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The map label for this gene is inlA [H]

Identifier: 49184263

GI number: 49184263

Start: 1287792

End: 1289420

Strand: Direct

Name: inlA [H]

Synonym: BAS1246

Alternate gene names: 49184263

Gene position: 1287792-1289420 (Clockwise)

Preceding gene: 49184262

Following gene: 49184264

Centisome position: 24.63

GC content: 32.11

Gene sequence:

>1629_bases
TTGTTTTTAAATACGAATGAGATTCTTGATTATAGTGCATTAAAATATATGCCAAATTTGAAATCTTTAACAGTTGCGAA
TGCGAAGATAAAAGATCCGTCGTTCTTTGCGAACTTAAAGCAATTAAATCATTTAGCTTTGCGTGGTAATGAATTTTCAG
ATGTAACACCACTTGTTAAGATGGATCATTTAGATTCTCTTGATTTAAGTAATAATAAAATTACAAACGTTGCACCACTA
ATTGAAATGAAAAATGTAAAAAGTTTATATTTATCAGGTAACCAAATAGAAGATGTAACAGCATTAGCGAAAATGGAACA
ACTAGATTATTTGAATTTAGCGAATAATAAAATTACGAATGTTGCTCCATTAAGCGCGTTAAAAAATGTAACATACTTGA
CTTTAGCTGGTAATCAAATTGAAGATATTAAACCGTTATATTCATTACCTTTAACAGACTTAGTATTAACACGTAATAAA
GTTAAAGATTTATCCGGCATTGAGCAAATGAAGCAATTAGAAGAATTGTGGATCGGGAAAAATGAAATAAAAGATGTTAC
TCCTCTAAGTAAGATGACACAGTTAAAACAATTACACCTACCTAACAATGAGTTAAAGGATATTACGCCATTATCAAGTC
TAGTAAACTTACAAAAACTTGATTTAGAAGCAAATTATATTTCAGACTTAACACCGGCTAGTAATTTGAAAAAGTTAGTA
TTCTTAAGTTTTGTTGCAAATGAAATTCGTGATGTTCGACCAGTGATAGAACTAAGTAAAACAGCCTACATCAATGTTCA
AAATCAAAAAGTATTTTTAGAGGAAACAGAAGTAAATAAAGAAGTAAAAGTACCTATATACGAAAAAGACGGTAAAATCT
CTACAAAAATTCGTTTGAAGGGCGAAGGTGGTACGTATAGTAACGATGCAGTTAAGTGGAGTACACCAGGTGAGAAAGTA
TATGAATTTGGTGTGAAAGATCCATTTGCGGATACAGGAATCTTCTTTACGGGATCTGTCATTCAAAATGTGGTAGAAAG
CAAAGCGGATAACACTTCTAAAGAAGACAATACTTCTAAAGAAGATGCAAAAGTAGAAGTAGTGGAATTTAAAGATGTAC
CAAAAGGACATTGGTCAGAAGAAGCAATTCATTATTTAGCGAAAGAAAATATTTTCAAGGGATATGGAAATGGACAATTT
GGATTTGGGGATAGTATTACTCGCGGACAAGTTGCGTCTTTAGTACAAAGGTACTTGAAATTAGAAAATAAAGTAGAGCA
GAAAGAGAGATTTACAGATACGAAAGGACATATGTTTGAGCAAGATATTGCTACAGTTGCGCAAGCTGGAATTATGCAAG
GAGATGGTACTGGGGAGTTTCGTCCAGATGGAGTATTAACTCGATACGAAATGTCTGTAGTATTATATAAAGTATTTCAG
TTAAAAGAAGATGGAAATAATAAAGTGAACTTTAAAGATGTACCAACTGGTCATTGGGCAGAAGGGTATGTGAAAGCGTT
AGTGGATAATAACATATCAAAAGGTGATGGAAAAGAACGCTTTTTAGGTGATGATTTTGTAACACGTGAACAATATGCAC
AGTTTTTATATAACGCAATAACGAAATAA

Upstream 100 bases:

>100_bases
ACAGATAACAAGTTAAGGGAACTTGTTAATAAAAAAGTATTTAATAGAAAAGATGTAAATACACCCGATTACGAAAGAAG
AGTTATTACAAGTAAAGAAT

Downstream 100 bases:

>100_bases
AAGATGAGAAAATACGTTATTCTTTCATTGGGAAAGAATAACGTATTTTTTATGTATAAAATGAACTAGTCAATATACAG
GAGTATAGACATATGAATGG

Product: internalin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MFLNTNEILDYSALKYMPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFSDVTPLVKMDHLDSLDLSNNKITNVAPL
IEMKNVKSLYLSGNQIEDVTALAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLAGNQIEDIKPLYSLPLTDLVLTRNK
VKDLSGIEQMKQLEELWIGKNEIKDVTPLSKMTQLKQLHLPNNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLV
FLSFVANEIRDVRPVIELSKTAYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLKGEGGTYSNDAVKWSTPGEKV
YEFGVKDPFADTGIFFTGSVIQNVVESKADNTSKEDNTSKEDAKVEVVEFKDVPKGHWSEEAIHYLAKENIFKGYGNGQF
GFGDSITRGQVASLVQRYLKLENKVEQKERFTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQ
LKEDGNNKVNFKDVPTGHWAEGYVKALVDNNISKGDGKERFLGDDFVTREQYAQFLYNAITK

Sequences:

>Translated_542_residues
MFLNTNEILDYSALKYMPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFSDVTPLVKMDHLDSLDLSNNKITNVAPL
IEMKNVKSLYLSGNQIEDVTALAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLAGNQIEDIKPLYSLPLTDLVLTRNK
VKDLSGIEQMKQLEELWIGKNEIKDVTPLSKMTQLKQLHLPNNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLV
FLSFVANEIRDVRPVIELSKTAYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLKGEGGTYSNDAVKWSTPGEKV
YEFGVKDPFADTGIFFTGSVIQNVVESKADNTSKEDNTSKEDAKVEVVEFKDVPKGHWSEEAIHYLAKENIFKGYGNGQF
GFGDSITRGQVASLVQRYLKLENKVEQKERFTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQ
LKEDGNNKVNFKDVPTGHWAEGYVKALVDNNISKGDGKERFLGDDFVTREQYAQFLYNAITK
>Mature_542_residues
MFLNTNEILDYSALKYMPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFSDVTPLVKMDHLDSLDLSNNKITNVAPL
IEMKNVKSLYLSGNQIEDVTALAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLAGNQIEDIKPLYSLPLTDLVLTRNK
VKDLSGIEQMKQLEELWIGKNEIKDVTPLSKMTQLKQLHLPNNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLV
FLSFVANEIRDVRPVIELSKTAYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLKGEGGTYSNDAVKWSTPGEKV
YEFGVKDPFADTGIFFTGSVIQNVVESKADNTSKEDNTSKEDAKVEVVEFKDVPKGHWSEEAIHYLAKENIFKGYGNGQF
GFGDSITRGQVASLVQRYLKLENKVEQKERFTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQ
LKEDGNNKVNFKDVPTGHWAEGYVKALVDNNISKGDGKERFLGDDFVTREQYAQFLYNAITK

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI21389483, Length=210, Percent_Identity=29.5238095238095, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4506013, Length=225, Percent_Identity=28.8888888888889, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI21361633, Length=249, Percent_Identity=29.718875502008, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI55743114, Length=142, Percent_Identity=33.8028169014084, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI288541297, Length=283, Percent_Identity=28.6219081272085, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI288541295, Length=283, Percent_Identity=28.6219081272085, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI85986601, Length=249, Percent_Identity=27.3092369477912, Blast_Score=66, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17554124, Length=225, Percent_Identity=28.8888888888889, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17531555, Length=220, Percent_Identity=28.6363636363636, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17536161, Length=182, Percent_Identity=31.8681318681319, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71984630, Length=247, Percent_Identity=27.9352226720648, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17542472, Length=276, Percent_Identity=29.7101449275362, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322655, Length=227, Percent_Identity=29.9559471365639, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21358617, Length=211, Percent_Identity=27.4881516587678, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24658034, Length=182, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI221500776, Length=284, Percent_Identity=25.3521126760563, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 61009; Mature: 61009

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS01072 SLH_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLNTNEILDYSALKYMPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFSDVTPLVK
CCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHH
MDHLDSLDLSNNKITNVAPLIEMKNVKSLYLSGNQIEDVTALAKMEQLDYLNLANNKITN
HCCCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCC
VAPLSALKNVTYLTLAGNQIEDIKPLYSLPLTDLVLTRNKVKDLSGIEQMKQLEELWIGK
CHHHHHHCCCEEEEEECCCHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NEIKDVTPLSKMTQLKQLHLPNNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLV
HHHCCCCHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHH
FLSFVANEIRDVRPVIELSKTAYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLK
HHHHHHHHHHHHHHHHHHCCEEEEEEECCEEEEEECCCCCEEECEEEECCCCEEEEEEEE
GEGGTYSNDAVKWSTPGEKVYEFGVKDPFADTGIFFTGSVIQNVVESKADNTSKEDNTSK
ECCCCCCCCCEEECCCCHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCC
EDAKVEVVEFKDVPKGHWSEEAIHYLAKENIFKGYGNGQFGFGDSITRGQVASLVQRYLK
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LENKVEQKERFTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQ
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHH
LKEDGNNKVNFKDVPTGHWAEGYVKALVDNNISKGDGKERFLGDDFVTREQYAQFLYNAI
HHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TK
CC
>Mature Secondary Structure
MFLNTNEILDYSALKYMPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFSDVTPLVK
CCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHH
MDHLDSLDLSNNKITNVAPLIEMKNVKSLYLSGNQIEDVTALAKMEQLDYLNLANNKITN
HCCCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCC
VAPLSALKNVTYLTLAGNQIEDIKPLYSLPLTDLVLTRNKVKDLSGIEQMKQLEELWIGK
CHHHHHHCCCEEEEEECCCHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NEIKDVTPLSKMTQLKQLHLPNNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLV
HHHCCCCHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHH
FLSFVANEIRDVRPVIELSKTAYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLK
HHHHHHHHHHHHHHHHHHCCEEEEEEECCEEEEEECCCCCEEECEEEECCCCEEEEEEEE
GEGGTYSNDAVKWSTPGEKVYEFGVKDPFADTGIFFTGSVIQNVVESKADNTSKEDNTSK
ECCCCCCCCCEEECCCCHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCC
EDAKVEVVEFKDVPKGHWSEEAIHYLAKENIFKGYGNGQFGFGDSITRGQVASLVQRYLK
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LENKVEQKERFTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQ
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHH
LKEDGNNKVNFKDVPTGHWAEGYVKALVDNNISKGDGKERFLGDDFVTREQYAQFLYNAI
HHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]