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The map label for this gene is kdpD [H]

Identifier: 49183730

GI number: 49183730

Start: 766181

End: 767329

Strand: Direct

Name: kdpD [H]

Synonym: BAS0706

Alternate gene names: 49183730

Gene position: 766181-767329 (Clockwise)

Preceding gene: 49183729

Following gene: 49183732

Centisome position: 14.65

GC content: 37.68

Gene sequence:

>1149_bases
GTGTTGTATGCGGATGACTATAAACCGACGTTTCAAAGGCGAACGCCAGAGGAATATTTAGAATATATTCGTCAGCAAAA
TCGTGGGAAGTTAAAGCTATATGTAGGGGCTGCTCCAGGAGTAGGGAAAAGTTATAAAATGCTCTATGATGCTAGAGAGA
TGAAAAAGGACGGTATGGATATTGTAATTGGTTTAATTGAAACGCACGGGAGAAAAGAGACGGAAGAAGCAATTGCTGAT
TTAGAAAAAGTTCCTTTGAAAGAAATACAGTATAAAGGAAAAGTATTTTATGAGCTTGATGTGGAAGGCATTATAAAACG
TGCACCGCAAGTTGTTGTGGTGGATGAACTTGCGCATAGTAATGTTCCTGGATCTAAAAATAAGAAACGCTATATGGATG
TACAGGAATTGATAGATGCCGGTATATCCGTATTATCAGCGTTTAACATCCAACATTTAGAAAGCGTTCATGACATTGTA
GCTCAAATTACAAATGTAAAAGTAAGAGAACGCATTCCAGATTTTATTTTACAAAAAGCAAATGAAATTCAGCTTGTCGA
TGCAACGCCGGAAGTATTAAGGAAGAGACTAATAGACGGAAAGATATATAAAGAAGAAAAAATTCAGCAAAGCTTACAAA
ATTTCTTTACGCTTAATAATTTAGGGGCACTAAGAGAATTATCACTCCGAGAAGTTGCCGATGATATGGACGAGAAAATT
AGCCAAACAGTGATAGAGCCGATTGGCGTGAAAGAAAAAATTCTCGTTTGTGTACAATACAGTTCAACAGCAGAGAAATT
AATAAGACGGGGATGGCGCATGGCGGATCGGCTAAACGCCGAATTGTATGTATTAAATGTTGAAAGGGAAAAGATAGATT
CTCTTTCAGCGGGGAAAAAGCAAACGATTGAAGAGTGGAAGTCGCTAACGAATCAATTTGATGCGAGTTTTGTATTAGAA
GAAGCGAACGGAAGAAAGCCAGCGGATGTTATTATTGAAGTGGCGAAAAGACTGCAAGTAACGCAAATTTTACTTGGACA
GTCGGCGAGAACAAGGTGGGATGAAATTCGAAAAGGTTCGATTGTAAATGAAATTATGAGAGAAACGAAGTATATTGATA
TTCATATCGTTGCGGATCAAAGAGCTTAA

Upstream 100 bases:

>100_bases
TAAAGTTAAATTTAGGGTTACAGAAAATAATGAAATAGTAACAGTGCTACCTCAATCTAATGGATTGGGGTAGTGTTGTT
TCGAAAGAAAGGTTGTGTGT

Downstream 100 bases:

>100_bases
AATAGAGCCGACCTTTTGGGGGCTCTATTTTACTTTTTGTGTGGTAGGGAAGCGTAGCATTTTCATCGCATATAAGATTA
TGAGTAGAAACATAATTGCT

Product: sensor histidine kinase KdpD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MLYADDYKPTFQRRTPEEYLEYIRQQNRGKLKLYVGAAPGVGKSYKMLYDAREMKKDGMDIVIGLIETHGRKETEEAIAD
LEKVPLKEIQYKGKVFYELDVEGIIKRAPQVVVVDELAHSNVPGSKNKKRYMDVQELIDAGISVLSAFNIQHLESVHDIV
AQITNVKVRERIPDFILQKANEIQLVDATPEVLRKRLIDGKIYKEEKIQQSLQNFFTLNNLGALRELSLREVADDMDEKI
SQTVIEPIGVKEKILVCVQYSSTAEKLIRRGWRMADRLNAELYVLNVEREKIDSLSAGKKQTIEEWKSLTNQFDASFVLE
EANGRKPADVIIEVAKRLQVTQILLGQSARTRWDEIRKGSIVNEIMRETKYIDIHIVADQRA

Sequences:

>Translated_382_residues
MLYADDYKPTFQRRTPEEYLEYIRQQNRGKLKLYVGAAPGVGKSYKMLYDAREMKKDGMDIVIGLIETHGRKETEEAIAD
LEKVPLKEIQYKGKVFYELDVEGIIKRAPQVVVVDELAHSNVPGSKNKKRYMDVQELIDAGISVLSAFNIQHLESVHDIV
AQITNVKVRERIPDFILQKANEIQLVDATPEVLRKRLIDGKIYKEEKIQQSLQNFFTLNNLGALRELSLREVADDMDEKI
SQTVIEPIGVKEKILVCVQYSSTAEKLIRRGWRMADRLNAELYVLNVEREKIDSLSAGKKQTIEEWKSLTNQFDASFVLE
EANGRKPADVIIEVAKRLQVTQILLGQSARTRWDEIRKGSIVNEIMRETKYIDIHIVADQRA
>Mature_382_residues
MLYADDYKPTFQRRTPEEYLEYIRQQNRGKLKLYVGAAPGVGKSYKMLYDAREMKKDGMDIVIGLIETHGRKETEEAIAD
LEKVPLKEIQYKGKVFYELDVEGIIKRAPQVVVVDELAHSNVPGSKNKKRYMDVQELIDAGISVLSAFNIQHLESVHDIV
AQITNVKVRERIPDFILQKANEIQLVDATPEVLRKRLIDGKIYKEEKIQQSLQNFFTLNNLGALRELSLREVADDMDEKI
SQTVIEPIGVKEKILVCVQYSSTAEKLIRRGWRMADRLNAELYVLNVEREKIDSLSAGKKQTIEEWKSLTNQFDASFVLE
EANGRKPADVIIEVAKRLQVTQILLGQSARTRWDEIRKGSIVNEIMRETKYIDIHIVADQRA

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=373, Percent_Identity=36.1930294906166, Blast_Score=261, Evalue=8e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02702 KdpD; PF00582 Usp [H]

EC number: 2.7.3.-

Molecular weight: Translated: 43903; Mature: 43903

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYADDYKPTFQRRTPEEYLEYIRQQNRGKLKLYVGAAPGVGKSYKMLYDAREMKKDGMD
CCCCCCCCCCHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHH
IVIGLIETHGRKETEEAIADLEKVPLKEIQYKGKVFYELDVEGIIKRAPQVVVVDELAHS
EEEEHHHCCCCCHHHHHHHHHHHCCHHHHCCCCCEEEEECHHHHHHHCCCEEEEEHHHCC
NVPGSKNKKRYMDVQELIDAGISVLSAFNIQHLESVHDIVAQITNVKVRERIPDFILQKA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCHHHHHCCC
NEIQLVDATPEVLRKRLIDGKIYKEEKIQQSLQNFFTLNNLGALRELSLREVADDMDEKI
CCEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
SQTVIEPIGVKEKILVCVQYSSTAEKLIRRGWRMADRLNAELYVLNVEREKIDSLSAGKK
HHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCHH
QTIEEWKSLTNQFDASFVLEEANGRKPADVIIEVAKRLQVTQILLGQSARTRWDEIRKGS
HHHHHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCH
IVNEIMRETKYIDIHIVADQRA
HHHHHHHHCCEEEEEEEECCCC
>Mature Secondary Structure
MLYADDYKPTFQRRTPEEYLEYIRQQNRGKLKLYVGAAPGVGKSYKMLYDAREMKKDGMD
CCCCCCCCCCHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHH
IVIGLIETHGRKETEEAIADLEKVPLKEIQYKGKVFYELDVEGIIKRAPQVVVVDELAHS
EEEEHHHCCCCCHHHHHHHHHHHCCHHHHCCCCCEEEEECHHHHHHHCCCEEEEEHHHCC
NVPGSKNKKRYMDVQELIDAGISVLSAFNIQHLESVHDIVAQITNVKVRERIPDFILQKA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCHHHHHCCC
NEIQLVDATPEVLRKRLIDGKIYKEEKIQQSLQNFFTLNNLGALRELSLREVADDMDEKI
CCEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
SQTVIEPIGVKEKILVCVQYSSTAEKLIRRGWRMADRLNAELYVLNVEREKIDSLSAGKK
HHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCHH
QTIEEWKSLTNQFDASFVLEEANGRKPADVIIEVAKRLQVTQILLGQSARTRWDEIRKGS
HHHHHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCH
IVNEIMRETKYIDIHIVADQRA
HHHHHHHHCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]