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The map label for this gene is guaD [H]

Identifier: 46447463

GI number: 46447463

Start: 2184720

End: 2185190

Strand: Direct

Name: guaD [H]

Synonym: pc1829

Alternate gene names: 46447463

Gene position: 2184720-2185190 (Clockwise)

Preceding gene: 46447460

Following gene: 46447464

Centisome position: 90.48

GC content: 38.22

Gene sequence:

>471_bases
ATGTTTGATTATATGAGGCGTGCTATTGAAAGTGCTTATGAAGGAATTGATAAAGATGAGGGTGGTCCATTTGGAGCTTG
TATTGTCGACAAACAAGGCCAAATACTAGCTGTCACACATAATACTGTGTTGAAAGATCAGGATCCAACTTGCCATGCAG
AAATGAATTGTATTCGCGAAGCTGCTCGTCGTTTAAAGACTCACATTTTATCAGGATATACATTATTTACGACCGCAGAA
CCATGTCCCATGTGCTTGGCAGCTATTTATTGGGCTCGAATTGAAAAAGTGTACATAGGTGTAAAAAAAGAGTGTGCTGC
CCGTTATGGATTTGACGACGCTTTTTTTTACGAACAATTATTACTACCCCCGGAAAAAAGAGAGGTTCTAGCTACATTTG
ATCCAGATTCTTCAAAACAATGTGAAGAAATTTTTGTTAAATGGCATTCATTAAACAGGCGGCTCTATTAA

Upstream 100 bases:

>100_bases
AAATATCATTAAGAAAATGTCTAAATATAGAGGAATAGAGAGAACCTTAGTCAAACTAAGGATTTTCATCATTAATTTTT
TTTAATTCGAGAATGAAGAT

Downstream 100 bases:

>100_bases
AAACGATATGAAAACAGATGAAATTACCATTTCACATCCTAAAAATAGAGAGGTAAACAAAACAAAACAAATAAATTTTT
ATATTAAAAAATTTTTAATT

Product: hypothetical protein

Products: NA

Alternate protein names: GDEase; Guanase; Guanine aminase; Guanine aminohydrolase; GAH [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MFDYMRRAIESAYEGIDKDEGGPFGACIVDKQGQILAVTHNTVLKDQDPTCHAEMNCIREAARRLKTHILSGYTLFTTAE
PCPMCLAAIYWARIEKVYIGVKKECAARYGFDDAFFYEQLLLPPEKREVLATFDPDSSKQCEEIFVKWHSLNRRLY

Sequences:

>Translated_156_residues
MFDYMRRAIESAYEGIDKDEGGPFGACIVDKQGQILAVTHNTVLKDQDPTCHAEMNCIREAARRLKTHILSGYTLFTTAE
PCPMCLAAIYWARIEKVYIGVKKECAARYGFDDAFFYEQLLLPPEKREVLATFDPDSSKQCEEIFVKWHSLNRRLY
>Mature_156_residues
MFDYMRRAIESAYEGIDKDEGGPFGACIVDKQGQILAVTHNTVLKDQDPTCHAEMNCIREAARRLKTHILSGYTLFTTAE
PCPMCLAAIYWARIEKVYIGVKKECAARYGFDDAFFYEQLLLPPEKREVLATFDPDSSKQCEEIFVKWHSLNRRLY

Specific function: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17555996, Length=127, Percent_Identity=42.5196850393701, Blast_Score=117, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17554608, Length=156, Percent_Identity=38.4615384615385, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.3 [H]

Molecular weight: Translated: 17955; Mature: 17955

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDYMRRAIESAYEGIDKDEGGPFGACIVDKQGQILAVTHNTVLKDQDPTCHAEMNCIRE
CHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECCCEECCCCCCHHHHHHHHHH
AARRLKTHILSGYTLFTTAEPCPMCLAAIYWARIEKVYIGVKKECAARYGFDDAFFYEQL
HHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHH
LLPPEKREVLATFDPDSSKQCEEIFVKWHSLNRRLY
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFDYMRRAIESAYEGIDKDEGGPFGACIVDKQGQILAVTHNTVLKDQDPTCHAEMNCIRE
CHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECCCEECCCCCCHHHHHHHHHH
AARRLKTHILSGYTLFTTAEPCPMCLAAIYWARIEKVYIGVKKECAARYGFDDAFFYEQL
HHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHH
LLPPEKREVLATFDPDSSKQCEEIFVKWHSLNRRLY
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11101664 [H]