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The map label for this gene is licC [H]

Identifier: 49183778

GI number: 49183778

Start: 808523

End: 809833

Strand: Direct

Name: licC [H]

Synonym: BAS0754

Alternate gene names: 49183778

Gene position: 808523-809833 (Clockwise)

Preceding gene: 49183777

Following gene: 49183779

Centisome position: 15.46

GC content: 35.85

Gene sequence:

>1311_bases
ATGAATGGGTTTATGAGTTTTATGGAACAAAAGATTATGCCAACAACGCAAAAGATTGCCGGACAGCGACATTTATTAGC
AATTCGAAACGGGGTTATTTCTACATTACCGTTAACGATTGTCGGATCATTTTTCGTTATCTTTTTAAACTTACCAATTG
ATGCATATATGGAGTGGATTGCACCGTTTCGCCATATTTTAGATATTCCATTCCGATTTACAGTAGGACTAATGGCATTA
TATGCAGCATTTGGGGTAGGGGCTTCGCTCGCGAACTTTTATCAGCTCAATCAGTTAAGTGCAGGGTTATTATCTGTACT
CGCCTTTTTACTAGCATCAGTTGAACCCATTCAAATTACGAAAGCCGTACCAGGTGTTATTGATGCAGGTAGATATATTT
CAGTAGGAACATTAAGTGCAACATCTTTATTCGGCGCAATTGTTACAGCTTTAATTGCAGTAGAAATTTATCACTTTATG
ATTAAGCATAATATCTCAATTAAATTACCAGATAGTGTACCACCAGCAGTTTCAAATTCATTTGCAGCATTAATTCCAAC
GTTAGCAGTTATTCTTTTATTCTGGGGCATTCGCTACGGTTTGAAATTTGATGTAAATACAACAATCACGTATTTAATCG
CACCATTAAAATCAGTATTAGTAGGAAATAATTTATTCGGCGGTTTATTAACAGTATTCTTAATCGTATTCTTCTGGTCA
TTCGGTATACATGGCCCTGCGATTTTAGGACCAATCATTCGTCCAATGTGGGATTCAGCAATTCTTGAAAATATGGAAGT
ATTCACAGCTACAGGAAATGCACATCAATTACCAAACTTATTTACAGAGCAATTTATTCAATGGTTCGTATGGATTGGTG
GATCAGGCTCAACGTTAGCTTTAGTAATTATGTTTATGTTCTCTAAATCTAAGTTCCTAAAAGAATTAGGTAGATTATCA
TTTGTGCCAGGTTTATTCAATATTAACGAACCGATTATTTTCGGGGCACCAATTGTAATGAATCCAATCTTAATTATTCC
GTTCGTTATTACACCGTTAGTGACAACGACAGTATCATATTTCGCAGTTGTTTCAGGTATGATTCCATTGATGATGGCGA
AACTGCCATTTACGATGTTAGCACCAATTGCAGCGGTTATTAGTACGGACTGGACAATTATGGCTGGTGTACTTGTACTT
GTTAACTTTGTTATCTCATTCGTTATTTACTATCCGTTCTTCAAAATGTATGAGAAACAACAATTAGCAGGAGAGGAGAA
AGAAAAATGCTCGGAGCAATTATCATCTTAA

Upstream 100 bases:

>100_bases
CAATTAGTTTTAGCATAATTATATTTTTTTAAATATAAACATTATAATGTTATAACTTTATTTCATTCTTTCATAGAAAA
GAGAAAGAGGAGGGGTTTTG

Downstream 100 bases:

>100_bases
TTACATTTGTAGCAGGGCAGTGTATTGCACATTATTCAAAATGGGTACAAAGTAAATCGTTATTAGTTTTACTATTAGTA
TCAATTGTATTTATCGGTTG

Product: PTS system cellobiose-specific transporter subunit IIC

Products: protein histidine; sugar phosphate

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MNGFMSFMEQKIMPTTQKIAGQRHLLAIRNGVISTLPLTIVGSFFVIFLNLPIDAYMEWIAPFRHILDIPFRFTVGLMAL
YAAFGVGASLANFYQLNQLSAGLLSVLAFLLASVEPIQITKAVPGVIDAGRYISVGTLSATSLFGAIVTALIAVEIYHFM
IKHNISIKLPDSVPPAVSNSFAALIPTLAVILLFWGIRYGLKFDVNTTITYLIAPLKSVLVGNNLFGGLLTVFLIVFFWS
FGIHGPAILGPIIRPMWDSAILENMEVFTATGNAHQLPNLFTEQFIQWFVWIGGSGSTLALVIMFMFSKSKFLKELGRLS
FVPGLFNINEPIIFGAPIVMNPILIIPFVITPLVTTTVSYFAVVSGMIPLMMAKLPFTMLAPIAAVISTDWTIMAGVLVL
VNFVISFVIYYPFFKMYEKQQLAGEEKEKCSEQLSS

Sequences:

>Translated_436_residues
MNGFMSFMEQKIMPTTQKIAGQRHLLAIRNGVISTLPLTIVGSFFVIFLNLPIDAYMEWIAPFRHILDIPFRFTVGLMAL
YAAFGVGASLANFYQLNQLSAGLLSVLAFLLASVEPIQITKAVPGVIDAGRYISVGTLSATSLFGAIVTALIAVEIYHFM
IKHNISIKLPDSVPPAVSNSFAALIPTLAVILLFWGIRYGLKFDVNTTITYLIAPLKSVLVGNNLFGGLLTVFLIVFFWS
FGIHGPAILGPIIRPMWDSAILENMEVFTATGNAHQLPNLFTEQFIQWFVWIGGSGSTLALVIMFMFSKSKFLKELGRLS
FVPGLFNINEPIIFGAPIVMNPILIIPFVITPLVTTTVSYFAVVSGMIPLMMAKLPFTMLAPIAAVISTDWTIMAGVLVL
VNFVISFVIYYPFFKMYEKQQLAGEEKEKCSEQLSS
>Mature_436_residues
MNGFMSFMEQKIMPTTQKIAGQRHLLAIRNGVISTLPLTIVGSFFVIFLNLPIDAYMEWIAPFRHILDIPFRFTVGLMAL
YAAFGVGASLANFYQLNQLSAGLLSVLAFLLASVEPIQITKAVPGVIDAGRYISVGTLSATSLFGAIVTALIAVEIYHFM
IKHNISIKLPDSVPPAVSNSFAALIPTLAVILLFWGIRYGLKFDVNTTITYLIAPLKSVLVGNNLFGGLLTVFLIVFFWS
FGIHGPAILGPIIRPMWDSAILENMEVFTATGNAHQLPNLFTEQFIQWFVWIGGSGSTLALVIMFMFSKSKFLKELGRLS
FVPGLFNINEPIIFGAPIVMNPILIIPFVITPLVTTTVSYFAVVSGMIPLMMAKLPFTMLAPIAAVISTDWTIMAGVLVL
VNFVISFVIYYPFFKMYEKQQLAGEEKEKCSEQLSS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=466, Percent_Identity=30.2575107296137, Blast_Score=194, Evalue=8e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: 2.7.1.69

Molecular weight: Translated: 47993; Mature: 47993

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGFMSFMEQKIMPTTQKIAGQRHLLAIRNGVISTLPLTIVGSFFVIFLNLPIDAYMEWI
CCHHHHHHHHHCCCHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
APFRHILDIPFRFTVGLMALYAAFGVGASLANFYQLNQLSAGLLSVLAFLLASVEPIQIT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
KAVPGVIDAGRYISVGTLSATSLFGAIVTALIAVEIYHFMIKHNISIKLPDSVPPAVSNS
HHCCCHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHCCH
FAALIPTLAVILLFWGIRYGLKFDVNTTITYLIAPLKSVLVGNNLFGGLLTVFLIVFFWS
HHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FGIHGPAILGPIIRPMWDSAILENMEVFTATGNAHQLPNLFTEQFIQWFVWIGGSGSTLA
HCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHCHHHHHHHHHHHHHHCCCCCHHHH
LVIMFMFSKSKFLKELGRLSFVPGLFNINEPIIFGAPIVMNPILIIPFVITPLVTTTVSY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHH
FAVVSGMIPLMMAKLPFTMLAPIAAVISTDWTIMAGVLVLVNFVISFVIYYPFFKMYEKQ
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLAGEEKEKCSEQLSS
HHCCCHHHHHHHHHCC
>Mature Secondary Structure
MNGFMSFMEQKIMPTTQKIAGQRHLLAIRNGVISTLPLTIVGSFFVIFLNLPIDAYMEWI
CCHHHHHHHHHCCCHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
APFRHILDIPFRFTVGLMALYAAFGVGASLANFYQLNQLSAGLLSVLAFLLASVEPIQIT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
KAVPGVIDAGRYISVGTLSATSLFGAIVTALIAVEIYHFMIKHNISIKLPDSVPPAVSNS
HHCCCHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHCCH
FAALIPTLAVILLFWGIRYGLKFDVNTTITYLIAPLKSVLVGNNLFGGLLTVFLIVFFWS
HHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FGIHGPAILGPIIRPMWDSAILENMEVFTATGNAHQLPNLFTEQFIQWFVWIGGSGSTLA
HCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHCHHHHHHHHHHHHHHCCCCCHHHH
LVIMFMFSKSKFLKELGRLSFVPGLFNINEPIIFGAPIVMNPILIIPFVITPLVTTTVSY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHH
FAVVSGMIPLMMAKLPFTMLAPIAAVISTDWTIMAGVLVLVNFVISFVIYYPFFKMYEKQ
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLAGEEKEKCSEQLSS
HHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]