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The map label for this gene is hepT [H]

Identifier: 49184441

GI number: 49184441

Start: 1449868

End: 1450839

Strand: Direct

Name: hepT [H]

Synonym: BAS1424

Alternate gene names: 49184441

Gene position: 1449868-1450839 (Clockwise)

Preceding gene: 49184440

Following gene: 49184442

Centisome position: 27.73

GC content: 36.52

Gene sequence:

>972_bases
GTGAACAATATGAAGTTACAACTTATGTACTCTTTTTTACGATCGGATATTAATGTGATAGAAAAAGAATTAAAAAAGAC
AGTTGCTTCTGAACAGCCATTAGTAGAAGAGGCGGCATTACAACTTATTGAAGCTGGTGGGAAGCGAATTCGTCCTGTAT
TTGTGTTGCTTGCGGGGAAATTTGGAGATTATAAGTTAGATGCAATTAAGCATGTAGCTGTTGCGTTAGAACTTATTCAT
ATGGCTTCTCTTGTTCACGATGATGTTATTGATGCTGCGTTTTTACGACGTGGTAGTGCAACTGTGAATGCGAAATGGGG
AGATCGTATTGCAATGTATACAGGGGACTATTTATTCGCTAAGTCTCTTGAATGTATAACGAATATTGAAATTCCAGAGG
CGCATCAGGCGCTATCGCATACCATTTTAGAAGTTTGTAAAGGTGAAATCGAACAAATAAAAGATAAGTATAACTATGAC
CAAAATTTAAGAACATATTTAAGAAGAATAAAGCGAAAAACCGCTTTATTAATTGCTGCAAGTTGCCAACTAGGAGCGAT
TGCTGCTGGCGCTAATCGTGATACGGTAAGTCGTCTGTTTTGGTATGGCTATTTCGTAGGGATGTCGTATCAAATTATTG
ATGACATTTTAGACTTCGTTTCTACAGAAGAGAAACTTGGAAAACCTGCTGGTGGTGATTTATTGCAAGGAAACATTACG
CTTCCTGCCCTATATGCTATGGAAGATCCAATCCTTTGTAAGAAAATCAGATCTGTACATGAAAATACAACAGCGGACGA
AATGAAAGAAATTATTGAAGCTGTAAAGAATAGTGCTGCTATTGATAAAGCATTTGCGTTTAGTGAACGTTATTTACATA
AAGCATTAGAAATGATAAAACCACTCCCACGTGGACAAGCGAAGTATGCATTACAAAATGTAGCAAAGTATATTGGAAAA
CGAAAATTTTAG

Upstream 100 bases:

>100_bases
CTTGAACGTGTGCAAGTGAAGCCATTTACTTTTGGGGTAGCAGCGATGCATTTAGGCATGAAACCAGAATCAAAATAGAA
AAAAGAAGTTTTAGGTTAAG

Downstream 100 bases:

>100_bases
TGTTTTTTCTAAAAAATAAAATAATCTCTCTATTTCAAAACTATTGCACAATTGTGATAAGGGTGTTAATATGTGTGTGG
GGATATACAATTACATACAT

Product: heptaprenyl diphosphate synthase component II

Products: NA

Alternate protein names: HEPPP synthase subunit 2; Spore germination protein C3 [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MNNMKLQLMYSFLRSDINVIEKELKKTVASEQPLVEEAALQLIEAGGKRIRPVFVLLAGKFGDYKLDAIKHVAVALELIH
MASLVHDDVIDAAFLRRGSATVNAKWGDRIAMYTGDYLFAKSLECITNIEIPEAHQALSHTILEVCKGEIEQIKDKYNYD
QNLRTYLRRIKRKTALLIAASCQLGAIAAGANRDTVSRLFWYGYFVGMSYQIIDDILDFVSTEEKLGKPAGGDLLQGNIT
LPALYAMEDPILCKKIRSVHENTTADEMKEIIEAVKNSAAIDKAFAFSERYLHKALEMIKPLPRGQAKYALQNVAKYIGK
RKF

Sequences:

>Translated_323_residues
MNNMKLQLMYSFLRSDINVIEKELKKTVASEQPLVEEAALQLIEAGGKRIRPVFVLLAGKFGDYKLDAIKHVAVALELIH
MASLVHDDVIDAAFLRRGSATVNAKWGDRIAMYTGDYLFAKSLECITNIEIPEAHQALSHTILEVCKGEIEQIKDKYNYD
QNLRTYLRRIKRKTALLIAASCQLGAIAAGANRDTVSRLFWYGYFVGMSYQIIDDILDFVSTEEKLGKPAGGDLLQGNIT
LPALYAMEDPILCKKIRSVHENTTADEMKEIIEAVKNSAAIDKAFAFSERYLHKALEMIKPLPRGQAKYALQNVAKYIGK
RKF
>Mature_323_residues
MNNMKLQLMYSFLRSDINVIEKELKKTVASEQPLVEEAALQLIEAGGKRIRPVFVLLAGKFGDYKLDAIKHVAVALELIH
MASLVHDDVIDAAFLRRGSATVNAKWGDRIAMYTGDYLFAKSLECITNIEIPEAHQALSHTILEVCKGEIEQIKDKYNYD
QNLRTYLRRIKRKTALLIAASCQLGAIAAGANRDTVSRLFWYGYFVGMSYQIIDDILDFVSTEEKLGKPAGGDLLQGNIT
LPALYAMEDPILCKKIRSVHENTTADEMKEIIEAVKNSAAIDKAFAFSERYLHKALEMIKPLPRGQAKYALQNVAKYIGK
RKF

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=314, Percent_Identity=28.9808917197452, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI169808399, Length=324, Percent_Identity=22.8395061728395, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789578, Length=321, Percent_Identity=29.595015576324, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1786623, Length=250, Percent_Identity=30.4, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17505681, Length=314, Percent_Identity=33.4394904458599, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319475, Length=300, Percent_Identity=29.6666666666667, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24651612, Length=306, Percent_Identity=28.7581699346405, Blast_Score=148, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 36307; Mature: 36307

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNMKLQLMYSFLRSDINVIEKELKKTVASEQPLVEEAALQLIEAGGKRIRPVFVLLAGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHCHHHEEEECC
FGDYKLDAIKHVAVALELIHMASLVHDDVIDAAFLRRGSATVNAKWGDRIAMYTGDYLFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEECCHHHH
KSLECITNIEIPEAHQALSHTILEVCKGEIEQIKDKYNYDQNLRTYLRRIKRKTALLIAA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEE
SCQLGAIAAGANRDTVSRLFWYGYFVGMSYQIIDDILDFVSTEEKLGKPAGGDLLQGNIT
CCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEECCCC
LPALYAMEDPILCKKIRSVHENTTADEMKEIIEAVKNSAAIDKAFAFSERYLHKALEMIK
CCCHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLPRGQAKYALQNVAKYIGKRKF
CCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNNMKLQLMYSFLRSDINVIEKELKKTVASEQPLVEEAALQLIEAGGKRIRPVFVLLAGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHCHHHEEEECC
FGDYKLDAIKHVAVALELIHMASLVHDDVIDAAFLRRGSATVNAKWGDRIAMYTGDYLFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEECCHHHH
KSLECITNIEIPEAHQALSHTILEVCKGEIEQIKDKYNYDQNLRTYLRRIKRKTALLIAA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEE
SCQLGAIAAGANRDTVSRLFWYGYFVGMSYQIIDDILDFVSTEEKLGKPAGGDLLQGNIT
CCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEECCCC
LPALYAMEDPILCKKIRSVHENTTADEMKEIIEAVKNSAAIDKAFAFSERYLHKALEMIK
CCCHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLPRGQAKYALQNVAKYIGKRKF
CCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033 [H]