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The map label for this gene is uvrX [H]

Identifier: 49186058

GI number: 49186058

Start: 3026296

End: 3027561

Strand: Direct

Name: uvrX [H]

Synonym: BAS3053

Alternate gene names: 49186058

Gene position: 3026296-3027561 (Clockwise)

Preceding gene: 49186055

Following gene: 49186059

Centisome position: 57.88

GC content: 33.49

Gene sequence:

>1266_bases
GTGTATGACTATTCAATTTTACCGAATAGAATCATTTTATGTGTTGATCTTCGTAGCTTTTATGCTTCTGTTAGTTGCAT
CAAAATGGGATTAGACCCACTTCATACAAAATTAGCTGTAGTTGGTGATATGAATAGGAATGGATCCATTGTTTTAGCCG
CAACTCCACCTTTAAAAGCAATGGGAGTAAAGAAGTTGGCAAGGCTATACGAGATTCCTCGACAAAAAGATATTCTTATT
GTGAATCCAATTATGGGAACCTATATTAAGTGCTCCAATTACATAACGAAGTTAGCTCTACAATATGTTCCTATTGAAGA
CTTTCATCAATATAGCATCGATGAATTTTTTATGGATATTACCGATAGCATCCATCTATTTGCTCGGAATCCAAATGAAT
TTGCATTACAGTTTAAACGTGAAATATATGAACACACACGAATTGAATGCACAATCGGGATTGCACCTAACCTATTGATG
AGTAAGGTTGCTTTAGATATTGAAGCAAAGAAAAATAAAGACGGAGTCGCTTATTGGACATACGAAGATATACCTACAAA
ATTATGGAGCATACGACCGCTTAGTAAGTTTTGGGGGATTTCGCATAAAACAGAAACAAAATTAAATCAAAAAGGAATAC
ATTCAATTGGTGATTTAGCTAATTATCCTCTTAAATATTTAAAACAAAGTTTCGGCGTGATTGGCGAAGAATTACACTTA
CATAGTAACGGGATTGATTTTAGTCGAATTTCAGAGAAATATGTTCCGGTTACAACTTCTATAGGAAAAAGCCAAATTTT
AATGCGTGATTATACAATAGAAGAATTTCCGATTATCCTACTGGAACATACCGAAGAAGTTTGCTATCGATTAAGACAAC
AAAACAAACTTGCTCAAACCGTTCAATTTTCAATTGGATATAGTAAAAGTTATTCGGGTGGCTTTAGCAAAACACATACC
TTAAGCCGTCCCACTAACTTAACCATGGACATTTATCAAGTTTGTCTATATTTTCTAAATCAACAATATACTGGAGAACC
AATTAGAAGTATTACTATTTCTCTAACAAAACTAATTGGTGAAGGAGAAGAACAAATTTCCCTTTTTGATAACATCATAC
AACGAGAAAAAGAAATAAAGCTAACGAAAGTAATGGATGAAATACGCACAAAGTTTGGAAAAAATAGCATATTAAGAGGA
ATTTCCTATACAAATAATGCAACAGCAAGATACAGAAACACACTGTTAGGGGGACACAAAGCATGA

Upstream 100 bases:

>100_bases
TAATTAAATATTTTTTCAAAAACCACTTCATAAAAGAACATAAGTTCATTTATAATAATAAAAGGAACAAACGTCCTTAT
TTTTATTAGGAGGAGTTATA

Downstream 100 bases:

>100_bases
ACAACGCTAATATGCCAAAAGGTAGAGGAATGATAAAATGGACGCCGTTTGCAGCAATGCCAGAACAATTCGTCGGAATA
CGTGAAATGATCAAAGAGAA

Product: impB/mucB/samB family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MYDYSILPNRIILCVDLRSFYASVSCIKMGLDPLHTKLAVVGDMNRNGSIVLAATPPLKAMGVKKLARLYEIPRQKDILI
VNPIMGTYIKCSNYITKLALQYVPIEDFHQYSIDEFFMDITDSIHLFARNPNEFALQFKREIYEHTRIECTIGIAPNLLM
SKVALDIEAKKNKDGVAYWTYEDIPTKLWSIRPLSKFWGISHKTETKLNQKGIHSIGDLANYPLKYLKQSFGVIGEELHL
HSNGIDFSRISEKYVPVTTSIGKSQILMRDYTIEEFPIILLEHTEEVCYRLRQQNKLAQTVQFSIGYSKSYSGGFSKTHT
LSRPTNLTMDIYQVCLYFLNQQYTGEPIRSITISLTKLIGEGEEQISLFDNIIQREKEIKLTKVMDEIRTKFGKNSILRG
ISYTNNATARYRNTLLGGHKA

Sequences:

>Translated_421_residues
MYDYSILPNRIILCVDLRSFYASVSCIKMGLDPLHTKLAVVGDMNRNGSIVLAATPPLKAMGVKKLARLYEIPRQKDILI
VNPIMGTYIKCSNYITKLALQYVPIEDFHQYSIDEFFMDITDSIHLFARNPNEFALQFKREIYEHTRIECTIGIAPNLLM
SKVALDIEAKKNKDGVAYWTYEDIPTKLWSIRPLSKFWGISHKTETKLNQKGIHSIGDLANYPLKYLKQSFGVIGEELHL
HSNGIDFSRISEKYVPVTTSIGKSQILMRDYTIEEFPIILLEHTEEVCYRLRQQNKLAQTVQFSIGYSKSYSGGFSKTHT
LSRPTNLTMDIYQVCLYFLNQQYTGEPIRSITISLTKLIGEGEEQISLFDNIIQREKEIKLTKVMDEIRTKFGKNSILRG
ISYTNNATARYRNTLLGGHKA
>Mature_421_residues
MYDYSILPNRIILCVDLRSFYASVSCIKMGLDPLHTKLAVVGDMNRNGSIVLAATPPLKAMGVKKLARLYEIPRQKDILI
VNPIMGTYIKCSNYITKLALQYVPIEDFHQYSIDEFFMDITDSIHLFARNPNEFALQFKREIYEHTRIECTIGIAPNLLM
SKVALDIEAKKNKDGVAYWTYEDIPTKLWSIRPLSKFWGISHKTETKLNQKGIHSIGDLANYPLKYLKQSFGVIGEELHL
HSNGIDFSRISEKYVPVTTSIGKSQILMRDYTIEEFPIILLEHTEEVCYRLRQQNKLAQTVQFSIGYSKSYSGGFSKTHT
LSRPTNLTMDIYQVCLYFLNQQYTGEPIRSITISLTKLIGEGEEQISLFDNIIQREKEIKLTKVMDEIRTKFGKNSILRG
ISYTNNATARYRNTLLGGHKA

Specific function: Involved In Uv Protection And Mutation. Essential For Induced (Or Sos) Mutagenesis. May Modify The DNA Replication Machinery To Allow Bypass Synthesis Across A Damaged Template. [C]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=401, Percent_Identity=23.6907730673317, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786425, Length=272, Percent_Identity=25.3676470588235, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 48271; Mature: 48271

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDYSILPNRIILCVDLRSFYASVSCIKMGLDPLHTKLAVVGDMNRNGSIVLAATPPLKA
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCHHHHEEEEEECCCCCCCEEEEECCCHHH
MGVKKLARLYEIPRQKDILIVNPIMGTYIKCSNYITKLALQYVPIEDFHQYSIDEFFMDI
HHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TDSIHLFARNPNEFALQFKREIYEHTRIECTIGIAPNLLMSKVALDIEAKKNKDGVAYWT
CCCEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHEEEEECCCCCCEEEEE
YEDIPTKLWSIRPLSKFWGISHKTETKLNQKGIHSIGDLANYPLKYLKQSFGVIGEELHL
ECCCCCHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEE
HSNGIDFSRISEKYVPVTTSIGKSQILMRDYTIEEFPIILLEHTEEVCYRLRQQNKLAQT
ECCCCCHHHHCCCCCCEEECCCCCEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHH
VQFSIGYSKSYSGGFSKTHTLSRPTNLTMDIYQVCLYFLNQQYTGEPIRSITISLTKLIG
HEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
EGEEQISLFDNIIQREKEIKLTKVMDEIRTKFGKNSILRGISYTNNATARYRNTLLGGHK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHCCCCC
A
C
>Mature Secondary Structure
MYDYSILPNRIILCVDLRSFYASVSCIKMGLDPLHTKLAVVGDMNRNGSIVLAATPPLKA
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCHHHHEEEEEECCCCCCCEEEEECCCHHH
MGVKKLARLYEIPRQKDILIVNPIMGTYIKCSNYITKLALQYVPIEDFHQYSIDEFFMDI
HHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TDSIHLFARNPNEFALQFKREIYEHTRIECTIGIAPNLLMSKVALDIEAKKNKDGVAYWT
CCCEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHEEEEECCCCCCEEEEE
YEDIPTKLWSIRPLSKFWGISHKTETKLNQKGIHSIGDLANYPLKYLKQSFGVIGEELHL
ECCCCCHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEE
HSNGIDFSRISEKYVPVTTSIGKSQILMRDYTIEEFPIILLEHTEEVCYRLRQQNKLAQT
ECCCCCHHHHCCCCCCEEECCCCCEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHH
VQFSIGYSKSYSGGFSKTHTLSRPTNLTMDIYQVCLYFLNQQYTGEPIRSITISLTKLIG
HEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
EGEEQISLFDNIIQREKEIKLTKVMDEIRTKFGKNSILRGISYTNNATARYRNTLLGGHK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9722542; 9384377 [H]