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The map label for this gene is argD [H]

Identifier: 49474927

GI number: 49474927

Start: 148532

End: 149737

Strand: Reverse

Name: argD [H]

Synonym: BH01090

Alternate gene names: 49474927

Gene position: 149737-148532 (Counterclockwise)

Preceding gene: 49474929

Following gene: 49474926

Centisome position: 7.75

GC content: 39.97

Gene sequence:

>1206_bases
ATGAATAGCACCACTATACAGCCACTTTATGAGTGCTTTGCTCGACGTAATTTGCATTTTGAACAAGGGAATGCTGTATG
GCTTATTTCCGATAAAGGAGAGCGTTATCTTGATTTCACGTCTGGCATTGCTGTCAATGTATTAGGATATGCACATCCAA
AATTGATTGATACTCTCAAAAGACAAGCTGAAAAACTTTGGCATGTTTCCAATCTTTTTCAATCACCTGAACAAGAAGCT
CTCGCCGCGCAGCTTTGCGTAAATAGTTTTGCTGATAAGGTTTTTTTCTGTAATTCCGGTGCTGAAGCAGTGGAATGCGC
ATTTAAAACTGCTCGTCACTACCATTATGCCTCTGGCCATCCAACACGCTTTGAAATTATTACTTTTGAAGATGCATTTC
ATGGGCGCACACTTGCAACGCTTGCTGCTACAGGACAAGAAAAATATTTGCAAGGTTTTGGACCAAAAGCTGACGGATTT
ATTCAAATTCCTTTATGTGATGAAATCGCTTTGCGTAATGCTATCAATAAAAATACTGCTGCCATCCTTATTGAACCCAT
TCAGGGAGAAGGAGGAATACGAACGGTATCTCATGAATATTTAAGGCTTTTGCGCAAAATATGCGATGAGAATGGTCTGT
TATTAATTTTGGATGAAATCCAAACAGGTATTGGACGAACAGGAAAGCTTTTTGCTTATGAATGGAGTGGTATTACACCT
GATATTCTTACTCTCGCAAAAGGACTGGGTGGCGGTTTTCCTTTAGGAGCTTGTCTTGCAACAGAAAAAGCTGCAAAAAG
TATGACACCAGGAACCCACGGATCAACATTTGGAGGCAATCTTCTTGGGATGGCTGTAGGCAAAACTGTTCTTGATATTA
TATTAGAACCTGGTCTTCTCGACCATGTTCAGCAAATGGGATATAAGCTAAAAAGCGGACTTTCAAATATTCTAAATGAC
TATCCTGACATTATCTGTGCAATTAACGGGGTAGGACTTATGTTGGGCATTCAGTGCGTGGTTCCCTCTCAGGTTGTCGT
TAGTGCATTGGAAAGTGAATATCTTTTGAGTGTTAGTGCCAACAACAACGTTGTGCGCTTCTTGCCTCCCCTTATTATCA
AGGAAGAAGAGGTAAACGAAAGTCTACATCGTATTGAAAAAGCAATTGCTTCTCTTTCCCAAACAAACAAAAAACAACTC
GTATAA

Upstream 100 bases:

>100_bases
AAATCACTAATGATACTGTATCCAAAGGTGCAACGTATTTTGTTTGCAGCGTTGTTTTGTTTGTTGTATCGCAGAGCTCG
AGAAATAAAGGAAATTAACG

Downstream 100 bases:

>100_bases
TCTCATAACACATAAGCTTCTCGCTATTGCATAGATTTATCTTCTTCATCTCCTTTAAACTAGGGAGCATATTCTTATCA
ACTATGGAAAATGCTCAAAA

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MNSTTIQPLYECFARRNLHFEQGNAVWLISDKGERYLDFTSGIAVNVLGYAHPKLIDTLKRQAEKLWHVSNLFQSPEQEA
LAAQLCVNSFADKVFFCNSGAEAVECAFKTARHYHYASGHPTRFEIITFEDAFHGRTLATLAATGQEKYLQGFGPKADGF
IQIPLCDEIALRNAINKNTAAILIEPIQGEGGIRTVSHEYLRLLRKICDENGLLLILDEIQTGIGRTGKLFAYEWSGITP
DILTLAKGLGGGFPLGACLATEKAAKSMTPGTHGSTFGGNLLGMAVGKTVLDIILEPGLLDHVQQMGYKLKSGLSNILND
YPDIICAINGVGLMLGIQCVVPSQVVVSALESEYLLSVSANNNVVRFLPPLIIKEEEVNESLHRIEKAIASLSQTNKKQL
V

Sequences:

>Translated_401_residues
MNSTTIQPLYECFARRNLHFEQGNAVWLISDKGERYLDFTSGIAVNVLGYAHPKLIDTLKRQAEKLWHVSNLFQSPEQEA
LAAQLCVNSFADKVFFCNSGAEAVECAFKTARHYHYASGHPTRFEIITFEDAFHGRTLATLAATGQEKYLQGFGPKADGF
IQIPLCDEIALRNAINKNTAAILIEPIQGEGGIRTVSHEYLRLLRKICDENGLLLILDEIQTGIGRTGKLFAYEWSGITP
DILTLAKGLGGGFPLGACLATEKAAKSMTPGTHGSTFGGNLLGMAVGKTVLDIILEPGLLDHVQQMGYKLKSGLSNILND
YPDIICAINGVGLMLGIQCVVPSQVVVSALESEYLLSVSANNNVVRFLPPLIIKEEEVNESLHRIEKAIASLSQTNKKQL
V
>Mature_401_residues
MNSTTIQPLYECFARRNLHFEQGNAVWLISDKGERYLDFTSGIAVNVLGYAHPKLIDTLKRQAEKLWHVSNLFQSPEQEA
LAAQLCVNSFADKVFFCNSGAEAVECAFKTARHYHYASGHPTRFEIITFEDAFHGRTLATLAATGQEKYLQGFGPKADGF
IQIPLCDEIALRNAINKNTAAILIEPIQGEGGIRTVSHEYLRLLRKICDENGLLLILDEIQTGIGRTGKLFAYEWSGITP
DILTLAKGLGGGFPLGACLATEKAAKSMTPGTHGSTFGGNLLGMAVGKTVLDIILEPGLLDHVQQMGYKLKSGLSNILND
YPDIICAINGVGLMLGIQCVVPSQVVVSALESEYLLSVSANNNVVRFLPPLIIKEEEVNESLHRIEKAIASLSQTNKKQL
V

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=384, Percent_Identity=34.375, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI284507298, Length=303, Percent_Identity=35.6435643564356, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI13994255, Length=379, Percent_Identity=29.8153034300792, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI37574042, Length=429, Percent_Identity=25.6410256410256, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI24119277, Length=416, Percent_Identity=25.4807692307692, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI226442705, Length=428, Percent_Identity=25.2336448598131, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI226442709, Length=394, Percent_Identity=25.8883248730964, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI188536080, Length=419, Percent_Identity=25.2983293556086, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI38679950, Length=419, Percent_Identity=25.2983293556086, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI38679946, Length=419, Percent_Identity=25.2983293556086, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI1789759, Length=377, Percent_Identity=41.9098143236074, Blast_Score=312, Evalue=3e-86,
Organism=Escherichia coli, GI1788044, Length=374, Percent_Identity=43.048128342246, Blast_Score=291, Evalue=5e-80,
Organism=Escherichia coli, GI145693181, Length=390, Percent_Identity=33.8461538461538, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1789016, Length=401, Percent_Identity=35.1620947630923, Blast_Score=197, Evalue=7e-52,
Organism=Escherichia coli, GI1787560, Length=391, Percent_Identity=32.9923273657289, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1786991, Length=395, Percent_Identity=30.379746835443, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786349, Length=337, Percent_Identity=29.9703264094956, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25144271, Length=384, Percent_Identity=33.59375, Blast_Score=201, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI32564660, Length=433, Percent_Identity=30.0230946882217, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI25144274, Length=275, Percent_Identity=34.1818181818182, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=421, Percent_Identity=28.0285035629454, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=451, Percent_Identity=22.8381374722838, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=390, Percent_Identity=39.2307692307692, Blast_Score=253, Evalue=5e-68,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=32.7543424317618, Blast_Score=183, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6324386, Length=322, Percent_Identity=27.639751552795, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6321456, Length=397, Percent_Identity=25.4408060453401, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357415, Length=381, Percent_Identity=34.9081364829396, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI161085790, Length=431, Percent_Identity=28.7703016241299, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI28574759, Length=415, Percent_Identity=28.9156626506024, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI21356575, Length=427, Percent_Identity=24.5901639344262, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281366494, Length=301, Percent_Identity=31.2292358803987, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24667139, Length=301, Percent_Identity=31.2292358803987, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24667143, Length=301, Percent_Identity=31.2292358803987, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43775; Mature: 43775

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSTTIQPLYECFARRNLHFEQGNAVWLISDKGERYLDFTSGIAVNVLGYAHPKLIDTLK
CCCCCHHHHHHHHHHCCCEEECCCEEEEEECCCCEEEEECCCCEEEEECCCCHHHHHHHH
RQAEKLWHVSNLFQSPEQEALAAQLCVNSFADKVFFCNSGAEAVECAFKTARHYHYASGH
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCCCCC
PTRFEIITFEDAFHGRTLATLAATGQEKYLQGFGPKADGFIQIPLCDEIALRNAINKNTA
CCEEEEEEECCCCCCCCHHHHHHCCHHHHHHCCCCCCCCEEEECCHHHHHHHHHCCCCCE
AILIEPIQGEGGIRTVSHEYLRLLRKICDENGLLLILDEIQTGIGRTGKLFAYEWSGITP
EEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEEEECCCCCH
DILTLAKGLGGGFPLGACLATEKAAKSMTPGTHGSTFGGNLLGMAVGKTVLDIILEPGLL
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
DHVQQMGYKLKSGLSNILNDYPDIICAINGVGLMLGIQCVVPSQVVVSALESEYLLSVSA
HHHHHHHHHHHHHHHHHHHHCCHHEEHHCCCEEEHHEEEECCHHHHHHHHCCCEEEEEEC
NNNVVRFLPPLIIKEEEVNESLHRIEKAIASLSQTNKKQLV
CCCEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure
MNSTTIQPLYECFARRNLHFEQGNAVWLISDKGERYLDFTSGIAVNVLGYAHPKLIDTLK
CCCCCHHHHHHHHHHCCCEEECCCEEEEEECCCCEEEEECCCCEEEEECCCCHHHHHHHH
RQAEKLWHVSNLFQSPEQEALAAQLCVNSFADKVFFCNSGAEAVECAFKTARHYHYASGH
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCCCCC
PTRFEIITFEDAFHGRTLATLAATGQEKYLQGFGPKADGFIQIPLCDEIALRNAINKNTA
CCEEEEEEECCCCCCCCHHHHHHCCHHHHHHCCCCCCCCEEEECCHHHHHHHHHCCCCCE
AILIEPIQGEGGIRTVSHEYLRLLRKICDENGLLLILDEIQTGIGRTGKLFAYEWSGITP
EEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEEEECCCCCH
DILTLAKGLGGGFPLGACLATEKAAKSMTPGTHGSTFGGNLLGMAVGKTVLDIILEPGLL
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
DHVQQMGYKLKSGLSNILNDYPDIICAINGVGLMLGIQCVVPSQVVVSALESEYLLSVSA
HHHHHHHHHHHHHHHHHHHHCCHHEEHHCCCEEEHHEEEECCHHHHHHHHCCCEEEEEEC
NNNVVRFLPPLIIKEEEVNESLHRIEKAIASLSQTNKKQLV
CCCEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]