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The map label for this gene is mtnN [H]

Identifier: 49185396

GI number: 49185396

Start: 2385861

End: 2386598

Strand: Direct

Name: mtnN [H]

Synonym: BAS2388

Alternate gene names: 49185396

Gene position: 2385861-2386598 (Clockwise)

Preceding gene: 49185395

Following gene: 49185397

Centisome position: 45.63

GC content: 35.5

Gene sequence:

>738_bases
ATGACAGTGAGGGAAGTGAAGTTTGTAATGAAACGTATTGCAATCGTAGCTGCTTGGGAACCTGAACTTACGTATTTGCA
TCAATCTTATCCAAGTGAACGCATTGAAAAAAGAGCCGCTTGGGAATTTCATTTTCATACTATAAATGATCTGGAAATTA
TTTCAGTTATAACTGGTGTTGGGAAGGTAAGTTGTGCTAGTTGTGCACAATTATTAATTAGTGAGTTTCAGCCAGATGAG
TTGTTTATGACAGGGATATGCGGGAGTTTATCAACTAAGGTGAAAAATGGTCATATTGTAGTGGCACTAAACGCCATACA
ACACGATGTCACTGCTGCTGGTTCGGGCGAAGATGTTTTTAACTTATATAATGGTAGAACAGCACCTATTGAAACAACAA
AATCGCTTGTAAGAAGAATAAAAAAAATACGATCTTATGATCCGATTCATTTCGGGACATTTTTATCTGGAGATCAACGT
ATCCGTAGTTCAGAAATGAGGTATTTACTCCATACTGTATATGGAGCATTAGCTGTTGATCAAGAAGTCGCAGCTTTTGC
TTATGTATGTCAAATCAATAAGAAGCCTTTTTTATGTTTAAAAGCTGCTTCAGATCAAGCAAATGATAAAACGAAAGAGG
AACAAAAAATATTTAAAATGTTAGCATGTGAACGAGCTTGCGAGCATTTAATTGCTTTTTTACGTGTGTATGAAATCAAT
GTAGTAAATCATAGATAG

Upstream 100 bases:

>100_bases
AAGTAATTTCGAAGAATAAAGAAACAATACGAAATTTATATGAGAAATATAAAGAGTGGATTCCAGATTATAAAAGAGAA
AGCATAGATAAATTATTTAA

Downstream 100 bases:

>100_bases
TAAGAGGGGCTTAATATTGGAAAGTACAAATAAAATAGCTATTTTGGGTGCGAACGGAAAAGCTGGAAAAATTCTTGTAA
ATGAAGCGTTAGAAAAGGGA

Product: S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: 5'-methylthioadenosine nucleosidase; S-adenosylhomocysteine nucleosidase [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MTVREVKFVMKRIAIVAAWEPELTYLHQSYPSERIEKRAAWEFHFHTINDLEIISVITGVGKVSCASCAQLLISEFQPDE
LFMTGICGSLSTKVKNGHIVVALNAIQHDVTAAGSGEDVFNLYNGRTAPIETTKSLVRRIKKIRSYDPIHFGTFLSGDQR
IRSSEMRYLLHTVYGALAVDQEVAAFAYVCQINKKPFLCLKAASDQANDKTKEEQKIFKMLACERACEHLIAFLRVYEIN
VVNHR

Sequences:

>Translated_245_residues
MTVREVKFVMKRIAIVAAWEPELTYLHQSYPSERIEKRAAWEFHFHTINDLEIISVITGVGKVSCASCAQLLISEFQPDE
LFMTGICGSLSTKVKNGHIVVALNAIQHDVTAAGSGEDVFNLYNGRTAPIETTKSLVRRIKKIRSYDPIHFGTFLSGDQR
IRSSEMRYLLHTVYGALAVDQEVAAFAYVCQINKKPFLCLKAASDQANDKTKEEQKIFKMLACERACEHLIAFLRVYEIN
VVNHR
>Mature_244_residues
TVREVKFVMKRIAIVAAWEPELTYLHQSYPSERIEKRAAWEFHFHTINDLEIISVITGVGKVSCASCAQLLISEFQPDEL
FMTGICGSLSTKVKNGHIVVALNAIQHDVTAAGSGEDVFNLYNGRTAPIETTKSLVRRIKKIRSYDPIHFGTFLSGDQRI
RSSEMRYLLHTVYGALAVDQEVAAFAYVCQINKKPFLCLKAASDQANDKTKEEQKIFKMLACERACEHLIAFLRVYEINV
VNHR

Specific function: Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=209, Percent_Identity=26.7942583732057, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 27713; Mature: 27582

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVREVKFVMKRIAIVAAWEPELTYLHQSYPSERIEKRAAWEFHFHTINDLEIISVITGV
CCHHHHHHHHHHHHHHEECCCHHHHHHHCCCHHHHHHHHCEEEEEEECCCHHHHHHHHCC
GKVSCASCAQLLISEFQPDELFMTGICGSLSTKVKNGHIVVALNAIQHDVTAAGSGEDVF
CCCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHEECCCEEEEEEECHHHHHHCCCCCCHHH
NLYNGRTAPIETTKSLVRRIKKIRSYDPIHFGTFLSGDQRIRSSEMRYLLHTVYGALAVD
HHCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QEVAAFAYVCQINKKPFLCLKAASDQANDKTKEEQKIFKMLACERACEHLIAFLRVYEIN
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
VVNHR
EECCC
>Mature Secondary Structure 
TVREVKFVMKRIAIVAAWEPELTYLHQSYPSERIEKRAAWEFHFHTINDLEIISVITGV
CHHHHHHHHHHHHHHEECCCHHHHHHHCCCHHHHHHHHCEEEEEEECCCHHHHHHHHCC
GKVSCASCAQLLISEFQPDELFMTGICGSLSTKVKNGHIVVALNAIQHDVTAAGSGEDVF
CCCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHEECCCEEEEEEECHHHHHHCCCCCCHHH
NLYNGRTAPIETTKSLVRRIKKIRSYDPIHFGTFLSGDQRIRSSEMRYLLHTVYGALAVD
HHCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QEVAAFAYVCQINKKPFLCLKAASDQANDKTKEEQKIFKMLACERACEHLIAFLRVYEIN
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
VVNHR
EECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9332349; 9665876 [H]