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The map label for this gene is pgsA

Identifier: 49478371

GI number: 49478371

Start: 3614699

End: 3615277

Strand: Reverse

Name: pgsA

Synonym: BT9727_3523

Alternate gene names: 49478371

Gene position: 3615277-3614699 (Counterclockwise)

Preceding gene: 49479420

Following gene: 49478370

Centisome position: 69.02

GC content: 35.58

Gene sequence:

>579_bases
GTGAATTTACCAAATAAAATTACGATATCTAGAATCTGCTTAATTCCAATTTTTATGGTAATTATGTTAGCACCCTTTGA
TTGGGGTTCATACACAATTGGTGATGTTGATTTACCAATTCAACATTTAGTAGGAGCGCTTATCTTTATTGTTGCTTCGG
CTACAGATTGGATTGATGGACATTACGCAAGAAAGTATAATCTTGTAACGAATTTAGGAAAGTTCCTTGACCCGTTAGCT
GATAAATTACTTGTTTCAGCAGCACTTATCACGTTAGTTGAGATGCAATACGTACCTGCTTGGATCGTTATTGTCATTAT
AAGCCGTGAGTTTGCGGTAACTGGTTTACGTCTTGTACTCGCTGGAACAGGAGAAGTAGTTGCGGCAAATCAGCTAGGAA
AAATTAAGACATGGACACAAATTATCGCGATTGCAGCATATTTATTACACGATGTACCTTTAAACTTAATCCATATTCCG
GTAGCTGACATCTTTATATGGATTGCATTAATTTTTACTGTTATTTCAGGATGGGATTATTTCTGGAAAAATAGAGCTGC
TTTTGTAAACTCAAAATAG

Upstream 100 bases:

>100_bases
GATAAAAAACCAAGGGGTAGAGCAACCTGCACAATAACAGTCATCGCTTCGATGACTTTTTTCAATGAACAAATGTTTTT
GATATGATGGAGGAATAGCT

Downstream 100 bases:

>100_bases
AAGTTTATGGGGGAATTGGGATGAATGCGGAGATTATTGCGGTTGGAACGGAATTATTACTTGGACAAATTGCAAATACA
AATGCCCAGTTTTTATCTGA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MNLPNKITISRICLIPIFMVIMLAPFDWGSYTIGDVDLPIQHLVGALIFIVASATDWIDGHYARKYNLVTNLGKFLDPLA
DKLLVSAALITLVEMQYVPAWIVIVIISREFAVTGLRLVLAGTGEVVAANQLGKIKTWTQIIAIAAYLLHDVPLNLIHIP
VADIFIWIALIFTVISGWDYFWKNRAAFVNSK

Sequences:

>Translated_192_residues
MNLPNKITISRICLIPIFMVIMLAPFDWGSYTIGDVDLPIQHLVGALIFIVASATDWIDGHYARKYNLVTNLGKFLDPLA
DKLLVSAALITLVEMQYVPAWIVIVIISREFAVTGLRLVLAGTGEVVAANQLGKIKTWTQIIAIAAYLLHDVPLNLIHIP
VADIFIWIALIFTVISGWDYFWKNRAAFVNSK
>Mature_192_residues
MNLPNKITISRICLIPIFMVIMLAPFDWGSYTIGDVDLPIQHLVGALIFIVASATDWIDGHYARKYNLVTNLGKFLDPLA
DKLLVSAALITLVEMQYVPAWIVIVIISREFAVTGLRLVLAGTGEVVAANQLGKIKTWTQIIAIAAYLLHDVPLNLIHIP
VADIFIWIALIFTVISGWDYFWKNRAAFVNSK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=149, Percent_Identity=37.5838926174497, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21404; Mature: 21404

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPNKITISRICLIPIFMVIMLAPFDWGSYTIGDVDLPIQHLVGALIFIVASATDWIDG
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCHHHCC
HYARKYNLVTNLGKFLDPLADKLLVSAALITLVEMQYVPAWIVIVIISREFAVTGLRLVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
AGTGEVVAANQLGKIKTWTQIIAIAAYLLHDVPLNLIHIPVADIFIWIALIFTVISGWDY
ECCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHCCHH
FWKNRAAFVNSK
HHCCCCCCCCCC
>Mature Secondary Structure
MNLPNKITISRICLIPIFMVIMLAPFDWGSYTIGDVDLPIQHLVGALIFIVASATDWIDG
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCHHHCC
HYARKYNLVTNLGKFLDPLADKLLVSAALITLVEMQYVPAWIVIVIISREFAVTGLRLVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
AGTGEVVAANQLGKIKTWTQIIAIAAYLLHDVPLNLIHIPVADIFIWIALIFTVISGWDY
ECCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHCCHH
FWKNRAAFVNSK
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]