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The map label for this gene is ag45 [H]

Identifier: 49186275

GI number: 49186275

Start: 3235886

End: 3237211

Strand: Direct

Name: ag45 [H]

Synonym: BAS3270

Alternate gene names: 49186275

Gene position: 3235886-3237211 (Clockwise)

Preceding gene: 49186269

Following gene: 49186277

Centisome position: 61.89

GC content: 36.8

Gene sequence:

>1326_bases
TTGGAACAATCAGCACATGAAGTAGCAAATTGGCAATATTATTTTGCAATTGCCGTATTTTTAGTCACGTACGGATTTAT
TATTTCTGAGAAATTGAATCGTGCTGTAATCGCACTATTCGGCGCTGCTATTATGATTATTTTTGGAGTTGTAGATTTAC
ATACTGCTTTCACATCACATATTCAATGGGAAACGATTACCCTTTTAATTGGGATGATGATTCTCGTACATATTACGAGT
CAATCAGGCGTGTTTGAGTTTGTGGCCATTAAAGCAGCAAAAGCAGCTGGCGGAAAACCAATCCGTATATTATTATTACT
ATCCTTATTAACTGCTGGCGGATCAGCATTTTTGGACAACGTAACAACAGTCTTATTAATCGTCCCTGTTACACTGTCCA
TTACACGTATTTTAAAAGTAAATCCTGTTCCTTATTTACTTTCAGAAGTACTATTTTCAAATATAGGCGGAACAGCAACA
TTAATCGGTGACCCACCTAATATTATGATTGGATCAGCAAATAAGCATTTAGACTTTAATGCCTTTTTACTAAACTTAGC
TCCAATCGTAATTATTATTTCTATCGTTACACTTGGCATTATTTACTTCCTGTATCGCAACAAACTAAAAACAACAACTG
AACAAATTAATATATTAATGGGATTAAACGAAAAAGATTATATTAAAGATCACAGCCTCCTTTTAAAATCCATTTCGGTT
TTAGGACTAACTATTTTAGGCTTTATACTTCATTCGATTATTCATGTAGACGCTGCCGTTATCGCGATGACAGGCGCTAC
ACTTCTTATGCTAATTGGAGTAAAAGACCATGATATTGAAGATGTATTTGCCCACGTTGAATGGGTAACCATCTTCTTCT
TCGCCGGACTATTCGTCCTCGTTGGCGGTTTAATTGATATCGGACTTATTTCTTCACTCGCAAAAGAAGTAATCGACGTA
ACAAACGGGGATATCGGTTTCGCTGCGATACTTATTTTATGGGTATCGGGCATCGCATCTGCGACCATTGACAATATCCC
ATTTGTCGCAACAATGATCCCGCTTATTCAAGATTTAGCTACAGGACTCGGACTATCTGTCGATTCCCCGCAAATCGAAG
TATTATGGTGGGCTTTATCACTTGGAGCTTGCTTAGGAGGAAACGGAACATTAATCGGAGCATCCGCAAACGTAGTCGTT
GCTGGTATTGCAAAACGTGAAGGGCATGAATTCTCTTATATGGACTTCTTAAAAATTGGTTTTCCGTTAACAATTATTGC
ATTACTATTATCACACGCTTATATATATTTACGTTATTTAATGTAA

Upstream 100 bases:

>100_bases
TTCTTTCTTTTTTGAATTTGCTACAATATATTTTATCCCGTATTCATATAACGGGATACATTTTGACAATTGAATACATA
CTTTGAAGAAGGTGACATGA

Downstream 100 bases:

>100_bases
AAGTTGTATTGCATGAAATTATATCGTCACATACAAAAGGTTTGCAGCAAAGTGCTGCAAACCTTTTTTCATCACCAAAA
TATACCGATAATTGCTAAAC

Product: arsenical pump family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MEQSAHEVANWQYYFAIAVFLVTYGFIISEKLNRAVIALFGAAIMIIFGVVDLHTAFTSHIQWETITLLIGMMILVHITS
QSGVFEFVAIKAAKAAGGKPIRILLLLSLLTAGGSAFLDNVTTVLLIVPVTLSITRILKVNPVPYLLSEVLFSNIGGTAT
LIGDPPNIMIGSANKHLDFNAFLLNLAPIVIIISIVTLGIIYFLYRNKLKTTTEQINILMGLNEKDYIKDHSLLLKSISV
LGLTILGFILHSIIHVDAAVIAMTGATLLMLIGVKDHDIEDVFAHVEWVTIFFFAGLFVLVGGLIDIGLISSLAKEVIDV
TNGDIGFAAILILWVSGIASATIDNIPFVATMIPLIQDLATGLGLSVDSPQIEVLWWALSLGACLGGNGTLIGASANVVV
AGIAKREGHEFSYMDFLKIGFPLTIIALLLSHAYIYLRYLM

Sequences:

>Translated_441_residues
MEQSAHEVANWQYYFAIAVFLVTYGFIISEKLNRAVIALFGAAIMIIFGVVDLHTAFTSHIQWETITLLIGMMILVHITS
QSGVFEFVAIKAAKAAGGKPIRILLLLSLLTAGGSAFLDNVTTVLLIVPVTLSITRILKVNPVPYLLSEVLFSNIGGTAT
LIGDPPNIMIGSANKHLDFNAFLLNLAPIVIIISIVTLGIIYFLYRNKLKTTTEQINILMGLNEKDYIKDHSLLLKSISV
LGLTILGFILHSIIHVDAAVIAMTGATLLMLIGVKDHDIEDVFAHVEWVTIFFFAGLFVLVGGLIDIGLISSLAKEVIDV
TNGDIGFAAILILWVSGIASATIDNIPFVATMIPLIQDLATGLGLSVDSPQIEVLWWALSLGACLGGNGTLIGASANVVV
AGIAKREGHEFSYMDFLKIGFPLTIIALLLSHAYIYLRYLM
>Mature_441_residues
MEQSAHEVANWQYYFAIAVFLVTYGFIISEKLNRAVIALFGAAIMIIFGVVDLHTAFTSHIQWETITLLIGMMILVHITS
QSGVFEFVAIKAAKAAGGKPIRILLLLSLLTAGGSAFLDNVTTVLLIVPVTLSITRILKVNPVPYLLSEVLFSNIGGTAT
LIGDPPNIMIGSANKHLDFNAFLLNLAPIVIIISIVTLGIIYFLYRNKLKTTTEQINILMGLNEKDYIKDHSLLLKSISV
LGLTILGFILHSIIHVDAAVIAMTGATLLMLIGVKDHDIEDVFAHVEWVTIFFFAGLFVLVGGLIDIGLISSLAKEVIDV
TNGDIGFAAILILWVSGIASATIDNIPFVATMIPLIQDLATGLGLSVDSPQIEVLWWALSLGACLGGNGTLIGASANVVV
AGIAKREGHEFSYMDFLKIGFPLTIIALLLSHAYIYLRYLM

Specific function: Unknown

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Homo sapiens, GI157266326, Length=503, Percent_Identity=35.1888667992048, Blast_Score=245, Evalue=5e-65,
Organism=Drosophila melanogaster, GI28574683, Length=497, Percent_Identity=33.1991951710262, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI28574681, Length=497, Percent_Identity=33.1991951710262, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI28574685, Length=497, Percent_Identity=33.1991951710262, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI28574678, Length=497, Percent_Identity=33.1991951710262, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24581759, Length=497, Percent_Identity=33.1991951710262, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI19920704, Length=497, Percent_Identity=33.1991951710262, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI221472711, Length=492, Percent_Identity=28.8617886178862, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24581764, Length=492, Percent_Identity=28.8617886178862, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI45550608, Length=471, Percent_Identity=32.6963906581741, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI85724998, Length=454, Percent_Identity=26.431718061674, Blast_Score=154, Evalue=8e-38,
Organism=Drosophila melanogaster, GI62484377, Length=454, Percent_Identity=26.431718061674, Blast_Score=154, Evalue=8e-38,
Organism=Drosophila melanogaster, GI24656008, Length=463, Percent_Identity=26.5658747300216, Blast_Score=122, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 47632; Mature: 47632

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQSAHEVANWQYYFAIAVFLVTYGFIISEKLNRAVIALFGAAIMIIFGVVDLHTAFTSH
CCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQWETITLLIGMMILVHITSQSGVFEFVAIKAAKAAGGKPIRILLLLSLLTAGGSAFLDN
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHH
VTTVLLIVPVTLSITRILKVNPVPYLLSEVLFSNIGGTATLIGDPPNIMIGSANKHLDFN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCHH
AFLLNLAPIVIIISIVTLGIIYFLYRNKLKTTTEQINILMGLNEKDYIKDHSLLLKSISV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHH
LGLTILGFILHSIIHVDAAVIAMTGATLLMLIGVKDHDIEDVFAHVEWVTIFFFAGLFVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
VGGLIDIGLISSLAKEVIDVTNGDIGFAAILILWVSGIASATIDNIPFVATMIPLIQDLA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TGLGLSVDSPQIEVLWWALSLGACLGGNGTLIGASANVVVAGIAKREGHEFSYMDFLKIG
HHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEHHCCCCCCHHHHHHHHC
FPLTIIALLLSHAYIYLRYLM
CHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEQSAHEVANWQYYFAIAVFLVTYGFIISEKLNRAVIALFGAAIMIIFGVVDLHTAFTSH
CCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQWETITLLIGMMILVHITSQSGVFEFVAIKAAKAAGGKPIRILLLLSLLTAGGSAFLDN
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHH
VTTVLLIVPVTLSITRILKVNPVPYLLSEVLFSNIGGTATLIGDPPNIMIGSANKHLDFN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCHH
AFLLNLAPIVIIISIVTLGIIYFLYRNKLKTTTEQINILMGLNEKDYIKDHSLLLKSISV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHH
LGLTILGFILHSIIHVDAAVIAMTGATLLMLIGVKDHDIEDVFAHVEWVTIFFFAGLFVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
VGGLIDIGLISSLAKEVIDVTNGDIGFAAILILWVSGIASATIDNIPFVATMIPLIQDLA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TGLGLSVDSPQIEVLWWALSLGACLGGNGTLIGASANVVVAGIAKREGHEFSYMDFLKIG
HHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEHHCCCCCCHHHHHHHHC
FPLTIIALLLSHAYIYLRYLM
CHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]