Click here to switch to the map view.

The map label for this gene is mraW [H]

Identifier: 49186768

GI number: 49186768

Start: 3739898

End: 3740830

Strand: Reverse

Name: mraW [H]

Synonym: BAS3769

Alternate gene names: 49186768

Gene position: 3740830-3739898 (Counterclockwise)

Preceding gene: 49186769

Following gene: 49186767

Centisome position: 71.54

GC content: 38.26

Gene sequence:

>933_bases
ATGTTTAATCACGTAACAGTGCTTTTGAAGGAAACAGTAGATGGCTTAGATATAAAGCCAGATGGTACATATGTAGATTG
TACACTGGGGGGAGGAGGACATAGTTCTTATTTATTATCCCAATTAACTGAAGGCGGAAGATTAATCGCGTTTGATCAAG
ATGAGATAGCAATTCAAAATGCGAAAGAAAAATTCTCTTCATACGGTGAGCAGTTCATAACAGTAAAAAGTAATTTCCGT
TACCTATCTGAAAAACTACAGGAATTAGGTATAACAGAAGTAGACGGTATTTTATTTGATTTAGGTGTTTCATCCCCGCA
ATTAGATACACCAGAGCGCGGCTTTAGTTACCATCATGATGCACCGTTAGATATGCGAATGGATCAAGATGCCCCATTAA
CAGCCTATGATGCTGTAAATAGCTGGTCATATGAACAACTTGTAAGAATTTTCTTCCAGTATGGCGAAGAGAAATTTTCA
AAACAAATAGCAAGAAAAATTGAAGCGTATCGTGAAAATAAAGCTATTGAAACGACAGGGGAATTAGTAGAACTAATTAA
AGAGGGTATTCCAGCTCCTGCTCGTAGAACGGGTGGACATCCTGCGAAGCGAGTGTTCCAGGCAATCCGTATTGCGGTAA
ATGATGAATTGAAAGTGTTTGAAGAAGCGTTGGAATCTGCAATTGAGATGGTCAAGCCAGGCGGAAGAGTTAGTGTTATA
ACATTCCATTCTTTAGAAGACCGTATTTGCAAAACGACGTTTAAACGAAATAGTACAACGCCGCAATTGCCGCCAGGATT
ACCAATTATTCCTGATGAATTTAAGCCGAAGTTAAAGCTTATTACAAGAAAACCGATTTTACCTTCTGATATAGAGTTAG
AAGAAAATAATCGAGCGCGTTCTGCGAAATTGAGAATCGCTGAAAAACGATAA

Upstream 100 bases:

>100_bases
AGTCGTTCTTTCATAGTATTTCGTTCTCTAGTCGTGAAATATGCGTTTAGAGGAGGAGATACATTCAACATAATTAATTG
AAAAAAGAGTAGGTGCAACA

Downstream 100 bases:

>100_bases
AAAGGGGAGAGAGGTATGAGTAACTTAGCTGTAAAGTACAAACAACAAGCGCAAGAAGAGGTTCAGATTCAAACGCCCCC
ACAGCAAATGGTTCAGCCAA

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MFNHVTVLLKETVDGLDIKPDGTYVDCTLGGGGHSSYLLSQLTEGGRLIAFDQDEIAIQNAKEKFSSYGEQFITVKSNFR
YLSEKLQELGITEVDGILFDLGVSSPQLDTPERGFSYHHDAPLDMRMDQDAPLTAYDAVNSWSYEQLVRIFFQYGEEKFS
KQIARKIEAYRENKAIETTGELVELIKEGIPAPARRTGGHPAKRVFQAIRIAVNDELKVFEEALESAIEMVKPGGRVSVI
TFHSLEDRICKTTFKRNSTTPQLPPGLPIIPDEFKPKLKLITRKPILPSDIELEENNRARSAKLRIAEKR

Sequences:

>Translated_310_residues
MFNHVTVLLKETVDGLDIKPDGTYVDCTLGGGGHSSYLLSQLTEGGRLIAFDQDEIAIQNAKEKFSSYGEQFITVKSNFR
YLSEKLQELGITEVDGILFDLGVSSPQLDTPERGFSYHHDAPLDMRMDQDAPLTAYDAVNSWSYEQLVRIFFQYGEEKFS
KQIARKIEAYRENKAIETTGELVELIKEGIPAPARRTGGHPAKRVFQAIRIAVNDELKVFEEALESAIEMVKPGGRVSVI
TFHSLEDRICKTTFKRNSTTPQLPPGLPIIPDEFKPKLKLITRKPILPSDIELEENNRARSAKLRIAEKR
>Mature_310_residues
MFNHVTVLLKETVDGLDIKPDGTYVDCTLGGGGHSSYLLSQLTEGGRLIAFDQDEIAIQNAKEKFSSYGEQFITVKSNFR
YLSEKLQELGITEVDGILFDLGVSSPQLDTPERGFSYHHDAPLDMRMDQDAPLTAYDAVNSWSYEQLVRIFFQYGEEKFS
KQIARKIEAYRENKAIETTGELVELIKEGIPAPARRTGGHPAKRVFQAIRIAVNDELKVFEEALESAIEMVKPGGRVSVI
TFHSLEDRICKTTFKRNSTTPQLPPGLPIIPDEFKPKLKLITRKPILPSDIELEENNRARSAKLRIAEKR

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=339, Percent_Identity=35.1032448377581, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI165377202, Length=191, Percent_Identity=37.696335078534, Blast_Score=108, Evalue=6e-24,
Organism=Escherichia coli, GI1786270, Length=312, Percent_Identity=45.5128205128205, Blast_Score=253, Evalue=8e-69,
Organism=Drosophila melanogaster, GI62472493, Length=330, Percent_Identity=37.2727272727273, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI28571637, Length=330, Percent_Identity=37.2727272727273, Blast_Score=170, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 34931; Mature: 34931

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNHVTVLLKETVDGLDIKPDGTYVDCTLGGGGHSSYLLSQLTEGGRLIAFDQDEIAIQN
CCCHHEEHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEECCCHHHHHH
AKEKFSSYGEQFITVKSNFRYLSEKLQELGITEVDGILFDLGVSSPQLDTPERGFSYHHD
HHHHHHHHCCEEEEEHHHHHHHHHHHHHCCCCHHHHEEEECCCCCCCCCCCCCCCCCCCC
APLDMRMDQDAPLTAYDAVNSWSYEQLVRIFFQYGEEKFSKQIARKIEAYRENKAIETTG
CCCCCCCCCCCCEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ELVELIKEGIPAPARRTGGHPAKRVFQAIRIAVNDELKVFEEALESAIEMVKPGGRVSVI
HHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEE
TFHSLEDRICKTTFKRNSTTPQLPPGLPIIPDEFKPKLKLITRKPILPSDIELEENNRAR
EECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCEECCCCCCC
SAKLRIAEKR
HHEEEEECCC
>Mature Secondary Structure
MFNHVTVLLKETVDGLDIKPDGTYVDCTLGGGGHSSYLLSQLTEGGRLIAFDQDEIAIQN
CCCHHEEHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEECCCHHHHHH
AKEKFSSYGEQFITVKSNFRYLSEKLQELGITEVDGILFDLGVSSPQLDTPERGFSYHHD
HHHHHHHHCCEEEEEHHHHHHHHHHHHHCCCCHHHHEEEECCCCCCCCCCCCCCCCCCCC
APLDMRMDQDAPLTAYDAVNSWSYEQLVRIFFQYGEEKFSKQIARKIEAYRENKAIETTG
CCCCCCCCCCCCEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ELVELIKEGIPAPARRTGGHPAKRVFQAIRIAVNDELKVFEEALESAIEMVKPGGRVSVI
HHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEE
TFHSLEDRICKTTFKRNSTTPQLPPGLPIIPDEFKPKLKLITRKPILPSDIELEENNRAR
EECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCEECCCCCCC
SAKLRIAEKR
HHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA