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The map label for this gene is katE [H]

Identifier: 49185822

GI number: 49185822

Start: 2794923

End: 2796302

Strand: Direct

Name: katE [H]

Synonym: BAS2816

Alternate gene names: 49185822

Gene position: 2794923-2796302 (Clockwise)

Preceding gene: 49185814

Following gene: 49185834

Centisome position: 53.45

GC content: 37.75

Gene sequence:

>1380_bases
ATGGGTGAAAACCATGATAAACAGAGGCAATCTTTACTAGGGAAAGACTTTAATGAAAATGGAGAACGTAATGAACAAGC
AATCCTTCACTCTCAAACAGTTGGTTCACGTGGACCTGTTTTAGAGCAAGATAGTGTGCTTCACGAGGCGTTACAAGAAT
TTATTCACGAAAAAATTTTAGAAAGACCTGTTCATGTAAAAGGATTCGGTGCGTTCGGTTATTTTCAAACGATCTATCCA
ATGTCCGAACATACTAAACTAAGTTTTCTACAACATTCTAATGAGAAAGTTCCTGTTATGGTTCGATTTTCATTAGCTGT
TAGTACGAAAGGAACACCTGACACTGCTAGAAATGTACGTGGTTTTTCTACAAAATTCTATACAAAAGAAGGTATTTTCG
ATCTATTATGTAATCACATTCCTGTCTTTTCTGTTCGCGATCCGATGCGTTTCCCTGAAACCATTCAAGCGTTGTCACCT
TCACCTAAAAATAACTTACTAGACCCGAATAGATTTTGGAGTTTTGTCGCTAGAGCACCTGAATCCATTCATTTTGTTGT
CCATTTGTACTCTGATAATGGTACGGCCAAAAGCTTTCGCCGCATTCCAGGACATAGTGTAAATACATATGTTTGGAGAA
ATGCAGAAGGTAACCGCAAATATGTAAAGTATCATTGGTACCCATTTGAAGGTGTACAATCCATTACTAATGAGGAAGCG
AATAAACTAGCTGCCGAAAACCCTGATTATAGCGGGAAAGATTTATATGACGCAATTGCAAATGGTAAACCAGTGGAATA
TGGTTTATACGTCCAGCTTATGGATCCGAAAGATGAAGCGCATCTTTCTTACGATCCTTTAGATGATACAAAAGCATGGG
ATGAAAAAGCGTATCCTCTTATACCAGTCGGCAAAATGGTATTAAATAAAAACCCTGAAAATTATATGGAACAAGTAGAA
AAAGTCGCTTTCTCCCCTTCTAATTTACTGAACGGCGCAGAATTATCAGATGATAAAATGTTGCAAGGACGTGCAAACAT
TTATAGTGATTCTCAAAGAAGAAGAATTGGTCCTGAATTTCGTAAATTAGCAATTAACCAACAGCAAGATTGGACACCTG
CTAATCAAATAACGAGCGGTGACGGAAGGTACGTTGAAGGTAAACTTGAGAGAACTTCTATACCGAAACAAGATGACTTT
ACACAGGCTGGTGAATTTTATGCGAAGTTACAACCGATAGAAAAAGAACATCTTGCTGAAAACTTAGCTAGTGACTTGAA
AGTTATATCCGATGATATTAGAAAGGTCGTTTTGGGGTATTTTCATAACGTGTCAGCTGATTTGGTGAAGAGGATTGAAA
GTGCGATGCAACAGCTTTGA

Upstream 100 bases:

>100_bases
AGCGGTCTGTTACTATTTTGAGCTTTGCGTGTTATACATAATCAAGGCTAAAAAATCATATTTAGTAACAATGAACAAAA
AAGATTTGGAGGCTATATTG

Downstream 100 bases:

>100_bases
GAATATAAAAAACGTCATTTTCAATCTTTAAAATGACGTTTTTTATGGCGAAATTACTAGGGATTTCTATCGCTTTATTT
ACAATGATTAACGAAATTTT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MGENHDKQRQSLLGKDFNENGERNEQAILHSQTVGSRGPVLEQDSVLHEALQEFIHEKILERPVHVKGFGAFGYFQTIYP
MSEHTKLSFLQHSNEKVPVMVRFSLAVSTKGTPDTARNVRGFSTKFYTKEGIFDLLCNHIPVFSVRDPMRFPETIQALSP
SPKNNLLDPNRFWSFVARAPESIHFVVHLYSDNGTAKSFRRIPGHSVNTYVWRNAEGNRKYVKYHWYPFEGVQSITNEEA
NKLAAENPDYSGKDLYDAIANGKPVEYGLYVQLMDPKDEAHLSYDPLDDTKAWDEKAYPLIPVGKMVLNKNPENYMEQVE
KVAFSPSNLLNGAELSDDKMLQGRANIYSDSQRRRIGPEFRKLAINQQQDWTPANQITSGDGRYVEGKLERTSIPKQDDF
TQAGEFYAKLQPIEKEHLAENLASDLKVISDDIRKVVLGYFHNVSADLVKRIESAMQQL

Sequences:

>Translated_459_residues
MGENHDKQRQSLLGKDFNENGERNEQAILHSQTVGSRGPVLEQDSVLHEALQEFIHEKILERPVHVKGFGAFGYFQTIYP
MSEHTKLSFLQHSNEKVPVMVRFSLAVSTKGTPDTARNVRGFSTKFYTKEGIFDLLCNHIPVFSVRDPMRFPETIQALSP
SPKNNLLDPNRFWSFVARAPESIHFVVHLYSDNGTAKSFRRIPGHSVNTYVWRNAEGNRKYVKYHWYPFEGVQSITNEEA
NKLAAENPDYSGKDLYDAIANGKPVEYGLYVQLMDPKDEAHLSYDPLDDTKAWDEKAYPLIPVGKMVLNKNPENYMEQVE
KVAFSPSNLLNGAELSDDKMLQGRANIYSDSQRRRIGPEFRKLAINQQQDWTPANQITSGDGRYVEGKLERTSIPKQDDF
TQAGEFYAKLQPIEKEHLAENLASDLKVISDDIRKVVLGYFHNVSADLVKRIESAMQQL
>Mature_458_residues
GENHDKQRQSLLGKDFNENGERNEQAILHSQTVGSRGPVLEQDSVLHEALQEFIHEKILERPVHVKGFGAFGYFQTIYPM
SEHTKLSFLQHSNEKVPVMVRFSLAVSTKGTPDTARNVRGFSTKFYTKEGIFDLLCNHIPVFSVRDPMRFPETIQALSPS
PKNNLLDPNRFWSFVARAPESIHFVVHLYSDNGTAKSFRRIPGHSVNTYVWRNAEGNRKYVKYHWYPFEGVQSITNEEAN
KLAAENPDYSGKDLYDAIANGKPVEYGLYVQLMDPKDEAHLSYDPLDDTKAWDEKAYPLIPVGKMVLNKNPENYMEQVEK
VAFSPSNLLNGAELSDDKMLQGRANIYSDSQRRRIGPEFRKLAINQQQDWTPANQITSGDGRYVEGKLERTSIPKQDDFT
QAGEFYAKLQPIEKEHLAENLASDLKVISDDIRKVVLGYFHNVSADLVKRIESAMQQL

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Involved in sporulation [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=461, Percent_Identity=36.6594360086768, Blast_Score=310, Evalue=2e-84,
Organism=Escherichia coli, GI48994891, Length=343, Percent_Identity=40.8163265306122, Blast_Score=276, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI71998444, Length=456, Percent_Identity=35.5263157894737, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI25147792, Length=456, Percent_Identity=35.5263157894737, Blast_Score=294, Evalue=7e-80,
Organism=Caenorhabditis elegans, GI25151141, Length=456, Percent_Identity=35.5263157894737, Blast_Score=294, Evalue=7e-80,
Organism=Saccharomyces cerevisiae, GI6320462, Length=339, Percent_Identity=40.117994100295, Blast_Score=266, Evalue=7e-72,
Organism=Saccharomyces cerevisiae, GI6321525, Length=373, Percent_Identity=34.0482573726542, Blast_Score=226, Evalue=4e-60,
Organism=Drosophila melanogaster, GI17981717, Length=460, Percent_Identity=36.304347826087, Blast_Score=306, Evalue=2e-83,
Organism=Drosophila melanogaster, GI19920968, Length=335, Percent_Identity=40, Blast_Score=290, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614
- InterPro:   IPR002818 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel; PF01965 DJ-1_PfpI [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 52373; Mature: 52242

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGENHDKQRQSLLGKDFNENGERNEQAILHSQTVGSRGPVLEQDSVLHEALQEFIHEKIL
CCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ERPVHVKGFGAFGYFQTIYPMSEHTKLSFLQHSNEKVPVMVRFSLAVSTKGTPDTARNVR
HCCCCEEEECCHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEEEEEEEECCCCCHHHHCCC
GFSTKFYTKEGIFDLLCNHIPVFSVRDPMRFPETIQALSPSPKNNLLDPNRFWSFVARAP
CCCEEHCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
ESIHFVVHLYSDNGTAKSFRRIPGHSVNTYVWRNAEGNRKYVKYHWYPFEGVQSITNEEA
CCEEEEEEEECCCCCHHHHHHCCCCCCCEEEEECCCCCCEEEEEEECCHHHHHHHHHHHH
NKLAAENPDYSGKDLYDAIANGKPVEYGLYVQLMDPKDEAHLSYDPLDDTKAWDEKAYPL
HHHHCCCCCCCCHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
IPVGKMVLNKNPENYMEQVEKVAFSPSNLLNGAELSDDKMLQGRANIYSDSQRRRIGPEF
CCCCHHHHCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHCCHHHCCCCHHHHCCHHH
RKLAINQQQDWTPANQITSGDGRYVEGKLERTSIPKQDDFTQAGEFYAKLQPIEKEHLAE
HHHHCCCCCCCCCHHCCCCCCCCEEECEEHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHH
NLASDLKVISDDIRKVVLGYFHNVSADLVKRIESAMQQL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
GENHDKQRQSLLGKDFNENGERNEQAILHSQTVGSRGPVLEQDSVLHEALQEFIHEKIL
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ERPVHVKGFGAFGYFQTIYPMSEHTKLSFLQHSNEKVPVMVRFSLAVSTKGTPDTARNVR
HCCCCEEEECCHHHHHHHCCCCCCCCHHHHHCCCCCCEEEEEEEEEEECCCCCHHHHCCC
GFSTKFYTKEGIFDLLCNHIPVFSVRDPMRFPETIQALSPSPKNNLLDPNRFWSFVARAP
CCCEEHCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
ESIHFVVHLYSDNGTAKSFRRIPGHSVNTYVWRNAEGNRKYVKYHWYPFEGVQSITNEEA
CCEEEEEEEECCCCCHHHHHHCCCCCCCEEEEECCCCCCEEEEEEECCHHHHHHHHHHHH
NKLAAENPDYSGKDLYDAIANGKPVEYGLYVQLMDPKDEAHLSYDPLDDTKAWDEKAYPL
HHHHCCCCCCCCHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
IPVGKMVLNKNPENYMEQVEKVAFSPSNLLNGAELSDDKMLQGRANIYSDSQRRRIGPEF
CCCCHHHHCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHCCHHHCCCCHHHHCCHHH
RKLAINQQQDWTPANQITSGDGRYVEGKLERTSIPKQDDFTQAGEFYAKLQPIEKEHLAE
HHHHCCCCCCCCCHHCCCCCCCCEEECEEHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHH
NLASDLKVISDDIRKVVLGYFHNVSADLVKRIESAMQQL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]