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The map label for this gene is rocD

Identifier: 49184091

GI number: 49184091

Start: 1123438

End: 1124628

Strand: Reverse

Name: rocD

Synonym: BAS1071

Alternate gene names: 49184091

Gene position: 1124628-1123438 (Counterclockwise)

Preceding gene: 49184093

Following gene: 49184090

Centisome position: 21.51

GC content: 40.72

Gene sequence:

>1191_bases
ATGATTCAAACTAAGGATATCATCGAACTTACAGACACATACGGGGCAAATAACTATCACCCACTTCCAATCGTTATTTC
TAAAGCAGAAGGCGTTTGGGTAGAAGATCCTGAAGGAAACCGCTATATGGACTTATTAAGTGCATATTCGGCAGTAAACC
AAGGTCATCGTCACCCAAAAATTATTAACGCTTTAATTGACCAAGCTAATCGTGTTACGTTAACTTCTCGTGCTTTCCAT
AGCGATCAATTAGGTCCTTGGTACGAAAAAGTTGCGAAACTAACTAATAAAGAAATGGTACTTCCAATGAATACAGGTGC
AGAAGCTGTTGAAACTGCAATTAAAACAGCTCGCCGCTGGGCTTATGATGTGAAGAAAGTAGAAGCAAATCGTGCTGAGA
TTATCGTTTGTGAAGATAACTTCCACGGACGTACGATGGGTGCTGTTTCTATGTCTTCAAACGAAGAGTACAAGCGTGGA
TTCGGTCCAATGCTTCCTGGCATTATCGTAATTCCTTACGGTGATTTAGAAGCGTTAAAAGCTGCTATTACACCAAACAC
AGCTGCATTCATTTTAGAGCCAATCCAAGGTGAAGCAGGAATTAACATCCCACCAGCTGGTTTCTTAAAAGAAGCTCTTG
AAGTATGTAAAAAAGAAAACGTTTTATTCGTAGCAGATGAAATCCAAACTGGCTTAGGCCGTACTGGTAAAGTATTTGCT
TGTGATTGGGACAATGTAACTCCTGACATGTACATACTTGGTAAAGCACTTGGCGGCGGCGTATTCCCAATCTCTTGCGC
AGCAGCAAACCGCGACATTTTAGGCGTATTCGAGCCAGGTTCTCACGGTTCTACATTCGGTGGTAACCCACTTGCATGTG
CTGTTTCTATCGCAGCTCTTGAAGTGTTAGAAGAAGAAAAATTAACAGAGCGTTCTCTTCAATTAGGTGAAAAATTAGTT
GGGCAATTAAAAGAGATTGATAACCCAATGATCACTGAAGTTCGCGGTAAAGGTTTATTCATCGGTATCGAATTAAACGA
GCCAGCTCGTCCTTACTGTGAACAACTAAAAGCAGCTGGTCTATTATGTAAAGAAACACACGAAAATGTAATTCGTATCG
CACCACCACTAGTAATCTCTGAAGAAGATTTAGAGTGGGCGTTCCAAAAAATTAAAGCGGTATTATCGTAA

Upstream 100 bases:

>100_bases
GTTCATTTATTTTCAGGAAATGTTTCGCTTTTTTACATTTAAATGATATAATATTTAGAGTATTTACAAACTTCTTGTAA
TAACAAAAGGGGGAACAATC

Downstream 100 bases:

>100_bases
TAATAGAGAGTCTGTCCTACACGTTAGGACAGACTCTTTCTTTTTTTAGTAGTTTATCGTAAAATAAATTTTAATATTCT
GTCTTTTTTCGAAAGGGGTA

Product: ornithine--oxo-acid transaminase

Products: NA

Alternate protein names: OAT; Ornithine--oxo-acid aminotransferase

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MIQTKDIIELTDTYGANNYHPLPIVISKAEGVWVEDPEGNRYMDLLSAYSAVNQGHRHPKIINALIDQANRVTLTSRAFH
SDQLGPWYEKVAKLTNKEMVLPMNTGAEAVETAIKTARRWAYDVKKVEANRAEIIVCEDNFHGRTMGAVSMSSNEEYKRG
FGPMLPGIIVIPYGDLEALKAAITPNTAAFILEPIQGEAGINIPPAGFLKEALEVCKKENVLFVADEIQTGLGRTGKVFA
CDWDNVTPDMYILGKALGGGVFPISCAAANRDILGVFEPGSHGSTFGGNPLACAVSIAALEVLEEEKLTERSLQLGEKLV
GQLKEIDNPMITEVRGKGLFIGIELNEPARPYCEQLKAAGLLCKETHENVIRIAPPLVISEEDLEWAFQKIKAVLS

Sequences:

>Translated_396_residues
MIQTKDIIELTDTYGANNYHPLPIVISKAEGVWVEDPEGNRYMDLLSAYSAVNQGHRHPKIINALIDQANRVTLTSRAFH
SDQLGPWYEKVAKLTNKEMVLPMNTGAEAVETAIKTARRWAYDVKKVEANRAEIIVCEDNFHGRTMGAVSMSSNEEYKRG
FGPMLPGIIVIPYGDLEALKAAITPNTAAFILEPIQGEAGINIPPAGFLKEALEVCKKENVLFVADEIQTGLGRTGKVFA
CDWDNVTPDMYILGKALGGGVFPISCAAANRDILGVFEPGSHGSTFGGNPLACAVSIAALEVLEEEKLTERSLQLGEKLV
GQLKEIDNPMITEVRGKGLFIGIELNEPARPYCEQLKAAGLLCKETHENVIRIAPPLVISEEDLEWAFQKIKAVLS
>Mature_396_residues
MIQTKDIIELTDTYGANNYHPLPIVISKAEGVWVEDPEGNRYMDLLSAYSAVNQGHRHPKIINALIDQANRVTLTSRAFH
SDQLGPWYEKVAKLTNKEMVLPMNTGAEAVETAIKTARRWAYDVKKVEANRAEIIVCEDNFHGRTMGAVSMSSNEEYKRG
FGPMLPGIIVIPYGDLEALKAAITPNTAAFILEPIQGEAGINIPPAGFLKEALEVCKKENVLFVADEIQTGLGRTGKVFA
CDWDNVTPDMYILGKALGGGVFPISCAAANRDILGVFEPGSHGSTFGGNPLACAVSIAALEVLEEEKLTERSLQLGEKLV
GQLKEIDNPMITEVRGKGLFIGIELNEPARPYCEQLKAAGLLCKETHENVIRIAPPLVISEEDLEWAFQKIKAVLS

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily

Homologues:

Organism=Homo sapiens, GI4557809, Length=399, Percent_Identity=50.6265664160401, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=50, Blast_Score=291, Evalue=1e-78,
Organism=Homo sapiens, GI13994255, Length=435, Percent_Identity=28.9655172413793, Blast_Score=168, Evalue=6e-42,
Organism=Homo sapiens, GI24119277, Length=417, Percent_Identity=28.537170263789, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI37574042, Length=419, Percent_Identity=27.4463007159904, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI226442705, Length=419, Percent_Identity=26.7303102625298, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI226442709, Length=387, Percent_Identity=27.390180878553, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1789759, Length=379, Percent_Identity=36.6754617414248, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI145693181, Length=378, Percent_Identity=34.3915343915344, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI1788044, Length=381, Percent_Identity=34.1207349081365, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1787560, Length=407, Percent_Identity=31.9410319410319, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1789016, Length=406, Percent_Identity=30.0492610837438, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1786991, Length=362, Percent_Identity=31.767955801105, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786349, Length=356, Percent_Identity=28.6516853932584, Blast_Score=115, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI25144271, Length=389, Percent_Identity=49.8714652956298, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI25144274, Length=266, Percent_Identity=48.1203007518797, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI32564660, Length=431, Percent_Identity=32.4825986078886, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI71981843, Length=176, Percent_Identity=48.2954545454545, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI71992977, Length=430, Percent_Identity=27.6744186046512, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17541228, Length=426, Percent_Identity=24.1784037558685, Blast_Score=98, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6323470, Length=412, Percent_Identity=50.4854368932039, Blast_Score=395, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6324432, Length=382, Percent_Identity=31.9371727748691, Blast_Score=188, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6324386, Length=468, Percent_Identity=25.2136752136752, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=405, Percent_Identity=23.7037037037037, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357415, Length=389, Percent_Identity=51.9280205655527, Blast_Score=404, Evalue=1e-113,
Organism=Drosophila melanogaster, GI161085790, Length=427, Percent_Identity=29.5081967213115, Blast_Score=165, Evalue=5e-41,
Organism=Drosophila melanogaster, GI28574759, Length=422, Percent_Identity=29.8578199052133, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI21356575, Length=418, Percent_Identity=26.7942583732057, Blast_Score=147, Evalue=8e-36,
Organism=Drosophila melanogaster, GI281366494, Length=427, Percent_Identity=24.824355971897, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24667139, Length=427, Percent_Identity=24.824355971897, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24667143, Length=427, Percent_Identity=24.824355971897, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): OAT_BACAA (C3P3K3)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002865682.1
- ProteinModelPortal:   C3P3K3
- SMR:   C3P3K3
- EnsemblBacteria:   EBBACT00000125250
- GeneID:   7853315
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_1236
- GeneTree:   EBGT00070000031861
- ProtClustDB:   PRK04073
- GO:   GO:0005737
- HAMAP:   MF_01689
- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PANTHER:   PTHR11986
- PANTHER:   PTHR11986:SF18
- TIGRFAMs:   TIGR01885

Pfam domain/function: PF00202 Aminotran_3; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.13

Molecular weight: Translated: 43272; Mature: 43272

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQTKDIIELTDTYGANNYHPLPIVISKAEGVWVEDPEGNRYMDLLSAYSAVNQGHRHPK
CCCCCCHHHHHHCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHH
IINALIDQANRVTLTSRAFHSDQLGPWYEKVAKLTNKEMVLPMNTGAEAVETAIKTARRW
HHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHH
AYDVKKVEANRAEIIVCEDNFHGRTMGAVSMSSNEEYKRGFGPMLPGIIVIPYGDLEALK
HHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCHHHHCCCCCCCCEEEEECCCHHHHH
AAITPNTAAFILEPIQGEAGINIPPAGFLKEALEVCKKENVLFVADEIQTGLGRTGKVFA
HHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEHHHHHCCCCCCCEEE
CDWDNVTPDMYILGKALGGGVFPISCAAANRDILGVFEPGSHGSTFGGNPLACAVSIAAL
ECCCCCCCCCEEEEHHHCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
EVLEEEKLTERSLQLGEKLVGQLKEIDNPMITEVRGKGLFIGIELNEPARPYCEQLKAAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCHHHHHHHHCC
LLCKETHENVIRIAPPLVISEEDLEWAFQKIKAVLS
CHHHHHHCCEEEECCCEEECCCHHHHHHHHHHHHHC
>Mature Secondary Structure
MIQTKDIIELTDTYGANNYHPLPIVISKAEGVWVEDPEGNRYMDLLSAYSAVNQGHRHPK
CCCCCCHHHHHHCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHH
IINALIDQANRVTLTSRAFHSDQLGPWYEKVAKLTNKEMVLPMNTGAEAVETAIKTARRW
HHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHH
AYDVKKVEANRAEIIVCEDNFHGRTMGAVSMSSNEEYKRGFGPMLPGIIVIPYGDLEALK
HHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCHHHHCCCCCCCCEEEEECCCHHHHH
AAITPNTAAFILEPIQGEAGINIPPAGFLKEALEVCKKENVLFVADEIQTGLGRTGKVFA
HHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEHHHHHCCCCCCCEEE
CDWDNVTPDMYILGKALGGGVFPISCAAANRDILGVFEPGSHGSTFGGNPLACAVSIAAL
ECCCCCCCCCEEEEHHHCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
EVLEEEKLTERSLQLGEKLVGQLKEIDNPMITEVRGKGLFIGIELNEPARPYCEQLKAAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCHHHHHHHHCC
LLCKETHENVIRIAPPLVISEEDLEWAFQKIKAVLS
CHHHHHHCCEEEECCCEEECCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA