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The map label for this gene is rocE [H]

Identifier: 49183635

GI number: 49183635

Start: 660464

End: 661891

Strand: Direct

Name: rocE [H]

Synonym: BAS0610

Alternate gene names: 49183635

Gene position: 660464-661891 (Clockwise)

Preceding gene: 49183634

Following gene: 49183636

Centisome position: 12.63

GC content: 37.11

Gene sequence:

>1428_bases
ATGCAGCAAACAACGAATGAGAAATTACATCGTACGATGAAGAGTAGACATTTATTTATGATCGCACTAGGTGGTGTAAT
CGGAACAGGTTTTTTCTTAGGTTCGGGTTACACCATTAATCAGGCTGGACCAGGGGGAGCCATCCTTTCATATTTAGTAG
GCGGATTCATTATGTATTTAACAATGCTATGCCTTGGAGAGTTAACGGTAGCAATGCCAGTTTCAGGATCTTTCCAAAAG
TATGCGACGAAGTTTATTGGACCAGGAACGGGCTTTATGATTGGCTGGCTATATTGGCTTGGCTGGGCAGTAACAGTAGG
ACTAGAATTAACGTCAATTGGTTTAATGATGAAGAGATGGTTTCCGAATGTTGATGTTTGGGTATGGTGTCTCGTCTTCG
GCGTTATTTTATATGCGTCAAACGCAATTTCAGCGAAAAGTTATGCTGAATTAGAATTTTGGTTCTCTAGTATTAAAGTA
ATTACAATTCTTGCATTTGTTGTTCTTGGTGGTAGTGCATTATTAGGGTTTATATCATATGACGGAAAAGAAGCAGCACC
TCTTTTCTCTAACTTTGTAAGCGAAGGCGGGTTATTCCCGAATGGATTAGCTGCCGTATTACTTACAATGATTACAGTTA
ACTTCTCGTTCCAAGGAACAGAGTTAATCGGAATTGCAGCGGGAGAAAGTGAAAATCCAGAAAAAACAATTCCACGTGCC
ATCCGTAATACAGTATGGCGCATTATGTTATTCTTCATTTTAACAATGACGATTTTAGTAGGATTAATTTCTTGGAAAGA
AGCAGGCGTAATTGAAAGTCCATTCGTAGTCGTATTTGATAAAATCGGTATTCCATACGCAGCTGATATTATGAACTTCG
TTATTATTACTGCGTTATTATCTGTAGCGAACTCTGGATTATATGCAGCGACGCGTATACTATGGTCACTTGCAAATGAA
GGAATGGCACCAACATCTTTCCAAAAAGTAAATAAGCGTGGGATTCCAATTACCGCATTAGTTGTAACGATTGCTGTAGC
TGGCCTTTCTTTATTCACAAGTTTCCTTGCAGAAGATACAGTATACATGTACTTATTATCTATAGCTGGTTTATCAGCTG
TTTCAAGTTGGATCATTATTGCTTTATCGCAACTACGCTTTAGAAGTCAGTATATAAAAGGCGGAGGAAAGTTAGAGGAT
TTAAAATATAGAACACCGCTATATCCAATTGTTCCTATTTTAGCTTTAATTACAAATAGTATCGTTGTTATTAGTTTAGC
GTTTATTCCAGAACAACGAATGGCGTTATATTGTGGTATTCCATTTATCATTTTCTGCTATATATATTATTATATAAATA
AGAAACGGCAGAAACCGATGAAAGTGGAGATGGAAAAAGCAAATGAAACTAACAATCAAACACGATGA

Upstream 100 bases:

>100_bases
AGTTTTAATTTTATATAGAAAATGTAATCGCTTTCGTGTATATTTTTATTATCAGAAAATTTTAACAAGATATAGGGGTA
TTGGTAGGGGGAGGATTTAG

Downstream 100 bases:

>100_bases
CATTGAGGCAGATTTATCGTATGGTCCATTAGCGATTGGAAAAGAAAACGGGTATTCACCGTTACAATTACTCGTTTCTT
CTATCGCAGGATGCAGTGCA

Product: amino acid ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MQQTTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYLTMLCLGELTVAMPVSGSFQK
YATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRWFPNVDVWVWCLVFGVILYASNAISAKSYAELEFWFSSIKV
ITILAFVVLGGSALLGFISYDGKEAAPLFSNFVSEGGLFPNGLAAVLLTMITVNFSFQGTELIGIAAGESENPEKTIPRA
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALLSVANSGLYAATRILWSLANE
GMAPTSFQKVNKRGIPITALVVTIAVAGLSLFTSFLAEDTVYMYLLSIAGLSAVSSWIIIALSQLRFRSQYIKGGGKLED
LKYRTPLYPIVPILALITNSIVVISLAFIPEQRMALYCGIPFIIFCYIYYYINKKRQKPMKVEMEKANETNNQTR

Sequences:

>Translated_475_residues
MQQTTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYLTMLCLGELTVAMPVSGSFQK
YATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRWFPNVDVWVWCLVFGVILYASNAISAKSYAELEFWFSSIKV
ITILAFVVLGGSALLGFISYDGKEAAPLFSNFVSEGGLFPNGLAAVLLTMITVNFSFQGTELIGIAAGESENPEKTIPRA
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALLSVANSGLYAATRILWSLANE
GMAPTSFQKVNKRGIPITALVVTIAVAGLSLFTSFLAEDTVYMYLLSIAGLSAVSSWIIIALSQLRFRSQYIKGGGKLED
LKYRTPLYPIVPILALITNSIVVISLAFIPEQRMALYCGIPFIIFCYIYYYINKKRQKPMKVEMEKANETNNQTR
>Mature_475_residues
MQQTTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYLTMLCLGELTVAMPVSGSFQK
YATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRWFPNVDVWVWCLVFGVILYASNAISAKSYAELEFWFSSIKV
ITILAFVVLGGSALLGFISYDGKEAAPLFSNFVSEGGLFPNGLAAVLLTMITVNFSFQGTELIGIAAGESENPEKTIPRA
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALLSVANSGLYAATRILWSLANE
GMAPTSFQKVNKRGIPITALVVTIAVAGLSLFTSFLAEDTVYMYLLSIAGLSAVSSWIIIALSQLRFRSQYIKGGGKLED
LKYRTPLYPIVPILALITNSIVVISLAFIPEQRMALYCGIPFIIFCYIYYYINKKRQKPMKVEMEKANETNNQTR

Specific function: Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine [H]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=351, Percent_Identity=25.6410256410256, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI71999149, Length=350, Percent_Identity=23.1428571428571, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI258645169, Length=430, Percent_Identity=22.7906976744186, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87081708, Length=470, Percent_Identity=50.6382978723404, Blast_Score=497, Evalue=1e-142,
Organism=Escherichia coli, GI1788480, Length=480, Percent_Identity=41.25, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI1786302, Length=461, Percent_Identity=36.0086767895879, Blast_Score=308, Evalue=6e-85,
Organism=Escherichia coli, GI1786789, Length=457, Percent_Identity=35.8862144420131, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI1789017, Length=434, Percent_Identity=36.405529953917, Blast_Score=281, Evalue=6e-77,
Organism=Escherichia coli, GI48994972, Length=463, Percent_Identity=33.6933045356371, Blast_Score=278, Evalue=4e-76,
Organism=Escherichia coli, GI87081915, Length=406, Percent_Identity=37.6847290640394, Blast_Score=278, Evalue=6e-76,
Organism=Escherichia coli, GI1786602, Length=457, Percent_Identity=35.4485776805252, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI1790653, Length=464, Percent_Identity=32.5431034482759, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI87081869, Length=239, Percent_Identity=25.1046025104602, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367353, Length=346, Percent_Identity=24.2774566473988, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=427, Percent_Identity=21.7798594847775, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540018, Length=363, Percent_Identity=24.5179063360882, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=441, Percent_Identity=24.4897959183673, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320772, Length=443, Percent_Identity=32.7313769751693, Blast_Score=252, Evalue=9e-68,
Organism=Saccharomyces cerevisiae, GI6324061, Length=421, Percent_Identity=33.4916864608076, Blast_Score=249, Evalue=9e-67,
Organism=Saccharomyces cerevisiae, GI6320717, Length=486, Percent_Identity=30.2469135802469, Blast_Score=226, Evalue=9e-60,
Organism=Saccharomyces cerevisiae, GI6324553, Length=407, Percent_Identity=31.6953316953317, Blast_Score=224, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6324059, Length=440, Percent_Identity=31.5909090909091, Blast_Score=220, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6324990, Length=473, Percent_Identity=29.5983086680761, Blast_Score=210, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6319824, Length=490, Percent_Identity=29.7959183673469, Blast_Score=210, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6322892, Length=477, Percent_Identity=30.8176100628931, Blast_Score=207, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6320251, Length=421, Percent_Identity=31.5914489311164, Blast_Score=206, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6319542, Length=416, Percent_Identity=31.9711538461538, Blast_Score=206, Evalue=8e-54,
Organism=Saccharomyces cerevisiae, GI6321629, Length=417, Percent_Identity=29.7362110311751, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6319543, Length=420, Percent_Identity=29.7619047619048, Blast_Score=204, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6322967, Length=505, Percent_Identity=27.9207920792079, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6321053, Length=417, Percent_Identity=26.378896882494, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324924, Length=451, Percent_Identity=28.8248337028825, Blast_Score=186, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6324981, Length=509, Percent_Identity=28.2907662082515, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6319608, Length=439, Percent_Identity=25.7403189066059, Blast_Score=160, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6320364, Length=569, Percent_Identity=22.6713532513181, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24667468, Length=408, Percent_Identity=24.7549019607843, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI221512776, Length=431, Percent_Identity=19.7215777262181, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24666159, Length=431, Percent_Identity=19.7215777262181, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52301; Mature: 52301

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQTTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYL
CCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHH
TMLCLGELTVAMPVSGSFQKYATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRW
HHHHHHHHHEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPNVDVWVWCLVFGVILYASNAISAKSYAELEFWFSSIKVITILAFVVLGGSALLGFISY
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCC
DGKEAAPLFSNFVSEGGLFPNGLAAVLLTMITVNFSFQGTELIGIAAGESENPEKTIPRA
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SVANSGLYAATRILWSLANEGMAPTSFQKVNKRGIPITALVVTIAVAGLSLFTSFLAEDT
HHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VYMYLLSIAGLSAVSSWIIIALSQLRFRSQYIKGGGKLEDLKYRTPLYPIVPILALITNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCC
IVVISLAFIPEQRMALYCGIPFIIFCYIYYYINKKRQKPMKVEMEKANETNNQTR
HHEEHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCC
>Mature Secondary Structure
MQQTTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYL
CCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHH
TMLCLGELTVAMPVSGSFQKYATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRW
HHHHHHHHHEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPNVDVWVWCLVFGVILYASNAISAKSYAELEFWFSSIKVITILAFVVLGGSALLGFISY
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCC
DGKEAAPLFSNFVSEGGLFPNGLAAVLLTMITVNFSFQGTELIGIAAGESENPEKTIPRA
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SVANSGLYAATRILWSLANEGMAPTSFQKVNKRGIPITALVVTIAVAGLSLFTSFLAEDT
HHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VYMYLLSIAGLSAVSSWIIIALSQLRFRSQYIKGGGKLEDLKYRTPLYPIVPILALITNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCC
IVVISLAFIPEQRMALYCGIPFIIFCYIYYYINKKRQKPMKVEMEKANETNNQTR
HHEEHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7540694; 9384377 [H]