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The map label for this gene is npr

Identifier: 49478205

GI number: 49478205

Start: 3241232

End: 3242929

Strand: Reverse

Name: npr

Synonym: BT9727_3170

Alternate gene names: 49478205

Gene position: 3242929-3241232 (Counterclockwise)

Preceding gene: 49479004

Following gene: 49479005

Centisome position: 61.92

GC content: 34.86

Gene sequence:

>1698_bases
ATGAATAATTTCGTAAAGTTAGGTTTAACTACAGGAGTGGTGTTATCGGCGATTATGCCTTATGGAGGAGTACATGCGGC
AACAGAAGATTTAAAAGTGGAAACAAAGGAAGATACGTTCCGAACAGGTAATTTAACAGCACCTTCTCAAAAATCGGCAG
AAAATGTAGTAAAGGATGCGCTGAAAGGGAAAACAGAACAAGCATTATCCTCAAAGCAAGTTAATACGGAATCAAAAGTT
AATTATAATGTGACGCAAAGTCGTAAATCTTATGATGGTACTACATTGGTGCGTCTTCAACAAACATATGAAGGACGTGA
TGTATACGGATATCAACTAACAGCACATATTAATGATGATGGTGTACTTACGAGTATTTCGGGGGATAGTGCCCAAGACC
TACAACAACAGGAAGATTTGAAACAACCTATTACTCTATCAGAAGAGGATGCAAAGAAGCAGCTTTTTAAAATCTATGGG
GATAATCTTACATTTGTTGAAGAACCAGAAATTAAACAAGTGGTATATGTAGATGAAAATACAAATAAAGCTACAAACGC
ATATCAAATTACTTTTAGTGCCTCTACACCTGAATATGTATCTGGTACGGTATTAATTGATGCTTTTGTTGGGGATCTAT
TAAAAGAACTCGTTCAAAAATTGGGTATACAAGTAGATAGCAGTATCGTTCAATCTGCAACAGCAAATAAATCACAAGAT
CCTTCGAAATTAATAGGCACAGGAAAAGATGATTTAGGTATGAATCGTACGTTTGGAATTTCACAGCGAAGTGATGGAAC
GTACACTCTTGCAGATTATTCTCGTGGTAAGGGAATTGAAACGTATACTGCGAATTATAAAGATTATAATAATTATAGAA
GAAATGTATGGGGGTATTTGGATGATTTAGTAACAAGTAATTCTACAAATTTTACAGATCCTAAAGCAGTTAGTGCACAT
TATTTAGCAACGAAAGTATATGATTTTTATCAAGAAAAATATAGTCGTAATAGCTTTGATAATAATGGACAAAAAGTAAT
TTCAGTCGTTCATGGCTGGAATACAAATGGTAAGAATATAGGAAATCCTAAGCAGTGGTTTAATGCATTTAGTAATGGGG
CTATGCTAGTATACGGAGATCCAATTGTTAGAGCATTTGATGTGGCAGGACATGAGTTTACACACGCGGTTACAAGAAAT
GAGTCTGGACTTGAGTACGCAGGAGAAGCTGGTGCCATTAATGAGGCTCTATCTGATATTTTAGGGGTAGCAGTTGAAAA
GTATGCCAATAACGGAAAGTTCAATTGGACAATGGGGGAACAATCAGGTCGTATATTTAGAGATATGAAAAACCCATCAT
CTATCTCTTCTAGATATCCAGAAGATTATAGACATTATAACAATTTACCTATTGATGCTGATCACGATTATGGTGGTGTA
CACACGAACTCTAGCATTATAAATAAAGTAGCTTATTTAATTGCTAGTGGTGGAAATCATAATGGAGTAAATGTACAAGG
CATTGGGGAAGATAAAATGTTTGATATTTTCTATTATGCAAATACCGATGAATTAAATATGACTTCTGATTTTAAAGAAT
TAAAAGAAGCTTGTATTCGTGTAGCAACGAACTTATATGGTAAAGACTCATCAGAAGTACAAGCCGTCCAACAAGCCTTT
AAAGCAGCTTATATTTAA

Upstream 100 bases:

>100_bases
CATGTAAAATTGATTGACTATAGTTAAAAATTTTATCTATGCTTAAAATTCTAAAATAAATTTATTTAATTTAATAATAA
GATTATAAAGGAGTAAGAAT

Downstream 100 bases:

>100_bases
TACTATTGTGATGAATTGAAAACTCTCTTATTTTAATATAATGATTGGTTTGTATATGTAGGCAAAAACCTTGTAGAATT
TTTCTGCAAGGTTTTTTAGA

Product: neutral protease (bacillolysin)

Products: NA

Alternate protein names: Neutral protease [H]

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MNNFVKLGLTTGVVLSAIMPYGGVHAATEDLKVETKEDTFRTGNLTAPSQKSAENVVKDALKGKTEQALSSKQVNTESKV
NYNVTQSRKSYDGTTLVRLQQTYEGRDVYGYQLTAHINDDGVLTSISGDSAQDLQQQEDLKQPITLSEEDAKKQLFKIYG
DNLTFVEEPEIKQVVYVDENTNKATNAYQITFSASTPEYVSGTVLIDAFVGDLLKELVQKLGIQVDSSIVQSATANKSQD
PSKLIGTGKDDLGMNRTFGISQRSDGTYTLADYSRGKGIETYTANYKDYNNYRRNVWGYLDDLVTSNSTNFTDPKAVSAH
YLATKVYDFYQEKYSRNSFDNNGQKVISVVHGWNTNGKNIGNPKQWFNAFSNGAMLVYGDPIVRAFDVAGHEFTHAVTRN
ESGLEYAGEAGAINEALSDILGVAVEKYANNGKFNWTMGEQSGRIFRDMKNPSSISSRYPEDYRHYNNLPIDADHDYGGV
HTNSSIINKVAYLIASGGNHNGVNVQGIGEDKMFDIFYYANTDELNMTSDFKELKEACIRVATNLYGKDSSEVQAVQQAF
KAAYI

Sequences:

>Translated_565_residues
MNNFVKLGLTTGVVLSAIMPYGGVHAATEDLKVETKEDTFRTGNLTAPSQKSAENVVKDALKGKTEQALSSKQVNTESKV
NYNVTQSRKSYDGTTLVRLQQTYEGRDVYGYQLTAHINDDGVLTSISGDSAQDLQQQEDLKQPITLSEEDAKKQLFKIYG
DNLTFVEEPEIKQVVYVDENTNKATNAYQITFSASTPEYVSGTVLIDAFVGDLLKELVQKLGIQVDSSIVQSATANKSQD
PSKLIGTGKDDLGMNRTFGISQRSDGTYTLADYSRGKGIETYTANYKDYNNYRRNVWGYLDDLVTSNSTNFTDPKAVSAH
YLATKVYDFYQEKYSRNSFDNNGQKVISVVHGWNTNGKNIGNPKQWFNAFSNGAMLVYGDPIVRAFDVAGHEFTHAVTRN
ESGLEYAGEAGAINEALSDILGVAVEKYANNGKFNWTMGEQSGRIFRDMKNPSSISSRYPEDYRHYNNLPIDADHDYGGV
HTNSSIINKVAYLIASGGNHNGVNVQGIGEDKMFDIFYYANTDELNMTSDFKELKEACIRVATNLYGKDSSEVQAVQQAF
KAAYI
>Mature_565_residues
MNNFVKLGLTTGVVLSAIMPYGGVHAATEDLKVETKEDTFRTGNLTAPSQKSAENVVKDALKGKTEQALSSKQVNTESKV
NYNVTQSRKSYDGTTLVRLQQTYEGRDVYGYQLTAHINDDGVLTSISGDSAQDLQQQEDLKQPITLSEEDAKKQLFKIYG
DNLTFVEEPEIKQVVYVDENTNKATNAYQITFSASTPEYVSGTVLIDAFVGDLLKELVQKLGIQVDSSIVQSATANKSQD
PSKLIGTGKDDLGMNRTFGISQRSDGTYTLADYSRGKGIETYTANYKDYNNYRRNVWGYLDDLVTSNSTNFTDPKAVSAH
YLATKVYDFYQEKYSRNSFDNNGQKVISVVHGWNTNGKNIGNPKQWFNAFSNGAMLVYGDPIVRAFDVAGHEFTHAVTRN
ESGLEYAGEAGAINEALSDILGVAVEKYANNGKFNWTMGEQSGRIFRDMKNPSSISSRYPEDYRHYNNLPIDADHDYGGV
HTNSSIINKVAYLIASGGNHNGVNVQGIGEDKMFDIFYYANTDELNMTSDFKELKEACIRVATNLYGKDSSEVQAVQQAF
KAAYI

Specific function: Extracellular zinc metalloprotease [H]

COG id: COG3227

COG function: function code E; Zinc metalloprotease (elastase)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005075
- InterPro:   IPR013856
- InterPro:   IPR001570
- InterPro:   IPR011096 [H]

Pfam domain/function: PF07504 FTP; PF03413 PepSY; PF01447 Peptidase_M4; PF02868 Peptidase_M4_C [H]

EC number: =3.4.24.28 [H]

Molecular weight: Translated: 62583; Mature: 62583

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFVKLGLTTGVVLSAIMPYGGVHAATEDLKVETKEDTFRTGNLTAPSQKSAENVVKDA
CCCEEEECHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEECCCCCCCCHHHHHHHHHHH
LKGKTEQALSSKQVNTESKVNYNVTQSRKSYDGTTLVRLQQTYEGRDVYGYQLTAHINDD
HCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCEEEEEEEEEEECCC
GVLTSISGDSAQDLQQQEDLKQPITLSEEDAKKQLFKIYGDNLTFVEEPEIKQVVYVDEN
CEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECC
TNKATNAYQITFSASTPEYVSGTVLIDAFVGDLLKELVQKLGIQVDSSIVQSATANKSQD
CCCCCCEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
PSKLIGTGKDDLGMNRTFGISQRSDGTYTLADYSRGKGIETYTANYKDYNNYRRNVWGYL
CHHHHCCCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHH
DDLVTSNSTNFTDPKAVSAHYLATKVYDFYQEKYSRNSFDNNGQKVISVVHGWNTNGKNI
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCC
GNPKQWFNAFSNGAMLVYGDPIVRAFDVAGHEFTHAVTRNESGLEYAGEAGAINEALSDI
CCHHHHHHHHCCCEEEEECCCHHEEHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LGVAVEKYANNGKFNWTMGEQSGRIFRDMKNPSSISSRYPEDYRHYNNLPIDADHDYGGV
HHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCHHHHHCCCHHHHHCCCCCCCCCCCCCCE
HTNSSIINKVAYLIASGGNHNGVNVQGIGEDKMFDIFYYANTDELNMTSDFKELKEACIR
ECCHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHH
VATNLYGKDSSEVQAVQQAFKAAYI
HHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNFVKLGLTTGVVLSAIMPYGGVHAATEDLKVETKEDTFRTGNLTAPSQKSAENVVKDA
CCCEEEECHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEECCCCCCCCHHHHHHHHHHH
LKGKTEQALSSKQVNTESKVNYNVTQSRKSYDGTTLVRLQQTYEGRDVYGYQLTAHINDD
HCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCEEEEEEEEEEECCC
GVLTSISGDSAQDLQQQEDLKQPITLSEEDAKKQLFKIYGDNLTFVEEPEIKQVVYVDEN
CEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECC
TNKATNAYQITFSASTPEYVSGTVLIDAFVGDLLKELVQKLGIQVDSSIVQSATANKSQD
CCCCCCEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
PSKLIGTGKDDLGMNRTFGISQRSDGTYTLADYSRGKGIETYTANYKDYNNYRRNVWGYL
CHHHHCCCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHH
DDLVTSNSTNFTDPKAVSAHYLATKVYDFYQEKYSRNSFDNNGQKVISVVHGWNTNGKNI
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCC
GNPKQWFNAFSNGAMLVYGDPIVRAFDVAGHEFTHAVTRNESGLEYAGEAGAINEALSDI
CCHHHHHHHHCCCEEEEECCCHHEEHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LGVAVEKYANNGKFNWTMGEQSGRIFRDMKNPSSISSRYPEDYRHYNNLPIDADHDYGGV
HHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCHHHHHCCCHHHHHCCCCCCCCCCCCCCE
HTNSSIINKVAYLIASGGNHNGVNVQGIGEDKMFDIFYYANTDELNMTSDFKELKEACIR
ECCHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHH
VATNLYGKDSSEVQAVQQAFKAAYI
HHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7764969 [H]