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The map label for this gene is uup [H]

Identifier: 49476172

GI number: 49476172

Start: 1741102

End: 1742964

Strand: Reverse

Name: uup [H]

Synonym: BH15170

Alternate gene names: 49476172

Gene position: 1742964-1741102 (Counterclockwise)

Preceding gene: 49476173

Following gene: 49476170

Centisome position: 90.26

GC content: 43.96

Gene sequence:

>1863_bases
ATGGTGGTGCCGCTTTTGCGGCTTGACCGCATTTGCCTAACCTTTGGGAAAACGCCTTTGTTCAACCAAGCTTGTTTAGC
AGTTGAACAAGGCGCGCGTATTGCCCTTGTGGGACGTAATGGGTGTGGAAAGTCAACGCTGTTAAAAATTGCCGCTGGAA
TAATAGAGCCAAACGAGGGGGAAATTTTTCGCCACCCTCGGGCAACACTCCGTTATCTCTCACAAAATCCTGATTGTTCA
GGATTTGAAGATGTTCACGCCTTTGTAGAAGCAGGGCTCGATCATGTACCTGATGCACAGTGGATCAATACCCTTTTAGC
AAATCTTGGTTTTTCAGGAACCGAAAAATTGGCAAACCTTTCTGGGGGTGAAAGGCGGCGCGTTTCATTATTACAGGCCA
TAGCTGCAAAACCCGATATCCTTCTCTTAGATGAACCAACCAATCATCTCGATTTACCAACCATTGAATGGCTTGAAGGT
ACGTTATTTTCTTTGCGTTCAGCGCTTGTGGTGATTTCGCATGATCGGCGATTTTTAGAAAATGTCACTCGTTCAACGGT
ATGGCTTGATCGGGGGATTACTAAAAGACTCGAAAAGCGTTTTTCAGAGTTTGAAAATTGGCGTGATAAAGCGCTTGAAG
AGGAAGCTCTCGAACAACACAAATTAAGGCGACAGATTGCTCGTGAAGAACAATGGTTGCGCTATGGGGTAACAGCACGG
CGTAAACGAAATGTACGTCGTCTGGGTGCTTTAAAAGAACTGCGACAGCTTCATCAAACCTATAAAGGACCATCTGGAAG
TGCGCTTTTGACTGTTGCTAAAAGCCATGATTCTGGTCAATTGGTGCTGGAAGCAAAGCGCATTTCAAAGTCTTATGGTG
AGCGTGTTATTGTAAAAGATTTCTCTTTGCGCGTTCAGCGTGGTGATCGAATCGGTCTAGTTGGTCCCAACGGTATTGGA
AAGACTACGTTGCTGTCTGTTCTGATTGGGCAGGAAGCGGCTGATAGTGGAACGGTGAAGCATGGATATAATATCTCCAT
GGCGTTTCTTGATCAACAGCGCATTTTAAATGAAGAGGAAACATTAGCACATTATCTTACGGGGGGGAGAGGTGATACTC
TTGTGATCAATGGGCAAGAACGCCATGTGGTGTCTTATATGAAAGACTTTTTGTTTTTGCCCGAACAAGCACGTACACCA
CTTAAAGAATTTTCAGGTGGAGAAAGAGCCCGCCTTATGCTTGCTCGACTTCTTTCGCGCCCAGCAAATTTTTTGATTCT
TGATGAACCAACCAATGATTTGGATATGGAAACGTTGGACTTGTTGCAAGAATTTATTGCCGATTTTGCTGGAACTGTGT
TGTTGGTCAGCCATGATAGGGACTTTTTAGATCGCACTGTGACTCATATGTTGGCACCCCAAGGAGATGGACACTGGATT
TTGTATGCTGGCGGTTATAGTGATATGATAGCGCAAAACAAGCACGCTGCATTGTTAGGGTGCAAAGAGGGAGCAGTATC
ACAGGGTAAAGCCCTTTCAAATCCTCGTGTATTGGAGAATAAAAACTCCAATGCGTCAACAAATCGTGCCTCTATGGAGC
CGGAGAAAATAAAACCGCGTAAGCTGTCTTATAAGCAGGTTTATGCACTGGAGAAATTGCCTGAACAAATCGCTGTTTTG
CAAGACGAAATCAAAAAAATTGAACAAGAACTTTTTGACCCAGCACTGTATTGCAATGATAAAGAGCGTTTCGAGCGTCT
TTCTATAAAGCTTCAAGAAAAGCAAAAGCTTTGTGCGGGGAAAGAAGAAGAATGGTTAGAACTTGAACTTTTACGCGAAG
ATATAGAGGGTGTGAAGTCATAA

Upstream 100 bases:

>100_bases
CTGCGCCTTGTGCTCAAAAAGTGCAGACACCACAATTGTGTACTTACCGTGATGGAAGAGGTGTTATGTATCAAGCACCT
TGTCCACAACGCGTTCGTTA

Downstream 100 bases:

>100_bases
AAAAACGCGTTCATGTTAACCTTTTTTATAGATGTGGATAATCGCTTCTCTTTCATTTCCTATCTGTTTTTTGCACAATT
CTTTATGATGTAAGCGCATG

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 620

Protein sequence:

>620_residues
MVVPLLRLDRICLTFGKTPLFNQACLAVEQGARIALVGRNGCGKSTLLKIAAGIIEPNEGEIFRHPRATLRYLSQNPDCS
GFEDVHAFVEAGLDHVPDAQWINTLLANLGFSGTEKLANLSGGERRRVSLLQAIAAKPDILLLDEPTNHLDLPTIEWLEG
TLFSLRSALVVISHDRRFLENVTRSTVWLDRGITKRLEKRFSEFENWRDKALEEEALEQHKLRRQIAREEQWLRYGVTAR
RKRNVRRLGALKELRQLHQTYKGPSGSALLTVAKSHDSGQLVLEAKRISKSYGERVIVKDFSLRVQRGDRIGLVGPNGIG
KTTLLSVLIGQEAADSGTVKHGYNISMAFLDQQRILNEEETLAHYLTGGRGDTLVINGQERHVVSYMKDFLFLPEQARTP
LKEFSGGERARLMLARLLSRPANFLILDEPTNDLDMETLDLLQEFIADFAGTVLLVSHDRDFLDRTVTHMLAPQGDGHWI
LYAGGYSDMIAQNKHAALLGCKEGAVSQGKALSNPRVLENKNSNASTNRASMEPEKIKPRKLSYKQVYALEKLPEQIAVL
QDEIKKIEQELFDPALYCNDKERFERLSIKLQEKQKLCAGKEEEWLELELLREDIEGVKS

Sequences:

>Translated_620_residues
MVVPLLRLDRICLTFGKTPLFNQACLAVEQGARIALVGRNGCGKSTLLKIAAGIIEPNEGEIFRHPRATLRYLSQNPDCS
GFEDVHAFVEAGLDHVPDAQWINTLLANLGFSGTEKLANLSGGERRRVSLLQAIAAKPDILLLDEPTNHLDLPTIEWLEG
TLFSLRSALVVISHDRRFLENVTRSTVWLDRGITKRLEKRFSEFENWRDKALEEEALEQHKLRRQIAREEQWLRYGVTAR
RKRNVRRLGALKELRQLHQTYKGPSGSALLTVAKSHDSGQLVLEAKRISKSYGERVIVKDFSLRVQRGDRIGLVGPNGIG
KTTLLSVLIGQEAADSGTVKHGYNISMAFLDQQRILNEEETLAHYLTGGRGDTLVINGQERHVVSYMKDFLFLPEQARTP
LKEFSGGERARLMLARLLSRPANFLILDEPTNDLDMETLDLLQEFIADFAGTVLLVSHDRDFLDRTVTHMLAPQGDGHWI
LYAGGYSDMIAQNKHAALLGCKEGAVSQGKALSNPRVLENKNSNASTNRASMEPEKIKPRKLSYKQVYALEKLPEQIAVL
QDEIKKIEQELFDPALYCNDKERFERLSIKLQEKQKLCAGKEEEWLELELLREDIEGVKS
>Mature_620_residues
MVVPLLRLDRICLTFGKTPLFNQACLAVEQGARIALVGRNGCGKSTLLKIAAGIIEPNEGEIFRHPRATLRYLSQNPDCS
GFEDVHAFVEAGLDHVPDAQWINTLLANLGFSGTEKLANLSGGERRRVSLLQAIAAKPDILLLDEPTNHLDLPTIEWLEG
TLFSLRSALVVISHDRRFLENVTRSTVWLDRGITKRLEKRFSEFENWRDKALEEEALEQHKLRRQIAREEQWLRYGVTAR
RKRNVRRLGALKELRQLHQTYKGPSGSALLTVAKSHDSGQLVLEAKRISKSYGERVIVKDFSLRVQRGDRIGLVGPNGIG
KTTLLSVLIGQEAADSGTVKHGYNISMAFLDQQRILNEEETLAHYLTGGRGDTLVINGQERHVVSYMKDFLFLPEQARTP
LKEFSGGERARLMLARLLSRPANFLILDEPTNDLDMETLDLLQEFIADFAGTVLLVSHDRDFLDRTVTHMLAPQGDGHWI
LYAGGYSDMIAQNKHAALLGCKEGAVSQGKALSNPRVLENKNSNASTNRASMEPEKIKPRKLSYKQVYALEKLPEQIAVL
QDEIKKIEQELFDPALYCNDKERFERLSIKLQEKQKLCAGKEEEWLELELLREDIEGVKS

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=541, Percent_Identity=28.6506469500924, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI69354671, Length=512, Percent_Identity=29.296875, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI10947135, Length=512, Percent_Identity=29.296875, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI10947137, Length=500, Percent_Identity=28, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI27881506, Length=500, Percent_Identity=28, Blast_Score=137, Evalue=3e-32,
Organism=Escherichia coli, GI1787182, Length=650, Percent_Identity=36.1538461538462, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI2367384, Length=516, Percent_Identity=35.4651162790698, Blast_Score=289, Evalue=4e-79,
Organism=Escherichia coli, GI1787041, Length=533, Percent_Identity=28.3302063789869, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1789751, Length=641, Percent_Identity=28.5491419656786, Blast_Score=206, Evalue=5e-54,
Organism=Escherichia coli, GI1788165, Length=181, Percent_Identity=33.7016574585635, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1786563, Length=212, Percent_Identity=28.7735849056604, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081709, Length=163, Percent_Identity=31.2883435582822, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081782, Length=468, Percent_Identity=25.2136752136752, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1788506, Length=514, Percent_Identity=23.7354085603113, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87081791, Length=202, Percent_Identity=28.2178217821782, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786703, Length=178, Percent_Identity=34.2696629213483, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786698, Length=167, Percent_Identity=31.7365269461078, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788761, Length=202, Percent_Identity=27.7227722772277, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787164, Length=194, Percent_Identity=29.3814432989691, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1790739, Length=216, Percent_Identity=28.7037037037037, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786253, Length=219, Percent_Identity=32.4200913242009, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787029, Length=212, Percent_Identity=24.5283018867925, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787712, Length=192, Percent_Identity=26.5625, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790467, Length=168, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI48995001, Length=247, Percent_Identity=27.1255060728745, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786345, Length=233, Percent_Identity=26.6094420600858, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786319, Length=201, Percent_Identity=29.3532338308458, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1789873, Length=222, Percent_Identity=27.9279279279279, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=400, Percent_Identity=30.5, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17555318, Length=494, Percent_Identity=26.7206477732794, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17553372, Length=520, Percent_Identity=29.8076923076923, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI193202349, Length=187, Percent_Identity=29.9465240641711, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=532, Percent_Identity=25.9398496240602, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6321121, Length=418, Percent_Identity=28.4688995215311, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324314, Length=357, Percent_Identity=28.2913165266106, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323278, Length=358, Percent_Identity=27.9329608938547, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6325030, Length=371, Percent_Identity=26.9541778975741, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24666836, Length=500, Percent_Identity=28.4, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24641342, Length=514, Percent_Identity=28.5992217898833, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24642252, Length=499, Percent_Identity=28.0561122244489, Blast_Score=158, Evalue=9e-39,
Organism=Drosophila melanogaster, GI18859989, Length=499, Percent_Identity=28.0561122244489, Blast_Score=158, Evalue=9e-39,
Organism=Drosophila melanogaster, GI24582014, Length=186, Percent_Identity=32.7956989247312, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582012, Length=186, Percent_Identity=32.7956989247312, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24666092, Length=286, Percent_Identity=28.3216783216783, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 69925; Mature: 69925

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVPLLRLDRICLTFGKTPLFNQACLAVEQGARIALVGRNGCGKSTLLKIAAGIIEPNEG
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCC
EIFRHPRATLRYLSQNPDCSGFEDVHAFVEAGLDHVPDAQWINTLLANLGFSGTEKLANL
CEEECCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHCC
SGGERRRVSLLQAIAAKPDILLLDEPTNHLDLPTIEWLEGTLFSLRSALVVISHDRRFLE
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEEECCHHHHH
NVTRSTVWLDRGITKRLEKRFSEFENWRDKALEEEALEQHKLRRQIAREEQWLRYGVTAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RKRNVRRLGALKELRQLHQTYKGPSGSALLTVAKSHDSGQLVLEAKRISKSYGERVIVKD
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEHHHHHHHHCCEEEEEE
FSLRVQRGDRIGLVGPNGIGKTTLLSVLIGQEAADSGTVKHGYNISMAFLDQQRILNEEE
EEEEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECHHHHCCHHH
TLAHYLTGGRGDTLVINGQERHVVSYMKDFLFLPEQARTPLKEFSGGERARLMLARLLSR
HHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCHHHCCCHHHCCCCHHHHHHHHHHHCC
PANFLILDEPTNDLDMETLDLLQEFIADFAGTVLLVSHDRDFLDRTVTHMLAPQGDGHWI
CCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCCCCCEE
LYAGGYSDMIAQNKHAALLGCKEGAVSQGKALSNPRVLENKNSNASTNRASMEPEKIKPR
EEECCCHHHHHCCCCCEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHCCCC
KLSYKQVYALEKLPEQIAVLQDEIKKIEQELFDPALYCNDKERFERLSIKLQEKQKLCAG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHCC
KEEEWLELELLREDIEGVKS
CCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVVPLLRLDRICLTFGKTPLFNQACLAVEQGARIALVGRNGCGKSTLLKIAAGIIEPNEG
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCC
EIFRHPRATLRYLSQNPDCSGFEDVHAFVEAGLDHVPDAQWINTLLANLGFSGTEKLANL
CEEECCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHCC
SGGERRRVSLLQAIAAKPDILLLDEPTNHLDLPTIEWLEGTLFSLRSALVVISHDRRFLE
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEEECCHHHHH
NVTRSTVWLDRGITKRLEKRFSEFENWRDKALEEEALEQHKLRRQIAREEQWLRYGVTAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RKRNVRRLGALKELRQLHQTYKGPSGSALLTVAKSHDSGQLVLEAKRISKSYGERVIVKD
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEHHHHHHHHCCEEEEEE
FSLRVQRGDRIGLVGPNGIGKTTLLSVLIGQEAADSGTVKHGYNISMAFLDQQRILNEEE
EEEEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECHHHHCCHHH
TLAHYLTGGRGDTLVINGQERHVVSYMKDFLFLPEQARTPLKEFSGGERARLMLARLLSR
HHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCHHHCCCHHHCCCCHHHHHHHHHHHCC
PANFLILDEPTNDLDMETLDLLQEFIADFAGTVLLVSHDRDFLDRTVTHMLAPQGDGHWI
CCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCCCCCEE
LYAGGYSDMIAQNKHAALLGCKEGAVSQGKALSNPRVLENKNSNASTNRASMEPEKIKPR
EEECCCHHHHHCCCCCEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHCCCC
KLSYKQVYALEKLPEQIAVLQDEIKKIEQELFDPALYCNDKERFERLSIKLQEKQKLCAG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHCC
KEEEWLELELLREDIEGVKS
CCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9139905; 7751275 [H]