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The map label for this gene is flp [H]

Identifier: 49478085

GI number: 49478085

Start: 3078863

End: 3080404

Strand: Reverse

Name: flp [H]

Synonym: BT9727_2997

Alternate gene names: 49478085

Gene position: 3080404-3078863 (Counterclockwise)

Preceding gene: 49478086

Following gene: 49478084

Centisome position: 58.81

GC content: 35.93

Gene sequence:

>1542_bases
ATGAAGAATAGACAAAAAGCATCGATAATATGCAAAAGCATTTTATGTTTAATCATTTGCATATTGATTACGAATGGAGC
ATGGTTTACAAATGTGGTGAGGGCAGAATCGGGCATGCTGACTGATAGGAGTATAGAGGATTTCAAAAAAAAGCTGGATG
AACAGGTACCAAAATGGCAGGGGGATTATGAGGTACCGGGGGTTGCAATAGGAATTGTGCATGAGGGGCGTATTGCTTAT
ACACTTAACTACGGTTATGTAGATAAAATGACAAAAAAAGCGGTGAGTGATGATACTTTGTTTCAGGCTGGTTCCATATC
TAAAAGTCTTACAGCGTGGGGAATCTTGCATCTTGTAGATGAAGGGCGTTTATCACTAGATGATCCCGTTGGAAAATATC
TGACCAAATGGAAATTACCTAATTCAGAGTTTAATAATAATGAAATCACGATCAGAAGATTATTAAGTCATACAGCAGGG
CTGTCTGCACATAAAGGATACCTTGGGGTTGCACCAGGGAAACATCTTGACTCTATTGAGGAGTCTCTGTCTGGAAAAGG
ATGGCTTAATGAACCAGTGGAGGTTACCAATAAACCAGGTTCAGAAACAATTTACTCTGGTGGCGGATATACAATTTTAC
AACTTGTAATTGAAGAAGTTACCGGAATACCGTTTGATCGTTATATGGAAGAACAAATCATGAAGCCTTTAGGAATGAAA
TCTAGTTCATTTTTACAACGTCCTGAAAACCATAACCTTTCAAAAGCTTATGGATATTTTGGAGAGGAGCTCCCTAGTTA
CCAATTTACCGAACAGGCTGCTGCAGGTCTTAAGACAAATGTTATCGATATGATGACATTGATACTTGCAAGCATGGATG
CAAATAATAAAGGGAATGGTGTCATCAAAAGTGAACGTGTTGAGGAAATGCAAAAGCCAGTATTAGGGGAGAACGGTTTA
GGTATATTTGAAAAAAAACTATCTAATCAATGGAAATTACTTTATCATTCTGGTGACAATCGAGGCTGGCATTCTTTTTA
TGGTTTTATTCCTAATACAAAGGATGGATTGGTAATCCTTACAAATGGTGAAGGTGGTATAGACTTACGACAGGATATTT
ACCACGCATGGATTGAATATGAAACGGGAAAATTACCTGAAAGTTACTTTTCTCTAGCAGAGCAGAGAAAAACTAACTTC
ATTACATCAATTGTTATTGGCGCCGCGCTTGGTATATATTTGCTACTATTTGTGATTAGATTGTACAAAGGTAGAAGAAC
TTTTATTTTTAAGCAAGAGAAGAAATCTTACATCGGATTAGTAGTTAGGACATTTTTACTTGTTGTTACTGCTGTTCTCA
TTTTTTGTGCTGCTTATTTGTGGAGAGTTTTCAGCTTGAATTCCGGTAATACAATAAATTTTATTCTAATAATGGCATGG
ATTATAACGCTATTAATTAGTGGATTTTTCCCGGAAATTAAAAGTAATAAAAAACAACGTATGAAACGAAAAAAATTAAC
ATCAAAATTTACATGTATGTAA

Upstream 100 bases:

>100_bases
CAATTTTGTAAGGTTAAGTAATAAAAATCGATAGAACGGGATATTGGAATGGGATACTCTGATTGATGGGTAGAATATTC
TGGAAAAAGGGGGGGAACAA

Downstream 100 bases:

>100_bases
TGTTAAAGGCTAGAAAGCTAGATTGGCGTGAATCACTAATTGTGGAGTGCAAAAAACAACAAAATCTTTTAAAAAACACT
TAATTTTTTACTCCATCTAT

Product: beta-lactamase

Products: NA

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MKNRQKASIICKSILCLIICILITNGAWFTNVVRAESGMLTDRSIEDFKKKLDEQVPKWQGDYEVPGVAIGIVHEGRIAY
TLNYGYVDKMTKKAVSDDTLFQAGSISKSLTAWGILHLVDEGRLSLDDPVGKYLTKWKLPNSEFNNNEITIRRLLSHTAG
LSAHKGYLGVAPGKHLDSIEESLSGKGWLNEPVEVTNKPGSETIYSGGGYTILQLVIEEVTGIPFDRYMEEQIMKPLGMK
SSSFLQRPENHNLSKAYGYFGEELPSYQFTEQAAAGLKTNVIDMMTLILASMDANNKGNGVIKSERVEEMQKPVLGENGL
GIFEKKLSNQWKLLYHSGDNRGWHSFYGFIPNTKDGLVILTNGEGGIDLRQDIYHAWIEYETGKLPESYFSLAEQRKTNF
ITSIVIGAALGIYLLLFVIRLYKGRRTFIFKQEKKSYIGLVVRTFLLVVTAVLIFCAAYLWRVFSLNSGNTINFILIMAW
IITLLISGFFPEIKSNKKQRMKRKKLTSKFTCM

Sequences:

>Translated_513_residues
MKNRQKASIICKSILCLIICILITNGAWFTNVVRAESGMLTDRSIEDFKKKLDEQVPKWQGDYEVPGVAIGIVHEGRIAY
TLNYGYVDKMTKKAVSDDTLFQAGSISKSLTAWGILHLVDEGRLSLDDPVGKYLTKWKLPNSEFNNNEITIRRLLSHTAG
LSAHKGYLGVAPGKHLDSIEESLSGKGWLNEPVEVTNKPGSETIYSGGGYTILQLVIEEVTGIPFDRYMEEQIMKPLGMK
SSSFLQRPENHNLSKAYGYFGEELPSYQFTEQAAAGLKTNVIDMMTLILASMDANNKGNGVIKSERVEEMQKPVLGENGL
GIFEKKLSNQWKLLYHSGDNRGWHSFYGFIPNTKDGLVILTNGEGGIDLRQDIYHAWIEYETGKLPESYFSLAEQRKTNF
ITSIVIGAALGIYLLLFVIRLYKGRRTFIFKQEKKSYIGLVVRTFLLVVTAVLIFCAAYLWRVFSLNSGNTINFILIMAW
IITLLISGFFPEIKSNKKQRMKRKKLTSKFTCM
>Mature_513_residues
MKNRQKASIICKSILCLIICILITNGAWFTNVVRAESGMLTDRSIEDFKKKLDEQVPKWQGDYEVPGVAIGIVHEGRIAY
TLNYGYVDKMTKKAVSDDTLFQAGSISKSLTAWGILHLVDEGRLSLDDPVGKYLTKWKLPNSEFNNNEITIRRLLSHTAG
LSAHKGYLGVAPGKHLDSIEESLSGKGWLNEPVEVTNKPGSETIYSGGGYTILQLVIEEVTGIPFDRYMEEQIMKPLGMK
SSSFLQRPENHNLSKAYGYFGEELPSYQFTEQAAAGLKTNVIDMMTLILASMDANNKGNGVIKSERVEEMQKPVLGENGL
GIFEKKLSNQWKLLYHSGDNRGWHSFYGFIPNTKDGLVILTNGEGGIDLRQDIYHAWIEYETGKLPESYFSLAEQRKTNF
ITSIVIGAALGIYLLLFVIRLYKGRRTFIFKQEKKSYIGLVVRTFLLVVTAVLIFCAAYLWRVFSLNSGNTINFILIMAW
IITLLISGFFPEIKSNKKQRMKRKKLTSKFTCM

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082101, Length=229, Percent_Identity=30.1310043668122, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790593, Length=245, Percent_Identity=25.3061224489796, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115533026, Length=383, Percent_Identity=26.1096605744125, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17550934, Length=200, Percent_Identity=31, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 57836; Mature: 57836

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRQKASIICKSILCLIICILITNGAWFTNVVRAESGMLTDRSIEDFKKKLDEQVPKWQ
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCC
GDYEVPGVAIGIVHEGRIAYTLNYGYVDKMTKKAVSDDTLFQAGSISKSLTAWGILHLVD
CCCCCCCEEEEEEECCEEEEEEECCHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHC
EGRLSLDDPVGKYLTKWKLPNSEFNNNEITIRRLLSHTAGLSAHKGYLGVAPGKHLDSIE
CCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHH
ESLSGKGWLNEPVEVTNKPGSETIYSGGGYTILQLVIEEVTGIPFDRYMEEQIMKPLGMK
HHHCCCCCCCCCHHHCCCCCCCCEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
SSSFLQRPENHNLSKAYGYFGEELPSYQFTEQAAAGLKTNVIDMMTLILASMDANNKGNG
CHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
VIKSERVEEMQKPVLGENGLGIFEKKLSNQWKLLYHSGDNRGWHSFYGFIPNTKDGLVIL
CCCHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCHHHHCCCCCCCCCCEEEE
TNGEGGIDLRQDIYHAWIEYETGKLPESYFSLAEQRKTNFITSIVIGAALGIYLLLFVIR
ECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYKGRRTFIFKQEKKSYIGLVVRTFLLVVTAVLIFCAAYLWRVFSLNSGNTINFILIMAW
HHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IITLLISGFFPEIKSNKKQRMKRKKLTSKFTCM
HHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNRQKASIICKSILCLIICILITNGAWFTNVVRAESGMLTDRSIEDFKKKLDEQVPKWQ
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCC
GDYEVPGVAIGIVHEGRIAYTLNYGYVDKMTKKAVSDDTLFQAGSISKSLTAWGILHLVD
CCCCCCCEEEEEEECCEEEEEEECCHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHC
EGRLSLDDPVGKYLTKWKLPNSEFNNNEITIRRLLSHTAGLSAHKGYLGVAPGKHLDSIE
CCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHH
ESLSGKGWLNEPVEVTNKPGSETIYSGGGYTILQLVIEEVTGIPFDRYMEEQIMKPLGMK
HHHCCCCCCCCCHHHCCCCCCCCEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
SSSFLQRPENHNLSKAYGYFGEELPSYQFTEQAAAGLKTNVIDMMTLILASMDANNKGNG
CHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
VIKSERVEEMQKPVLGENGLGIFEKKLSNQWKLLYHSGDNRGWHSFYGFIPNTKDGLVIL
CCCHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCHHHHCCCCCCCCCCEEEE
TNGEGGIDLRQDIYHAWIEYETGKLPESYFSLAEQRKTNFITSIVIGAALGIYLLLFVIR
ECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYKGRRTFIFKQEKKSYIGLVVRTFLLVVTAVLIFCAAYLWRVFSLNSGNTINFILIMAW
HHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IITLLISGFFPEIKSNKKQRMKRKKLTSKFTCM
HHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA