDTDQKIEEKQEKAILDIFAEEGEMAFREYE
CCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SEMLRSLPVRNAIITTGGGIIEREENRKWMKENGIVVYLYCDPHVIAERLREDTTRPLFQ
HHHHHHCCCCCEEEECCCCEEEECCCHHHHHHCCEEEEEEECHHHHHHHHHHHCCCCHHH
KKDIDAFVTKFESRRAYYEEAHIHIDTTNKSVKQIMNELKEKINE
HCCHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSIYITGYMGAGKTTIGKALSKELHMDVVDTDQKIEEKQEKAILDIFAEEGEMAFREYE
CCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SEMLRSLPVRNAIITTGGGIIEREENRKWMKENGIVVYLYCDPHVIAERLREDTTRPLFQ
HHHHHHCCCCCEEEECCCCEEEECCCHHHHHHCCEEEEEEECHHHHHHHHHHHCCCCHHH
KKDIDAFVTKFESRRAYYEEAHIHIDTTNKSVKQIMNELKEKINE
HCCHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA