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The map label for this gene is cynT [H]

Identifier: 49476257

GI number: 49476257

Start: 1849227

End: 1849883

Strand: Reverse

Name: cynT [H]

Synonym: BH16050

Alternate gene names: 49476257

Gene position: 1849883-1849227 (Counterclockwise)

Preceding gene: 49476259

Following gene: 49476256

Centisome position: 95.8

GC content: 40.49

Gene sequence:

>657_bases
ATGACGCGTTTACCAGAAAGACTCTTAAGCGGTTACCGGTCTTTTATAAAAAATCATTTTTTTTATAAAACGGCACATTA
TCAGCAATTAGCAATAGAGGGGCAGAAGCCTGAAATTTTGGTCATTGCTTGTTGTGATTCGCGGGCAATACCAGAAACGA
TTTTTGATGCTAAACCAGGTGAAATTTTTACGCTGCGCAACGTGGCAAATTTGGTTCCTCCTTTTTCTCCTGATAATCAG
TATCATGCAACATCAGCAGCGATTGAATATGCTGTCCAATTGCTTGAGGTGAAGCATATTGTTGTTTTTGGTCATGCCCA
TTGTGGGGGGGTGAACACTGCTCTTGAGGGGACGTGCAAGTCTTTATCGTCAAATGATTTTATTGGTCAATGGATAAGTC
TTTTGATACCAGCAGCACAAACAATTATTGAAAACAAGTCGTTGACCCCTTCAGAGCAGCAGACCGCATTAGAGAAACTT
TCTATTCGTCATTCGTTGAAAAATTTAGAAACATTTCCCTGGATAAAGGCGCGTAAAGATCAGGGTATTTTGACGTTGCA
CGGGGTTTGGTTTGATATCTCAAGTGGTGAATTATGGAGTATGGAACAGGAAACAGGTCATTTTATGCGTGTTGAGGTGG
GGAATTTTGAGGAATAA

Upstream 100 bases:

>100_bases
GCTTTATGGAAATATTTTGCTCGATGAAAGGACATTTTTAGTGCTTTTGTATGTTAGTAGTCTGTTTTTTCAAAAGAGAT
AAAATGAAAGTGAATATCAA

Downstream 100 bases:

>100_bases
TGTCTGCTACCTTTTTGCTTCGTATAAAAGGTATTGTATGATAAATCTTGACAAAGTGTGGGTTTTATTGTTTGAAAGGG
CAAGCTTTCAGTGACAAAAT

Product: carbonic anhydrase protein

Products: NA

Alternate protein names: Carbonate dehydratase 1 [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTRLPERLLSGYRSFIKNHFFYKTAHYQQLAIEGQKPEILVIACCDSRAIPETIFDAKPGEIFTLRNVANLVPPFSPDNQ
YHATSAAIEYAVQLLEVKHIVVFGHAHCGGVNTALEGTCKSLSSNDFIGQWISLLIPAAQTIIENKSLTPSEQQTALEKL
SIRHSLKNLETFPWIKARKDQGILTLHGVWFDISSGELWSMEQETGHFMRVEVGNFEE

Sequences:

>Translated_218_residues
MTRLPERLLSGYRSFIKNHFFYKTAHYQQLAIEGQKPEILVIACCDSRAIPETIFDAKPGEIFTLRNVANLVPPFSPDNQ
YHATSAAIEYAVQLLEVKHIVVFGHAHCGGVNTALEGTCKSLSSNDFIGQWISLLIPAAQTIIENKSLTPSEQQTALEKL
SIRHSLKNLETFPWIKARKDQGILTLHGVWFDISSGELWSMEQETGHFMRVEVGNFEE
>Mature_217_residues
TRLPERLLSGYRSFIKNHFFYKTAHYQQLAIEGQKPEILVIACCDSRAIPETIFDAKPGEIFTLRNVANLVPPFSPDNQY
HATSAAIEYAVQLLEVKHIVVFGHAHCGGVNTALEGTCKSLSSNDFIGQWISLLIPAAQTIIENKSLTPSEQQTALEKLS
IRHSLKNLETFPWIKARKDQGILTLHGVWFDISSGELWSMEQETGHFMRVEVGNFEE

Specific function: Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to c

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=206, Percent_Identity=31.5533980582524, Blast_Score=113, Evalue=8e-27,
Organism=Escherichia coli, GI1786318, Length=184, Percent_Identity=32.6086956521739, Blast_Score=74, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI115532990, Length=246, Percent_Identity=23.9837398373984, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25147564, Length=208, Percent_Identity=23.0769230769231, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324292, Length=179, Percent_Identity=26.8156424581006, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24645213, Length=229, Percent_Identity=27.5109170305677, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24557; Mature: 24426

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLPERLLSGYRSFIKNHFFYKTAHYQQLAIEGQKPEILVIACCDSRAIPETIFDAKPG
CCCCHHHHHHHHHHHHHHHHEEEECCCEEEEECCCCCCEEEEEECCCCCCCHHHHCCCCC
EIFTLRNVANLVPPFSPDNQYHATSAAIEYAVQLLEVKHIVVFGHAHCGGVNTALEGTCK
CEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHH
SLSSNDFIGQWISLLIPAAQTIIENKSLTPSEQQTALEKLSIRHSLKNLETFPWIKARKD
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCC
QGILTLHGVWFDISSGELWSMEQETGHFMRVEVGNFEE
CCEEEEEEEEEECCCCCEEEEHHCCCCEEEEECCCCCC
>Mature Secondary Structure 
TRLPERLLSGYRSFIKNHFFYKTAHYQQLAIEGQKPEILVIACCDSRAIPETIFDAKPG
CCCHHHHHHHHHHHHHHHHEEEECCCEEEEECCCCCCEEEEEECCCCCCCHHHHCCCCC
EIFTLRNVANLVPPFSPDNQYHATSAAIEYAVQLLEVKHIVVFGHAHCGGVNTALEGTCK
CEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHH
SLSSNDFIGQWISLLIPAAQTIIENKSLTPSEQQTALEKLSIRHSLKNLETFPWIKARKD
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCC
QGILTLHGVWFDISSGELWSMEQETGHFMRVEVGNFEE
CCEEEEEEEEEECCCCCEEEEHHCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]