Click here to switch to the map view.

The map label for this gene is phnW

Identifier: 49184257

GI number: 49184257

Start: 1283601

End: 1284698

Strand: Direct

Name: phnW

Synonym: BAS1240

Alternate gene names: 49184257

Gene position: 1283601-1284698 (Clockwise)

Preceding gene: 49184256

Following gene: 49184258

Centisome position: 24.55

GC content: 34.97

Gene sequence:

>1098_bases
ATGACTGAAAATCATTACTTATTATTAACGCCAGGACCATTAACGACAACAAAGACGGTAAAAGAAGTTATGTTATACGA
TTGGTGTACGTGGGATGTTGAATATAACACGATGGTACAAAAAGTAAGAGCTAAACTTGTATCGTTAGCAACGAAGGAAG
AAGAGAAATATACAACAGTATTAATGCAAGGAAGCGGTACGTTTTCAGTGGAAGCAGTAATCGGTTCTGTCATTCCAAAA
AACGGAAAGCTTCTTGTTTGTACAAATGGTGCATACGGTAAACGAATTGTACAAATGGCAGAGATGTTACATATAGATGT
GGTGGTCAGTCAAACAGAAGAGTGGGAGCCTACTAATATTGTAGAAGTAGAAAAGATATTACAACAAGATAAAGAGATTA
CACATATTGCAGTTGTTCATTGTGAAACAACAACAGGTATTATCAATCCAATTGTAGACGTATGTAAATTAGGGAAGCAA
TACGGAAAAGTAACACTAGTTGATGCAATGAGTAGTTTTGGTGGTATTGAAATAGATATTGCTGAGTTGCAAATTGACTT
TCTAATTAGTAGTGCGAATAAATGTATTCAAGGAGTTCCAGGGTTCGGATTTGTTATTGCACAGCGTGATGAATTATTGA
AATGTAAAGGGCAGGCACGTTCATTATCTTTAGATTTATACGATCAGTGGGAAACGATGGAAAATCAAAATGGGAAATGG
CGTTTTACGTCACCTACACATGTTGTACACGCTTTTTATCAAGCATTACTTGAATTAGAAAAAGAAGGCGGAGTAAGAGC
ACGTTACAATCGATATTACAACAATCAAAAACTATTAGTGAATAGAATGGGGGAAATTGGTTTTAAGCCACTCGTAAATG
AAAAATATCAATCTCCTATTATTACATCTTTTATTTATCCGGAAGGGAACTTCGAATTTCAACAGTTATATAATGAGTTA
AAACGCTACGGATTTGTTATTTATCCTGGGAAAATTTCGAAAGTAGATACGTTCCGCATTGGAAATATTGGTGATGTACA
TGAGGAAGACATAAATCGTTTAGTAGATAGTATTGCTAAAGGGGTTGTTATAGGTTGA

Upstream 100 bases:

>100_bases
TGGAGCGCACTTTACGATTGAAACGATGCAGGAACTTGAAAGTGTAATGGAACGTATCGAGAAACAAGAACTTATTATTT
CATAAAAGGGGCATGGGATC

Downstream 100 bases:

>100_bases
AAGTATTTTGCTTAGGTGGAGCAGGTAAAATTTGTCGTGAAGCAATTTTAGATTTAGTCCAATTTTCATCTTTTGAAACG
ATTACGGTAGCTGATTTTAA

Product: 2-aminoethylphosphonate--pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNTMVQKVRAKLVSLATKEEEKYTTVLMQGSGTFSVEAVIGSVIPK
NGKLLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNIVEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQ
YGKVTLVDAMSSFGGIEIDIAELQIDFLISSANKCIQGVPGFGFVIAQRDELLKCKGQARSLSLDLYDQWETMENQNGKW
RFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPLVNEKYQSPIITSFIYPEGNFEFQQLYNEL
KRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDSIAKGVVIG

Sequences:

>Translated_365_residues
MTENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNTMVQKVRAKLVSLATKEEEKYTTVLMQGSGTFSVEAVIGSVIPK
NGKLLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNIVEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQ
YGKVTLVDAMSSFGGIEIDIAELQIDFLISSANKCIQGVPGFGFVIAQRDELLKCKGQARSLSLDLYDQWETMENQNGKW
RFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPLVNEKYQSPIITSFIYPEGNFEFQQLYNEL
KRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDSIAKGVVIG
>Mature_364_residues
TENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNTMVQKVRAKLVSLATKEEEKYTTVLMQGSGTFSVEAVIGSVIPKN
GKLLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNIVEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQY
GKVTLVDAMSSFGGIEIDIAELQIDFLISSANKCIQGVPGFGFVIAQRDELLKCKGQARSLSLDLYDQWETMENQNGKWR
FTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPLVNEKYQSPIITSFIYPEGNFEFQQLYNELK
RYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDSIAKGVVIG

Specific function: Involved in phosphonate degradation

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily

Homologues:

Organism=Homo sapiens, GI4557289, Length=310, Percent_Identity=23.2258064516129, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17536281, Length=364, Percent_Identity=21.978021978022, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHNW_BACAA (C3P4E3)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002865840.1
- ProteinModelPortal:   C3P4E3
- SMR:   C3P4E3
- EnsemblBacteria:   EBBACT00000126830
- GeneID:   7850392
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_1408
- GeneTree:   EBGT00050000000896
- ProtClustDB:   PRK13479
- HAMAP:   MF_01376
- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR03301
- TIGRFAMs:   TIGR02326

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.37

Molecular weight: Translated: 41298; Mature: 41167

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNTMVQKVRAKLVSLATKEEEKYTTV
CCCCCEEEEECCCCCHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEE
LMQGSGTFSVEAVIGSVIPKNGKLLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNI
EEECCCCEEHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHEEEEECCCCCCCCCH
VEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQYGKVTLVDAMSSFGGIEIDI
HHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEEEE
AELQIDFLISSANKCIQGVPGFGFVIAQRDELLKCKGQARSLSLDLYDQWETMENQNGKW
EHEEEEHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCEEEEEHHHHHHHHCCCCCCE
RFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPLVNEKYQSPI
EECCHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCHHEEHHHHCCCCCCCCCHHHCCCE
ITSFIYPEGNFEFQQLYNELKRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDSIAK
EEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHC
GVVIG
CCCCC
>Mature Secondary Structure 
TENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNTMVQKVRAKLVSLATKEEEKYTTV
CCCCEEEEECCCCCHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEE
LMQGSGTFSVEAVIGSVIPKNGKLLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNI
EEECCCCEEHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHEEEEECCCCCCCCCH
VEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQYGKVTLVDAMSSFGGIEIDI
HHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEEEE
AELQIDFLISSANKCIQGVPGFGFVIAQRDELLKCKGQARSLSLDLYDQWETMENQNGKW
EHEEEEHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCEEEEEHHHHHHHHCCCCCCE
RFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPLVNEKYQSPI
EECCHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCHHEEHHHHCCCCCCCCCHHHCCCE
ITSFIYPEGNFEFQQLYNELKRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDSIAK
EEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHC
GVVIG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA