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The map label for this gene is citT [H]

Identifier: 49183894

GI number: 49183894

Start: 934209

End: 934886

Strand: Direct

Name: citT [H]

Synonym: BAS0870

Alternate gene names: 49183894

Gene position: 934209-934886 (Clockwise)

Preceding gene: 49183893

Following gene: 49183895

Centisome position: 17.87

GC content: 36.58

Gene sequence:

>678_bases
ATGTTGAAGGTTGCAATTGCAGAAGATGATTTCCGCGTCGCGCAAATTCAGGAAGAGTTTTTATTAAAAATTAAGGATGT
AAAAGTGATGGGAAAAGCGTTGAACGCAAAAGAAACAATGGAACTACTACAAAGGGAAGAAATCGATTTGCTTCTATTAG
ATAACTATTTACCAGATGGAATTGGAACCGACTTATTACCACAAATTCATGCTGAATTTCCAAATGTTGACGTCATTATG
GTGACAGCGGCAAATGAAAACCATATGTTAGAAAAAGCAATTCGAAACGGCGTAAGTAACTACCTTATAAAACCGGTCAC
GTTAGAAAAATTTGTTCGCACAATTGAAGACTATAAAAGAAAGAAGCAACTATTACATAATAACAATGAAGTGAATCAAA
CACTCATAGATAATTTCTTCGGCATTTCGCAAACACAAGACATAAAAAACTTACCGACAGGTGTGGATCCGTTAACACTG
CAAAAAGTGAAAGGAATTATAAAAGGATTTGAAGAGGGCATTACAATAGAAGAAATGGGAGAACAAATGGGTGCTTCCAG
AACAACCGCAAGAAGATATTTAGAATATTTAGTAGCGACAAACGAATGTACAGTAGAGTACACATACGGCATTATCGGAC
GACCAGAACGAAAGTACCGAATAGGACGAGGGCTATGA

Upstream 100 bases:

>100_bases
AACGATTGAAATTCAAAACGAGAGAAATGGGGGAGCTATTTTTACAATTTACCTTCCGAAAACATTGAGAGAAAGTACAT
AACAAACAGGGGATGGGTAT

Downstream 100 bases:

>100_bases
AAAAACGATTATTACTATGTATATGGATCATGACAGGAGTAATAGCTGGTTGTTCTTCGGAAAAATCCCAAACGAATATA
GTAAACATAGACGAAGTAGA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MLKVAIAEDDFRVAQIQEEFLLKIKDVKVMGKALNAKETMELLQREEIDLLLLDNYLPDGIGTDLLPQIHAEFPNVDVIM
VTAANENHMLEKAIRNGVSNYLIKPVTLEKFVRTIEDYKRKKQLLHNNNEVNQTLIDNFFGISQTQDIKNLPTGVDPLTL
QKVKGIIKGFEEGITIEEMGEQMGASRTTARRYLEYLVATNECTVEYTYGIIGRPERKYRIGRGL

Sequences:

>Translated_225_residues
MLKVAIAEDDFRVAQIQEEFLLKIKDVKVMGKALNAKETMELLQREEIDLLLLDNYLPDGIGTDLLPQIHAEFPNVDVIM
VTAANENHMLEKAIRNGVSNYLIKPVTLEKFVRTIEDYKRKKQLLHNNNEVNQTLIDNFFGISQTQDIKNLPTGVDPLTL
QKVKGIIKGFEEGITIEEMGEQMGASRTTARRYLEYLVATNECTVEYTYGIIGRPERKYRIGRGL
>Mature_225_residues
MLKVAIAEDDFRVAQIQEEFLLKIKDVKVMGKALNAKETMELLQREEIDLLLLDNYLPDGIGTDLLPQIHAEFPNVDVIM
VTAANENHMLEKAIRNGVSNYLIKPVTLEKFVRTIEDYKRKKQLLHNNNEVNQTLIDNFFGISQTQDIKNLPTGVDPLTL
QKVKGIIKGFEEGITIEEMGEQMGASRTTARRYLEYLVATNECTVEYTYGIIGRPERKYRIGRGL

Specific function: Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon [H]

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786838, Length=225, Percent_Identity=36.4444444444444, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1790566, Length=226, Percent_Identity=29.646017699115, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR013196
- InterPro:   IPR001789 [H]

Pfam domain/function: PF08279 HTH_11; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25686; Mature: 25686

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVAIAEDDFRVAQIQEEFLLKIKDVKVMGKALNAKETMELLQREEIDLLLLDNYLPDG
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEECCCCCCC
IGTDLLPQIHAEFPNVDVIMVTAANENHMLEKAIRNGVSNYLIKPVTLEKFVRTIEDYKR
CCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHH
KKQLLHNNNEVNQTLIDNFFGISQTQDIKNLPTGVDPLTLQKVKGIIKGFEEGITIEEMG
HHHHHHCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
EQMGASRTTARRYLEYLVATNECTVEYTYGIIGRPERKYRIGRGL
HHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHCCCCC
>Mature Secondary Structure
MLKVAIAEDDFRVAQIQEEFLLKIKDVKVMGKALNAKETMELLQREEIDLLLLDNYLPDG
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEECCCCCCC
IGTDLLPQIHAEFPNVDVIMVTAANENHMLEKAIRNGVSNYLIKPVTLEKFVRTIEDYKR
CCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHH
KKQLLHNNNEVNQTLIDNFFGISQTQDIKNLPTGVDPLTLQKVKGIIKGFEEGITIEEMG
HHHHHHCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
EQMGASRTTARRYLEYLVATNECTVEYTYGIIGRPERKYRIGRGL
HHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 10972810 [H]