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The map label for this gene is ntdA [H]

Identifier: 49186053

GI number: 49186053

Start: 3019744

End: 3020619

Strand: Reverse

Name: ntdA [H]

Synonym: BAS3048

Alternate gene names: 49186053

Gene position: 3020619-3019744 (Counterclockwise)

Preceding gene: 49186056

Following gene: 49186052

Centisome position: 57.77

GC content: 30.71

Gene sequence:

>876_bases
GTGAAAACTCTTACTACAATTTCTGGACATAGTAAAGACAATTTAGCTTTATTAAAGTGCCTACAGGGGGAAACAAAAGA
AAAAGAATTTGAAATTAGTAATATATTACCGAATCACAAGATGAAAGAGAAATTATTTAGGGAAAACAAATTGAAAATAG
ATATTGATATAGAAAAAGATATTTTCAATTATAGCAGAAAAAATATACAGAAAATAGAATTTATGCCAGTTAATCGGTTG
ATTTCTCAAGATGAGGTTGAAAAAATTATTGGAGCTTTAAAAGATGTTTTACCGACAGGTCAATTTACAAGTGGACCATT
TTCAAAAAAGCTAGAAGAAGTAATCGGAAGTTATTTAAATAAAAATTTTGTAATTGCAACAAGCAGTGGTACAGATGCCC
TTATGGTGTCATTGTTATCTATTGGTATTCAGCCGGGAGATGAAGTAATTATGCCAGCTAATAGTTTTGCTGCTACTGAA
AATGCTGTGTTAGCGGTCGGAGCAAAACCTATATTTGTAGATATAGATCAGAAGAGTTATTGTATTGATCCATCTAAAAT
AGAGGAAGCTATCACCCCAAAAACGAAATGCATTTTACCTGTACATTTGTATGGTAAGCAGTGTGAAATGAAAAAAATTC
GTGAAATCGCGGATATATATCAATTAAGAGTTATTGAAGATGCATGTCAAGCTATTGGTTCTTCAAATCTTGGAGAATAT
GGAGATATTATTGTCCTTAGTTTTAATCCATATAAGAATTTTGGTGTATGTGGCAAGGCAGGTGCAATAGTTACTAATAA
TGAAAATCTTGCAATACGTTGCAATCAATATAGTTATCATGGATTTGAAATTGATAAAAAAATAAAAAGGTATTAG

Upstream 100 bases:

>100_bases
ATAGAAAAACCCTCCGTAAAAAATATGTTGACATGTAATCGATAACATAAAATATAGTCTACTCATGATTTTCAAAATAA
TTTCTTAGAGGTGATTTAAC

Downstream 100 bases:

>100_bases
ACTTTGGATTCAATTCTAAAATTGATAATTTGCAAGCAGCTATTGGTTTGGAAAGAATTAAGTATTTATCATACAACAAT
TTAAAAAGAGCGTATTTAGC

Product: DegT/DnrJ/EryC1/StrS aminotransferase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKTLTTISGHSKDNLALLKCLQGETKEKEFEISNILPNHKMKEKLFRENKLKIDIDIEKDIFNYSRKNIQKIEFMPVNRL
ISQDEVEKIIGALKDVLPTGQFTSGPFSKKLEEVIGSYLNKNFVIATSSGTDALMVSLLSIGIQPGDEVIMPANSFAATE
NAVLAVGAKPIFVDIDQKSYCIDPSKIEEAITPKTKCILPVHLYGKQCEMKKIREIADIYQLRVIEDACQAIGSSNLGEY
GDIIVLSFNPYKNFGVCGKAGAIVTNNENLAIRCNQYSYHGFEIDKKIKRY

Sequences:

>Translated_291_residues
MKTLTTISGHSKDNLALLKCLQGETKEKEFEISNILPNHKMKEKLFRENKLKIDIDIEKDIFNYSRKNIQKIEFMPVNRL
ISQDEVEKIIGALKDVLPTGQFTSGPFSKKLEEVIGSYLNKNFVIATSSGTDALMVSLLSIGIQPGDEVIMPANSFAATE
NAVLAVGAKPIFVDIDQKSYCIDPSKIEEAITPKTKCILPVHLYGKQCEMKKIREIADIYQLRVIEDACQAIGSSNLGEY
GDIIVLSFNPYKNFGVCGKAGAIVTNNENLAIRCNQYSYHGFEIDKKIKRY
>Mature_291_residues
MKTLTTISGHSKDNLALLKCLQGETKEKEFEISNILPNHKMKEKLFRENKLKIDIDIEKDIFNYSRKNIQKIEFMPVNRL
ISQDEVEKIIGALKDVLPTGQFTSGPFSKKLEEVIGSYLNKNFVIATSSGTDALMVSLLSIGIQPGDEVIMPANSFAATE
NAVLAVGAKPIFVDIDQKSYCIDPSKIEEAITPKTKCILPVHLYGKQCEMKKIREIADIYQLRVIEDACQAIGSSNLGEY
GDIIVLSFNPYKNFGVCGKAGAIVTNNENLAIRCNQYSYHGFEIDKKIKRY

Specific function: Part of the ntdABC operon that biosynthesizes the NTD (3,3'-neotrehalosadiamine) antibiotic [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=217, Percent_Identity=37.7880184331797, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI2367285, Length=198, Percent_Identity=36.3636363636364, Blast_Score=120, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 32551; Mature: 32551

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLTTISGHSKDNLALLKCLQGETKEKEFEISNILPNHKMKEKLFRENKLKIDIDIEKD
CCCEEECCCCCCCCHHHHHHHCCCCCCCCEEHHHCCCCCHHHHHHHHCCCEEEEEEECHH
IFNYSRKNIQKIEFMPVNRLISQDEVEKIIGALKDVLPTGQFTSGPFSKKLEEVIGSYLN
HHHHHHHCCEEEEEECHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
KNFVIATSSGTDALMVSLLSIGIQPGDEVIMPANSFAATENAVLAVGAKPIFVDIDQKSY
CCEEEEECCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCEEEECCCEEEEEECCCCE
CIDPSKIEEAITPKTKCILPVHLYGKQCEMKKIREIADIYQLRVIEDACQAIGSSNLGEY
ECCHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GDIIVLSFNPYKNFGVCGKAGAIVTNNENLAIRCNQYSYHGFEIDKKIKRY
CCEEEEEECCCCCCCCCCCCCEEEECCCCEEEEECCCEECCEEHHHHHHCC
>Mature Secondary Structure
MKTLTTISGHSKDNLALLKCLQGETKEKEFEISNILPNHKMKEKLFRENKLKIDIDIEKD
CCCEEECCCCCCCCHHHHHHHCCCCCCCCEEHHHCCCCCHHHHHHHHCCCEEEEEEECHH
IFNYSRKNIQKIEFMPVNRLISQDEVEKIIGALKDVLPTGQFTSGPFSKKLEEVIGSYLN
HHHHHHHCCEEEEEECHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
KNFVIATSSGTDALMVSLLSIGIQPGDEVIMPANSFAATENAVLAVGAKPIFVDIDQKSY
CCEEEEECCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCEEEECCCEEEEEECCCCE
CIDPSKIEEAITPKTKCILPVHLYGKQCEMKKIREIADIYQLRVIEDACQAIGSSNLGEY
ECCHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GDIIVLSFNPYKNFGVCGKAGAIVTNNENLAIRCNQYSYHGFEIDKKIKRY
CCEEEEEECCCCCCCCCCCCCEEEECCCCEEEEECCCEECCEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]