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The map label for this gene is kamA [H]

Identifier: 49185154

GI number: 49185154

Start: 2147670

End: 2149091

Strand: Direct

Name: kamA [H]

Synonym: BAS2145

Alternate gene names: 49185154

Gene position: 2147670-2149091 (Clockwise)

Preceding gene: 49185153

Following gene: 49185155

Centisome position: 41.07

GC content: 37.69

Gene sequence:

>1422_bases
ATGTTACATGATGTATACAAACCAAATCGTCACTGGAAGGATATCGAATTATGGAAAGATGTTACTGAAGAGCAATGGAA
TGATTGGGTTTGGCAATTAACGAATACGATCAAAACGTTAGATGACTTAAAGAAAGTGATTAACTTAACACCGGATGAAG
AAGAGGGCGTTAAAATTTCAACGAAAACGATCCCGTTAAATATTACACCGTACTATGCTTGGTTAATGAATCCTGATGAC
CCACGCTGTCCGATTCGGATGCAATCTGTACCGATCTCGGAAGAGTTATATAAAACAAAATATGATTTAGAAGATCCGCT
TCATGAAGATGAAGATTCTCCAGTTCCAGGGTTGACACATCGTTATCCTGACCGTGTATTATTCTTAGTAACGAATCAAT
GTTCTATGTATTGTCGTTACTGTACACGCCGCCGTTTTAGTGGACAAATTGGAATGGGTGTGCCGAAGAAACAATTAGAT
GATGCAATTGCTTACATTCGTGAAACACCACAAGTACGAGATGTATTAATCTCTGGTGGCGACGGTCTTCTAATTAACGA
TAAAATTTTAGAATATGTATTAAAAAATTTACGAGAGATTCCACATGTCGAGATTATTCGTATCGGTACGAGAGCGCCGG
TAGTATTCCCGCAGCGTATTACAGAAAACCTATGTAACATTATTAAAAAATATCATCCAGTATGGTTAAATACACATTTC
AATACATCTATTGAAATTACTGAAGAATCGAAAAAAGCATGTGAAATGTTAGCCAATGCTGGTGTTCCAGTCGGAAACCA
AGCCGTAATTTTAGCTGGTATTAACGACAGCGTTCCAATTATGAAAAAACTAATGCATGACTTAGTAAAAATCCGTGTAC
GTCCATACTACATTTATCAATGTGACTTATCTGAAGGTATTGGCCATTTCCGTGCACCAGTTTCTAAAGGTCTTGAAATT
ATTGAAGGTTTACGCGGACATACGTCTGGTTATGCAGTACCAACATTCGTTGTTGATGCACCAGGAGGAGGCGGTAAAAT
TGCGCTTCAGCCAAACTATTTAATCTCGCAAAGTGCAGATAAAGTTGTACTTCGTAACTTTGAAGGTGTTATTACAACGT
ATCCAGAGCCAGAAAGCTACATTCCAGGAAGAGCAGAAGGATACTTTAAAGAAATCTATCCAAACTACGAAGAAAAACGT
TCAGATGTTGGTATCGCGGGTCTTATGAGCGACAAGAAATTTAATCTTGTTCCAGACGATTTACAGCGTATGAACCGTCG
TAAAGACTATGAGGATAATGAAACGCATGCAACATTAAAAGATAAACGTGATAAGCGCGACCAATTGAAAGATAAAAAAT
ATCAAGCACAAATGGCTAAATTAGAAGAAAACGACAAAAAAACTGAGGGTGATGCAGTATGA

Upstream 100 bases:

>100_bases
TTATGTAATAGGGTTCTCCGCACATTTACTTATCAATAAAGTAAAGTTGGCATAACTATTGCTTATATAAAGGATGAGCG
TATAAAAAGGGGGAATAGCA

Downstream 100 bases:

>100_bases
ATTGTATGTGGTGTGACAGTACAGAAGCAAAAGAAAGCTTAAATACTGTATATTGGGAATTACCAGATGGTACGAAAGCC
ATTGAAATCCAAGAGACACC

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MLHDVYKPNRHWKDIELWKDVTEEQWNDWVWQLTNTIKTLDDLKKVINLTPDEEEGVKISTKTIPLNITPYYAWLMNPDD
PRCPIRMQSVPISEELYKTKYDLEDPLHEDEDSPVPGLTHRYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLD
DAIAYIRETPQVRDVLISGGDGLLINDKILEYVLKNLREIPHVEIIRIGTRAPVVFPQRITENLCNIIKKYHPVWLNTHF
NTSIEITEESKKACEMLANAGVPVGNQAVILAGINDSVPIMKKLMHDLVKIRVRPYYIYQCDLSEGIGHFRAPVSKGLEI
IEGLRGHTSGYAVPTFVVDAPGGGGKIALQPNYLISQSADKVVLRNFEGVITTYPEPESYIPGRAEGYFKEIYPNYEEKR
SDVGIAGLMSDKKFNLVPDDLQRMNRRKDYEDNETHATLKDKRDKRDQLKDKKYQAQMAKLEENDKKTEGDAV

Sequences:

>Translated_473_residues
MLHDVYKPNRHWKDIELWKDVTEEQWNDWVWQLTNTIKTLDDLKKVINLTPDEEEGVKISTKTIPLNITPYYAWLMNPDD
PRCPIRMQSVPISEELYKTKYDLEDPLHEDEDSPVPGLTHRYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLD
DAIAYIRETPQVRDVLISGGDGLLINDKILEYVLKNLREIPHVEIIRIGTRAPVVFPQRITENLCNIIKKYHPVWLNTHF
NTSIEITEESKKACEMLANAGVPVGNQAVILAGINDSVPIMKKLMHDLVKIRVRPYYIYQCDLSEGIGHFRAPVSKGLEI
IEGLRGHTSGYAVPTFVVDAPGGGGKIALQPNYLISQSADKVVLRNFEGVITTYPEPESYIPGRAEGYFKEIYPNYEEKR
SDVGIAGLMSDKKFNLVPDDLQRMNRRKDYEDNETHATLKDKRDKRDQLKDKKYQAQMAKLEENDKKTEGDAV
>Mature_473_residues
MLHDVYKPNRHWKDIELWKDVTEEQWNDWVWQLTNTIKTLDDLKKVINLTPDEEEGVKISTKTIPLNITPYYAWLMNPDD
PRCPIRMQSVPISEELYKTKYDLEDPLHEDEDSPVPGLTHRYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLD
DAIAYIRETPQVRDVLISGGDGLLINDKILEYVLKNLREIPHVEIIRIGTRAPVVFPQRITENLCNIIKKYHPVWLNTHF
NTSIEITEESKKACEMLANAGVPVGNQAVILAGINDSVPIMKKLMHDLVKIRVRPYYIYQCDLSEGIGHFRAPVSKGLEI
IEGLRGHTSGYAVPTFVVDAPGGGGKIALQPNYLISQSADKVVLRNFEGVITTYPEPESYIPGRAEGYFKEIYPNYEEKR
SDVGIAGLMSDKKFNLVPDDLQRMNRRKDYEDNETHATLKDKRDKRDQLKDKKYQAQMAKLEENDKKTEGDAV

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=324, Percent_Identity=31.4814814814815, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR006638
- InterPro:   IPR022459 [H]

Pfam domain/function: NA

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 54397; Mature: 54397

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHDVYKPNRHWKDIELWKDVTEEQWNDWVWQLTNTIKTLDDLKKVINLTPDEEEGVKIS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
TKTIPLNITPYYAWLMNPDDPRCPIRMQSVPISEELYKTKYDLEDPLHEDEDSPVPGLTH
EEEEEEEECCEEEEEECCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLDDAIAYIRETPQVRDVLISGG
CCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHEEEEECC
DGLLINDKILEYVLKNLREIPHVEIIRIGTRAPVVFPQRITENLCNIIKKYHPVWLNTHF
CCEEECHHHHHHHHHHHHHCCCEEEEEECCCCCEECHHHHHHHHHHHHHHCCCEEEEECC
NTSIEITEESKKACEMLANAGVPVGNQAVILAGINDSVPIMKKLMHDLVKIRVRPYYIYQ
CCEEEEECHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHEEECEEEEEE
CDLSEGIGHFRAPVSKGLEIIEGLRGHTSGYAVPTFVVDAPGGGGKIALQPNYLISQSAD
ECHHHCCHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCEEEECCCHHCCCCCC
KVVLRNFEGVITTYPEPESYIPGRAEGYFKEIYPNYEEKRSDVGIAGLMSDKKFNLVPDD
HHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHCCCHHHHHCCCCEEEECCCCCCCCCCHH
LQRMNRRKDYEDNETHATLKDKRDKRDQLKDKKYQAQMAKLEENDKKTEGDAV
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLHDVYKPNRHWKDIELWKDVTEEQWNDWVWQLTNTIKTLDDLKKVINLTPDEEEGVKIS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
TKTIPLNITPYYAWLMNPDDPRCPIRMQSVPISEELYKTKYDLEDPLHEDEDSPVPGLTH
EEEEEEEECCEEEEEECCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RYPDRVLFLVTNQCSMYCRYCTRRRFSGQIGMGVPKKQLDDAIAYIRETPQVRDVLISGG
CCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHEEEEECC
DGLLINDKILEYVLKNLREIPHVEIIRIGTRAPVVFPQRITENLCNIIKKYHPVWLNTHF
CCEEECHHHHHHHHHHHHHCCCEEEEEECCCCCEECHHHHHHHHHHHHHHCCCEEEEECC
NTSIEITEESKKACEMLANAGVPVGNQAVILAGINDSVPIMKKLMHDLVKIRVRPYYIYQ
CCEEEEECHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHEEECEEEEEE
CDLSEGIGHFRAPVSKGLEIIEGLRGHTSGYAVPTFVVDAPGGGGKIALQPNYLISQSAD
ECHHHCCHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCEEEECCCHHCCCCCC
KVVLRNFEGVITTYPEPESYIPGRAEGYFKEIYPNYEEKRSDVGIAGLMSDKKFNLVPDD
HHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHCCCHHHHHCCCCEEEECCCCCCCCCCHH
LQRMNRRKDYEDNETHATLKDKRDKRDQLKDKKYQAQMAKLEENDKKTEGDAV
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377; 10839984 [H]