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The map label for this gene is des [H]

Identifier: 49185794

GI number: 49185794

Start: 2768803

End: 2769762

Strand: Reverse

Name: des [H]

Synonym: BAS2788

Alternate gene names: 49185794

Gene position: 2769762-2768803 (Counterclockwise)

Preceding gene: 49185795

Following gene: 49185793

Centisome position: 52.97

GC content: 36.35

Gene sequence:

>960_bases
GTGTGGCAACTTATTAACACAGTCGTGCCGTTTATTATTTTATGGTACCTTGCTTATAAAAGTTTGTCCGTTTCTTATCT
GTTAGCAGTAGTTCCATCTCTGTTAGCTGCTGGTTTTATGACACGAATTTTCATTATTTTTCATGATTGTACCCATTATT
CATTCTTTAAAAGTCGACGTGCAAATAGAATAGTAGGGACATGTATGGGTGTGTTAACGTTATTCCCATTTGATCAATGG
GGGCATGATCATGCGATTCATCACGCTACAAGTGGTAATTTAGATAAGAGAGGTACAGGAGATATTTGGACGCTTACAGT
GGATGAATATGTAGCTGCGCCACTTAGACTTCGTTTAGCATATCGTTTATATCGCAATCCATTCGTTATGTTTGGGTTAG
GTCCGATTTATGTATTCTTGCTTAAAAATAGATTTAACCGAAAAGGTGCAAGACAGAAAGAACGTATGAATACGTATTTG
ACGAATATTATAATTGTTGCCGTAGTAGCTATACTTTGCTGGGCAATAGGATGGCAATCGTTCCTATTAGTACATGGTAC
GATATTCTTAATTGCAGGTTCAGTAGGGATTTGGCTGTTTTACGTACAGCACACATTCGAGGATTCTTATTTTGAAGAAG
ATAAAGATTGGGAATATGTGAAAGCGGCCGTAGAGGGAAGTTCATTTTATAAACTTCCAAAAATCTTGCAATTCCTAACT
GGTAATATTGGATTCCATCATGTTCACCATTTAAGCCCAAGAGTACCAAACTATAAACTAGAAGAGGCACACAATAATAC
GCTTCCGTTAAAAAATGTACCAACGATTACACTTGCTACAAGCTTGCGTTCACTTCGTTTCCGTCTTTGGGATGAGAAAA
GTAACAATTTTGTTAGCTTTAAAGAAGTCAAAAATATAATTAAAAATAATGTTTCTGTCCGGGTGAAATCGGAACTATAA

Upstream 100 bases:

>100_bases
AGCAACATAAAGGAAGGGAATTAGAAAAAATGACATTAGAAAAAACTAAAAATTTAAAAAACAAGTTGCCCCTTATGAAA
AATCAACAATTAAAAAAAGT

Downstream 100 bases:

>100_bases
ATTCATCGGCTATAAAACTCCCCTTAATCATTATCGATGTAAGGGGAGTTTTTGTTATGTATAACTGATATCGGGGACGT
GGAAAAATACATGTGTAGAT

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MWQLINTVVPFIILWYLAYKSLSVSYLLAVVPSLLAAGFMTRIFIIFHDCTHYSFFKSRRANRIVGTCMGVLTLFPFDQW
GHDHAIHHATSGNLDKRGTGDIWTLTVDEYVAAPLRLRLAYRLYRNPFVMFGLGPIYVFLLKNRFNRKGARQKERMNTYL
TNIIIVAVVAILCWAIGWQSFLLVHGTIFLIAGSVGIWLFYVQHTFEDSYFEEDKDWEYVKAAVEGSSFYKLPKILQFLT
GNIGFHHVHHLSPRVPNYKLEEAHNNTLPLKNVPTITLATSLRSLRFRLWDEKSNNFVSFKEVKNIIKNNVSVRVKSEL

Sequences:

>Translated_319_residues
MWQLINTVVPFIILWYLAYKSLSVSYLLAVVPSLLAAGFMTRIFIIFHDCTHYSFFKSRRANRIVGTCMGVLTLFPFDQW
GHDHAIHHATSGNLDKRGTGDIWTLTVDEYVAAPLRLRLAYRLYRNPFVMFGLGPIYVFLLKNRFNRKGARQKERMNTYL
TNIIIVAVVAILCWAIGWQSFLLVHGTIFLIAGSVGIWLFYVQHTFEDSYFEEDKDWEYVKAAVEGSSFYKLPKILQFLT
GNIGFHHVHHLSPRVPNYKLEEAHNNTLPLKNVPTITLATSLRSLRFRLWDEKSNNFVSFKEVKNIIKNNVSVRVKSEL
>Mature_319_residues
MWQLINTVVPFIILWYLAYKSLSVSYLLAVVPSLLAAGFMTRIFIIFHDCTHYSFFKSRRANRIVGTCMGVLTLFPFDQW
GHDHAIHHATSGNLDKRGTGDIWTLTVDEYVAAPLRLRLAYRLYRNPFVMFGLGPIYVFLLKNRFNRKGARQKERMNTYL
TNIIIVAVVAILCWAIGWQSFLLVHGTIFLIAGSVGIWLFYVQHTFEDSYFEEDKDWEYVKAAVEGSSFYKLPKILQFLT
GNIGFHHVHHLSPRVPNYKLEEAHNNTLPLKNVPTITLATSLRSLRFRLWDEKSNNFVSFKEVKNIIKNNVSVRVKSEL

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 36955; Mature: 36955

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50999 COX2_TM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCEEEEECCC
>Mature Secondary Structure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HHHHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]