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The map label for this gene is yxdK [H]

Identifier: 49185429

GI number: 49185429

Start: 2418945

End: 2419703

Strand: Direct

Name: yxdK [H]

Synonym: BAS2421

Alternate gene names: 49185429

Gene position: 2418945-2419703 (Clockwise)

Preceding gene: 49185428

Following gene: 49185431

Centisome position: 46.26

GC content: 32.41

Gene sequence:

>759_bases
ATGAATCTGTTCAAAATTCTGATTTTGCAGCTATATCTGCTGCTCTTCAACACTTGCTTGAGGTACAATATCGCCATTAT
CAAAATCAGCTTCAAATACAAGAGTAAAAATAATGATCATTTAACTTTTATGAATCAGTGGATTCATCAAATGAAAACAC
CTTTATCTGTCATAGAATTAATTACACAAGATGAAGTTGATCCACGCTTCGAAAGTATAAATGAGGAAACAGATAGACTG
AAAAAGGGGTTAGAGATGGCATTGTATGTTGCACGTTTAGAAGCATTTACACAAGATTTTTATGTAGAAAAAGTACAGCT
ATATAAAATAGTGAATGATTCTGTGCACGAACATAAACGTTTCTTTATCCGGAATTTTGTATATCCAGAGCTTAAAGTTG
AGAAAGATATTACTGTAGAAAGTGATGCGAAATGGTTACAATTTTTAATTGGACAAATACTATCGAATGCGATTAAATAT
TCATCTGGTAGTAGAGAGAAGATTAAAGTGAAAGCTTGTAAGGAAGGTAATACAGCCATACTTGAAATTGCTGATAACGG
TGTAGGCATACCGAAGCAAGATTTACCAAGAGTATTTAAACCTTTCTTTACAGGAGAAAATGGCAGAGATTTTAAAGAAT
CAACTGGAATGGGGCTATATCTTGTATATGAAATTACGAAACAATTAGGACATAGTGTAGAAATCCATTCAGAAGTTGGT
AAAGGTACCGTTGTACGTATTAAATTTTTTAATGTGTAA

Upstream 100 bases:

>100_bases
ATGTTTTTAGGTGCCTTTTTTATGGTAGGTTATTTAATATTTCGTTACTTTACACATCGTTCTTTTTATGAGCGTTTAGC
AAACCCGATGCAATCTTTAG

Downstream 100 bases:

>100_bases
AAATAAGTAATCTAGGCTAAAGAACTTTGGAGATAAGTTTTTTAGCCTTTTTGTATAGCGGTTATATGAAATGGTAAAAC
GTCATATTAGTATGTATAAT

Product: sensor histidine kinase, C-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MNLFKILILQLYLLLFNTCLRYNIAIIKISFKYKSKNNDHLTFMNQWIHQMKTPLSVIELITQDEVDPRFESINEETDRL
KKGLEMALYVARLEAFTQDFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAIKY
SSGSREKIKVKACKEGNTAILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLGHSVEIHSEVG
KGTVVRIKFFNV

Sequences:

>Translated_252_residues
MNLFKILILQLYLLLFNTCLRYNIAIIKISFKYKSKNNDHLTFMNQWIHQMKTPLSVIELITQDEVDPRFESINEETDRL
KKGLEMALYVARLEAFTQDFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAIKY
SSGSREKIKVKACKEGNTAILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLGHSVEIHSEVG
KGTVVRIKFFNV
>Mature_252_residues
MNLFKILILQLYLLLFNTCLRYNIAIIKISFKYKSKNNDHLTFMNQWIHQMKTPLSVIELITQDEVDPRFESINEETDRL
KKGLEMALYVARLEAFTQDFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAIKY
SSGSREKIKVKACKEGNTAILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLGHSVEIHSEVG
KGTVVRIKFFNV

Specific function: Probable member of the two-component regulatory system yxdK/yxdJ. May activate yxdJ in response to the antibacterial protein LL-37 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=224, Percent_Identity=25.8928571428571, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 29327; Mature: 29327

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFKILILQLYLLLFNTCLRYNIAIIKISFKYKSKNNDHLTFMNQWIHQMKTPLSVIEL
CHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHH
ITQDEVDPRFESINEETDRLKKGLEMALYVARLEAFTQDFYVEKVQLYKIVNDSVHEHKR
HHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAIKYSSGSREKIKVKACKEGNTAI
HHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEE
LEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLGHSVEIHSEVG
EEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCEEHHHHHHHHHCCCEEEEHHCC
KGTVVRIKFFNV
CCEEEEEEEECC
>Mature Secondary Structure
MNLFKILILQLYLLLFNTCLRYNIAIIKISFKYKSKNNDHLTFMNQWIHQMKTPLSVIEL
CHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHH
ITQDEVDPRFESINEETDRLKKGLEMALYVARLEAFTQDFYVEKVQLYKIVNDSVHEHKR
HHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAIKYSSGSREKIKVKACKEGNTAI
HHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEE
LEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLGHSVEIHSEVG
EEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCEEHHHHHHHHHCCCEEEEHHCC
KGTVVRIKFFNV
CCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 8867804 [H]