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The map label for this gene is uppP

Identifier: 49184313

GI number: 49184313

Start: 1329944

End: 1330735

Strand: Direct

Name: uppP

Synonym: BAS1296

Alternate gene names: 49184313

Gene position: 1329944-1330735 (Clockwise)

Preceding gene: 49184311

Following gene: 49184316

Centisome position: 25.44

GC content: 37.12

Gene sequence:

>792_bases
GTGGCTGATTGGTTAATTGGTATAATCATGGGTGCTGTTGAAGGGTTAACAGAGTTTTTACCAGTATCATCAACAGGGCA
TATGATTTTAACAGGACATCTAATTGGATTTGACGACGATAGAGCGAAAGTTTTCGAAGTTGTTATTCAATTGGGATCGA
TTTTAGCAGTTGTTGTTATATTTTGGAAACGTTTATGGTCTTTAGTAGGTATAGGGAAAGTAACAGATGGACCATCGTTA
AATTTATTACATATTATTATCGGGATGATTCCAGCCGGCGTACTTGGCGTATTGTTCCATAGTGCGATTAAAGAAGTTTT
ATTTGGGCCAGGCCCAGTTGTTATTAGCTTAGTGGCTGGTGGTATTTTAATGATTGTTGCTGAGAAGTTTTCGAAACCAA
GTACAGCAAGAACATTAGATGAAATCACATATAAACAAGCATTTACAATCGGAATGTTCCAATGTTTAGCGCTTTGGCCA
GGCTTTTCTCGTTCTGGTTCTACAATAAGTGGTGGTTTATTAGCTCGCGTATCACATACAGCGGCAGCTGAATATACATT
TATTTTAGCAGTACCAATGATGGTAGCTGCAAGTGGCTTAGATTTAATTAAAAGCTGGGATATATTAAGTACGGCTGATA
TACCGTTATTTGCAACAGGATTTATTACCGCATTCGTTGTTGCGATGCTTGCAATTGTTTCATTCTTAAAATTACTATCT
CGTGTAAAACTAACACCGTTCGCTTACTACCGTTTCATTTTAGCTGCGGTATTCTATTTCTTCATTATGTAA

Upstream 100 bases:

>100_bases
GCATGTAAATTCAATAAAAAAAGGATGCACTTTAAAAGGGGATAAGGTATTATGATAAGGTGTGAAAAATTACATATTTG
TTATTAAGGAGGCACTACTT

Downstream 100 bases:

>100_bases
TAAAAAAACTGCCGGGTTCGGCAGTTTTTTTATTTTACTACTTTTTCTATCATGCTTTCCATTACATGTTCCCATAGAGA
AGTATCATCAGCTAATGTAG

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 2; Undecaprenyl pyrophosphate phosphatase 2

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MADWLIGIIMGAVEGLTEFLPVSSTGHMILTGHLIGFDDDRAKVFEVVIQLGSILAVVVIFWKRLWSLVGIGKVTDGPSL
NLLHIIIGMIPAGVLGVLFHSAIKEVLFGPGPVVISLVAGGILMIVAEKFSKPSTARTLDEITYKQAFTIGMFQCLALWP
GFSRSGSTISGGLLARVSHTAAAEYTFILAVPMMVAASGLDLIKSWDILSTADIPLFATGFITAFVVAMLAIVSFLKLLS
RVKLTPFAYYRFILAAVFYFFIM

Sequences:

>Translated_263_residues
MADWLIGIIMGAVEGLTEFLPVSSTGHMILTGHLIGFDDDRAKVFEVVIQLGSILAVVVIFWKRLWSLVGIGKVTDGPSL
NLLHIIIGMIPAGVLGVLFHSAIKEVLFGPGPVVISLVAGGILMIVAEKFSKPSTARTLDEITYKQAFTIGMFQCLALWP
GFSRSGSTISGGLLARVSHTAAAEYTFILAVPMMVAASGLDLIKSWDILSTADIPLFATGFITAFVVAMLAIVSFLKLLS
RVKLTPFAYYRFILAAVFYFFIM
>Mature_262_residues
ADWLIGIIMGAVEGLTEFLPVSSTGHMILTGHLIGFDDDRAKVFEVVIQLGSILAVVVIFWKRLWSLVGIGKVTDGPSLN
LLHIIIGMIPAGVLGVLFHSAIKEVLFGPGPVVISLVAGGILMIVAEKFSKPSTARTLDEITYKQAFTIGMFQCLALWPG
FSRSGSTISGGLLARVSHTAAAEYTFILAVPMMVAASGLDLIKSWDILSTADIPLFATGFITAFVVAMLAIVSFLKLLSR
VKLTPFAYYRFILAAVFYFFIM

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=268, Percent_Identity=61.9402985074627, Blast_Score=309, Evalue=1e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP2_BACAN (Q81T84)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_843860.2
- RefSeq:   YP_018024.2
- RefSeq:   YP_027565.1
- EnsemblBacteria:   EBBACT00000011991
- EnsemblBacteria:   EBBACT00000015251
- EnsemblBacteria:   EBBACT00000024319
- GeneID:   1087239
- GeneID:   2816431
- GeneID:   2849908
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_1403
- KEGG:   bar:GBAA_1403
- KEGG:   bat:BAS1296
- TIGR:   BA_1403
- TIGR:   GBAA_1403
- GeneTree:   EBGT00050000002490
- HOGENOM:   HBG391969
- OMA:   DWLIGLI
- ProtClustDB:   PRK00281
- BioCyc:   BANT260799:BAS1296-MONOMER
- BioCyc:   BANT261594:GBAA1403-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 28363; Mature: 28232

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10cf74c0)-; HASH(0x1054a664)-; HASH(0x10b40224)-; HASH(0xf5fe238)-; HASH(0x105d0160)-; HASH(0x10c617e4)-; HASH(0xf3d63ec)-; HASH(0x1129fcd4)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADWLIGIIMGAVEGLTEFLPVSSTGHMILTGHLIGFDDDRAKVFEVVIQLGSILAVVVI
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
FWKRLWSLVGIGKVTDGPSLNLLHIIIGMIPAGVLGVLFHSAIKEVLFGPGPVVISLVAG
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GILMIVAEKFSKPSTARTLDEITYKQAFTIGMFQCLALWPGFSRSGSTISGGLLARVSHT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
AAAEYTFILAVPMMVAASGLDLIKSWDILSTADIPLFATGFITAFVVAMLAIVSFLKLLS
HHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RVKLTPFAYYRFILAAVFYFFIM
HHCCCHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure 
ADWLIGIIMGAVEGLTEFLPVSSTGHMILTGHLIGFDDDRAKVFEVVIQLGSILAVVVI
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
FWKRLWSLVGIGKVTDGPSLNLLHIIIGMIPAGVLGVLFHSAIKEVLFGPGPVVISLVAG
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GILMIVAEKFSKPSTARTLDEITYKQAFTIGMFQCLALWPGFSRSGSTISGGLLARVSHT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
AAAEYTFILAVPMMVAASGLDLIKSWDILSTADIPLFATGFITAFVVAMLAIVSFLKLLS
HHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RVKLTPFAYYRFILAAVFYFFIM
HHCCCHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629