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The map label for this gene is rpiA

Identifier: 49185609

GI number: 49185609

Start: 2594042

End: 2594704

Strand: Direct

Name: rpiA

Synonym: BAS2602

Alternate gene names: 49185609

Gene position: 2594042-2594704 (Clockwise)

Preceding gene: 49185608

Following gene: 49185610

Centisome position: 49.61

GC content: 35.6

Gene sequence:

>663_bases
ATGGATTTAAAACAGATAGCTGGTGAATATGCTGCAACCTTCGTAAAAGATGGTATGAAGATTGGTCTTGGTACAGGATC
AACCGCATACTGGACGATACAAAAATTAGGTCAACGTGTAAAAGAGGGATTATCAATTCAAGCTGTCCCGACATCAAAGG
AAACGGAAGCATTGGCACAGCAGCTAAATATTCCGTTGATTTCGTTAAACGACGTACAAAGTCTTGATCTTACAATTGAT
GGAGCTGATGAAATTGATTCTAATTTACAGCTTATTAAAGGAGGTGGTGGTGCATTACTTCGCGAGAAAATTGTAGCCTC
CTCCTCGAAAGAACTTATCATTATCGTTGATGAATCAAAAGTTGTGACGCGTTTAGGGACTTTTCCATTACCTATTGAAA
TCATACCTTTTGCATGGAAACAAACCGAAAGTAAAATTCAATCTTTAGGATGTCAAACAACGTTACGCTTAAAAAATAAT
GAAACGTTTATCACCGATAATAATAACATGATTATCGATTGTATATTCCCTAATCATATACCTACTCCTTCCGATTTACA
CAAAAGATTAAAAATGATTACTGGTGTAGTTGAAACCGGATTGTTTGTTAATATGACTAGTAAGGCGATTATTGGAACAA
AAAACGGGATACAGGAATTATAA

Upstream 100 bases:

>100_bases
TCTTGTCAAATGCGTGTACATAAGGATATAGTAGTTCGCCCAGTACTTACAGTTGAAAGTTCAGGTCTTGATGCTGGACC
ACGTCCGGCGGAGTAAAGCG

Downstream 100 bases:

>100_bases
TGAATGCTGACTCTTACAGTCAGCTTTTTTATATTTTCTCGTTATTACGTAACATTATGATATACTATGAAAACAAAAGC
ACATCACACTAGAAAGGATT

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MDLKQIAGEYAATFVKDGMKIGLGTGSTAYWTIQKLGQRVKEGLSIQAVPTSKETEALAQQLNIPLISLNDVQSLDLTID
GADEIDSNLQLIKGGGGALLREKIVASSSKELIIIVDESKVVTRLGTFPLPIEIIPFAWKQTESKIQSLGCQTTLRLKNN
ETFITDNNNMIIDCIFPNHIPTPSDLHKRLKMITGVVETGLFVNMTSKAIIGTKNGIQEL

Sequences:

>Translated_220_residues
MDLKQIAGEYAATFVKDGMKIGLGTGSTAYWTIQKLGQRVKEGLSIQAVPTSKETEALAQQLNIPLISLNDVQSLDLTID
GADEIDSNLQLIKGGGGALLREKIVASSSKELIIIVDESKVVTRLGTFPLPIEIIPFAWKQTESKIQSLGCQTTLRLKNN
ETFITDNNNMIIDCIFPNHIPTPSDLHKRLKMITGVVETGLFVNMTSKAIIGTKNGIQEL
>Mature_220_residues
MDLKQIAGEYAATFVKDGMKIGLGTGSTAYWTIQKLGQRVKEGLSIQAVPTSKETEALAQQLNIPLISLNDVQSLDLTID
GADEIDSNLQLIKGGGGALLREKIVASSSKELIIIVDESKVVTRLGTFPLPIEIIPFAWKQTESKIQSLGCQTTLRLKNN
ETFITDNNNMIIDCIFPNHIPTPSDLHKRLKMITGVVETGLFVNMTSKAIIGTKNGIQEL

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=223, Percent_Identity=38.1165919282511, Blast_Score=140, Evalue=9e-34,
Organism=Escherichia coli, GI1789280, Length=220, Percent_Identity=39.5454545454545, Blast_Score=141, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17551758, Length=222, Percent_Identity=32.8828828828829, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324669, Length=215, Percent_Identity=34.8837209302326, Blast_Score=123, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281364072, Length=206, Percent_Identity=38.3495145631068, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_BACAN (Q81PL1)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_845140.1
- RefSeq:   YP_019433.1
- RefSeq:   YP_028861.1
- ProteinModelPortal:   Q81PL1
- SMR:   Q81PL1
- EnsemblBacteria:   EBBACT00000009976
- EnsemblBacteria:   EBBACT00000015499
- EnsemblBacteria:   EBBACT00000022832
- GeneID:   1088394
- GeneID:   2816795
- GeneID:   2850128
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_2791
- KEGG:   bar:GBAA_2791
- KEGG:   bat:BAS2602
- TIGR:   BA_2791
- TIGR:   GBAA_2791
- GeneTree:   EBGT00050000003998
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- ProtClustDB:   PRK00702
- BioCyc:   BANT260799:BAS2602-MONOMER
- BioCyc:   BANT261594:GBAA2791-MONOMER
- BRENDA:   5.3.1.6
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23979; Mature: 23979

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKQIAGEYAATFVKDGMKIGLGTGSTAYWTIQKLGQRVKEGLSIQAVPTSKETEALAQ
CCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
QLNIPLISLNDVQSLDLTIDGADEIDSNLQLIKGGGGALLREKIVASSSKELIIIVDESK
HHCCCEEEECCCCEEEEEECCHHHCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCH
VVTRLGTFPLPIEIIPFAWKQTESKIQSLGCQTTLRLKNNETFITDNNNMIIDCIFPNHI
HHHHHCCCCCCEEEECCCHHHHHHHHHHCCCEEEEEEECCEEEEECCCCEEEEEECCCCC
PTPSDLHKRLKMITGVVETGLFVNMTSKAIIGTKNGIQEL
CCHHHHHHHHHHHHHHHHCCEEEEECCCEEEECCCCCCCC
>Mature Secondary Structure
MDLKQIAGEYAATFVKDGMKIGLGTGSTAYWTIQKLGQRVKEGLSIQAVPTSKETEALAQ
CCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
QLNIPLISLNDVQSLDLTIDGADEIDSNLQLIKGGGGALLREKIVASSSKELIIIVDESK
HHCCCEEEECCCCEEEEEECCHHHCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCH
VVTRLGTFPLPIEIIPFAWKQTESKIQSLGCQTTLRLKNNETFITDNNNMIIDCIFPNHI
HHHHHCCCCCCEEEECCCHHHHHHHHHHCCCEEEEEEECCEEEEECCCCEEEEEECCCCC
PTPSDLHKRLKMITGVVETGLFVNMTSKAIIGTKNGIQEL
CCHHHHHHHHHHHHHHHHCCEEEEECCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629