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The map label for this gene is ccdA

Identifier: 49478036

GI number: 49478036

Start: 3501950

End: 3502657

Strand: Reverse

Name: ccdA

Synonym: BT9727_3417

Alternate gene names: 49478036

Gene position: 3502657-3501950 (Counterclockwise)

Preceding gene: 49478318

Following gene: 49478957

Centisome position: 66.87

GC content: 33.9

Gene sequence:

>708_bases
ATGCAAGATATTAGTATTTTTTTAGCGTTTGGCGCCGGTTTTTTATCATTTATTTCCCCATGTTGCTTGCCGCTTTATCC
GGCATTTCTATCATATATAACAGGTATGTCGGTTTCTGAGCTGAAAGAAGAAAATGCAATGCTTCGCAAAAGAAGTATGA
TACATACAGCGTTTTTCTTACTTGGATTTTCAATTATATTTATTGCAATTGGATTTGGTACAAGTTTTATTGGAGGCATC
TTTACAAATTATAAAGATTTAATTAGACAGTTAGGTGGTATATTTATCATCGTGTTCGGTCTTATTATTGTCGGTGTGTT
TAAGCCGAAGTTTTTAATGCAAGATCGTAAATTCACGTTTAAAAATCGTCCGAGTGGTTATTTTGGATCTGTTCTAATTG
GGTTGGCATTTGCGGCAGGATGGACACCTTGTACAGGACCTATTTTAGTATCGGTTATTGGATTAGCAGCAACAAATCCA
GAATCAGCAATGATTTATATGATTGCATACATACTTGGATTTGCTATCCCGTTCTTCGTACTATCATTCTTTATTACGAA
AATGTCTTGGATTAAAAGAAACAGTATGAAGTTCATGAAAATCGGGGGATACATTATGATTATCATGGGTATCTTCTTAT
ACTTTAACTGGATGACAAAAATTATCGTATATTTCTCAAGTTTATTTGGTGGTTTTACGGGTTTTTAG

Upstream 100 bases:

>100_bases
GGTGGTTTTTCTTATTATCACGTTGGAAAAGTGATTTCACGAATTGTTCATAGTATTTTTATGTGTTTTTGCTACAATAT
GTAAGGAGAGGAGTGGAACA

Downstream 100 bases:

>100_bases
TATTATTCTGTGAAAATGTTGGAAATACTAACGGAAAAGCATATAATGAAAGTATATTTTGCATATAGCCACAAAAAAGG
ATGAGAAAATATGAACATAG

Product: cytochrome c-type biogenesis protein (holocytochrome-c synthase)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFLLGFSIIFIAIGFGTSFIGGI
FTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTFKNRPSGYFGSVLIGLAFAAGWTPCTGPILVSVIGLAATNP
ESAMIYMIAYILGFAIPFFVLSFFITKMSWIKRNSMKFMKIGGYIMIIMGIFLYFNWMTKIIVYFSSLFGGFTGF

Sequences:

>Translated_235_residues
MQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFLLGFSIIFIAIGFGTSFIGGI
FTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTFKNRPSGYFGSVLIGLAFAAGWTPCTGPILVSVIGLAATNP
ESAMIYMIAYILGFAIPFFVLSFFITKMSWIKRNSMKFMKIGGYIMIIMGIFLYFNWMTKIIVYFSSLFGGFTGF
>Mature_235_residues
MQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFLLGFSIIFIAIGFGTSFIGGI
FTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTFKNRPSGYFGSVLIGLAFAAGWTPCTGPILVSVIGLAATNP
ESAMIYMIAYILGFAIPFFVLSFFITKMSWIKRNSMKFMKIGGYIMIIMGIFLYFNWMTKIIVYFSSLFGGFTGF

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 26291; Mature: 26291

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LGFSIIFIAIGFGTSFIGGIFTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCC
KNRPSGYFGSVLIGLAFAAGWTPCTGPILVSVIGLAATNPESAMIYMIAYILGFAIPFFV
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LSFFITKMSWIKRNSMKFMKIGGYIMIIMGIFLYFNWMTKIIVYFSSLFGGFTGF
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LGFSIIFIAIGFGTSFIGGIFTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCC
KNRPSGYFGSVLIGLAFAAGWTPCTGPILVSVIGLAATNPESAMIYMIAYILGFAIPFFV
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LSFFITKMSWIKRNSMKFMKIGGYIMIIMGIFLYFNWMTKIIVYFSSLFGGFTGF
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]