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The map label for this gene is resE [H]

Identifier: 49184232

GI number: 49184232

Start: 1260592

End: 1261992

Strand: Direct

Name: resE [H]

Synonym: BAS1214

Alternate gene names: 49184232

Gene position: 1260592-1261992 (Clockwise)

Preceding gene: 49184231

Following gene: 49184233

Centisome position: 24.11

GC content: 34.9

Gene sequence:

>1401_bases
ATGTTTACGATGGTACAGAAGCTTTGGTTGACAGTAGTATGTGCAGTATTTGTAACAGTTTCCTTTCTTTACTTTGTATC
TTTATATTCGTATGAAAAACTATATGTTGATAATTTAAAAGATTCATTAGTAATGGAAGGGAAGCGTCTTGCTGCGCAAT
ACGATAAGAGCGAAGGAATATCAACTTTTGAAGAGAAAGTAAGAGCGTTTGATCAAATATCTAGTTCAGATGTACTTTTC
GTGTCTAATCCACGTGATTTAAGTGCATGTTTACCATTTGATGTGCACCATCATTCTCTTATAAGTGAAGGGGATAGGCA
AGCTTTATTAGATGGAAAAACTGTGACAAAGATAGGGTATGAGGAACATTTTGAACGTAATATTATGGGGGTTGTCATTC
CTGTTTTAGAAAATAAAAAATTAGTTGGCATTGTATATTCTTATATTCCTTTAAAAAGTATAAAAGACTTAATATATGAT
ATGGGCCTTATTTTAGCACCGTTAGCACTTGCTATTACTTTACTGACAATATGGATTGGTAGAAAAATTATTATTGCTAT
TACGAGACCACTTTCGCAAATGGAACGAGTTGCCAATCATTTGGCTACGGGAGATTTCTCAGAACGAATTACAATTTCTT
CTGAAGATGAAATTGGACGATTAGGAAAAGCATTTAATAAAATGGCAAATTCTTTAGAGACAGAAGACGTAAAGCGTAAG
GAGTTTTTAGCTAACGTTTCGCATGAACTAAGAACACCACTTAGTTATATAAAAGGGTATAGCGAGGCTATTTTAGATGG
TGTAGCGAAGGGACCGCAGCAAGAAAAAGTGACACAGCTCATTCATAAAGAAGCAGATCGTATGCAACGTCTCGTTCATG
ATTTATTAGATTTAGCACAATTAGAAGGGGAACATTTTCCGTTACAGAAACAACCTATTGTTTTTTCACAACTAATTGAA
GATGTGCTAGATACGTATGAGATTAAGTTTATAGAAAAGAAAATTCGTATTTCAACAAATTTAAATCCAGAAATCATTGT
AATGATTGATGAGGATCGTATGCAACAAGTGCTTCATAACGTGTTAGATAATGCGATACGGTATACAAATCAAAACGGGG
ATATTATGATAACGCTCAGGCAGATAGATGATTACTGTGAATTGAGCATAAAAGATACAGGAATCGGTATTGATACGGAG
CATTTAGAAAACCTTGGCGAACGTTTTTACAGAGTCGATAAAGCGAGAAGTCGTCAACATGGTGGAACAGGTTTAGGCCT
GGCAATTGTAAGACAAATTGTTCATATACATGATGGACAGTGGCAAATTGAAAGCGAAAAAGGGAATGGAACGACGGTTA
GTATTAAATTGAAAGTACAGAATGAGGAGAGCATGTTCTAA

Upstream 100 bases:

>100_bases
AGTAGATACGCACGTGAAAACGATGCGTTTGAAGCTTGGAGAAGGTGGAAACTACATTCAAACTGTTTGGGGTGTAGGCT
ATAAATTTGAGGTGTAACGT

Downstream 100 bases:

>100_bases
TTTTTAGAGCATGCTCTTTATATTGAAGACAATAGTTATACGTAAAGATATAAATTAATATGTAATAAATATCGAAATTT
TGACGATTTTATGAACAAAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MFTMVQKLWLTVVCAVFVTVSFLYFVSLYSYEKLYVDNLKDSLVMEGKRLAAQYDKSEGISTFEEKVRAFDQISSSDVLF
VSNPRDLSACLPFDVHHHSLISEGDRQALLDGKTVTKIGYEEHFERNIMGVVIPVLENKKLVGIVYSYIPLKSIKDLIYD
MGLILAPLALAITLLTIWIGRKIIIAITRPLSQMERVANHLATGDFSERITISSEDEIGRLGKAFNKMANSLETEDVKRK
EFLANVSHELRTPLSYIKGYSEAILDGVAKGPQQEKVTQLIHKEADRMQRLVHDLLDLAQLEGEHFPLQKQPIVFSQLIE
DVLDTYEIKFIEKKIRISTNLNPEIIVMIDEDRMQQVLHNVLDNAIRYTNQNGDIMITLRQIDDYCELSIKDTGIGIDTE
HLENLGERFYRVDKARSRQHGGTGLGLAIVRQIVHIHDGQWQIESEKGNGTTVSIKLKVQNEESMF

Sequences:

>Translated_466_residues
MFTMVQKLWLTVVCAVFVTVSFLYFVSLYSYEKLYVDNLKDSLVMEGKRLAAQYDKSEGISTFEEKVRAFDQISSSDVLF
VSNPRDLSACLPFDVHHHSLISEGDRQALLDGKTVTKIGYEEHFERNIMGVVIPVLENKKLVGIVYSYIPLKSIKDLIYD
MGLILAPLALAITLLTIWIGRKIIIAITRPLSQMERVANHLATGDFSERITISSEDEIGRLGKAFNKMANSLETEDVKRK
EFLANVSHELRTPLSYIKGYSEAILDGVAKGPQQEKVTQLIHKEADRMQRLVHDLLDLAQLEGEHFPLQKQPIVFSQLIE
DVLDTYEIKFIEKKIRISTNLNPEIIVMIDEDRMQQVLHNVLDNAIRYTNQNGDIMITLRQIDDYCELSIKDTGIGIDTE
HLENLGERFYRVDKARSRQHGGTGLGLAIVRQIVHIHDGQWQIESEKGNGTTVSIKLKVQNEESMF
>Mature_466_residues
MFTMVQKLWLTVVCAVFVTVSFLYFVSLYSYEKLYVDNLKDSLVMEGKRLAAQYDKSEGISTFEEKVRAFDQISSSDVLF
VSNPRDLSACLPFDVHHHSLISEGDRQALLDGKTVTKIGYEEHFERNIMGVVIPVLENKKLVGIVYSYIPLKSIKDLIYD
MGLILAPLALAITLLTIWIGRKIIIAITRPLSQMERVANHLATGDFSERITISSEDEIGRLGKAFNKMANSLETEDVKRK
EFLANVSHELRTPLSYIKGYSEAILDGVAKGPQQEKVTQLIHKEADRMQRLVHDLLDLAQLEGEHFPLQKQPIVFSQLIE
DVLDTYEIKFIEKKIRISTNLNPEIIVMIDEDRMQQVLHNVLDNAIRYTNQNGDIMITLRQIDDYCELSIKDTGIGIDTE
HLENLGERFYRVDKARSRQHGGTGLGLAIVRQIVHIHDGQWQIESEKGNGTTVSIKLKVQNEESMF

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=35.1648351648352, Blast_Score=181, Evalue=8e-47,
Organism=Escherichia coli, GI1786600, Length=217, Percent_Identity=36.405529953917, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=27.5720164609054, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1789149, Length=360, Percent_Identity=25.8333333333333, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786783, Length=375, Percent_Identity=26.4, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=29.9145299145299, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=34.0425531914894, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790861, Length=345, Percent_Identity=26.6666666666667, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788713, Length=246, Percent_Identity=29.6747967479675, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790346, Length=273, Percent_Identity=27.1062271062271, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787894, Length=278, Percent_Identity=27.3381294964029, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI87081816, Length=338, Percent_Identity=25.7396449704142, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790551, Length=290, Percent_Identity=31.3793103448276, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786912, Length=273, Percent_Identity=26.7399267399267, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788279, Length=253, Percent_Identity=28.4584980237154, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1788549, Length=221, Percent_Identity=27.6018099547511, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082128, Length=289, Percent_Identity=22.8373702422145, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1789808, Length=293, Percent_Identity=27.9863481228669, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789403, Length=301, Percent_Identity=27.2425249169435, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787374, Length=431, Percent_Identity=21.8097447795824, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790300, Length=239, Percent_Identity=25.5230125523013, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53071; Mature: 53071

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTMVQKLWLTVVCAVFVTVSFLYFVSLYSYEKLYVDNLKDSLVMEGKRLAAQYDKSEGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
STFEEKVRAFDQISSSDVLFVSNPRDLSACLPFDVHHHSLISEGDRQALLDGKTVTKIGY
HHHHHHHHHHHCCCCCCEEEEECCCCCHHCCCCCCHHHHHHCCCCCHHHHCCCHHHHCCH
EEHFERNIMGVVIPVLENKKLVGIVYSYIPLKSIKDLIYDMGLILAPLALAITLLTIWIG
HHHHHCCCCEEEEEHHCCCEEEEHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RKIIIAITRPLSQMERVANHLATGDFSERITISSEDEIGRLGKAFNKMANSLETEDVKRK
CEEEEEECCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCHHHHHHH
EFLANVSHELRTPLSYIKGYSEAILDGVAKGPQQEKVTQLIHKEADRMQRLVHDLLDLAQ
HHHHHHHHHHHCHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEGEHFPLQKQPIVFSQLIEDVLDTYEIKFIEKKIRISTNLNPEIIVMIDEDRMQQVLHN
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECHHHHHHHHHH
VLDNAIRYTNQNGDIMITLRQIDDYCELSIKDTGIGIDTEHLENLGERFYRVDKARSRQH
HHHHHHHCCCCCCCEEEEEECCCCHHCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCC
GGTGLGLAIVRQIVHIHDGQWQIESEKGNGTTVSIKLKVQNEESMF
CCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure
MFTMVQKLWLTVVCAVFVTVSFLYFVSLYSYEKLYVDNLKDSLVMEGKRLAAQYDKSEGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
STFEEKVRAFDQISSSDVLFVSNPRDLSACLPFDVHHHSLISEGDRQALLDGKTVTKIGY
HHHHHHHHHHHCCCCCCEEEEECCCCCHHCCCCCCHHHHHHCCCCCHHHHCCCHHHHCCH
EEHFERNIMGVVIPVLENKKLVGIVYSYIPLKSIKDLIYDMGLILAPLALAITLLTIWIG
HHHHHCCCCEEEEEHHCCCEEEEHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RKIIIAITRPLSQMERVANHLATGDFSERITISSEDEIGRLGKAFNKMANSLETEDVKRK
CEEEEEECCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCHHHHHHH
EFLANVSHELRTPLSYIKGYSEAILDGVAKGPQQEKVTQLIHKEADRMQRLVHDLLDLAQ
HHHHHHHHHHHCHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEGEHFPLQKQPIVFSQLIEDVLDTYEIKFIEKKIRISTNLNPEIIVMIDEDRMQQVLHN
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECHHHHHHHHHH
VLDNAIRYTNQNGDIMITLRQIDDYCELSIKDTGIGIDTEHLENLGERFYRVDKARSRQH
HHHHHHHCCCCCCCEEEEEECCCCHHCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCC
GGTGLGLAIVRQIVHIHDGQWQIESEKGNGTTVSIKLKVQNEESMF
CCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]