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The map label for this gene is murI [H]

Identifier: 46447487

GI number: 46447487

Start: 2213529

End: 2214278

Strand: Direct

Name: murI [H]

Synonym: pc1853

Alternate gene names: 46447487

Gene position: 2213529-2214278 (Clockwise)

Preceding gene: 46447486

Following gene: 46447490

Centisome position: 91.68

GC content: 37.87

Gene sequence:

>750_bases
ATGCGAGAAATGATTCGTTTGCTGCCCCAAGAGAACCTCTTGTATCTTGGGGATACAGCAAGAGTACCCTATGGAAATAA
GAGCGCAGCAACAATTATTCGCTATAGCATTGAAAATGCTATTTTTCTACTTGAAAAGCAAATTAAAGTATTGGTGGTTG
CTTGTAATACAGCCTCAGCTTTAGCGCTTCCAAAATTAAAACAGCTCTTTCACCTCCCAATCATAGGCGTCATTGAACCT
GGGGCTAAATTAGCAGCTGCAACAACGCGTAACAAACGTATAGCCGTTTTAGGAACTAAAGGAACCATTGAATCTGGTGC
TTACCAGTCTGCAATTCATCAACTAATTCCTGATGCGATTATCTTTCCAATTGCATGTCCTCTATTGGTTTCTCTCGTTG
AAGAAGGTTTTCTCTATCATTCTGCTTCAAAACTCATTATCCAAGAATATTTAAAAAATTTAGAGAAGGCAGATGTCGAT
ACTATTTTGCTTGGTTGCACCCATTATCCTTTACTTAAACCCCTCATTGAAGAAATAATGGGCTCATCTGTTACAATTAT
AGATTCAGCCTTGACCTGTGCCCAAACCGTCAAAAAACTTTTAGAAAGTCATCAACTTGTCAATTCGAATCAACACGCAA
TTCACCAATATTTCGTCACAGATGATCCAGAGAAATTTCGCCAACTTGGTGAATATTTGTTTCAATCTCCTCTTCCTTTA
GTAGAATTGCACAAAATAATTCATTCGTAA

Upstream 100 bases:

>100_bases
CGGACAAGTACTTAAACTTCCTTAATCTATGGCATTCAATCACCTTGCTTCTTCTCATGCTATTGGTTTATTTGACTCAG
GGATAGGGGGGTTAACAGTC

Downstream 100 bases:

>100_bases
TCTATTTGAGTTCAGTCAATTAAAAACCAACTTGTCGCATTTTGTTAGAAAAATTTAATTGTATATTCCCTGCGAAAATA
ATAACATTTGTTATTTCTTT

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MREMIRLLPQENLLYLGDTARVPYGNKSAATIIRYSIENAIFLLEKQIKVLVVACNTASALALPKLKQLFHLPIIGVIEP
GAKLAAATTRNKRIAVLGTKGTIESGAYQSAIHQLIPDAIIFPIACPLLVSLVEEGFLYHSASKLIIQEYLKNLEKADVD
TILLGCTHYPLLKPLIEEIMGSSVTIIDSALTCAQTVKKLLESHQLVNSNQHAIHQYFVTDDPEKFRQLGEYLFQSPLPL
VELHKIIHS

Sequences:

>Translated_249_residues
MREMIRLLPQENLLYLGDTARVPYGNKSAATIIRYSIENAIFLLEKQIKVLVVACNTASALALPKLKQLFHLPIIGVIEP
GAKLAAATTRNKRIAVLGTKGTIESGAYQSAIHQLIPDAIIFPIACPLLVSLVEEGFLYHSASKLIIQEYLKNLEKADVD
TILLGCTHYPLLKPLIEEIMGSSVTIIDSALTCAQTVKKLLESHQLVNSNQHAIHQYFVTDDPEKFRQLGEYLFQSPLPL
VELHKIIHS
>Mature_249_residues
MREMIRLLPQENLLYLGDTARVPYGNKSAATIIRYSIENAIFLLEKQIKVLVVACNTASALALPKLKQLFHLPIIGVIEP
GAKLAAATTRNKRIAVLGTKGTIESGAYQSAIHQLIPDAIIFPIACPLLVSLVEEGFLYHSASKLIIQEYLKNLEKADVD
TILLGCTHYPLLKPLIEEIMGSSVTIIDSALTCAQTVKKLLESHQLVNSNQHAIHQYFVTDDPEKFRQLGEYLFQSPLPL
VELHKIIHS

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis [H]

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family [H]

Homologues:

Organism=Escherichia coli, GI87082355, Length=205, Percent_Identity=31.7073170731707, Blast_Score=91, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391 [H]

Pfam domain/function: PF01177 Asp_Glu_race [H]

EC number: =5.1.1.3 [H]

Molecular weight: Translated: 27615; Mature: 27615

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS00923 ASP_GLU_RACEMASE_1 ; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREMIRLLPQENLLYLGDTARVPYGNKSAATIIRYSIENAIFLLEKQIKVLVVACNTASA
CCHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEEECCCHH
LALPKLKQLFHLPIIGVIEPGAKLAAATTRNKRIAVLGTKGTIESGAYQSAIHQLIPDAI
HHHHHHHHHHHCCCEEEECCCCCEEHEECCCCEEEEEECCCCCCCHHHHHHHHHHCCHHH
IFPIACPLLVSLVEEGFLYHSASKLIIQEYLKNLEKADVDTILLGCTHYPLLKPLIEEIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHHHHHC
GSSVTIIDSALTCAQTVKKLLESHQLVNSNQHAIHQYFVTDDPEKFRQLGEYLFQSPLPL
CCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCHHHHHHHHHHHHHCCCCH
VELHKIIHS
HHHHHHHCC
>Mature Secondary Structure
MREMIRLLPQENLLYLGDTARVPYGNKSAATIIRYSIENAIFLLEKQIKVLVVACNTASA
CCHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEEECCCHH
LALPKLKQLFHLPIIGVIEPGAKLAAATTRNKRIAVLGTKGTIESGAYQSAIHQLIPDAI
HHHHHHHHHHHCCCEEEECCCCCEEHEECCCCEEEEEECCCCCCCHHHHHHHHHHCCHHH
IFPIACPLLVSLVEEGFLYHSASKLIIQEYLKNLEKADVDTILLGCTHYPLLKPLIEEIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHHHHHC
GSSVTIIDSALTCAQTVKKLLESHQLVNSNQHAIHQYFVTDDPEKFRQLGEYLFQSPLPL
CCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCHHHHHHHHHHHHHCCCCH
VELHKIIHS
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA