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The map label for this gene is lnt [H]

Identifier: 49475034

GI number: 49475034

Start: 297921

End: 299555

Strand: Reverse

Name: lnt [H]

Synonym: BH02220

Alternate gene names: 49475034

Gene position: 299555-297921 (Counterclockwise)

Preceding gene: 49475035

Following gene: 49475033

Centisome position: 15.51

GC content: 38.53

Gene sequence:

>1635_bases
ATGAAAGTTTTAAACAAAATGTCATCTCCGAAGAGTAACTTCGTGTTTTTAAACAGTGTCAAGATGTCCTTGTTTTCCCT
CACTGGTTGGAAACGGCAAGGGGTGTTGTTTTTATGTGGTGCATTGACATCCTTTGCACTTCCGCCCTTTTATTTAACAC
CTCTCTGTTTTTTAACTTTTCCTGTCTTCATTGTTTTACTTGATAAAATCAGTGCTCTTCAAAACAATAGAAAATGCCTT
CTGATCTACGCTTTAAGCTGTGGAACCTTTGGCTTTGGTTATTTTATTTTTGGTTTTTGGTGGCTGTGTAATGCTTTACT
GACAGACCCAATTACTTTTGGATGGGCTGTGCCATTCGCTATTTTCTGCCCTCCCCTTTACCTTTCTCTTTATTGGTTTT
TTGCCGGTTTTATTGTCGGTTTTTTATGGACAAAAGGAATAGCACGCTTTTTTATTCTGGCTTTTGCGCTTGGACTAGCA
GAATGGTTACGTTCTATTTTATTCACAGGCTTTCCGTGGAATGCTCTTGGTTATACAGCTATGCCAACCCCTATGCTTAT
GCAATCCGATGCAATCTTCGGACTGTATGGAATGAATATCCTTGCCGTCTTCATCTACAGTTTACCCACTGTTTTATTCA
CAGATGAAAAAAAGAAAACCGCACTTTTTCTTTGCTTAGCGCTGATACTAGCCCACTGTGGTTTTGGATTTTATCGCCTC
AATACTGCCCCTAAAATGACTGATTATCAAAAAAGCAGTTATTGGGTGCGCATTGTTCAACCTTCTATAGAGCAAAACAC
AAAATTGAGCAATACTGAGCGAGAGGCTATATTTGCAGCTCATATGAATCTAAGTGCAACATCAATAGTGGAACAGCATC
CAGAACCCGACTTTATCGTATGGCCTGAAGCATCTATTCCTTATCTTCTCTATGATAACTCTACTATCACAATGCGCATT
GCCTCTCTTCTCAAGCCAAAACAATGGGCTATTATTGGTGCTATACGTGCCAGTAATAATCCTCTCAATGAAAAAACGCA
GTATTTTAATACAATTGCAGTCATTAATGCTACAGGAAATATTTTAACTACCTCTGATAAACTTCATTTGGTTCCTTTTG
GTGAATATCTGCCTTATCAGAATTTATTGAAAAAAATTGGATTGCATGCCCTTGCTGATACTATTGGTGGATATAGTACT
GCGAGTGTACGCAAAACTGTTATGATGCCGAATGGATTTTCTTATCTTCCTCTAATCTGTTATGAAGCAATATTTCCTAA
TGAAATGGTTTTTAAAGGTTCTCCTCCTCAAGCAATCATTAATGTTACAAATGATGCATGGTTTGGCGTAACACCCGGTC
CATACCAACATCTTCAACAAGTGCAGCTTCGTGCAGTTGAACTGGGAATCCCTCTTATAAGAGCAGCCAATAATGGAATA
TCAGCTGTCATTGATTCTTATGGACGAATCGTTGTAGCTCTCCAGCAAAATGCTGTTGGCATTGTTGATTCACCAATTCC
ATCACCCATTACCCCCATAGGAAACAATGAATACAGGATATTCTCTACTTTCATCTTATTCATTCTTATGCTATTGTGCG
GACTCGGTTTTGGTTCTACAAAACAGCTTAAATGA

Upstream 100 bases:

>100_bases
AAAGGTGAAATCATTGAAGCGGTGCCAGGTTATCGATTCCGTATTTTAGAAGCTGATAAACGTCGGATTAAGCGCTTACG
TATTTTTCGTATTCCGGAGA

Downstream 100 bases:

>100_bases
TCGGATGCCCACATTCCGGTACCGTATCATGTGTACCATTAAAGTTGGGAAAAACTATTACATATTGTTTTATTGTATGA
TAAATCAACCTCACATAAAT

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MKVLNKMSSPKSNFVFLNSVKMSLFSLTGWKRQGVLFLCGALTSFALPPFYLTPLCFLTFPVFIVLLDKISALQNNRKCL
LIYALSCGTFGFGYFIFGFWWLCNALLTDPITFGWAVPFAIFCPPLYLSLYWFFAGFIVGFLWTKGIARFFILAFALGLA
EWLRSILFTGFPWNALGYTAMPTPMLMQSDAIFGLYGMNILAVFIYSLPTVLFTDEKKKTALFLCLALILAHCGFGFYRL
NTAPKMTDYQKSSYWVRIVQPSIEQNTKLSNTEREAIFAAHMNLSATSIVEQHPEPDFIVWPEASIPYLLYDNSTITMRI
ASLLKPKQWAIIGAIRASNNPLNEKTQYFNTIAVINATGNILTTSDKLHLVPFGEYLPYQNLLKKIGLHALADTIGGYST
ASVRKTVMMPNGFSYLPLICYEAIFPNEMVFKGSPPQAIINVTNDAWFGVTPGPYQHLQQVQLRAVELGIPLIRAANNGI
SAVIDSYGRIVVALQQNAVGIVDSPIPSPITPIGNNEYRIFSTFILFILMLLCGLGFGSTKQLK

Sequences:

>Translated_544_residues
MKVLNKMSSPKSNFVFLNSVKMSLFSLTGWKRQGVLFLCGALTSFALPPFYLTPLCFLTFPVFIVLLDKISALQNNRKCL
LIYALSCGTFGFGYFIFGFWWLCNALLTDPITFGWAVPFAIFCPPLYLSLYWFFAGFIVGFLWTKGIARFFILAFALGLA
EWLRSILFTGFPWNALGYTAMPTPMLMQSDAIFGLYGMNILAVFIYSLPTVLFTDEKKKTALFLCLALILAHCGFGFYRL
NTAPKMTDYQKSSYWVRIVQPSIEQNTKLSNTEREAIFAAHMNLSATSIVEQHPEPDFIVWPEASIPYLLYDNSTITMRI
ASLLKPKQWAIIGAIRASNNPLNEKTQYFNTIAVINATGNILTTSDKLHLVPFGEYLPYQNLLKKIGLHALADTIGGYST
ASVRKTVMMPNGFSYLPLICYEAIFPNEMVFKGSPPQAIINVTNDAWFGVTPGPYQHLQQVQLRAVELGIPLIRAANNGI
SAVIDSYGRIVVALQQNAVGIVDSPIPSPITPIGNNEYRIFSTFILFILMLLCGLGFGSTKQLK
>Mature_544_residues
MKVLNKMSSPKSNFVFLNSVKMSLFSLTGWKRQGVLFLCGALTSFALPPFYLTPLCFLTFPVFIVLLDKISALQNNRKCL
LIYALSCGTFGFGYFIFGFWWLCNALLTDPITFGWAVPFAIFCPPLYLSLYWFFAGFIVGFLWTKGIARFFILAFALGLA
EWLRSILFTGFPWNALGYTAMPTPMLMQSDAIFGLYGMNILAVFIYSLPTVLFTDEKKKTALFLCLALILAHCGFGFYRL
NTAPKMTDYQKSSYWVRIVQPSIEQNTKLSNTEREAIFAAHMNLSATSIVEQHPEPDFIVWPEASIPYLLYDNSTITMRI
ASLLKPKQWAIIGAIRASNNPLNEKTQYFNTIAVINATGNILTTSDKLHLVPFGEYLPYQNLLKKIGLHALADTIGGYST
ASVRKTVMMPNGFSYLPLICYEAIFPNEMVFKGSPPQAIINVTNDAWFGVTPGPYQHLQQVQLRAVELGIPLIRAANNGI
SAVIDSYGRIVVALQQNAVGIVDSPIPSPITPIGNNEYRIFSTFILFILMLLCGLGFGSTKQLK

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=490, Percent_Identity=29.1836734693878, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 60773; Mature: 60773

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLNKMSSPKSNFVFLNSVKMSLFSLTGWKRQGVLFLCGALTSFALPPFYLTPLCFLTF
CCCHHHCCCCCCCEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
PVFIVLLDKISALQNNRKCLLIYALSCGTFGFGYFIFGFWWLCNALLTDPITFGWAVPFA
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IFCPPLYLSLYWFFAGFIVGFLWTKGIARFFILAFALGLAEWLRSILFTGFPWNALGYTA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
MPTPMLMQSDAIFGLYGMNILAVFIYSLPTVLFTDEKKKTALFLCLALILAHCGFGFYRL
CCCCHHCCCCCEEHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEE
NTAPKMTDYQKSSYWVRIVQPSIEQNTKLSNTEREAIFAAHMNLSATSIVEQHPEPDFIV
CCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHEEEEEECCCCHHHHHHHCCCCCEEE
WPEASIPYLLYDNSTITMRIASLLKPKQWAIIGAIRASNNPLNEKTQYFNTIAVINATGN
ECCCCCCEEEECCCEEEHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHEEEEEEECCCC
ILTTSDKLHLVPFGEYLPYQNLLKKIGLHALADTIGGYSTASVRKTVMMPNGFSYLPLIC
EEEECCCEEEEECHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCCCHHHHHH
YEAIFPNEMVFKGSPPQAIINVTNDAWFGVTPGPYQHLQQVQLRAVELGIPLIRAANNGI
HHHHCCCCEEECCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHHCCCCEEECCCCH
SAVIDSYGRIVVALQQNAVGIVDSPIPSPITPIGNNEYRIFSTFILFILMLLCGLGFGST
HHHHHCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
KQLK
CCCC
>Mature Secondary Structure
MKVLNKMSSPKSNFVFLNSVKMSLFSLTGWKRQGVLFLCGALTSFALPPFYLTPLCFLTF
CCCHHHCCCCCCCEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
PVFIVLLDKISALQNNRKCLLIYALSCGTFGFGYFIFGFWWLCNALLTDPITFGWAVPFA
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IFCPPLYLSLYWFFAGFIVGFLWTKGIARFFILAFALGLAEWLRSILFTGFPWNALGYTA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
MPTPMLMQSDAIFGLYGMNILAVFIYSLPTVLFTDEKKKTALFLCLALILAHCGFGFYRL
CCCCHHCCCCCEEHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEE
NTAPKMTDYQKSSYWVRIVQPSIEQNTKLSNTEREAIFAAHMNLSATSIVEQHPEPDFIV
CCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHEEEEEECCCCHHHHHHHCCCCCEEE
WPEASIPYLLYDNSTITMRIASLLKPKQWAIIGAIRASNNPLNEKTQYFNTIAVINATGN
ECCCCCCEEEECCCEEEHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHEEEEEEECCCC
ILTTSDKLHLVPFGEYLPYQNLLKKIGLHALADTIGGYSTASVRKTVMMPNGFSYLPLIC
EEEECCCEEEEECHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCCCHHHHHH
YEAIFPNEMVFKGSPPQAIINVTNDAWFGVTPGPYQHLQQVQLRAVELGIPLIRAANNGI
HHHHCCCCEEECCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHHCCCCEEECCCCH
SAVIDSYGRIVVALQQNAVGIVDSPIPSPITPIGNNEYRIFSTFILFILMLLCGLGFGST
HHHHHCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
KQLK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]