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The map label for this gene is yueD [H]

Identifier: 49186346

GI number: 49186346

Start: 3311406

End: 3312155

Strand: Direct

Name: yueD [H]

Synonym: BAS3341

Alternate gene names: 49186346

Gene position: 3311406-3312155 (Clockwise)

Preceding gene: 49186344

Following gene: 49186353

Centisome position: 63.33

GC content: 35.33

Gene sequence:

>750_bases
ATGCGCTATGTTATCATAACAGGAACTTCACAAGGTTTAGGTGAGGCTATCGCCGCTCAATTGTTAGAAGAAAACACGAG
TATTATCTCTATTTCTAGAAGAGAAAATAAAGAGCTTACGAAACTCGCAGAACAATATAATAGCAATTGTGTTTTCCACT
CCCTAGATCTTCAAGATGTACATAATTTAGAAACGAATTTTAACGAAATCATTTCATCTATTCAAGAAGACACTGTATCA
TCTATTCATTTAATTAATAACGCTGGTACACTCGCACCTATGAAGCCGATTGAAAAAGCTGAAAGCGAACAATTCATTAC
AAACGTTCACATTAATTTACTTGCTCCAATGATTCTTACATCTACTTTCATGAAACATACAAAAGACTGGAAAGTAGATA
AACGCGTTATAAATATTTCATCTGGCGCAGGAAAAAATCCTTATTTCGGATGGGGCGCTTATTGTACGACGAAAGCTGGT
GTAAATATGTTTACACAATGCGTAGCGACTGAAGAAGTGGAAAAAGAATATCCCGTAAAAATCGTCGCTTTTGCGCCTGG
TGTTGTTGACACTAATATGCAAGCACAAATTCGTGAAACAAATAAAGAAGACTTCACAAATTTAGACCGCTTCATCACAT
TAAAAGAAGAAGGAAAACTATTATCACCTGAATATGTAGCAAAAGCTATTCGTAACTTACTAGAAACTGAAGACTTCCCT
CAAGGCGAGGTTATTAGAATTGATGAATAA

Upstream 100 bases:

>100_bases
ATTTATAGTAAAAAGTGCTCTATACTATAAAATGTAGACAAACTATGCAATGTACTTTGTCCAACAAAATCCCGCACGTA
CGAGAGGAGCTTACTACACT

Downstream 100 bases:

>100_bases
CAAAAAGGCGTGCTAAATTAGCACGCCTTTTTGTTCTACTTCTCTAAAAATATAAGCATAGACTCCGCAATTTGTTCATA
ACCAATTTCTTGGTAAATTT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MRYVIITGTSQGLGEAIAAQLLEENTSIISISRRENKELTKLAEQYNSNCVFHSLDLQDVHNLETNFNEIISSIQEDTVS
SIHLINNAGTLAPMKPIEKAESEQFITNVHINLLAPMILTSTFMKHTKDWKVDKRVINISSGAGKNPYFGWGAYCTTKAG
VNMFTQCVATEEVEKEYPVKIVAFAPGVVDTNMQAQIRETNKEDFTNLDRFITLKEEGKLLSPEYVAKAIRNLLETEDFP
QGEVIRIDE

Sequences:

>Translated_249_residues
MRYVIITGTSQGLGEAIAAQLLEENTSIISISRRENKELTKLAEQYNSNCVFHSLDLQDVHNLETNFNEIISSIQEDTVS
SIHLINNAGTLAPMKPIEKAESEQFITNVHINLLAPMILTSTFMKHTKDWKVDKRVINISSGAGKNPYFGWGAYCTTKAG
VNMFTQCVATEEVEKEYPVKIVAFAPGVVDTNMQAQIRETNKEDFTNLDRFITLKEEGKLLSPEYVAKAIRNLLETEDFP
QGEVIRIDE
>Mature_249_residues
MRYVIITGTSQGLGEAIAAQLLEENTSIISISRRENKELTKLAEQYNSNCVFHSLDLQDVHNLETNFNEIISSIQEDTVS
SIHLINNAGTLAPMKPIEKAESEQFITNVHINLLAPMILTSTFMKHTKDWKVDKRVINISSGAGKNPYFGWGAYCTTKAG
VNMFTQCVATEEVEKEYPVKIVAFAPGVVDTNMQAQIRETNKEDFTNLDRFITLKEEGKLLSPEYVAKAIRNLLETEDFP
QGEVIRIDE

Specific function: Reduces benzil stereospecifically to (S)-benzoin. Can also reduces 1-phenyl-1,2-propanedione, 1,4-naphthoquinone, 1-(4- methyl-phenyl)-2-phenyl-ethane-1,2-dione, 1-(4-fluoro-phenyl)-2- phenyl-ethane-1,2-dione, methyl benzoylformate, p- nitrobenzaldehyde i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4507185, Length=254, Percent_Identity=29.1338582677165, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI150247226, Length=223, Percent_Identity=26.9058295964126, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=24.2798353909465, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787820, Length=195, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=259, Percent_Identity=31.2741312741313, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=27.734375, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=193, Percent_Identity=25.3886010362694, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=243, Percent_Identity=30.8641975308642, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322226, Length=246, Percent_Identity=27.6422764227642, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=28.4584980237154, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24640597, Length=252, Percent_Identity=25.3968253968254, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24643142, Length=194, Percent_Identity=24.7422680412371, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357041, Length=195, Percent_Identity=29.2307692307692, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27975; Mature: 27975

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVIITGTSQGLGEAIAAQLLEENTSIISISRRENKELTKLAEQYNSNCVFHSLDLQDV
CEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCEEEECCHHHH
HNLETNFNEIISSIQEDTVSSIHLINNAGTLAPMKPIEKAESEQFITNVHINLLAPMILT
HHHHCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
STFMKHTKDWKVDKRVINISSGAGKNPYFGWGAYCTTKAGVNMFTQCVATEEVEKEYPVK
HHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEE
IVAFAPGVVDTNMQAQIRETNKEDFTNLDRFITLKEEGKLLSPEYVAKAIRNLLETEDFP
EEEECCCEECCCCHHHHHHCCHHHHCCHHHEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
QGEVIRIDE
CCCEEEECC
>Mature Secondary Structure
MRYVIITGTSQGLGEAIAAQLLEENTSIISISRRENKELTKLAEQYNSNCVFHSLDLQDV
CEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCEEEECCHHHH
HNLETNFNEIISSIQEDTVSSIHLINNAGTLAPMKPIEKAESEQFITNVHINLLAPMILT
HHHHCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
STFMKHTKDWKVDKRVINISSGAGKNPYFGWGAYCTTKAGVNMFTQCVATEEVEKEYPVK
HHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEE
IVAFAPGVVDTNMQAQIRETNKEDFTNLDRFITLKEEGKLLSPEYVAKAIRNLLETEDFP
EEEECCCEECCCCHHHHHHCCHHHHCCHHHEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
QGEVIRIDE
CCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11745140; 11796169 [H]