Click here to switch to the map view.

The map label for this gene is arrD [H]

Identifier: 49475100

GI number: 49475100

Start: 374890

End: 375552

Strand: Reverse

Name: arrD [H]

Synonym: BH02950

Alternate gene names: 49475100

Gene position: 375552-374890 (Counterclockwise)

Preceding gene: 49475103

Following gene: 49475099

Centisome position: 19.45

GC content: 44.04

Gene sequence:

>663_bases
ATGAGAACAATATCACAAGAAGGACTAGCACTGATTAAACAATGGGAAGGTTTGCGTTTGAATGCCTATAAAGATGCCAT
TGGGGTATGGACAATCGGTTATGGACATACAAACAATGCCGGAAAACCTTTTGTTTACAAAGGCATGGCAATCACTGAAA
AACAAGCTGAAGAACTTCTTTGCCAAGATTTAAGACAATTTGAAAATACCGTTGAACAAGCGGTTCAAGTTTCCTTAACG
GATGAACAATTCGCGGCATTGGTCTCCTTTTGCTATAATGTAGGAACAACAGCTTTTTGCAATTCGACCTTGTTAAGGAA
ACTCAATAGTGGCGATTATGAAGCGATCCCAACCGAATTACAGAAATGGACCAAAGCCGGTGGTAAGCGCTTACAAGGTC
TTGTACACCGGCGTGCAGCTGAAGCAGGATTATGGGCGAAAGGTGCTTTTGTTTCCTCGAATTACCAAACCGTAGAAACG
CAAGCACCAACAGGGCTTTTCAAAGCCGAAGCCCTTGCACCAGTCATTGGTTCTTTTTCTGGGCTTGGTGGCTTATTAGC
CGGCAATGGTCCAGTGCAATGGGCGCTCGCCACTATCATGGTTTTAGCCGCCTGTGCTGGCATTTTCTTTGTTGCTAAAC
GTTTTCAGGAACACCGTTTATGA

Upstream 100 bases:

>100_bases
AAGCTACATAGGTTTTAACAAGCCAACCTTCCGAATGGGAAAGAGGTCAATTTTTAAATCCAGCTCTGCTTTTTGCAGGG
CTTTTTTTATGGAGAAGCAT

Downstream 100 bases:

>100_bases
TCTTATGGATGAAAAGAAATCTACTATTAACAGGCGCGGCTCTAGCCGCTTTTTTTATGGCTTTGGCAAAAGCTTTTACC
CTTGGAAAAAAAGCAGAACA

Product: Phage related lysozyme

Products: NA

Alternate protein names: Endolysin; Lysis protein; Muramidase [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MRTISQEGLALIKQWEGLRLNAYKDAIGVWTIGYGHTNNAGKPFVYKGMAITEKQAEELLCQDLRQFENTVEQAVQVSLT
DEQFAALVSFCYNVGTTAFCNSTLLRKLNSGDYEAIPTELQKWTKAGGKRLQGLVHRRAAEAGLWAKGAFVSSNYQTVET
QAPTGLFKAEALAPVIGSFSGLGGLLAGNGPVQWALATIMVLAACAGIFFVAKRFQEHRL

Sequences:

>Translated_220_residues
MRTISQEGLALIKQWEGLRLNAYKDAIGVWTIGYGHTNNAGKPFVYKGMAITEKQAEELLCQDLRQFENTVEQAVQVSLT
DEQFAALVSFCYNVGTTAFCNSTLLRKLNSGDYEAIPTELQKWTKAGGKRLQGLVHRRAAEAGLWAKGAFVSSNYQTVET
QAPTGLFKAEALAPVIGSFSGLGGLLAGNGPVQWALATIMVLAACAGIFFVAKRFQEHRL
>Mature_220_residues
MRTISQEGLALIKQWEGLRLNAYKDAIGVWTIGYGHTNNAGKPFVYKGMAITEKQAEELLCQDLRQFENTVEQAVQVSLT
DEQFAALVSFCYNVGTTAFCNSTLLRKLNSGDYEAIPTELQKWTKAGGKRLQGLVHRRAAEAGLWAKGAFVSSNYQTVET
QAPTGLFKAEALAPVIGSFSGLGGLLAGNGPVQWALATIMVLAACAGIFFVAKRFQEHRL

Specific function: Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity [H]

COG id: COG3772

COG function: function code R; Phage-related lysozyme (muraminidase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 24 family [H]

Homologues:

Organism=Escherichia coli, GI1786768, Length=126, Percent_Identity=40.4761904761905, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787836, Length=142, Percent_Identity=30.9859154929577, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002196 [H]

Pfam domain/function: PF00959 Phage_lysozyme [H]

EC number: =3.2.1.17 [H]

Molecular weight: Translated: 23951; Mature: 23951

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTISQEGLALIKQWEGLRLNAYKDAIGVWTIGYGHTNNAGKPFVYKGMAITEKQAEELL
CCCCCHHHHHHHHHCCCCEEEHHHCCCEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHH
CQDLRQFENTVEQAVQVSLTDEQFAALVSFCYNVGTTAFCNSTLLRKLNSGDYEAIPTEL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHH
QKWTKAGGKRLQGLVHRRAAEAGLWAKGAFVSSNYQTVETQAPTGLFKAEALAPVIGSFS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEECCCCCCHHHHHHHHHHHHHHH
GLGGLLAGNGPVQWALATIMVLAACAGIFFVAKRFQEHRL
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRTISQEGLALIKQWEGLRLNAYKDAIGVWTIGYGHTNNAGKPFVYKGMAITEKQAEELL
CCCCCHHHHHHHHHCCCCEEEHHHCCCEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHH
CQDLRQFENTVEQAVQVSLTDEQFAALVSFCYNVGTTAFCNSTLLRKLNSGDYEAIPTEL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHH
QKWTKAGGKRLQGLVHRRAAEAGLWAKGAFVSSNYQTVETQAPTGLFKAEALAPVIGSFS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEECCCCCCHHHHHHHHHHHHHHH
GLGGLLAGNGPVQWALATIMVLAACAGIFFVAKRFQEHRL
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]