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The map label for this gene is asd [H]

Identifier: 49186651

GI number: 49186651

Start: 3614426

End: 3615475

Strand: Reverse

Name: asd [H]

Synonym: BAS3652

Alternate gene names: 49186651

Gene position: 3615475-3614426 (Counterclockwise)

Preceding gene: 49186652

Following gene: 49186650

Centisome position: 69.15

GC content: 37.71

Gene sequence:

>1050_bases
GTGATGGAAAAGCAAAAAACTTTTCATGTCGCTGTAGTTGGAGCAACCGGCGCAGTTGGTGAACAAATGTTAAATACTTT
AGAGAAACGAGAATTTCCAATCGGGAAGTTAACGTTACTTTCATCTAAACGATCTGCAGGTAAGAAACTTGTATTTAAAG
GCGAAGAATTTACAGTTCAAGAGGCAACTCCTGAAAGTTTTGAAGGAGTAGATATCGCACTATTTAGTGCAGGTGGATCT
GTATCAAAACAATTAGCGCCAGAAGCAGCAAAGCGCGGTGCGATTGTTGTTGATAATACAAGTGCATTCCGTATGACAGA
AAACGTGCCACTTGTTGTACCTGAAGTAAATGAAAACGACTTAAAAGAACATAATGGTATTATTGCAAATCCAAACTGTT
CTACAATTCAAATGGTAGTAGCTCTTGAGCCAGTTCGTCAGCAATATGGTTTAAAACGAGTAATCGTTTCCACATATCAA
GCTGTATCAGGTGCTGGTGCGGCAGCGATTGAAGAACTTCATGAACAATCACAAGCAATCTTAAATGGCGAAGAAGTGAA
GGCGAATGTTTTACCTGTATCAGGTGATAAGAAACATTTTCCAATTGCTTTCAACGCGATTCCACAGATTGATAAGTTCC
AAGATAATGGATTTACGTTTGAAGAAATGAAAATGATTAATGAAACGAAAAAAATTATGCATATGCCTGAATTAGAAGTA
GCGGCAACATGTGTACGTTTACCAGTTGTATCAGGTCACTCTGAGTCTGTTTACATTGAAGTAGAAAAAGAAGGCGTAAC
AGTAGAAGAATTAAAGAGCTTACTTGCAAATGCGGAAGGTATCGTTCTACAAGATAATCCAGAAGAGCAGCTATATCCAA
TGCCAGCTACTGCAGTAGGTAAAAACGAAGTATTCGTGGGAAGAATTCGTAAAGATTTAAATAACGATAAAGGATTCCAT
CTTTGGGTCGTATCTGATAACTTATTAAAAGGCGCAGCATGGAATTCTGTTCAAATTGCAGAGCGCTTAGTAAAATTACA
ATTAGTGTAA

Upstream 100 bases:

>100_bases
GTAGAATATGATAAAATTAACGTTATTAAGATTAGAAGGGGTATTGTATACTCCTTCTGATTCTAAGTTATAGAAGGATT
GGTATCTAGAAAGGGGCATA

Downstream 100 bases:

>100_bases
GCGGCTAAGAGAAGGTGCAAAATATGAAAATTATTGTTCAAAAATTTGGTGGTACATCTGTACGTGATGAAAATGGACGT
AAGCATGCGCTTCATCATAT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MMEKQKTFHVAVVGATGAVGEQMLNTLEKREFPIGKLTLLSSKRSAGKKLVFKGEEFTVQEATPESFEGVDIALFSAGGS
VSKQLAPEAAKRGAIVVDNTSAFRMTENVPLVVPEVNENDLKEHNGIIANPNCSTIQMVVALEPVRQQYGLKRVIVSTYQ
AVSGAGAAAIEELHEQSQAILNGEEVKANVLPVSGDKKHFPIAFNAIPQIDKFQDNGFTFEEMKMINETKKIMHMPELEV
AATCVRLPVVSGHSESVYIEVEKEGVTVEELKSLLANAEGIVLQDNPEEQLYPMPATAVGKNEVFVGRIRKDLNNDKGFH
LWVVSDNLLKGAAWNSVQIAERLVKLQLV

Sequences:

>Translated_349_residues
MMEKQKTFHVAVVGATGAVGEQMLNTLEKREFPIGKLTLLSSKRSAGKKLVFKGEEFTVQEATPESFEGVDIALFSAGGS
VSKQLAPEAAKRGAIVVDNTSAFRMTENVPLVVPEVNENDLKEHNGIIANPNCSTIQMVVALEPVRQQYGLKRVIVSTYQ
AVSGAGAAAIEELHEQSQAILNGEEVKANVLPVSGDKKHFPIAFNAIPQIDKFQDNGFTFEEMKMINETKKIMHMPELEV
AATCVRLPVVSGHSESVYIEVEKEGVTVEELKSLLANAEGIVLQDNPEEQLYPMPATAVGKNEVFVGRIRKDLNNDKGFH
LWVVSDNLLKGAAWNSVQIAERLVKLQLV
>Mature_349_residues
MMEKQKTFHVAVVGATGAVGEQMLNTLEKREFPIGKLTLLSSKRSAGKKLVFKGEEFTVQEATPESFEGVDIALFSAGGS
VSKQLAPEAAKRGAIVVDNTSAFRMTENVPLVVPEVNENDLKEHNGIIANPNCSTIQMVVALEPVRQQYGLKRVIVSTYQ
AVSGAGAAAIEELHEQSQAILNGEEVKANVLPVSGDKKHFPIAFNAIPQIDKFQDNGFTFEEMKMINETKKIMHMPELEV
AATCVRLPVVSGHSESVYIEVEKEGVTVEELKSLLANAEGIVLQDNPEEQLYPMPATAVGKNEVFVGRIRKDLNNDKGFH
LWVVSDNLLKGAAWNSVQIAERLVKLQLV

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=345, Percent_Identity=34.7826086956522, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1789841, Length=357, Percent_Identity=29.9719887955182, Blast_Score=112, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6320362, Length=396, Percent_Identity=27.5252525252525, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38163; Mature: 38163

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEKQKTFHVAVVGATGAVGEQMLNTLEKREFPIGKLTLLSSKRSAGKKLVFKGEEFTVQ
CCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCEEEEE
EATPESFEGVDIALFSAGGSVSKQLAPEAAKRGAIVVDNTSAFRMTENVPLVVPEVNEND
CCCCCCCCCEEEEEEECCCCCHHHHCHHHHHCCEEEEECCCEEEEECCCCEEEECCCCCH
LKEHNGIIANPNCSTIQMVVALEPVRQQYGLKRVIVSTYQAVSGAGAAAIEELHEQSQAI
HHHCCCEEECCCCCEEEEEEEHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LNGEEVKANVLPVSGDKKHFPIAFNAIPQIDKFQDNGFTFEEMKMINETKKIMHMPELEV
CCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHH
AATCVRLPVVSGHSESVYIEVEKEGVTVEELKSLLANAEGIVLQDNPEEQLYPMPATAVG
HHHHHEEEEECCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEECCCCCHHEECCCCHHCC
KNEVFVGRIRKDLNNDKGFHLWVVSDNLLKGAAWNSVQIAERLVKLQLV
CCCEEHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHEECC
>Mature Secondary Structure
MMEKQKTFHVAVVGATGAVGEQMLNTLEKREFPIGKLTLLSSKRSAGKKLVFKGEEFTVQ
CCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCEEEEE
EATPESFEGVDIALFSAGGSVSKQLAPEAAKRGAIVVDNTSAFRMTENVPLVVPEVNEND
CCCCCCCCCEEEEEEECCCCCHHHHCHHHHHCCEEEEECCCEEEEECCCCEEEECCCCCH
LKEHNGIIANPNCSTIQMVVALEPVRQQYGLKRVIVSTYQAVSGAGAAAIEELHEQSQAI
HHHCCCEEECCCCCEEEEEEEHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LNGEEVKANVLPVSGDKKHFPIAFNAIPQIDKFQDNGFTFEEMKMINETKKIMHMPELEV
CCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHH
AATCVRLPVVSGHSESVYIEVEKEGVTVEELKSLLANAEGIVLQDNPEEQLYPMPATAVG
HHHHHEEEEECCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEECCCCCHHEECCCCHHCC
KNEVFVGRIRKDLNNDKGFHLWVVSDNLLKGAAWNSVQIAERLVKLQLV
CCCEEHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377; 8345520 [H]