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The map label for this gene is trpS

Identifier: 49184119

GI number: 49184119

Start: 1151313

End: 1152302

Strand: Reverse

Name: trpS

Synonym: BAS1099

Alternate gene names: 49184119

Gene position: 1152302-1151313 (Counterclockwise)

Preceding gene: 49184120

Following gene: 49184111

Centisome position: 22.04

GC content: 39.6

Gene sequence:

>990_bases
ATGTCAGTTATCTTTTCTGGTATTCAGCCGAGTGGAACGATTACACTTGGAAACTATTTAGGAGCTATGAAGCAATTTAC
AGAGCTACAGAACGAACACGACTGTTATTTCTGTATTGTAAACCAACATGCAATTACAGTACCTCAAGATCCGGTACAAC
TTCGTAAAAACATCCGCAGTCTTGCTGCACTTTATGTAGCATGCGGTATCGATCCTGAAAAAGCTACTTTATTTGTACAG
TCAGAAGTACCAGCACACGCTCAACTAGGATGGATTATGCAATCCGTTGCTTACGTTGGAGAATTAGAGCGTATGACGCA
ATATAAAGATAAAGCATCAGGTAGAGATTCAGTTCCAGCTGGATTACTAACTTACCCACCATTAATGGCTGCTGATATTT
TACTTTACAACACTGAGATCGTGCCTGTTGGTGATGACCAAAAGCAACATATGGAATTAACACGTGACCTAGCAGAGCGT
TTCAACAAACGCTTCCGTGAAGTATTCACAATTCCTGAAATCCGCATTCCAAAAGTAGGAGCTCGCGTTATGTCACTAAC
AGAGCCTACGAAAAAAATGAGTAAATCTGATCCGAATCCAAAATCAATGATCAGCATGCTTGACGAACCAAAAACAATTG
AAAAGAAAATTAAGAGTGCTGTAACTGATTCTGAAGGTATCGTGAAATTTGATAAAGAAAACAAACCTGGCATCTCTAAC
TTATTAACAATCTACTCTTCATTCTCTGGAAAAACAGTTGAAGAAATTGAAGCAATGTACGAAGGAAAAGGATACGGCGA
CTTTAAAGGCGATCTGGCACAAGTAGTCGTAGAAGCGATCCGCCCAATCCAAGACAAATATAACGAACTAATCAACTCAC
CAGAACTAGACGAAATTCTAGACAAAGGTGCCGAAAAAGCAAACCGCGTTGCATTCAAACAACTACGCAAAGTAGAAAAC
GCAATGGGGTTAAGTAGAAAACGTAGGTAA

Upstream 100 bases:

>100_bases
GTACCGCGGTCCATTCGTCCCTATAGTTTTTTGGGATGAATGGGCTTTTTTGTTTGCTTTCTCTTCCCTGTCACGCATTC
AATTTTAGGAGGAATTACTT

Downstream 100 bases:

>100_bases
CATATAAAGCGGAAGCGGCTTGCTTAGAATGTGAGGGGGATGGAGCTCCTGACGTAGAGGCGCTTTTTGCCTCGCAGGAA
GGCGCGAAGCCACCGAACAT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSVIFSGIQPSGTITLGNYLGAMKQFTELQNEHDCYFCIVNQHAITVPQDPVQLRKNIRSLAALYVACGIDPEKATLFVQ
SEVPAHAQLGWIMQSVAYVGELERMTQYKDKASGRDSVPAGLLTYPPLMAADILLYNTEIVPVGDDQKQHMELTRDLAER
FNKRFREVFTIPEIRIPKVGARVMSLTEPTKKMSKSDPNPKSMISMLDEPKTIEKKIKSAVTDSEGIVKFDKENKPGISN
LLTIYSSFSGKTVEEIEAMYEGKGYGDFKGDLAQVVVEAIRPIQDKYNELINSPELDEILDKGAEKANRVAFKQLRKVEN
AMGLSRKRR

Sequences:

>Translated_329_residues
MSVIFSGIQPSGTITLGNYLGAMKQFTELQNEHDCYFCIVNQHAITVPQDPVQLRKNIRSLAALYVACGIDPEKATLFVQ
SEVPAHAQLGWIMQSVAYVGELERMTQYKDKASGRDSVPAGLLTYPPLMAADILLYNTEIVPVGDDQKQHMELTRDLAER
FNKRFREVFTIPEIRIPKVGARVMSLTEPTKKMSKSDPNPKSMISMLDEPKTIEKKIKSAVTDSEGIVKFDKENKPGISN
LLTIYSSFSGKTVEEIEAMYEGKGYGDFKGDLAQVVVEAIRPIQDKYNELINSPELDEILDKGAEKANRVAFKQLRKVEN
AMGLSRKRR
>Mature_328_residues
SVIFSGIQPSGTITLGNYLGAMKQFTELQNEHDCYFCIVNQHAITVPQDPVQLRKNIRSLAALYVACGIDPEKATLFVQS
EVPAHAQLGWIMQSVAYVGELERMTQYKDKASGRDSVPAGLLTYPPLMAADILLYNTEIVPVGDDQKQHMELTRDLAERF
NKRFREVFTIPEIRIPKVGARVMSLTEPTKKMSKSDPNPKSMISMLDEPKTIEKKIKSAVTDSEGIVKFDKENKPGISNL
LTIYSSFSGKTVEEIEAMYEGKGYGDFKGDLAQVVVEAIRPIQDKYNELINSPELDEILDKGAEKANRVAFKQLRKVENA
MGLSRKRR

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI7710154, Length=324, Percent_Identity=41.0493827160494, Blast_Score=261, Evalue=4e-70,
Organism=Homo sapiens, GI41352700, Length=172, Percent_Identity=51.1627906976744, Blast_Score=186, Evalue=2e-47,
Organism=Escherichia coli, GI1789786, Length=329, Percent_Identity=52.887537993921, Blast_Score=363, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI71982800, Length=331, Percent_Identity=40.4833836858006, Blast_Score=248, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI71982793, Length=331, Percent_Identity=40.4833836858006, Blast_Score=247, Evalue=7e-66,
Organism=Saccharomyces cerevisiae, GI6320474, Length=345, Percent_Identity=40.2898550724638, Blast_Score=248, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24666151, Length=324, Percent_Identity=41.6666666666667, Blast_Score=264, Evalue=5e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYW_BACAN (Q81TS6)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_843665.1
- RefSeq:   YP_017801.1
- RefSeq:   YP_027371.1
- ProteinModelPortal:   Q81TS6
- SMR:   Q81TS6
- EnsemblBacteria:   EBBACT00000010158
- EnsemblBacteria:   EBBACT00000018380
- EnsemblBacteria:   EBBACT00000022162
- GeneID:   1089221
- GeneID:   2818802
- GeneID:   2848075
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_1188
- KEGG:   bar:GBAA_1188
- KEGG:   bat:BAS1099
- TIGR:   BA_1188
- TIGR:   GBAA_1188
- GeneTree:   EBGT00050000002240
- HOGENOM:   HBG293263
- OMA:   NKPGVSN
- ProtClustDB:   PRK00927
- BioCyc:   BANT260799:BAS1099-MONOMER
- BioCyc:   BANT261594:GBAA1188-MONOMER
- BRENDA:   6.1.1.2
- GO:   GO:0005737
- HAMAP:   MF_00140_B
- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10055
- PRINTS:   PR01039
- TIGRFAMs:   TIGR00233

Pfam domain/function: PF00579 tRNA-synt_1b

EC number: =6.1.1.2

Molecular weight: Translated: 36881; Mature: 36750

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 195-195

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIFSGIQPSGTITLGNYLGAMKQFTELQNEHDCYFCIVNQHAITVPQDPVQLRKNIRS
CCEEECCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCCHHHHHHHHHH
LAALYVACGIDPEKATLFVQSEVPAHAQLGWIMQSVAYVGELERMTQYKDKASGRDSVPA
HHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GLLTYPPLMAADILLYNTEIVPVGDDQKQHMELTRDLAERFNKRFREVFTIPEIRIPKVG
CHHHCCHHHHHHHHEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
ARVMSLTEPTKKMSKSDPNPKSMISMLDEPKTIEKKIKSAVTDSEGIVKFDKENKPGISN
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCCCCCCHHH
LLTIYSSFSGKTVEEIEAMYEGKGYGDFKGDLAQVVVEAIRPIQDKYNELINSPELDEIL
HHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
DKGAEKANRVAFKQLRKVENAMGLSRKRR
HHHHHHHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
SVIFSGIQPSGTITLGNYLGAMKQFTELQNEHDCYFCIVNQHAITVPQDPVQLRKNIRS
CEEECCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCCHHHHHHHHHH
LAALYVACGIDPEKATLFVQSEVPAHAQLGWIMQSVAYVGELERMTQYKDKASGRDSVPA
HHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GLLTYPPLMAADILLYNTEIVPVGDDQKQHMELTRDLAERFNKRFREVFTIPEIRIPKVG
CHHHCCHHHHHHHHEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
ARVMSLTEPTKKMSKSDPNPKSMISMLDEPKTIEKKIKSAVTDSEGIVKFDKENKPGISN
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCCCCCCHHH
LLTIYSSFSGKTVEEIEAMYEGKGYGDFKGDLAQVVVEAIRPIQDKYNELINSPELDEIL
HHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
DKGAEKANRVAFKQLRKVENAMGLSRKRR
HHHHHHHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629