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The map label for this gene is lsrK [H]

Identifier: 49185775

GI number: 49185775

Start: 2750292

End: 2750534

Strand: Direct

Name: lsrK [H]

Synonym: BAS2769

Alternate gene names: 49185775

Gene position: 2750292-2750534 (Clockwise)

Preceding gene: 49185774

Following gene: 49185776

Centisome position: 52.6

GC content: 44.44

Gene sequence:

>243_bases
GTGAAAGAAGCAGCTGCTTTAGGAACTGCGATTGCTGCAGGAGTTGGTGCTGGCATATATTCATCTATGGAAGAGACTGC
CGAACAGTTTGTACAGTGGGAGCAAACATTCGAACCAGTTACTGAAAATCACGAACTATATAAAGAGTTCTATGAAACAT
GGAAAACTGTGTATAACAGTCAGCTCGCTTTAGCTGATAACGGGCTCACCTCACACATGTGGATTGCGCCTGGTGCACTG
TAA

Upstream 100 bases:

>100_bases
ATTCCCTTCTGAAGTTATTTTTGCTGGTGGTGCCGCTAAAGGAAAACTATGGCCACAAATTCTATCAGACGTCCTTGGTA
TTCCTGTAAAAGTACCTGTT

Downstream 100 bases:

>100_bases
CACATTACATAAAGGAGTGGAATGTATGTTAAAAGCGAATGAAAATGACTTCTCCTATCGCTTCGGTGATAACGGGCCGA
AATATTTAATACAAGGTCCG

Product: sugar (pentulose and hexulose) kinase, C-terminus

Products: NA

Alternate protein names: AI-2 kinase [H]

Number of amino acids: Translated: 80; Mature: 80

Protein sequence:

>80_residues
MKEAAALGTAIAAGVGAGIYSSMEETAEQFVQWEQTFEPVTENHELYKEFYETWKTVYNSQLALADNGLTSHMWIAPGAL

Sequences:

>Translated_80_residues
MKEAAALGTAIAAGVGAGIYSSMEETAEQFVQWEQTFEPVTENHELYKEFYETWKTVYNSQLALADNGLTSHMWIAPGAL
>Mature_80_residues
MKEAAALGTAIAAGVGAGIYSSMEETAEQFVQWEQTFEPVTENHELYKEFYETWKTVYNSQLALADNGLTSHMWIAPGAL

Specific function: Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787789, Length=78, Percent_Identity=58.974358974359, Blast_Score=102, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018484 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: NA

Molecular weight: Translated: 8845; Mature: 8845

Theoretical pI: Translated: 4.04; Mature: 4.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEAAALGTAIAAGVGAGIYSSMEETAEQFVQWEQTFEPVTENHELYKEFYETWKTVYNS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
QLALADNGLTSHMWIAPGAL
CHHCCCCCCCCCEECCCCCC
>Mature Secondary Structure
MKEAAALGTAIAAGVGAGIYSSMEETAEQFVQWEQTFEPVTENHELYKEFYETWKTVYNS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
QLALADNGLTSHMWIAPGAL
CHHCCCCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA