Click here to switch to the map view.

The map label for this gene is mhpC [C]

Identifier: 49186103

GI number: 49186103

Start: 3078041

End: 3078943

Strand: Reverse

Name: mhpC [C]

Synonym: BAS3098

Alternate gene names: 49186103

Gene position: 3078943-3078041 (Counterclockwise)

Preceding gene: 49186107

Following gene: 49186102

Centisome position: 58.89

GC content: 36.21

Gene sequence:

>903_bases
ATGATTAAGCCTGCAACAATGGAGTTTGTTTCACTATCGAACGGAGAAACGATTGCGTATCAGGAAGTTGGAAGGCAAAA
TGCAGAAATTCTTGTACTCATTCACGGAAACATGACATCGTCACAACACTTTGATTTAGTTATTGAAAAGCTGCAAGATC
AATACCATATTTACGCTCTAGATTTAAGAGGATTTGGTCAATCAACATATAATAAAGCGATAGATTCAATACAAGACTTT
GCAGAAGATGTAAAACTATTTATCGACGGGTTAAAACTAGAGAAATTTTCATTAATGGGCTGGTCAATGGGCGGTGGTGT
TGCGATGCAATTTACAGCGAATCATCCAACGTTTGTCGAAAAGTTAATTTTAGTAGAATCAGTAGGAATGAAGGGCTACC
CAATCTTTAAAAAAGATATAAACGGGCAGCCGATTGTATCTAGTTTAGTTAAGACGAAAGAAGAAATTGCGCAAGATCCT
GTACAAATTGCACCAGTGTTAGATGCGATAAAAAATATGAATAAACTATATTACCGTACAGTATGGAACTTGTTAATATA
TACACATAATCAACCTGAACCAGATCGCTATGAAAAGTATTTAGACGATATGTTAACGCAGCGTAATTTCGTAGATGTGA
ATTATGCGCTCATTACATTTAATATTTCGGATGAACATAACGGGGTTGTAGAGGGAAATAAGCAAATTCATCGTATTAAA
GCTCCGACACTCGTCATACAAGGCGACAGAGATTATGTCGTACCGCAAGTAGTGGGTGAGGAGTTAGTAAAACATTTGCC
GAATGCTGAATTACAATTGTTAGAAGATTGCGGTCATTCTCCGTTTATTGATTGTTTAGATGTATTTATAAAGCATGTAG
AGGATTGGTTAGAAGGTAAGTAG

Upstream 100 bases:

>100_bases
AATTTCGTATAGCTTTTATGTTGAGAACATACATTCTGCATGTTATTCTTTAATTAAGTAAAGAATTATCTTTCTATTAA
AAAGAATGGGGGAACTTGTG

Downstream 100 bases:

>100_bases
GGTGAGGAAGAAGTTAGATGACATGTGTCTAGCTTCTTTTTTGTGGAAAAATGAAAATTATTTCATCCACTAGTCCTTTC
TTATTCCATAGTAAACAATA

Product: alpha/beta fold family hydrolase

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MIKPATMEFVSLSNGETIAYQEVGRQNAEILVLIHGNMTSSQHFDLVIEKLQDQYHIYALDLRGFGQSTYNKAIDSIQDF
AEDVKLFIDGLKLEKFSLMGWSMGGGVAMQFTANHPTFVEKLILVESVGMKGYPIFKKDINGQPIVSSLVKTKEEIAQDP
VQIAPVLDAIKNMNKLYYRTVWNLLIYTHNQPEPDRYEKYLDDMLTQRNFVDVNYALITFNISDEHNGVVEGNKQIHRIK
APTLVIQGDRDYVVPQVVGEELVKHLPNAELQLLEDCGHSPFIDCLDVFIKHVEDWLEGK

Sequences:

>Translated_300_residues
MIKPATMEFVSLSNGETIAYQEVGRQNAEILVLIHGNMTSSQHFDLVIEKLQDQYHIYALDLRGFGQSTYNKAIDSIQDF
AEDVKLFIDGLKLEKFSLMGWSMGGGVAMQFTANHPTFVEKLILVESVGMKGYPIFKKDINGQPIVSSLVKTKEEIAQDP
VQIAPVLDAIKNMNKLYYRTVWNLLIYTHNQPEPDRYEKYLDDMLTQRNFVDVNYALITFNISDEHNGVVEGNKQIHRIK
APTLVIQGDRDYVVPQVVGEELVKHLPNAELQLLEDCGHSPFIDCLDVFIKHVEDWLEGK
>Mature_300_residues
MIKPATMEFVSLSNGETIAYQEVGRQNAEILVLIHGNMTSSQHFDLVIEKLQDQYHIYALDLRGFGQSTYNKAIDSIQDF
AEDVKLFIDGLKLEKFSLMGWSMGGGVAMQFTANHPTFVEKLILVESVGMKGYPIFKKDINGQPIVSSLVKTKEEIAQDP
VQIAPVLDAIKNMNKLYYRTVWNLLIYTHNQPEPDRYEKYLDDMLTQRNFVDVNYALITFNISDEHNGVVEGNKQIHRIK
APTLVIQGDRDYVVPQVVGEELVKHLPNAELQLLEDCGHSPFIDCLDVFIKHVEDWLEGK

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 34161; Mature: 34161

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKPATMEFVSLSNGETIAYQEVGRQNAEILVLIHGNMTSSQHFDLVIEKLQDQYHIYAL
CCCCCCCCEEECCCCCEEEHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEE
DLRGFGQSTYNKAIDSIQDFAEDVKLFIDGLKLEKFSLMGWSMGGGVAMQFTANHPTFVE
EECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCEEEEEECCCHHHHH
KLILVESVGMKGYPIFKKDINGQPIVSSLVKTKEEIAQDPVQIAPVLDAIKNMNKLYYRT
HHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VWNLLIYTHNQPEPDRYEKYLDDMLTQRNFVDVNYALITFNISDEHNGVVEGNKQIHRIK
HHHHHEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCEECCCCEEEEEE
APTLVIQGDRDYVVPQVVGEELVKHLPNAELQLLEDCGHSPFIDCLDVFIKHVEDWLEGK
CCEEEEECCCCEECHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKPATMEFVSLSNGETIAYQEVGRQNAEILVLIHGNMTSSQHFDLVIEKLQDQYHIYAL
CCCCCCCCEEECCCCCEEEHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEE
DLRGFGQSTYNKAIDSIQDFAEDVKLFIDGLKLEKFSLMGWSMGGGVAMQFTANHPTFVE
EECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCEEEEEECCCHHHHH
KLILVESVGMKGYPIFKKDINGQPIVSSLVKTKEEIAQDPVQIAPVLDAIKNMNKLYYRT
HHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VWNLLIYTHNQPEPDRYEKYLDDMLTQRNFVDVNYALITFNISDEHNGVVEGNKQIHRIK
HHHHHEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCEECCCCEEEEEE
APTLVIQGDRDYVVPQVVGEELVKHLPNAELQLLEDCGHSPFIDCLDVFIKHVEDWLEGK
CCEEEEECCCCEECHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]