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The map label for this gene is rsbP [H]

Identifier: 49183952

GI number: 49183952

Start: 987442

End: 988584

Strand: Direct

Name: rsbP [H]

Synonym: BAS0930

Alternate gene names: 49183952

Gene position: 987442-988584 (Clockwise)

Preceding gene: 49183951

Following gene: 49183956

Centisome position: 18.89

GC content: 32.9

Gene sequence:

>1143_bases
GTGTCCATTTTAATTGTAGATGATAATCCGGTTAACATTTTTGTAATTAAGAAGATTTTAAAACAAGCCGGATATCAGGA
TCTTGTATCGCTGAATTCTGCACAAGAGCTTTTCGAATACATCCATTTTGGAAAAGATTCTTCCAGGCATAACGAAATAG
ATTTAATACTATTAGATATTATGATGCCTGAAATTGATGGACTTGAAGTTTGTAGGCGATTACAAAAAGAGGAGAAGTTT
AAAGATATTCCTATCATTTTTGTAACAGCTTTAGAAGATGCGAATAAATTAGCTGAAGCGCTTGATATAGGGGCAATGGA
TTATATTACGAAACCTATAAATAAAGTTGAATTGTTAGCGCGTATGCGTGTAGCATTATGCTTGAAATCGGAATTAAATT
GGCATAAAGAACAGGAAGAGAATCTTCGGAATGAACTAGATTTAGCTACGCAAGTACAAAGAAACTTATTAAGTAGCCCA
TTAAGAGAAGAGCATATAAAAATTGAAGCAAGTTACTTACCTTCATTTAAACTAGCTGGAGATATGTACTACTGGTATAA
AATCGATGAAAACCGCTACGGTATTATATTATTAGATGTGATGGGACATGGTGTATCTGCTTCCTTAGTTTGCATGTTCA
TTTCGTCTGTATTACGTGAAACGATTAAATGTTTAATCGATCCAGAACTTGTCATGAAAGATTTAAATAAATATATGACT
CTTTTACATAATGAGAATGACAACATTCCATATTATTTTACAGCGATATACTTAGTAGTTAATACAGAAGATAGAACGAT
TGAATATGTAAATGCAGGACATCCTTCTGGATATGTTTTAGTTGATGAAACAAATGTAGTTGAACTAAATCGCGGGAGTT
GTGCGGTAGGTTTTTTTGATGAAATAAAAGTTGAAAAGACAGTTATACCTTTTGAGAAAAATGCTCAAATCGTATTGTTT
ACAGATGGTGTTCTTGAAGCAATTGCAAATGATGAATTTGAGGCTGAAGAGAAATTACGTACTTTTACAGAAAGAAAATG
GGGAGAGCTAGAAGAAGAGATAGAAGGGTTTTACAAGGAAGAACAGAAACAAGCGCAATCAGATGATATGTGTCTCATTA
TGATACAAACGAATGCGAAATAA

Upstream 100 bases:

>100_bases
ATGAGTAGGAAATTTTCATTTTATAACTGAGTATGTAATACTAGAAAAATAGAAAATGATAACAGATTTACATTTTAAAT
AAGAAAAGGGGAAATAACTT

Downstream 100 bases:

>100_bases
AAAGCGTATGAAATCCAAATAGAGGATTTCATACGCTTTTATTGTATTTTTTGATAGATTTGTTCGTGTGGATTAAATTG
CGTATAATGCGGCATGATAT

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSILIVDDNPVNIFVIKKILKQAGYQDLVSLNSAQELFEYIHFGKDSSRHNEIDLILLDIMMPEIDGLEVCRRLQKEEKF
KDIPIIFVTALEDANKLAEALDIGAMDYITKPINKVELLARMRVALCLKSELNWHKEQEENLRNELDLATQVQRNLLSSP
LREEHIKIEASYLPSFKLAGDMYYWYKIDENRYGIILLDVMGHGVSASLVCMFISSVLRETIKCLIDPELVMKDLNKYMT
LLHNENDNIPYYFTAIYLVVNTEDRTIEYVNAGHPSGYVLVDETNVVELNRGSCAVGFFDEIKVEKTVIPFEKNAQIVLF
TDGVLEAIANDEFEAEEKLRTFTERKWGELEEEIEGFYKEEQKQAQSDDMCLIMIQTNAK

Sequences:

>Translated_380_residues
MSILIVDDNPVNIFVIKKILKQAGYQDLVSLNSAQELFEYIHFGKDSSRHNEIDLILLDIMMPEIDGLEVCRRLQKEEKF
KDIPIIFVTALEDANKLAEALDIGAMDYITKPINKVELLARMRVALCLKSELNWHKEQEENLRNELDLATQVQRNLLSSP
LREEHIKIEASYLPSFKLAGDMYYWYKIDENRYGIILLDVMGHGVSASLVCMFISSVLRETIKCLIDPELVMKDLNKYMT
LLHNENDNIPYYFTAIYLVVNTEDRTIEYVNAGHPSGYVLVDETNVVELNRGSCAVGFFDEIKVEKTVIPFEKNAQIVLF
TDGVLEAIANDEFEAEEKLRTFTERKWGELEEEIEGFYKEEQKQAQSDDMCLIMIQTNAK
>Mature_379_residues
SILIVDDNPVNIFVIKKILKQAGYQDLVSLNSAQELFEYIHFGKDSSRHNEIDLILLDIMMPEIDGLEVCRRLQKEEKFK
DIPIIFVTALEDANKLAEALDIGAMDYITKPINKVELLARMRVALCLKSELNWHKEQEENLRNELDLATQVQRNLLSSPL
REEHIKIEASYLPSFKLAGDMYYWYKIDENRYGIILLDVMGHGVSASLVCMFISSVLRETIKCLIDPELVMKDLNKYMTL
LHNENDNIPYYFTAIYLVVNTEDRTIEYVNAGHPSGYVLVDETNVVELNRGSCAVGFFDEIKVEKTVIPFEKNAQIVLFT
DGVLEAIANDEFEAEEKLRTFTERKWGELEEEIEGFYKEEQKQAQSDDMCLIMIQTNAK

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to energy stress [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=125, Percent_Identity=37.6, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789809, Length=139, Percent_Identity=35.9712230215827, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789149, Length=113, Percent_Identity=33.6283185840708, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082012, Length=136, Percent_Identity=32.3529411764706, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786784, Length=126, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786599, Length=73, Percent_Identity=39.7260273972603, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=116, Percent_Identity=30.1724137931034, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR001932
- InterPro:   IPR010822 [H]

Pfam domain/function: PF00989 PAS; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 43830; Mature: 43699

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILIVDDNPVNIFVIKKILKQAGYQDLVSLNSAQELFEYIHFGKDSSRHNEIDLILLDI
CEEEEECCCCCCHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEEEEEE
MMPEIDGLEVCRRLQKEEKFKDIPIIFVTALEDANKLAEALDIGAMDYITKPINKVELLA
CCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCHHHHHHCCHHHHHHHH
RMRVALCLKSELNWHKEQEENLRNELDLATQVQRNLLSSPLREEHIKIEASYLPSFKLAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCEEEEC
DMYYWYKIDENRYGIILLDVMGHGVSASLVCMFISSVLRETIKCLIDPELVMKDLNKYMT
CEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LLHNENDNIPYYFTAIYLVVNTEDRTIEYVNAGHPSGYVLVDETNVVELNRGSCAVGFFD
HHCCCCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCEEEEECCCEEEECCCCEEEECHH
EIKVEKTVIPFEKNAQIVLFTDGVLEAIANDEFEAEEKLRTFTERKWGELEEEIEGFYKE
HHEEEEEEECCCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
EQKQAQSDDMCLIMIQTNAK
HHHHCCCCCEEEEEEECCCC
>Mature Secondary Structure 
SILIVDDNPVNIFVIKKILKQAGYQDLVSLNSAQELFEYIHFGKDSSRHNEIDLILLDI
EEEEECCCCCCHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEEEEEE
MMPEIDGLEVCRRLQKEEKFKDIPIIFVTALEDANKLAEALDIGAMDYITKPINKVELLA
CCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCHHHHHHCCHHHHHHHH
RMRVALCLKSELNWHKEQEENLRNELDLATQVQRNLLSSPLREEHIKIEASYLPSFKLAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCEEEEC
DMYYWYKIDENRYGIILLDVMGHGVSASLVCMFISSVLRETIKCLIDPELVMKDLNKYMT
CEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LLHNENDNIPYYFTAIYLVVNTEDRTIEYVNAGHPSGYVLVDETNVVELNRGSCAVGFFD
HHCCCCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCEEEEECCCEEEECCCCEEEECHH
EIKVEKTVIPFEKNAQIVLFTDGVLEAIANDEFEAEEKLRTFTERKWGELEEEIEGFYKE
HHEEEEEEECCCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
EQKQAQSDDMCLIMIQTNAK
HHHHCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 10632888 [H]