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The map label for this gene is tldD [H]

Identifier: 49475235

GI number: 49475235

Start: 504031

End: 505449

Strand: Reverse

Name: tldD [H]

Synonym: BH04380

Alternate gene names: 49475235

Gene position: 505449-504031 (Counterclockwise)

Preceding gene: 49475236

Following gene: 49475226

Centisome position: 26.17

GC content: 41.16

Gene sequence:

>1419_bases
ATGAAATCCCTGATTGATCATTTTGATATTGCTTCAGCTAAAGTACAATCACTTGTGCAAGAAACACTTCACCATGCTGA
TGATGGCGAGCTTTATCTTGAGTATACAGAAAGTGAAACGCTTTTATTTGACAATAGACAGCTTAAAAATGGCTCATTTC
ATCAAGATATGGGGTTTGGTCTGCGTGTTGTTGCTGGAGAAGCTACTGGATATGCACACTCTAGTGAATTATCAGCTGCC
GCACTCAAACGTGCTAGTGAAGCAGCTAAAACTGTTACCTATAAGAATCATGCAGGGCCTTATAGCGTAGCACCTCAACA
AACAAACAAAAAACTTTATCAGCCACATAATCCCCTTAATGCTCCATCATTTGAAGAAAAAAGTGCACTTTTGCAAAAAA
TTGATGACTATTTACGTGCAAAAAATGATAAATTGCATCAAGTAACTGTTTCTCTTTCCGGTTCACTACAGCATGTTGAA
ATTTTACGCGCTGATGGGAATCTTGTGCGTGATATCCGTCCTCTTGTACGACTTTCCATATCTGTGGTTGCTGCTGAGGG
TAATCGGCGTGAAAATGGCTTCTATGGATGTGGTGGACGACAAGCATTTAGTCAATTCATTAGCGAAGAAAATTGGAAAA
AAGCTGCCGATGAGGCTTTGCGTATGGCTCTCATAAACTTAGAAGCAGAAGCAGCTCCAGCAGGAACATTTGATGTTGTC
TTAGCCAATGGATGGCCTGGCGTTATGCTTCATGAAGCCGTAGGCCATGGATTGGAAGGAGACTTTAACCGCAAAAAAAC
ATCTGCTTTTTCTGGGCTTTTGGGTCAACAAGTTGCCGCAAAAGGTGTCACAGTTGTTGATGATGGTACAATTCCAAAAT
GTCGTGGTTCACTCACCATTGATGATGAAGGTACGCCATCAGGATATAACATTCTTATTGAAAATGGAAAACTTGTTGGT
TTTATGCAAGATAGGCTAAATGCTCGGCTTATGGGTGTTAATCCAACTGGAAATGGACGGCGTGAATCCTATGCATATGC
ACCAATGCCACGAATGACAAATACGATCATGCTAGGAGGCGACAAAACACCTGAAGAAATTCTATCTTCACTCAAAAGCG
GTATCTATGCTGTTTCCTTTGGTGGTGGACAGGTTGATATCACTTCTGGAAAATTCGTCTTTGAATGCACTGAAGCTTAC
AGAGTAGAAAATGGCAAAATTGTAGCCCCCATTAAAGGTGCAACTCTTATTGGAAACGGGCCAGAAGCCATGAAACGTAT
TACAATGATTGGAAATGATAGTAAACTTGATAATGGTATCGGTACGTGTGGAAAAGCCGGACAAAGCGTACCTGTTGGCG
TTGGACAACCTCATCTGCGCATTAATAATATGACAATTGGTGGAACAGAACTTACATGA

Upstream 100 bases:

>100_bases
TTTACCAATGTAATAAAATTTGTCTCTCAGAATCTGTCTTATAGTTTCTTGAAAAAACAAATGAAATCTTCCAGACATCA
ATGAAAATAGGATAACCGTC

Downstream 100 bases:

>100_bases
AAGATACAAATCAACTTGATTAAAAAAATTCTCAACAGAATTTAAAAGAGTTTTCAATCTAAGCTAAAGCTTCCAATTTG
CCTTTATTTTTCGTTTGCTC

Product: tldD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MKSLIDHFDIASAKVQSLVQETLHHADDGELYLEYTESETLLFDNRQLKNGSFHQDMGFGLRVVAGEATGYAHSSELSAA
ALKRASEAAKTVTYKNHAGPYSVAPQQTNKKLYQPHNPLNAPSFEEKSALLQKIDDYLRAKNDKLHQVTVSLSGSLQHVE
ILRADGNLVRDIRPLVRLSISVVAAEGNRRENGFYGCGGRQAFSQFISEENWKKAADEALRMALINLEAEAAPAGTFDVV
LANGWPGVMLHEAVGHGLEGDFNRKKTSAFSGLLGQQVAAKGVTVVDDGTIPKCRGSLTIDDEGTPSGYNILIENGKLVG
FMQDRLNARLMGVNPTGNGRRESYAYAPMPRMTNTIMLGGDKTPEEILSSLKSGIYAVSFGGGQVDITSGKFVFECTEAY
RVENGKIVAPIKGATLIGNGPEAMKRITMIGNDSKLDNGIGTCGKAGQSVPVGVGQPHLRINNMTIGGTELT

Sequences:

>Translated_472_residues
MKSLIDHFDIASAKVQSLVQETLHHADDGELYLEYTESETLLFDNRQLKNGSFHQDMGFGLRVVAGEATGYAHSSELSAA
ALKRASEAAKTVTYKNHAGPYSVAPQQTNKKLYQPHNPLNAPSFEEKSALLQKIDDYLRAKNDKLHQVTVSLSGSLQHVE
ILRADGNLVRDIRPLVRLSISVVAAEGNRRENGFYGCGGRQAFSQFISEENWKKAADEALRMALINLEAEAAPAGTFDVV
LANGWPGVMLHEAVGHGLEGDFNRKKTSAFSGLLGQQVAAKGVTVVDDGTIPKCRGSLTIDDEGTPSGYNILIENGKLVG
FMQDRLNARLMGVNPTGNGRRESYAYAPMPRMTNTIMLGGDKTPEEILSSLKSGIYAVSFGGGQVDITSGKFVFECTEAY
RVENGKIVAPIKGATLIGNGPEAMKRITMIGNDSKLDNGIGTCGKAGQSVPVGVGQPHLRINNMTIGGTELT
>Mature_472_residues
MKSLIDHFDIASAKVQSLVQETLHHADDGELYLEYTESETLLFDNRQLKNGSFHQDMGFGLRVVAGEATGYAHSSELSAA
ALKRASEAAKTVTYKNHAGPYSVAPQQTNKKLYQPHNPLNAPSFEEKSALLQKIDDYLRAKNDKLHQVTVSLSGSLQHVE
ILRADGNLVRDIRPLVRLSISVVAAEGNRRENGFYGCGGRQAFSQFISEENWKKAADEALRMALINLEAEAAPAGTFDVV
LANGWPGVMLHEAVGHGLEGDFNRKKTSAFSGLLGQQVAAKGVTVVDDGTIPKCRGSLTIDDEGTPSGYNILIENGKLVG
FMQDRLNARLMGVNPTGNGRRESYAYAPMPRMTNTIMLGGDKTPEEILSSLKSGIYAVSFGGGQVDITSGKFVFECTEAY
RVENGKIVAPIKGATLIGNGPEAMKRITMIGNDSKLDNGIGTCGKAGQSVPVGVGQPHLRINNMTIGGTELT

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=447, Percent_Identity=54.1387024608501, Blast_Score=485, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50797; Mature: 50797

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLIDHFDIASAKVQSLVQETLHHADDGELYLEYTESETLLFDNRQLKNGSFHQDMGFG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCC
LRVVAGEATGYAHSSELSAAALKRASEAAKTVTYKNHAGPYSVAPQQTNKKLYQPHNPLN
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHCCCCCCCCCCCC
APSFEEKSALLQKIDDYLRAKNDKLHQVTVSLSGSLQHVEILRADGNLVRDIRPLVRLSI
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEEECCCCHHHHHHHHHHEEE
SVVAAEGNRRENGFYGCGGRQAFSQFISEENWKKAADEALRMALINLEAEAAPAGTFDVV
EEEEECCCCCCCCEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCCCCCCCEEEE
LANGWPGVMLHEAVGHGLEGDFNRKKTSAFSGLLGQQVAAKGVTVVDDGTIPKCRGSLTI
EECCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEE
DDEGTPSGYNILIENGKLVGFMQDRLNARLMGVNPTGNGRRESYAYAPMPRMTNTIMLGG
CCCCCCCCCEEEEECCEEEEEEHHCCCEEEEEECCCCCCCCCCEEECCCCCCCCEEEECC
DKTPEEILSSLKSGIYAVSFGGGQVDITSGKFVFECTEAYRVENGKIVAPIKGATLIGNG
CCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEEEHHEEECCCEEEEEECCCEEECCC
PEAMKRITMIGNDSKLDNGIGTCGKAGQSVPVGVGQPHLRINNMTIGGTELT
HHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure
MKSLIDHFDIASAKVQSLVQETLHHADDGELYLEYTESETLLFDNRQLKNGSFHQDMGFG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCC
LRVVAGEATGYAHSSELSAAALKRASEAAKTVTYKNHAGPYSVAPQQTNKKLYQPHNPLN
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHCCCCCCCCCCCC
APSFEEKSALLQKIDDYLRAKNDKLHQVTVSLSGSLQHVEILRADGNLVRDIRPLVRLSI
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEEECCCCHHHHHHHHHHEEE
SVVAAEGNRRENGFYGCGGRQAFSQFISEENWKKAADEALRMALINLEAEAAPAGTFDVV
EEEEECCCCCCCCEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCCCCCCCEEEE
LANGWPGVMLHEAVGHGLEGDFNRKKTSAFSGLLGQQVAAKGVTVVDDGTIPKCRGSLTI
EECCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEE
DDEGTPSGYNILIENGKLVGFMQDRLNARLMGVNPTGNGRRESYAYAPMPRMTNTIMLGG
CCCCCCCCCEEEEECCEEEEEEHHCCCEEEEEECCCCCCCCCCEEECCCCCCCCEEEECC
DKTPEEILSSLKSGIYAVSFGGGQVDITSGKFVFECTEAYRVENGKIVAPIKGATLIGNG
CCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEEEHHEEECCCEEEEEECCCEEECCC
PEAMKRITMIGNDSKLDNGIGTCGKAGQSVPVGVGQPHLRINNMTIGGTELT
HHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]