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The map label for this gene is acyII [H]

Identifier: 49478107

GI number: 49478107

Start: 3113060

End: 3115450

Strand: Reverse

Name: acyII [H]

Synonym: BT9727_3031

Alternate gene names: 49478107

Gene position: 3115450-3113060 (Counterclockwise)

Preceding gene: 49479509

Following gene: 49478106

Centisome position: 59.48

GC content: 38.52

Gene sequence:

>2391_bases
ATGGAAGTTGTTATAAAGAAGAAACGAACTAGGGGTAAGAAAATTTTCATTTGGTCTAGTAGTATCGTTCTTTTATTAGT
TATTTGTACAGCGATTTTTTTGAACATATATACGCTGAAATCTGTGCCAAAGATAGATGGAACGATAAAACTAGAGGATT
TACAACGTGCTGTTACGGTAAAGCGAGATAGTAAAGGAGTACCACATATTAAAGCGGAAAATGCGCATGATTTATATTTT
TCGCAAGGATATGTACAAGCGCAAGATCGTTTGTTTCAAATGGATTTAAGTAGAAGGCAAGCTTCTGGTATGCTGAGTGA
GGTTGTAGGAGAAGCAGCTGTTGATCGAGATAAGTTGTTTCGAACGCTCGGTTTACGGCGAGCAGCCGAAGCGTCTGTTA
GTCAATATGATGGGGAGGCGAAAGATGCTCTGCAGTCATTTGCTGATGGGGTGAATGCTTTTATACGCGAGGCAAAAGAG
GAAAAGAAATTGCCGGTCGAGTTTACTATATTAGGCTATGAACCTGCTGAGTGGTCAATTGTTGATACGTTAACAATTGG
AAAGTATATGGCGTTTGATTTAGGCGGACATTGGCATGGACAGGCATTTCGATATTGGGCGCTGAAAAATCTACCGAAAG
AGCAAGCAAATGAGTTATTTCCTACATATCCGAAAGATGCCCCTAGATTGCTAGCTGAACTTGAGAATACAAATGTGAAT
GTCGTACAAAGTTTTGCAAAAACGATCATTCCACCAGAGTTTAATGGTAGTAATAACTGGGTTATAAGCGGTGAGAAGAG
TGCGTCTGGTAAGCCGATTTTAGCGGATGATCCTCATTTATCTCTTGCGACGCCTTCTATTTGGTATCAATCGAAACTTG
AGATGAAAGATTTGAATGTGAGTGGCGTTATTTTCGCTGGCGTACCAGGGGTTATATTAGGACACAATGACAAAATAGCA
TGGGGCGTTACGAATACAGGTCCTGATGTGCAAGATTTATATATTGAGAAGAGAAATCCTAATAATGAAAATGAATTTCT
GTATAACGATAAGTGGGAAAAAGCTACCGTTGTGGATGAATCTATTAAAGTAAAAGGCGGGAAAACAATTCCGTATAACG
TTACAGTTACGAGGCATGGCCCAGTCATTTCAGAGTTTGCGGATAAAGGGAAAGAGAAAACGAAAACAGTATTTGCTTTG
AAATGGACTGCTTTGGAGCCTTCCGCTGAATTAAAGGCTGTATTAAATATGAATAAGGCGAAAGACTGGAATGAGTTTGA
AACGGCACTGCAAGATTTTCATACACCAACTCAAAACTTTGTATTTGCATCAAATGACGGCACAATTGCTTATAAAGCAA
ATGGAAATATACCAGTGCGTAAAAAAGGTGATGGTAGTTTACCTGTTCCAGGATGGACAGATGAATATGAATGGGAAGGG
TATATCCCGTATGATCAGCTACCAAAAGTAATCAATCCAAAACAAGGGTTTATTTCAACTGCGAATAATAAAATTGTAGA
TGATAATTATCCGTATCATATTAGTAATACGTGGGCGCAGCCATATAGGCAAATGCGTATTCAAGAGTTTTTACAAGAGA
AGGAAAAATATACAGTGAAAGATTTAGAAGAGTTACAGATGGATCAAAAAAATTTATACGGGAAAGAGTTTACTCCTATA
TTTTTAAAAGAGTTAAATAAAGCGCCTTTACATGAAGTAGAGAAAGAAGGCGTAAAACAATTAACGAAGTGGAATTTTTA
CGATAGTAAAGATGACGCGGCACCGTTAATATTCCATTTATTAATGAAGGAGATTTCAAATACGTTATTTTCAAAAGAAA
TTCCGAAAGATGTGATGGAGTTATTTGAAGGGAAGTCACAAGTTGTGGATGAATTGATTCGAAAAGAAGTAGCAGGAGAA
AAGAGCGCTTGGTTTACGAAGTACGGAGGATTCACAAAAGTTGTGCATACATCGTACGAAAATGTAATGAAGAAATTACA
GAAGGAATATGGACCAGATGTTACGGAGTGGAAGTGGGGCGATTATCACCAACTTGCTTTTACACACCCAATTTCAAAAT
CATCTAGTATGTTAGCGCTACTTGCGTTTAATCGTGAGAAACCAGTTCCAATTGGCGGAAGTCAAGTTACCGTTCAAGCA
GCGAGTTACGGCGATAACGGTATTGTCAATCACGGAGCGTCTTGGAGATTCGTCATTGATACGAAAGATATGTCAAACGG
TTATCATATTGTAGGGCCAGGACAATCAGGGCATTTTAGAAGTGATTGGTATCATGATCAAATAGATGATTGGGTAAATG
GCACGTATCATACGACTACATTGAATACGGAGGGGATAGAGGGGAAGGTGTTAAATTTAGAGCCGAAGTGA

Upstream 100 bases:

>100_bases
GTCTGTTTACATGACCCATAACATGAGAAAAGAAGGATTTTTCCTATTCAAAAAGGTTCTTTCAAAATAGAAGCGAATAG
TTTGAGAAAGGAGGGGTTAT

Downstream 100 bases:

>100_bases
TAGAGTGTTTTTGTTTGTGGAGGGGACTAGTAATAATCTTTTTGATAATGAAAGCTTATCATTTAGAACATAACCTAGTT
CTTAAATAATTTTAACAGCC

Product: penicillin acylase II

Products: NA

Alternate protein names: Cephalosporin acylase II; Penicillin acylase II; Penicillin amidase II; Penicillin acylase II small subunit; Penicillin acylase II large subunit [H]

Number of amino acids: Translated: 796; Mature: 796

Protein sequence:

>796_residues
MEVVIKKKRTRGKKIFIWSSSIVLLLVICTAIFLNIYTLKSVPKIDGTIKLEDLQRAVTVKRDSKGVPHIKAENAHDLYF
SQGYVQAQDRLFQMDLSRRQASGMLSEVVGEAAVDRDKLFRTLGLRRAAEASVSQYDGEAKDALQSFADGVNAFIREAKE
EKKLPVEFTILGYEPAEWSIVDTLTIGKYMAFDLGGHWHGQAFRYWALKNLPKEQANELFPTYPKDAPRLLAELENTNVN
VVQSFAKTIIPPEFNGSNNWVISGEKSASGKPILADDPHLSLATPSIWYQSKLEMKDLNVSGVIFAGVPGVILGHNDKIA
WGVTNTGPDVQDLYIEKRNPNNENEFLYNDKWEKATVVDESIKVKGGKTIPYNVTVTRHGPVISEFADKGKEKTKTVFAL
KWTALEPSAELKAVLNMNKAKDWNEFETALQDFHTPTQNFVFASNDGTIAYKANGNIPVRKKGDGSLPVPGWTDEYEWEG
YIPYDQLPKVINPKQGFISTANNKIVDDNYPYHISNTWAQPYRQMRIQEFLQEKEKYTVKDLEELQMDQKNLYGKEFTPI
FLKELNKAPLHEVEKEGVKQLTKWNFYDSKDDAAPLIFHLLMKEISNTLFSKEIPKDVMELFEGKSQVVDELIRKEVAGE
KSAWFTKYGGFTKVVHTSYENVMKKLQKEYGPDVTEWKWGDYHQLAFTHPISKSSSMLALLAFNREKPVPIGGSQVTVQA
ASYGDNGIVNHGASWRFVIDTKDMSNGYHIVGPGQSGHFRSDWYHDQIDDWVNGTYHTTTLNTEGIEGKVLNLEPK

Sequences:

>Translated_796_residues
MEVVIKKKRTRGKKIFIWSSSIVLLLVICTAIFLNIYTLKSVPKIDGTIKLEDLQRAVTVKRDSKGVPHIKAENAHDLYF
SQGYVQAQDRLFQMDLSRRQASGMLSEVVGEAAVDRDKLFRTLGLRRAAEASVSQYDGEAKDALQSFADGVNAFIREAKE
EKKLPVEFTILGYEPAEWSIVDTLTIGKYMAFDLGGHWHGQAFRYWALKNLPKEQANELFPTYPKDAPRLLAELENTNVN
VVQSFAKTIIPPEFNGSNNWVISGEKSASGKPILADDPHLSLATPSIWYQSKLEMKDLNVSGVIFAGVPGVILGHNDKIA
WGVTNTGPDVQDLYIEKRNPNNENEFLYNDKWEKATVVDESIKVKGGKTIPYNVTVTRHGPVISEFADKGKEKTKTVFAL
KWTALEPSAELKAVLNMNKAKDWNEFETALQDFHTPTQNFVFASNDGTIAYKANGNIPVRKKGDGSLPVPGWTDEYEWEG
YIPYDQLPKVINPKQGFISTANNKIVDDNYPYHISNTWAQPYRQMRIQEFLQEKEKYTVKDLEELQMDQKNLYGKEFTPI
FLKELNKAPLHEVEKEGVKQLTKWNFYDSKDDAAPLIFHLLMKEISNTLFSKEIPKDVMELFEGKSQVVDELIRKEVAGE
KSAWFTKYGGFTKVVHTSYENVMKKLQKEYGPDVTEWKWGDYHQLAFTHPISKSSSMLALLAFNREKPVPIGGSQVTVQA
ASYGDNGIVNHGASWRFVIDTKDMSNGYHIVGPGQSGHFRSDWYHDQIDDWVNGTYHTTTLNTEGIEGKVLNLEPK
>Mature_796_residues
MEVVIKKKRTRGKKIFIWSSSIVLLLVICTAIFLNIYTLKSVPKIDGTIKLEDLQRAVTVKRDSKGVPHIKAENAHDLYF
SQGYVQAQDRLFQMDLSRRQASGMLSEVVGEAAVDRDKLFRTLGLRRAAEASVSQYDGEAKDALQSFADGVNAFIREAKE
EKKLPVEFTILGYEPAEWSIVDTLTIGKYMAFDLGGHWHGQAFRYWALKNLPKEQANELFPTYPKDAPRLLAELENTNVN
VVQSFAKTIIPPEFNGSNNWVISGEKSASGKPILADDPHLSLATPSIWYQSKLEMKDLNVSGVIFAGVPGVILGHNDKIA
WGVTNTGPDVQDLYIEKRNPNNENEFLYNDKWEKATVVDESIKVKGGKTIPYNVTVTRHGPVISEFADKGKEKTKTVFAL
KWTALEPSAELKAVLNMNKAKDWNEFETALQDFHTPTQNFVFASNDGTIAYKANGNIPVRKKGDGSLPVPGWTDEYEWEG
YIPYDQLPKVINPKQGFISTANNKIVDDNYPYHISNTWAQPYRQMRIQEFLQEKEKYTVKDLEELQMDQKNLYGKEFTPI
FLKELNKAPLHEVEKEGVKQLTKWNFYDSKDDAAPLIFHLLMKEISNTLFSKEIPKDVMELFEGKSQVVDELIRKEVAGE
KSAWFTKYGGFTKVVHTSYENVMKKLQKEYGPDVTEWKWGDYHQLAFTHPISKSSSMLALLAFNREKPVPIGGSQVTVQA
ASYGDNGIVNHGASWRFVIDTKDMSNGYHIVGPGQSGHFRSDWYHDQIDDWVNGTYHTTTLNTEGIEGKVLNLEPK

Specific function: Unknown

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.11 [H]

Molecular weight: Translated: 90149; Mature: 90149

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVVIKKKRTRGKKIFIWSSSIVLLLVICTAIFLNIYTLKSVPKIDGTIKLEDLQRAVTV
CCEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHE
KRDSKGVPHIKAENAHDLYFSQGYVQAQDRLFQMDLSRRQASGMLSEVVGEAAVDRDKLF
ECCCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RTLGLRRAAEASVSQYDGEAKDALQSFADGVNAFIREAKEEKKLPVEFTILGYEPAEWSI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEE
VDTLTIGKYMAFDLGGHWHGQAFRYWALKNLPKEQANELFPTYPKDAPRLLAELENTNVN
EEEEHHCCEEEEECCCCCCCCCEEEHHHHCCCHHHHHCCCCCCCCHHHHHHHHHCCCCHH
VVQSFAKTIIPPEFNGSNNWVISGEKSASGKPILADDPHLSLATPSIWYQSKLEMKDLNV
HHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCEECCCCCCEECCCCHHHCCCCEEECCCC
SGVIFAGVPGVILGHNDKIAWGVTNTGPDVQDLYIEKRNPNNENEFLYNDKWEKATVVDE
CEEEEECCCEEEEECCCEEEEECCCCCCCHHHEEEECCCCCCCCCEEECCCCCEEEEECC
SIKVKGGKTIPYNVTVTRHGPVISEFADKGKEKTKTVFALKWTALEPSAELKAVLNMNKA
CEEECCCCCCCEEEEEECCCCHHHHHHHCCCHHCCEEEEEEEEECCCCHHHHHHHCCCCC
KDWNEFETALQDFHTPTQNFVFASNDGTIAYKANGNIPVRKKGDGSLPVPGWTDEYEWEG
CCHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCC
YIPYDQLPKVINPKQGFISTANNKIVDDNYPYHISNTWAQPYRQMRIQEFLQEKEKYTVK
CCCHHHCCCCCCCCCCCEECCCCCEECCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCHH
DLEELQMDQKNLYGKEFTPIFLKELNKAPLHEVEKEGVKQLTKWNFYDSKDDAAPLIFHL
HHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LMKEISNTLFSKEIPKDVMELFEGKSQVVDELIRKEVAGEKSAWFTKYGGFTKVVHTSYE
HHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHH
NVMKKLQKEYGPDVTEWKWGDYHQLAFTHPISKSSSMLALLAFNREKPVPIGGSQVTVQA
HHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEEEEEE
ASYGDNGIVNHGASWRFVIDTKDMSNGYHIVGPGQSGHFRSDWYHDQIDDWVNGTYHTTT
ECCCCCCCEECCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCEEEEE
LNTEGIEGKVLNLEPK
ECCCCCCCEEEECCCC
>Mature Secondary Structure
MEVVIKKKRTRGKKIFIWSSSIVLLLVICTAIFLNIYTLKSVPKIDGTIKLEDLQRAVTV
CCEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHE
KRDSKGVPHIKAENAHDLYFSQGYVQAQDRLFQMDLSRRQASGMLSEVVGEAAVDRDKLF
ECCCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RTLGLRRAAEASVSQYDGEAKDALQSFADGVNAFIREAKEEKKLPVEFTILGYEPAEWSI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEE
VDTLTIGKYMAFDLGGHWHGQAFRYWALKNLPKEQANELFPTYPKDAPRLLAELENTNVN
EEEEHHCCEEEEECCCCCCCCCEEEHHHHCCCHHHHHCCCCCCCCHHHHHHHHHCCCCHH
VVQSFAKTIIPPEFNGSNNWVISGEKSASGKPILADDPHLSLATPSIWYQSKLEMKDLNV
HHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCEECCCCCCEECCCCHHHCCCCEEECCCC
SGVIFAGVPGVILGHNDKIAWGVTNTGPDVQDLYIEKRNPNNENEFLYNDKWEKATVVDE
CEEEEECCCEEEEECCCEEEEECCCCCCCHHHEEEECCCCCCCCCEEECCCCCEEEEECC
SIKVKGGKTIPYNVTVTRHGPVISEFADKGKEKTKTVFALKWTALEPSAELKAVLNMNKA
CEEECCCCCCCEEEEEECCCCHHHHHHHCCCHHCCEEEEEEEEECCCCHHHHHHHCCCCC
KDWNEFETALQDFHTPTQNFVFASNDGTIAYKANGNIPVRKKGDGSLPVPGWTDEYEWEG
CCHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCC
YIPYDQLPKVINPKQGFISTANNKIVDDNYPYHISNTWAQPYRQMRIQEFLQEKEKYTVK
CCCHHHCCCCCCCCCCCEECCCCCEECCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCHH
DLEELQMDQKNLYGKEFTPIFLKELNKAPLHEVEKEGVKQLTKWNFYDSKDDAAPLIFHL
HHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LMKEISNTLFSKEIPKDVMELFEGKSQVVDELIRKEVAGEKSAWFTKYGGFTKVVHTSYE
HHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHH
NVMKKLQKEYGPDVTEWKWGDYHQLAFTHPISKSSSMLALLAFNREKPVPIGGSQVTVQA
HHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEEEEEE
ASYGDNGIVNHGASWRFVIDTKDMSNGYHIVGPGQSGHFRSDWYHDQIDDWVNGTYHTTT
ECCCCCCCEECCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCEEEEE
LNTEGIEGKVLNLEPK
ECCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3680178 [H]