Click here to switch to the map view.

The map label for this gene is czcD [H]

Identifier: 49184643

GI number: 49184643

Start: 1646276

End: 1647175

Strand: Direct

Name: czcD [H]

Synonym: BAS1629

Alternate gene names: 49184643

Gene position: 1646276-1647175 (Clockwise)

Preceding gene: 49184641

Following gene: 49184646

Centisome position: 31.49

GC content: 36.0

Gene sequence:

>900_bases
ATGGGACATTCGCATAATCATGGGCATTCTAAAAATAAAAAAGCGTTGCTACTTGCATTCTTACTAACAACAAGTTTTAT
GATTGCTGAAGTTATTGGGGGATTTGTAACAAATAGTTTAGCACTACTATCTGACGCGGGGCATATGTTAAGTGATGCGG
TATCTTTAGCTTTAAGTTTACTTGCGTTTAAGCTAGGAGAAAAAACAGCAACAGCTGCGAAAACATACGGGTATAAGCGA
GTCGAAATGTTAGCGGCATTATGTAACGGTGTCGTTCTTATTGTCGTTTCAGTATACATTTTTATTGAAGCAATTCGCCG
TTTTAAAGAACCAGTTGAGATTGCTAGTAATGGGATGCTCATTATTGCTGTACTTGGTCTGCTTATTAATATTTTATCAG
CTTGGATATTAATGAGAGGCGGAGATGTAAAGGGGAATTTGAATTTAAGGAGTGCTTTCCTACACGTATTAGGCGATTTA
TTAGGATCCGTCGGAGCGATTATTGCTGCGTTACTTATTAAATTTTTTGGATGGACTGCTGCAGATGCGATTGCTAGTAT
TCTTGTGTCTATTTTAGTCATTATTAGTGGATGGCGTGTAACACGTGATACAGTCCATATATTAATGGAAGGTGCACCAC
AGCACATAAATGTTGAAGAGGTAAAAAGTACATTATTAAATATTACGGTTGTAAAAGAAGTTCATGATTTGCACATATGG
TCTGTCACATCGGATTTTCAAGTATTAACTTGCCACTTGATTATTAAAGGAAATGAAACACAAAGTGTATTAAAAGAGGC
TACGGAAGTATTAAAAGAGAAGTTTCATGTAGAACATGTCACCATTCAAGTAGAAATAGATGGTGAATTTCATCATAGTG
AGACAACTTGCAAAGTATGA

Upstream 100 bases:

>100_bases
TTTGAAAAGTATCGAAGTGTGTATACAGAGGAAGCGGGATAAAGATAGGGAATTTGTTTCATACTAATGTACAGATATTG
CACTTAAAGGAGCATTTTGT

Downstream 100 bases:

>100_bases
AAGAAAAAGGATACGAAAAAGTGTCATAACATTTTTCGCGCGGCATACATATATATAATGTGGCCACAAATACTTTGTAA
GGTAAATATTTCATGAAATT

Product: cation efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MGHSHNHGHSKNKKALLLAFLLTTSFMIAEVIGGFVTNSLALLSDAGHMLSDAVSLALSLLAFKLGEKTATAAKTYGYKR
VEMLAALCNGVVLIVVSVYIFIEAIRRFKEPVEIASNGMLIIAVLGLLINILSAWILMRGGDVKGNLNLRSAFLHVLGDL
LGSVGAIIAALLIKFFGWTAADAIASILVSILVIISGWRVTRDTVHILMEGAPQHINVEEVKSTLLNITVVKEVHDLHIW
SVTSDFQVLTCHLIIKGNETQSVLKEATEVLKEKFHVEHVTIQVEIDGEFHHSETTCKV

Sequences:

>Translated_299_residues
MGHSHNHGHSKNKKALLLAFLLTTSFMIAEVIGGFVTNSLALLSDAGHMLSDAVSLALSLLAFKLGEKTATAAKTYGYKR
VEMLAALCNGVVLIVVSVYIFIEAIRRFKEPVEIASNGMLIIAVLGLLINILSAWILMRGGDVKGNLNLRSAFLHVLGDL
LGSVGAIIAALLIKFFGWTAADAIASILVSILVIISGWRVTRDTVHILMEGAPQHINVEEVKSTLLNITVVKEVHDLHIW
SVTSDFQVLTCHLIIKGNETQSVLKEATEVLKEKFHVEHVTIQVEIDGEFHHSETTCKV
>Mature_298_residues
GHSHNHGHSKNKKALLLAFLLTTSFMIAEVIGGFVTNSLALLSDAGHMLSDAVSLALSLLAFKLGEKTATAAKTYGYKRV
EMLAALCNGVVLIVVSVYIFIEAIRRFKEPVEIASNGMLIIAVLGLLINILSAWILMRGGDVKGNLNLRSAFLHVLGDLL
GSVGAIIAALLIKFFGWTAADAIASILVSILVIISGWRVTRDTVHILMEGAPQHINVEEVKSTLLNITVVKEVHDLHIWS
VTSDFQVLTCHLIIKGNETQSVLKEATEVLKEKFHVEHVTIQVEIDGEFHHSETTCKV

Specific function: Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc, cadmium and cobalt, in exchange for potassium and H(+) ions [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI21361112, Length=298, Percent_Identity=33.8926174496644, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI52352805, Length=300, Percent_Identity=32.6666666666667, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI21359890, Length=305, Percent_Identity=34.4262295081967, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI289803013, Length=303, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=8e-33,
Organism=Homo sapiens, GI289803009, Length=303, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=8e-33,
Organism=Homo sapiens, GI289803007, Length=303, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=8e-33,
Organism=Homo sapiens, GI289803003, Length=303, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=8e-33,
Organism=Homo sapiens, GI64762489, Length=303, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=9e-33,
Organism=Homo sapiens, GI20070323, Length=325, Percent_Identity=27.3846153846154, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI14210520, Length=230, Percent_Identity=32.1739130434783, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI52351208, Length=132, Percent_Identity=38.6363636363636, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI52352803, Length=124, Percent_Identity=41.1290322580645, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI222080086, Length=128, Percent_Identity=29.6875, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI40255009, Length=128, Percent_Identity=29.6875, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786966, Length=278, Percent_Identity=46.4028776978417, Blast_Score=206, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17555794, Length=318, Percent_Identity=36.1635220125786, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17555796, Length=314, Percent_Identity=35.6687898089172, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI193210990, Length=326, Percent_Identity=33.4355828220859, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI32564488, Length=312, Percent_Identity=28.2051282051282, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17550442, Length=130, Percent_Identity=30, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17550440, Length=130, Percent_Identity=30, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6320411, Length=180, Percent_Identity=38.8888888888889, Blast_Score=105, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6323899, Length=122, Percent_Identity=39.344262295082, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324892, Length=123, Percent_Identity=39.8373983739837, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24583858, Length=338, Percent_Identity=31.0650887573964, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24656728, Length=339, Percent_Identity=30.9734513274336, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24656724, Length=339, Percent_Identity=30.9734513274336, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24656720, Length=339, Percent_Identity=30.9734513274336, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24656715, Length=339, Percent_Identity=30.9734513274336, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21357035, Length=339, Percent_Identity=30.9734513274336, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24585900, Length=150, Percent_Identity=38, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24585898, Length=150, Percent_Identity=38, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24585896, Length=150, Percent_Identity=38, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI19921672, Length=150, Percent_Identity=38, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24584409, Length=142, Percent_Identity=33.0985915492958, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28574430, Length=142, Percent_Identity=33.0985915492958, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24645863, Length=139, Percent_Identity=30.9352517985612, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 32545; Mature: 32414

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHSHNHGHSKNKKALLLAFLLTTSFMIAEVIGGFVTNSLALLSDAGHMLSDAVSLALSL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAFKLGEKTATAAKTYGYKRVEMLAALCNGVVLIVVSVYIFIEAIRRFKEPVEIASNGML
HHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
IIAVLGLLINILSAWILMRGGDVKGNLNLRSAFLHVLGDLLGSVGAIIAALLIKFFGWTA
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
ADAIASILVSILVIISGWRVTRDTVHILMEGAPQHINVEEVKSTLLNITVVKEVHDLHIW
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEE
SVTSDFQVLTCHLIIKGNETQSVLKEATEVLKEKFHVEHVTIQVEIDGEFHHSETTCKV
EECCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCEEEEEEEEEECCCEECCCCCCCC
>Mature Secondary Structure 
GHSHNHGHSKNKKALLLAFLLTTSFMIAEVIGGFVTNSLALLSDAGHMLSDAVSLALSL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAFKLGEKTATAAKTYGYKRVEMLAALCNGVVLIVVSVYIFIEAIRRFKEPVEIASNGML
HHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
IIAVLGLLINILSAWILMRGGDVKGNLNLRSAFLHVLGDLLGSVGAIIAALLIKFFGWTA
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
ADAIASILVSILVIISGWRVTRDTVHILMEGAPQHINVEEVKSTLLNITVVKEVHDLHIW
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEE
SVTSDFQVLTCHLIIKGNETQSVLKEATEVLKEKFHVEHVTIQVEIDGEFHHSETTCKV
EECCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCEEEEEEEEEECCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA