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The map label for this gene is resA

Identifier: 49184400

GI number: 49184400

Start: 1413882

End: 1414403

Strand: Direct

Name: resA

Synonym: BAS1383

Alternate gene names: 49184400

Gene position: 1413882-1414403 (Clockwise)

Preceding gene: 49184399

Following gene: 49184401

Centisome position: 27.04

GC content: 33.91

Gene sequence:

>522_bases
ATGAAGAAAAATCGCTTATTATTTCGCGTTATCATTCTGCTCATTTTAAGCGGTGCTGTAGGATTTACACTTTATCAAGG
ATTCTTTGCTGATAAAGAGAAAATGCAAATTGGAAAAGAAGCGCCTAACTTTGTTGTGACGGATTTAGAAGGAAAGAAAA
TTGAACTAAAAGATTTAAAGGGAAAAGGTGTATTTTTAAATTTTTGGGGTACGTGGTGTAAACCTTGTGAGAAAGAAATG
CCTTATATGAATGAACTATACCCAAAGTATAAAGAAAAAGGCGTTGAAATTATTGCGTTAGATGCAGATGAGACGGACAT
CGCAGTAAAGAATTTTGTGAACCAATACGGTTTGAAATTCCCAGTTGCCATTGATAAAGGACAAAAAATTATAGGAACAT
ACGGAGTAGGACCATTACCAACAAGCTTCTTGATTGATAAAGATGGAAAAGTAGTGGAGCAAATTATAGGTGAACAAACG
AAAGAACAGTTAGAAGGATATTTAAAGAAAATTACTCCGTAA

Upstream 100 bases:

>100_bases
CGCTAATCGATATTGTGAAACTTTCACCAGTGGAATGTTCCGCTGGTGATTTATTAAAAAATACATATATTCATCACTCG
TCGAAGAGAGGGGAAACAAT

Downstream 100 bases:

>100_bases
TAAAGAAAGCCTTTACATAAGAGGTGCGTGTCTATAGTGCCTCTGGTTTAAAAATTCTGAGTATTGCGGTAACTTGAGGT
TAGAATATACAATAGTACAT

Product: thiol-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MKKNRLLFRVIILLILSGAVGFTLYQGFFADKEKMQIGKEAPNFVVTDLEGKKIELKDLKGKGVFLNFWGTWCKPCEKEM
PYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKFPVAIDKGQKIIGTYGVGPLPTSFLIDKDGKVVEQIIGEQT
KEQLEGYLKKITP

Sequences:

>Translated_173_residues
MKKNRLLFRVIILLILSGAVGFTLYQGFFADKEKMQIGKEAPNFVVTDLEGKKIELKDLKGKGVFLNFWGTWCKPCEKEM
PYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKFPVAIDKGQKIIGTYGVGPLPTSFLIDKDGKVVEQIIGEQT
KEQLEGYLKKITP
>Mature_173_residues
MKKNRLLFRVIILLILSGAVGFTLYQGFFADKEKMQIGKEAPNFVVTDLEGKKIELKDLKGKGVFLNFWGTWCKPCEKEM
PYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKFPVAIDKGQKIIGTYGVGPLPTSFLIDKDGKVVEQIIGEQT
KEQLEGYLKKITP

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

Organism=Escherichia coli, GI1788523, Length=179, Percent_Identity=26.8156424581006, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RESA_BACAH (A0RBT0)

Other databases:

- EMBL:   CP000485
- RefSeq:   YP_894180.1
- ProteinModelPortal:   A0RBT0
- SMR:   A0RBT0
- STRING:   A0RBT0
- EnsemblBacteria:   EBBACT00000069740
- GeneID:   4546078
- GenomeReviews:   CP000485_GR
- KEGG:   btl:BALH_1330
- eggNOG:   COG0526
- GeneTree:   EBGT00050000000761
- HOGENOM:   HBG493509
- OMA:   TLYQGYF
- ProtClustDB:   PRK03147
- BioCyc:   BTHU412694:BALH_1330-MONOMER
- HAMAP:   MF_01319
- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10

Pfam domain/function: PF00578 AhpC-TSA; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 19587; Mature: 19587

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS00194 THIOREDOXIN_1; PS51352 THIOREDOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10e09f8c)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNRLLFRVIILLILSGAVGFTLYQGFFADKEKMQIGKEAPNFVVTDLEGKKIELKDLK
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHCCCCCCEEEECCCCCEEEEEECC
GKGVFLNFWGTWCKPCEKEMPYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKF
CCEEEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCC
PVAIDKGQKIIGTYGVGPLPTSFLIDKDGKVVEQIIGEQTKEQLEGYLKKITP
EEEECCCCEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MKKNRLLFRVIILLILSGAVGFTLYQGFFADKEKMQIGKEAPNFVVTDLEGKKIELKDLK
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHCCCCCCEEEECCCCCEEEEEECC
GKGVFLNFWGTWCKPCEKEMPYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKF
CCEEEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCC
PVAIDKGQKIIGTYGVGPLPTSFLIDKDGKVVEQIIGEQTKEQLEGYLKKITP
EEEECCCCEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA