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The map label for this gene is dnaC [H]

Identifier: 49183904

GI number: 49183904

Start: 945457

End: 946752

Strand: Direct

Name: dnaC [H]

Synonym: BAS0880

Alternate gene names: 49183904

Gene position: 945457-946752 (Clockwise)

Preceding gene: 49183903

Following gene: 49183905

Centisome position: 18.08

GC content: 43.9

Gene sequence:

>1296_bases
GTGGCGTCCATGAGTATTCAAAATGTGGAGGCGGAAAAGACGGTGTTAGGTTCTCTACTACTTGATGGAGAGCTTATTAA
GGAGTGCCGTTTGACGGAGCAGTATTTTTCGATGCCGGTGCATAAGTCTATATTTCAGTTAATGAGAAAGATGGAAGGAG
AGGGGCAACCGATTGATCTTGTGACTTTTACTTCTAGGGTAGATCCGAATTTTTTGAAGGGGATCGGGGGAATGGAGTAT
TTTATAGGATTAATGGATGGTGTGCCCACTACTAGCAACTTCTCATATTATGAGGGGCTTGTTCGAGGTGCTTGGAAAAT
GTATCAGGCTGGCGTCCTTGGGCACAAGATGGGAGAGCGTCTTATTGCGGAGAAGAGTGAGAAGATTATTGGTGAGACGA
TTACGGCACTTTGTGAGTTAGAGGAGAAAGACTGTGTATGTGAGTTTGATTTGAAGGATGCGCTAGTTGATTTATATGAA
GAGCTTCATCAAGATGCGAAAGAGATTACTGGTATTGAGACGGGTTATACATCGCTAAATAAAATGACGTGCGGATTGCA
GGAAGGAGATTTTGTCGTTCTTGGTGCGCGTCCTTCTATGGGGAAGACTGCGTTTGCGCTAAATGTGGGACTGCATGCGG
CGAAGTCTGGAGCGGCGGTGGGATTGTTTTCGTTAGAGATGAGTAGTAAGCAATTGTTAAAAAGGATGGCTTCTTGCGTA
GGTGAGGTATCAGGGGGCAGACTGAAAAATCCGAAGCACCGTTTTGCGATAGAAGACTGGGAAAGGGTGAGTAAGGCGTT
TGCGGAGATTGGTGAGTTACCCCTTGAGATTTACGATCATGCAGGTGTTACGGTGCAAGATATTTGGATGCAAACTCGTA
AGTTAAAGAGGAAGCATGGTGACAAAAAGATTTTAATTATTGTAGATTACTTGCAGCTTATTACGGGTGATCCGAAGCAT
AAGGGAAATCGATTTCAAGAGATTAGTGAGATTTCTCGTAAGCTTAAGTTATTAGCACGTGAATTAAATGTTTGCGTAGT
AGCATTATCGCAATTGTCTCGTTCTGTAGAGTCACGGCAAGATAAGCGTCCTCTTTTATCTGATTTAAGAGAGACCGGAC
AAATTGAGCAAGATGCGGATGTCATTATGCTTATGTATCGCGAAGATTATTACGATAAAGAAACGATGCAGAAAGAGATG
ACGGAGATTCATGTGGCGAAGCATCGGAATGGGCCTGTGGGGAGTTTTAAGCTGCGGTTTATGAAGGAGTTTGGTCGGTT
TGTGGAGGGGGGATGA

Upstream 100 bases:

>100_bases
CTAGTACGGGGGAGACGGAGGAGTTTTTGGCGAGGTGTGAGGAGTGGGAGAAGAATGCGCCATCTGAGGAAGAGTTGCAG
CGCTTTTTAGCGGAGCGCGG

Downstream 100 bases:

>100_bases
TAAAATAGAAAAAGGTAAAGGAGTGGTTAAGGATGACAAAAGTGGGCCGTTTATATGAACAGGAGAAGCAAGAAGAAATT
GATAAAGCACTTTCGGCAGC

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MASMSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEGEGQPIDLVTFTSRVDPNFLKGIGGMEY
FIGLMDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKIIGETITALCELEEKDCVCEFDLKDALVDLYE
ELHQDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRMASCV
GEVSGGRLKNPKHRFAIEDWERVSKAFAEIGELPLEIYDHAGVTVQDIWMQTRKLKRKHGDKKILIIVDYLQLITGDPKH
KGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETMQKEM
TEIHVAKHRNGPVGSFKLRFMKEFGRFVEGG

Sequences:

>Translated_431_residues
MASMSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEGEGQPIDLVTFTSRVDPNFLKGIGGMEY
FIGLMDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKIIGETITALCELEEKDCVCEFDLKDALVDLYE
ELHQDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRMASCV
GEVSGGRLKNPKHRFAIEDWERVSKAFAEIGELPLEIYDHAGVTVQDIWMQTRKLKRKHGDKKILIIVDYLQLITGDPKH
KGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETMQKEM
TEIHVAKHRNGPVGSFKLRFMKEFGRFVEGG
>Mature_430_residues
ASMSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEGEGQPIDLVTFTSRVDPNFLKGIGGMEYF
IGLMDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKIIGETITALCELEEKDCVCEFDLKDALVDLYEE
LHQDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRMASCVG
EVSGGRLKNPKHRFAIEDWERVSKAFAEIGELPLEIYDHAGVTVQDIWMQTRKLKRKHGDKKILIIVDYLQLITGDPKHK
GNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETMQKEMT
EIHVAKHRNGPVGSFKLRFMKEFGRFVEGG

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=442, Percent_Identity=38.0090497737557, Blast_Score=267, Evalue=9e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 48573; Mature: 48442

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASMSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEGEGQPIDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEE
VTFTSRVDPNFLKGIGGMEYFIGLMDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGER
EEECCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAEKSEKIIGETITALCELEEKDCVCEFDLKDALVDLYEELHQDAKEITGIETGYTSLN
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRMASCV
HHCCCCCCCCEEEEECCCCCCCEEEEEECCHHHCCCCCEEEEEEECCCHHHHHHHHHHHH
GEVSGGRLKNPKHRFAIEDWERVSKAFAEIGELPLEIYDHAGVTVQDIWMQTRKLKRKHG
HHCCCCCCCCCCHHCCHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHCC
DKKILIIVDYLQLITGDPKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQ
CCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETMQKEMTEIHVAKHRNGPVGSFKLRF
CCCHHHHHHHHCCCCCCCCCEEEEEEHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
MKEFGRFVEGG
HHHHHHHHCCC
>Mature Secondary Structure 
ASMSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEGEGQPIDL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEE
VTFTSRVDPNFLKGIGGMEYFIGLMDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGER
EEECCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAEKSEKIIGETITALCELEEKDCVCEFDLKDALVDLYEELHQDAKEITGIETGYTSLN
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRMASCV
HHCCCCCCCCEEEEECCCCCCCEEEEEECCHHHCCCCCEEEEEEECCCHHHHHHHHHHHH
GEVSGGRLKNPKHRFAIEDWERVSKAFAEIGELPLEIYDHAGVTVQDIWMQTRKLKRKHG
HHCCCCCCCCCCHHCCHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHCC
DKKILIIVDYLQLITGDPKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQ
CCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETMQKEMTEIHVAKHRNGPVGSFKLRF
CCCHHHHHHHHCCCCCCCCCEEEEEEHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
MKEFGRFVEGG
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]