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The map label for this gene is glnK [H]

Identifier: 49185936

GI number: 49185936

Start: 2899706

End: 2900308

Strand: Reverse

Name: glnK [H]

Synonym: BAS2930

Alternate gene names: 49185936

Gene position: 2900308-2899706 (Counterclockwise)

Preceding gene: 49185937

Following gene: 49185935

Centisome position: 55.47

GC content: 33.83

Gene sequence:

>603_bases
ATGGATTTTCAGTTTGGGGATTTAAGGCAACAGGCATTACAAATTGCTGGTGAGGTTCATGACGTTAAAAAGGATAACCA
ACGTATTTTTGCAGGACTTTCAAAATTAATTTCTGATGAAAGTTTTACAGATTATATGTCTGTACATGAACTAGTAAATA
TCATTATACGGGCAAATGCGAAATATGCACGGTTGCTAGAGAAAGACATCCAATTTGTGTATAAAATTGATGGTGTGCAT
CCTCATTATCATATTTACACAATCTTATCTATTATAAATAATATCGTTACAAACGCTGTAGAGGCTATCCAAGGTATGGG
AACCATCACAATTGACATTAATAAAGACCACCATTTTGTTGAATTTCAAATAGGCGATAATGGTCCCGGTATTTCTTCAA
AATATAAAGATTCAATTTTTGAGCCTGGGTTTACTTCTAAATATGATGATTTAGGCAATCCATCGACAGGTATCGGATTA
TCGTATGTTAAAGAAATGGTCGAACAACTTGAAGGTGATGTTACGCTTGAGGACAGAACCGAAGGAAAAGGATCAATTTT
TATAATTAGATTAGGGATTGATCATATAATTTCGAAAGGGTGA

Upstream 100 bases:

>100_bases
AAGATGCTGTTCATTTAAAAAAACATTACAAGATGCTGAGAATATAACAAAAAAATCCTATGATTTATATAAAACTTTAG
ACTCTTTTGAGCACAAACAG

Downstream 100 bases:

>100_bases
TTCTATGTATTTTTATATAGTAGATGATGAAAAAGCGGTTCGCTCAATGTTGGCTCAAATTATCGAGGATGAAGATCTTG
GGGAGGTTATAGGAGAAGCT

Product: two-component sensor histidine kinase, C-terminus

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MDFQFGDLRQQALQIAGEVHDVKKDNQRIFAGLSKLISDESFTDYMSVHELVNIIIRANAKYARLLEKDIQFVYKIDGVH
PHYHIYTILSIINNIVTNAVEAIQGMGTITIDINKDHHFVEFQIGDNGPGISSKYKDSIFEPGFTSKYDDLGNPSTGIGL
SYVKEMVEQLEGDVTLEDRTEGKGSIFIIRLGIDHIISKG

Sequences:

>Translated_200_residues
MDFQFGDLRQQALQIAGEVHDVKKDNQRIFAGLSKLISDESFTDYMSVHELVNIIIRANAKYARLLEKDIQFVYKIDGVH
PHYHIYTILSIINNIVTNAVEAIQGMGTITIDINKDHHFVEFQIGDNGPGISSKYKDSIFEPGFTSKYDDLGNPSTGIGL
SYVKEMVEQLEGDVTLEDRTEGKGSIFIIRLGIDHIISKG
>Mature_200_residues
MDFQFGDLRQQALQIAGEVHDVKKDNQRIFAGLSKLISDESFTDYMSVHELVNIIIRANAKYARLLEKDIQFVYKIDGVH
PHYHIYTILSIINNIVTNAVEAIQGMGTITIDINKDHHFVEFQIGDNGPGISSKYKDSIFEPGFTSKYDDLGNPSTGIGL
SYVKEMVEQLEGDVTLEDRTEGKGSIFIIRLGIDHIISKG

Specific function: Member of the two-component regulatory system glnK/glnL that positively regulates the expression of the glsA-glnT operon in response to glutamine. Probably activates glnL by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=129, Percent_Identity=29.4573643410853, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 22449; Mature: 22449

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFQFGDLRQQALQIAGEVHDVKKDNQRIFAGLSKLISDESFTDYMSVHELVNIIIRANA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
KYARLLEKDIQFVYKIDGVHPHYHIYTILSIINNIVTNAVEAIQGMGTITIDINKDHHFV
HHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEE
EFQIGDNGPGISSKYKDSIFEPGFTSKYDDLGNPSTGIGLSYVKEMVEQLEGDVTLEDRT
EEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCC
EGKGSIFIIRLGIDHIISKG
CCCCCEEEEEECHHHHHCCC
>Mature Secondary Structure
MDFQFGDLRQQALQIAGEVHDVKKDNQRIFAGLSKLISDESFTDYMSVHELVNIIIRANA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
KYARLLEKDIQFVYKIDGVHPHYHIYTILSIINNIVTNAVEAIQGMGTITIDINKDHHFV
HHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEE
EFQIGDNGPGISSKYKDSIFEPGFTSKYDDLGNPSTGIGLSYVKEMVEQLEGDVTLEDRT
EEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCC
EGKGSIFIIRLGIDHIISKG
CCCCCEEEEEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 8011666 [H]