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The map label for this gene is ppiD [H]

Identifier: 49475360

GI number: 49475360

Start: 665573

End: 667462

Strand: Reverse

Name: ppiD [H]

Synonym: BH05670

Alternate gene names: 49475360

Gene position: 667462-665573 (Counterclockwise)

Preceding gene: 49475374

Following gene: 49475350

Centisome position: 34.56

GC content: 36.77

Gene sequence:

>1890_bases
ATGCTTGACATCATAAGAAACGCCACAAATTCTTGGATTGCTAGAATTTTTCTTGCTATTTTGCTTTTATGTTTTATCCT
TTTATGGGGGATACCACAGTTACACACAAAAAGTGAAAGAGATCTTATCTCTTCTGGAGAGTCCATAATAACTATCGATG
ATTATCGTCTTGCACTGGCTGATCAAAGTGCACGTTTAGCACTCGCCTCTCGTCTTGGACGCATGTTCACACCAAATGAA
ATGCAGCAATACCAAATCCCCGCTTTTGTTTTTAATCAGTTACAACAAGATGTGCTCTTTGATGAACAAACGCGTCAAAT
GAAAATCAATCTTTCAAAAGATGCCATAGCCCGTAAAATTGGTGCGGATAATATGTTCCAAATAAATGGTGTCTTCAAAC
ATGATTTGTTTCGTAACTACCTTCAACAATTACATATAAGCGAAAGTAATTTCCTTGATTATTACACAAAAAAAGAAAAA
CGTAATCAGCTCATTTCAGCGTCACTGTCAGGGATGAAAGCACCAGATCTTTTTTATAAAGCACTCGCCTTTTATCAAAG
AGAAACCCGTATTGCCGATTATCTCGTTCTTGATCTAAAAGAAAAGGAAATAATTTCTGAACCTCATCAAGAAACGTTGC
AAAAATGGTTTGAAACACATAGAAATAAATTTCGTGTTCCAGAATACCGTACAATTTCTTTCTTATCCATGGAACTCGCT
GATTTTATAAAACCCAAAGATATCTCAGAAGATGAGGTAAAAAACTATTATACACAAAACTCCTCGCGTTTTATAACTCC
TGAAAAACGCACGATTGAAGAATTGCGTTTCCCTACACGCGAGGCTGCAGATAATGCAGTAAAAAAAATAGCCGATGGAT
TAAGCTTCGATGACTTAGTTAAAGCTGAAAACAAGACTCTCAATGACATAAAAAAAGGGCCTTTCACAGAAAATGAACTT
CCTAGTTATTTATCCTCTGAGATTTTTGAACTTAAACAAGGACAAATCAGTGCTGTAATCAATGATTTACAAGGTCCTGT
TATCATTCGTGTTACAGATATTACACCTGCAGGCCCCATTCCCTTTGAGAAAGTAGAAGACAATATTCGTCAAACACTTG
CTCAAAATCGTGCTGCTGATGATATACGTAACAGTTATACGGAAATTGAAAATGCACGTTTTGAAGGTGCTTCTTTCAAA
GAGCTTGCTGACCAATATAAATTACCCTTGCGAACAATTACCCTTGATAAAACAGGAAAAACAATTGAAGGCACAATACT
TACAGATCTACCCCAAAAAGATCTTTTGCTTAACTCCATTTATCAATCAAACGAAGGAGCTGATCTTGATCCACTCTCTC
TTCCAAATGGTGGGTATCTCTGGTACAAGATCAATACTATCATCCCTGCGCGGGATAAAACATTTGAAGAGGCAAAACAA
GAGGTCATTGCCCAATGGAAAAAAGAAGAAATCCAACGCCTTCTTGATGAAAAAGCCAAGGACGCTCTCAAACAGCTCAC
TGAAGGAAAAAGTCTTGTTTCTCTCGCACATATACTTGGTGTTACAAAACAAACAACACAGCCCCTTCGGCGCCAAGATT
CATCTGAAATCCTTGGATTTGAAGGCGTTAAAGCATTATTTTCTGGTCCAAAAGGTCACTATGGCATAGTAAAAGGTCCG
ATTGCAAAAAACCGTATCCTTTATCAAATAAAGGAAGTTACTACTCCTAAAGATATCTCTCCTCATACCCTTTCATCTGA
TATTCGTAGTAACATAGATATGATGATAAGAGAAGATCTAAAGCTAGAGATGCTGCATGTTGCCAATAAAGAACATCCTT
TAAAAATTAATAGCGCTAACTATAATCAAATCTTCCAAGCTCTTCAATAA

Upstream 100 bases:

>100_bases
ATAAAATGAAAGCAAGTCTTTAAGCTTGCATCTTACGCATCTTTATTGCAAATTCCGTTATTACTTTGATGATAACTCAT
GCTAAAAATGGAATTGAACG

Downstream 100 bases:

>100_bases
TAGTGTTGCAAATGATCTTAAGTATTTATTTAATAAAATTGTGCTTAGCGTTTTATCTGCAATTTAAAAATCAGGCAAAA
TTCTTTTTGCCTGAGTGTGG

Product: peptidyl-prolyl cis-trans isomerase protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 629; Mature: 629

Protein sequence:

>629_residues
MLDIIRNATNSWIARIFLAILLLCFILLWGIPQLHTKSERDLISSGESIITIDDYRLALADQSARLALASRLGRMFTPNE
MQQYQIPAFVFNQLQQDVLFDEQTRQMKINLSKDAIARKIGADNMFQINGVFKHDLFRNYLQQLHISESNFLDYYTKKEK
RNQLISASLSGMKAPDLFYKALAFYQRETRIADYLVLDLKEKEIISEPHQETLQKWFETHRNKFRVPEYRTISFLSMELA
DFIKPKDISEDEVKNYYTQNSSRFITPEKRTIEELRFPTREAADNAVKKIADGLSFDDLVKAENKTLNDIKKGPFTENEL
PSYLSSEIFELKQGQISAVINDLQGPVIIRVTDITPAGPIPFEKVEDNIRQTLAQNRAADDIRNSYTEIENARFEGASFK
ELADQYKLPLRTITLDKTGKTIEGTILTDLPQKDLLLNSIYQSNEGADLDPLSLPNGGYLWYKINTIIPARDKTFEEAKQ
EVIAQWKKEEIQRLLDEKAKDALKQLTEGKSLVSLAHILGVTKQTTQPLRRQDSSEILGFEGVKALFSGPKGHYGIVKGP
IAKNRILYQIKEVTTPKDISPHTLSSDIRSNIDMMIREDLKLEMLHVANKEHPLKINSANYNQIFQALQ

Sequences:

>Translated_629_residues
MLDIIRNATNSWIARIFLAILLLCFILLWGIPQLHTKSERDLISSGESIITIDDYRLALADQSARLALASRLGRMFTPNE
MQQYQIPAFVFNQLQQDVLFDEQTRQMKINLSKDAIARKIGADNMFQINGVFKHDLFRNYLQQLHISESNFLDYYTKKEK
RNQLISASLSGMKAPDLFYKALAFYQRETRIADYLVLDLKEKEIISEPHQETLQKWFETHRNKFRVPEYRTISFLSMELA
DFIKPKDISEDEVKNYYTQNSSRFITPEKRTIEELRFPTREAADNAVKKIADGLSFDDLVKAENKTLNDIKKGPFTENEL
PSYLSSEIFELKQGQISAVINDLQGPVIIRVTDITPAGPIPFEKVEDNIRQTLAQNRAADDIRNSYTEIENARFEGASFK
ELADQYKLPLRTITLDKTGKTIEGTILTDLPQKDLLLNSIYQSNEGADLDPLSLPNGGYLWYKINTIIPARDKTFEEAKQ
EVIAQWKKEEIQRLLDEKAKDALKQLTEGKSLVSLAHILGVTKQTTQPLRRQDSSEILGFEGVKALFSGPKGHYGIVKGP
IAKNRILYQIKEVTTPKDISPHTLSSDIRSNIDMMIREDLKLEMLHVANKEHPLKINSANYNQIFQALQ
>Mature_629_residues
MLDIIRNATNSWIARIFLAILLLCFILLWGIPQLHTKSERDLISSGESIITIDDYRLALADQSARLALASRLGRMFTPNE
MQQYQIPAFVFNQLQQDVLFDEQTRQMKINLSKDAIARKIGADNMFQINGVFKHDLFRNYLQQLHISESNFLDYYTKKEK
RNQLISASLSGMKAPDLFYKALAFYQRETRIADYLVLDLKEKEIISEPHQETLQKWFETHRNKFRVPEYRTISFLSMELA
DFIKPKDISEDEVKNYYTQNSSRFITPEKRTIEELRFPTREAADNAVKKIADGLSFDDLVKAENKTLNDIKKGPFTENEL
PSYLSSEIFELKQGQISAVINDLQGPVIIRVTDITPAGPIPFEKVEDNIRQTLAQNRAADDIRNSYTEIENARFEGASFK
ELADQYKLPLRTITLDKTGKTIEGTILTDLPQKDLLLNSIYQSNEGADLDPLSLPNGGYLWYKINTIIPARDKTFEEAKQ
EVIAQWKKEEIQRLLDEKAKDALKQLTEGKSLVSLAHILGVTKQTTQPLRRQDSSEILGFEGVKALFSGPKGHYGIVKGP
IAKNRILYQIKEVTTPKDISPHTLSSDIRSNIDMMIREDLKLEMLHVANKEHPLKINSANYNQIFQALQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=401, Percent_Identity=24.9376558603491, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 72157; Mature: 72157

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDIIRNATNSWIARIFLAILLLCFILLWGIPQLHTKSERDLISSGESIITIDDYRLALA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCEEEEECEEEEEC
DQSARLALASRLGRMFTPNEMQQYQIPAFVFNQLQQDVLFDEQTRQMKINLSKDAIARKI
CCHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHH
GADNMFQINGVFKHDLFRNYLQQLHISESNFLDYYTKKEKRNQLISASLSGMKAPDLFYK
CCCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALAFYQRETRIADYLVLDLKEKEIISEPHQETLQKWFETHRNKFRVPEYRTISFLSMELA
HHHHHHHHHHHHHHHEEECCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
DFIKPKDISEDEVKNYYTQNSSRFITPEKRTIEELRFPTREAADNAVKKIADGLSFDDLV
HHCCCCCCCHHHHHHHHHCCCCEEECCCHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHH
KAENKTLNDIKKGPFTENELPSYLSSEIFELKQGQISAVINDLQGPVIIRVTDITPAGPI
HHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCCC
PFEKVEDNIRQTLAQNRAADDIRNSYTEIENARFEGASFKELADQYKLPLRTITLDKTGK
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCCC
TIEGTILTDLPQKDLLLNSIYQSNEGADLDPLSLPNGGYLWYKINTIIPARDKTFEEAKQ
EEECEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHH
EVIAQWKKEEIQRLLDEKAKDALKQLTEGKSLVSLAHILGVTKQTTQPLRRQDSSEILGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCH
EGVKALFSGPKGHYGIVKGPIAKNRILYQIKEVTTPKDISPHTLSSDIRSNIDMMIREDL
HHHHHHHCCCCCCCCCEECCCHHCHHHHHHHHCCCCCCCCCCHHHHHHHHCHHHHHHHCC
KLEMLHVANKEHPLKINSANYNQIFQALQ
HHHHHHHCCCCCCEEECCCCHHHHHHHHC
>Mature Secondary Structure
MLDIIRNATNSWIARIFLAILLLCFILLWGIPQLHTKSERDLISSGESIITIDDYRLALA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCEEEEECEEEEEC
DQSARLALASRLGRMFTPNEMQQYQIPAFVFNQLQQDVLFDEQTRQMKINLSKDAIARKI
CCHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHH
GADNMFQINGVFKHDLFRNYLQQLHISESNFLDYYTKKEKRNQLISASLSGMKAPDLFYK
CCCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALAFYQRETRIADYLVLDLKEKEIISEPHQETLQKWFETHRNKFRVPEYRTISFLSMELA
HHHHHHHHHHHHHHHEEECCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
DFIKPKDISEDEVKNYYTQNSSRFITPEKRTIEELRFPTREAADNAVKKIADGLSFDDLV
HHCCCCCCCHHHHHHHHHCCCCEEECCCHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHH
KAENKTLNDIKKGPFTENELPSYLSSEIFELKQGQISAVINDLQGPVIIRVTDITPAGPI
HHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCCC
PFEKVEDNIRQTLAQNRAADDIRNSYTEIENARFEGASFKELADQYKLPLRTITLDKTGK
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCCC
TIEGTILTDLPQKDLLLNSIYQSNEGADLDPLSLPNGGYLWYKINTIIPARDKTFEEAKQ
EEECEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHH
EVIAQWKKEEIQRLLDEKAKDALKQLTEGKSLVSLAHILGVTKQTTQPLRRQDSSEILGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCH
EGVKALFSGPKGHYGIVKGPIAKNRILYQIKEVTTPKDISPHTLSSDIRSNIDMMIREDL
HHHHHHHCCCCCCCCCEECCCHHCHHHHHHHHCCCCCCCCCCHHHHHHHHCHHHHHHHCC
KLEMLHVANKEHPLKINSANYNQIFQALQ
HHHHHHHCCCCCCEEECCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]