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The map label for this gene is dhaK [H]

Identifier: 49183930

GI number: 49183930

Start: 968122

End: 969873

Strand: Direct

Name: dhaK [H]

Synonym: BAS0907

Alternate gene names: 49183930

Gene position: 968122-969873 (Clockwise)

Preceding gene: 49183927

Following gene: 49183932

Centisome position: 18.52

GC content: 41.61

Gene sequence:

>1752_bases
ATGAAAAAGATTATAAACAAACCAGAAACATTAGTAATGGAAATGTGCAACGGAATGGTTATGGCTCACCCAGAGCTTGA
GCTTTTGAAAAAATATAAAGTCATTAAGAAGAAAGAAATGAATGAAAATAAAGTAACGTTAATTAGTGGCGGTGGTAGTG
GTCATGAGCCGGCACATGCAGGACTAGTCGGAAAAGGAATGCTAGATGCGGCAGTGTGCGGAGATGTGTTTGCTTCGCCT
TCACAAATTCAGGTATATCAAGCAATTAAAGAGACAGCTAGTAAAAAAGGTACGTTATTAATTATTAAAAATTATAGCGG
CGATATTATGAATTTCAAAAACGGAGCTCATTTAGCGACGGAAGATGGAATTGAAGTCGACTACGTAAAAGTGGACGATG
ATATTGCGGTAGAAGATAGTCTATACACAGTAGGACGCCGCGGCGTTGCGGGCGTTATTTTAGTCCATAAAATTGCCGGT
GCAGCAGCGGAAGCAGGTATGGATTTAAGAGCGGTGAAAGCTATAGCGGAAAAAGCAGCCGCTAACGTGCGCACAATTGG
TTTAGCGTTAACGTCTTGTACAGTTCCAGCGAGCGGATCACCTACTTTCACACTTGCGGAAGATGAAATGGAATACGGCG
TAGGTATTCACGGTGAACCGGGAATTAAGCGTGAAAAAATGTTGTCAGCTGATGAATTAGCGAACCGTATGACAAATGAT
TTAATGAAAGATTTAGGAGTAAAAGATGGCGAGGAAATCGCACTGCTAGTTAACGGTTTTGGCGGAACACCACTACAAGA
ACTTTACTTATTTAACAACGCAGTTACGAGAGAATTAGCTGCTAGAAACATTAAAATCAATAGAGTATTCGTCGGCAATT
ATATGACGAGTATCGATATGGCTGGTATGTCTTTAACAGTGATGAAATTAGATGATGAGTTAAAAACATTATTATCGAAA
GAGTGTAATACACCAGCGTTTAAAGTAGATGGGCCAGTTGAAAGTGTAGAGTACGTAAATGTGCTTGAAGAGACAGAAGA
GAAGGAAGTTTCATTTGAACTAGAAACAGCGGAAGAGCACGCAGTTATTAAAAATAATGTCATCACATTAAACAACATGA
TCTATCTCGTTGATAAAATGAGCGATATTATTATTAAAAATGAAGTACCGTTCTGTGAGTTAGATACACATGCAGGTGAC
GGTGACTTCGGAATGAGTGTGGCAAAAGGATTTAAGCAATTAAAACGTGAGTGGCATTCTATCGTGGAGCAAGAAAACGT
AACAATCGGATCATTCCTTGACGGTTGTTCCATGATTATTATGGAACATTGCGGCGGCGCATCTGGTCCAATTTGGGGCG
GTGCATTCCGCGCAGCTAGTAAAGCAGCAGGCGAAAAACGTGAGTTAACAGTGAAAGAATTCGCTGAAATGTTGCAAGGA
GCACTGCAAGGTATACAATCTATCGGTGAAAGATCGTTCGGCAGAGGAGCAGTAGTTGGTGACAAAACACTAGTTGACGC
ACTTGCTCCATGTGTAGACTCTTGGTTAGCTAGCGCTTCAAACGAAGAAGACATGAAAACTGCCTTTGAAAAAGGAGCAG
AAGCAGCGGTTAAAGGAGCAGAGTACACGAAAGAAATCGTAGCTCGCATGGGCCGCGCCGGTACAGTTGGTGAAAGAAGT
TTAGGATATCCTGATGCAGGTGCGCATGCGCTTGGGGTTATCTTTACGGAGATTGCGGGTAGTTTGAAATAG

Upstream 100 bases:

>100_bases
TTTGTCCGTTTACTATAAAACGCTTTCATTTTAACATGAGTAGTAAAAAGAAGATTTCAAATATATCACAATATATTAAA
GGAATTGAGGGAGAATCACA

Downstream 100 bases:

>100_bases
GAATTGGAAAGTCCCCTCTGCCTTAAGGTGGAGGGGATCTTTATTTATAACCATCATTCTTCCAGTGAAAAAATATATTT
GTTAGCCAATCTAGAAGCAG

Product: dihydroxyacetone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHAGLVGKGMLDAAVCGDVFASP
SQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLATEDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAG
AAAEAGMDLRAVKAIAEKAAANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADELANRMTND
LMKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDMAGMSLTVMKLDDELKTLLSK
ECNTPAFKVDGPVESVEYVNVLEETEEKEVSFELETAEEHAVIKNNVITLNNMIYLVDKMSDIIIKNEVPFCELDTHAGD
GDFGMSVAKGFKQLKREWHSIVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEMLQG
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLASASNEEDMKTAFEKGAEAAVKGAEYTKEIVARMGRAGTVGERS
LGYPDAGAHALGVIFTEIAGSLK

Sequences:

>Translated_583_residues
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHAGLVGKGMLDAAVCGDVFASP
SQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLATEDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAG
AAAEAGMDLRAVKAIAEKAAANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADELANRMTND
LMKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDMAGMSLTVMKLDDELKTLLSK
ECNTPAFKVDGPVESVEYVNVLEETEEKEVSFELETAEEHAVIKNNVITLNNMIYLVDKMSDIIIKNEVPFCELDTHAGD
GDFGMSVAKGFKQLKREWHSIVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEMLQG
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLASASNEEDMKTAFEKGAEAAVKGAEYTKEIVARMGRAGTVGERS
LGYPDAGAHALGVIFTEIAGSLK
>Mature_583_residues
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHAGLVGKGMLDAAVCGDVFASP
SQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLATEDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAG
AAAEAGMDLRAVKAIAEKAAANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADELANRMTND
LMKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDMAGMSLTVMKLDDELKTLLSK
ECNTPAFKVDGPVESVEYVNVLEETEEKEVSFELETAEEHAVIKNNVITLNNMIYLVDKMSDIIIKNEVPFCELDTHAGD
GDFGMSVAKGFKQLKREWHSIVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEMLQG
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLASASNEEDMKTAFEKGAEAAVKGAEYTKEIVARMGRAGTVGERS
LGYPDAGAHALGVIFTEIAGSLK

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=576, Percent_Identity=32.8125, Blast_Score=282, Evalue=5e-76,
Organism=Escherichia coli, GI87081857, Length=353, Percent_Identity=40.7932011331445, Blast_Score=277, Evalue=1e-75,
Organism=Escherichia coli, GI1787449, Length=212, Percent_Identity=28.7735849056604, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17565018, Length=581, Percent_Identity=31.3253012048193, Blast_Score=269, Evalue=3e-72,
Organism=Saccharomyces cerevisiae, GI6321055, Length=601, Percent_Identity=31.7803660565724, Blast_Score=225, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6323570, Length=589, Percent_Identity=31.918505942275, Blast_Score=209, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 62575; Mature: 62575

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHA
CCCCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
GLVGKGMLDAAVCGDVFASPSQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLAT
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCEEC
EDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAGAAAEAGMDLRAVKAIAEKAA
CCCCEEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADELANRMTND
CCHHEEEEEEEEEECCCCCCCCEEEECCCHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHH
LMKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDM
HHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHH
AGMSLTVMKLDDELKTLLSKECNTPAFKVDGPVESVEYVNVLEETEEKEVSFELETAEEH
CCCEEEEEECCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCHHHEEEEEECCCCC
AVIKNNVITLNNMIYLVDKMSDIIIKNEVPFCELDTHAGDGDFGMSVAKGFKQLKREWHS
HHHHCCEEEECCEEEEEEHHHHEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
IVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEMLQG
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLASASNEEDMKTAFEKGAEAAVKGA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHH
EYTKEIVARMGRAGTVGERSLGYPDAGAHALGVIFTEIAGSLK
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHA
CCCCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
GLVGKGMLDAAVCGDVFASPSQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLAT
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCEEC
EDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAGAAAEAGMDLRAVKAIAEKAA
CCCCEEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADELANRMTND
CCHHEEEEEEEEEECCCCCCCCEEEECCCHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHH
LMKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDM
HHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHH
AGMSLTVMKLDDELKTLLSKECNTPAFKVDGPVESVEYVNVLEETEEKEVSFELETAEEH
CCCEEEEEECCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCHHHEEEEEECCCCC
AVIKNNVITLNNMIYLVDKMSDIIIKNEVPFCELDTHAGDGDFGMSVAKGFKQLKREWHS
HHHHCCEEEECCEEEEEEHHHHEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
IVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEMLQG
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLASASNEEDMKTAFEKGAEAAVKGA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHH
EYTKEIVARMGRAGTVGERSLGYPDAGAHALGVIFTEIAGSLK
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]