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The map label for this gene is mraY

Identifier: 49186763

GI number: 49186763

Start: 3732669

End: 3733643

Strand: Reverse

Name: mraY

Synonym: BAS3764

Alternate gene names: 49186763

Gene position: 3733643-3732669 (Counterclockwise)

Preceding gene: 49186764

Following gene: 49186762

Centisome position: 71.41

GC content: 36.31

Gene sequence:

>975_bases
GTGCTTGAGCAAGGTTTATTAGTAACGGCTGGGGTAGCATTCTTAATTTCTGTTGCCCTTTCGCCATTGTTTATTCCATT
TTTAAGAAAATTAAAGTTCGGACAGAGTATTCGTGATGAGGGACCAAAGTCACATCAAAAAAAATCAGGAACACCGACAA
TGGGTGGTATTGTCATATATGTATCTATGATGGTAACTTCACTTATTATGGCGATTAAGTTTAATCATTTAGGTGCAGAA
GTTTCGTTATTACTATTAGTAACATTTGGTTACGGATTGATTGGGTTTTTAGATGACTACATAAAGGTAGTTAAGAAGAG
AAATCTTGGTTTGACATCAAAACAAAAATTAGTAGGTCAGCTTGTTATTGCAATTGCGTTCTTTTTTATTGGAAAAGGGC
AAGCGTTCCACACATACATTATGATTCCAGGAACGGATGTTAAGTTTGAATTAGGTTGGGCGTATTTTGTACTTGTACTA
TTTATGCTTATTGGTGGATCAAATGCAGTTAACTTAACTGACGGTTTAGATGGTTTATTATCAGGAACAGCTGCTATTGC
ATTTGGAGCTTTTAGTATTATTGCTGTTGCACAAGAGCAATTTGGCGTAGCGATATTCTGTATGGCGGTTGTAGGAGCTG
TACTTGGATTTTTAGTATTCAATGCGAATCCAGCGGAAGTGTTTATGGGAGATACAGGTTCTTTAGCTTTAGGTGGAGCT
ATTGCAGCCGTAGCAATTTTATTAAAACAAGAATTGCTACTTGTAATCATAGGCGGAGTATTCGTAATGGAAACTTTATC
GGTTATTATTCAGGTCATTTCATTTAAAACAACAGGAAAACGTGTCTTTAAAATGAGCCCATTACACCATCATTATGAAT
TATGTGGTTGGTCAGAGTGGCGTGTTGTTGTAACGTTTTGGTCTGTAGGATTTTTATTAGCTGTGTTAGGAATTTATATC
GGGGTGTGGATGTAA

Upstream 100 bases:

>100_bases
GGTAAAGATGTTCATCATTTTGACGATCGTGAAGTCGCTAAAGAAGCAATTACAGAGCGTTTAAACAACGAAGAGTAACA
ACGTGAGAGGAGGACTACAT

Downstream 100 bases:

>100_bases
TTGAAAACTGTAACTGAATTTCAAAATAAAAATATTCTTGTATTAGGCATTGCAAAAAGTGGTTATGCAGCAGCTACATT
GCTACAAAAGTTAGGGGCAA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIYVSMMVTSLIMAIKFNHLGAE
VSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQLVIAIAFFFIGKGQAFHTYIMIPGTDVKFELGWAYFVLVL
FMLIGGSNAVNLTDGLDGLLSGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAEVFMGDTGSLALGGA
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEWRVVVTFWSVGFLLAVLGIYI
GVWM

Sequences:

>Translated_324_residues
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIYVSMMVTSLIMAIKFNHLGAE
VSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQLVIAIAFFFIGKGQAFHTYIMIPGTDVKFELGWAYFVLVL
FMLIGGSNAVNLTDGLDGLLSGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAEVFMGDTGSLALGGA
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEWRVVVTFWSVGFLLAVLGIYI
GVWM
>Mature_324_residues
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIYVSMMVTSLIMAIKFNHLGAE
VSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQLVIAIAFFFIGKGQAFHTYIMIPGTDVKFELGWAYFVLVL
FMLIGGSNAVNLTDGLDGLLSGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAEVFMGDTGSLALGGA
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEWRVVVTFWSVGFLLAVLGIYI
GVWM

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=326, Percent_Identity=47.239263803681, Blast_Score=256, Evalue=1e-69,
Organism=Escherichia coli, GI1790218, Length=206, Percent_Identity=29.126213592233, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_BACAA (C3P683)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868149.1
- EnsemblBacteria:   EBBACT00000124954
- GeneID:   7853005
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4078
- GeneTree:   EBGT00050000001191
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 34941; Mature: 34941

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x155557b4)-; HASH(0x157f6814)-; HASH(0x1568dfc4)-; HASH(0x14dcce38)-; HASH(0x1581d2d0)-; HASH(0x154abf6c)-; HASH(0x15586c94)-; HASH(0x14bfd7dc)-; HASH(0x15fb6174)-; HASH(0x158c16cc)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHCCCCCCCCHHHHHHH
VSMMVTSLIMAIKFNHLGAEVSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LVIAIAFFFIGKGQAFHTYIMIPGTDVKFELGWAYFVLVLFMLIGGSNAVNLTDGLDGLL
HHHHHHHHHHCCCCEEEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCEECCCCHHHHH
SGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAEVFMGDTGSLALGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHCCCCCH
RVVVTFWSVGFLLAVLGIYIGVWM
HHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHCCCCCCCCHHHHHHH
VSMMVTSLIMAIKFNHLGAEVSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLVGQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LVIAIAFFFIGKGQAFHTYIMIPGTDVKFELGWAYFVLVLFMLIGGSNAVNLTDGLDGLL
HHHHHHHHHHCCCCEEEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCEECCCCHHHHH
SGTAAIAFGAFSIIAVAQEQFGVAIFCMAVVGAVLGFLVFNANPAEVFMGDTGSLALGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHCCCCCH
RVVVTFWSVGFLLAVLGIYIGVWM
HHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA